• 한국신뢰성학회지:신뢰성응용연구
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• 제1권1호
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• pp.47-54
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• 2001

This paper considers the parameter estimation problem of the failure intensity function and maintenance effect in a repairable system. We propose estimation procedures for repairable systems on which preventive maintenance is performed. The failure process is modeled by a proportional age reduction model [Brown, Mahoney and Sivazlian(1983)] which is useful to model the imperfect effect of preventive maintenance. When failure and maintenance (preventive) times are given, the maximum likelihood method is used to estimate the maintenance effect and the parameters of intensity function, simultaneously We obtain the maximum likelihood estimators using a genetic algorithm. A numerical example is also presented.

• 동의생리병리학회지
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• 제20권1호
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• pp.98-102
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• 2006

The present stuby was carried out to determine if Radix Glycyrrhizae extract exerts beneficial effect against the ischemia-induced acute renal failure in rabbits. Radix Glycyrrhizae was known to reinforce the function of the spleen and replenish Qi, remove heat and counteract toxicity, dispel phlegm and relieve cough, alleviate spasmodic pain, and to moderate drug actions. It's indications are weakness of the spleen and the stomach marked by lassitude and weakness; cardiac palpitation and shortness of breath; cough with much phlegm; spasmodic pain in the epigastrium, abdomen and limbs; carbuncles and sores. It is often used for reducing the toxic or drastic actions of other drugs. Rabbits were treated with Radix Glycyrrhizae extract via i.v., followed by renal ischemia/reperfusion. Fractional excretion of glucose and phosphate, lipid peroxidation and light microscopy were done to evaluate the beneficial effect of Radix Glycyrrhizae extract on ischemia/reperfusion induced acute renal failure. Renal ischemia/reperfusion caused increase of fractional excretion of glucose and phosphate increased in ischemia-induced animals, which was partially prevented by Radix Glycyrrhizae extract treatment. Ischemia/reperfusion increased lipid peroxidation, which was prevented by Radix Glycyrrhizae extract administration. And the beneficial effect of Radix Glycyrrhizae extract on ischemia/reperfusion induced kidney injury was shown through the light micrographic observation. These results indicate that lipid peroxidation plays a critical role in ischemia-induced acute renal failure. Radix Glycyrrhizae extract exerts the protective effect against acute renal failure induced by renal ischemia/reperfusion.

• 품질경영학회지
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• 제47권3호
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• pp.571-582
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• 2019

Purpose: To develop a risk metric for failure cause that can help determine the action priority of each failure cause in FMEA considering time sequence of cause- failure- detection. Methods: Assuming a quadratic loss function the unfulfilled mission period, a risk metric is obtained by deriving the failure time distribution. Results: The proposed risk metric has some reasonable properties for evaluating risk accompanied with a failure cause. Conclusion: The study may be applied to determining action priorities among all the failure causes in the FMEA sheet, requiring further studies for general situation of failure process.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2002년도 봄 학술발표회 논문집
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• pp.793-798
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• 2002

This paper presents the analytical results on the seismic retrofit of circular bridge columns with poor lap-splice details using FRP jacket. The as-built column suffered brittle failure due to the deterioration of lap-spliced longitudinal reinforcement without developing its flexural capacity or ductility. The retrofitted columns using FRP jacket showed significant improvement in seismic performance due to FRP's confinement effect. FRP's confinement effect is predicted by the classical elasticity solution for the laminated circular tube manufactural with several layers, and induces the flexural failure instead of bondslip failure.

• Computers and Concrete
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• 제6권5호
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• pp.403-419
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• 2009

Short column effect is cause to failure of columns which may result in severe damages or even collapse during earthquakes. The scope of the study is mainly to reveal the effect of short column on the holistic behaviour of the buildings. The nonlinear analysis of 31 different frame buildings containing short column problem are carried out using finite element method. The finite element models were selected by 2 bays and 3 stories. Since the short columns are generally seen in the first storey of the buildings, in the study, they are only constructed in the same storey. The adverse effect of the short column on the response of buildings was shown in terms of the total load factor and displacement capacity of building. The response of buildings in terms of ground storey displacements is presented in figures and discussed. It is revealed that if the window openings are constructed along the bays, the total load capacity is decreased 85% compared with reference model in which all of bays are filled with infill walls.

• 대한한의학회지
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• 제22권1호
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• pp.33-45
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• 2001

Objectives: This experimental study was carried out to prove the effect of Saenghyuldan(SHD; shengxiedan) on bone marrow failure induced by cyclophosphamide(CY) and irradiation in mice. Methods: The following were performed; immunopathology, histopathlogical findings of bone marrow and in the smear of myelocyte. hematopoietic cytokine(IL-3, GM-CSF, TPO), hematopoietic stem cell colony assay, humoral immunity(LPS mitogen response), cell-mediated immunity (Con A mitogen response) and nonspecific immunity(macrophage adherence & phagocytosis) in vitro or vivo. Results: SHD showed a protective effect on bone marrow failure induced by cyclophosphamide(CY) and irradiation in mice. SHD increased lymphoproliferative responses to LPS and Con A, and activated macrophage adherence and phagocytosis to SRBC. Conclusions: We expect that SHD can be used to treat bone marrow failure and immune suppression induced by the chemotherapy or radiation.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2000년도 가을 학술발표회 논문집
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• pp.511-518
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• 2000

Characteristics of joint orientation, length, spacing and their distribution are very important factors for slope stability, Especially, the effect of joint spacing is an essential factor of slope stability. This study is to analyze the effect of joint spacing in cases of sliding and toppling, which is a typical failure mode. Joint spacing can divided into vertical spacing(spacing) and horizontal spacing(gap). And then, the spacing/length ratio of joint directly affect rock slope failure. When the ratio is below 0.05, the possibility of failure is rapidly increased. In case of toppling, the possibility of failure depends on the ratio of spacing to height of slope ratio slope. As the ratio decreases, the possibility of toppling failure increased. The critical ratio of spacing to height of slope is determined by the dip angle of the slope and the orientation of joint sets.

• 대한기계학회논문집A
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• 제23권11호
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• pp.2096-2101
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• 1999

This paper presents the effect of shape of external corrosion in pipeline on failure prediction by using numerical simulation. The numerical study for the pipeline failure analysis is based on the FEM(Finite Element Method) with an elastic-plastic and large-deformation analysis. The predicted failure stress assessed for the simulated corrosion defects having different corroded shapes along the pipeline axis are compared with those by methods specified in ANSl/ASME B31G code and a modified B31G code.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2000년도 봄 학술발표회 논문집
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• pp.781-786
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• 2000

This paper presents the behavior and strenghening effect of reinforced concrete rectangular beams strengthened sing CFRP sheets with different strengthening level. In general, normally strengthened beams are failed by interfacial shear failure (delamination) within concrete, instead of by tensile failure of the CFRP sheets. The delamination occurred suddenly and the concrete cover cracked vertically by flexure was spalled off due to the release energy. The ultimate load considerably increased with an increase of strengthening level, while the ultimate deflection significantly decreased. The tensile force of CFRP sheets and average shear stress of concrete at delamination failure were curvilinearly proportional to the strengthening level. Therefore, the increment of ultimate load obtained by strengthening was curvilinearly proportional to th strengthening level.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1988년도 학술세미나 강연집
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• pp.71-123
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• 1988

The aim of this paper is to examine the end bearing capacity of a pile in cohesionless soils. The ode of failure of soil due to pile installation is assumed from experimental observation of actual soil deformation. A new solution is proposed complying with the assumed mode of failure by employing the theory of cavity expansion. The effect of curvature of failure envelope is studied in relation to tile proposed solution. The influence of a curved failure envelope becomes larger with increasing degree of curvature and the level of confining stress. This effect in some cases or reduce the end bearing capacity by tore the 80 percent compared with that given by a straight failure envelope. For practical application of tile proposed solution, the method of determining the average volume change in the plastic zone is re-evaluated. The proposed solution is confirmed by comparing the theoretical values with experimental results obtained from model pile tests in a calibration chamber. The comparison shows that the proposed solution provides a reasonable prediction of end bearing capacity for both weak and strong grained soils.