• Title/Summary/Keyword: Factorial test

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Relation between Multiple Markers of Work-Related Fatigue

  • Volker, Ina;Kirchner, Christine;Bock, Otmar L.
    • Safety and Health at Work
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    • v.7 no.2
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    • pp.124-129
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    • 2016
  • Background: Work-related fatigue has a strong impact on performance and safety but so far, no agreed upon method exists to detect and quantify it. It has been suggested that work-related fatigue cannot be quantified with just one test alone, possibly because fatigue is not a uniform construct. The purpose of this study is therefore to measure work-related fatigue with multiple tests and then to determine the underlying factorial structure. Methods: Twenty-eight employees (mean: 36.11; standard deviation 13.17) participated in five common fatigue tests, namely, posturography, heart rate variability, distributed attention, simple reaction time, and subjective fatigue before and after work. To evaluate changes from morning to afternoon, t tests were conducted. For further data analysis, the differences between afternoon and morning scores for each outcome measure and participant (${\Delta}$ scores) were submitted to factor analysis with varimax rotation and each factor with the highest-loading outcome measure was selected. The ${\Delta}$ scores from tests with single and multiple outcome measures were submitted for a further factor analysis with varimax rotation. Results: The statistical analysis of the multiple tests determine a factorial structure with three factors: The first factor is best represented by center of pressure (COP) path length, COP confidence area, and simple reaction time. The second factor is associated with root mean square of successive difference and useful field of view (UFOV). The third factor is represented by the single ${\Delta}$ score of subjective fatigue. Conclusion: Work-related fatigue is a multidimensional phenomenon that should be assessed by multiple tests. Based on data structure and practicability, we recommend carrying out further studies to assess work-related fatigue with manual reaction time and UFOV Subtest 2.

Effects of Chloride and Sulfate Ions on Corrosion Behaviors of Structural Materials Based on Design of Experiment (실험계획에 기반한 수돗물 성분(Chloride and Sulfate Ions)의 구조재료 부식 영향성 고찰)

  • Dong-In Lim;Heng-Su Noh;Hyeok-Jun Kwon;Sung-Ryul Park;Man-Sik Jo;Doo-Youl Lee
    • Corrosion Science and Technology
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    • v.22 no.3
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    • pp.201-213
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    • 2023
  • Corrosion management of an aircraft and its engine relies on rinsing and cleaning using tap water. Few studies have reported effects of tap water species on corrosion behaviors of structural materials. In this study, a series of experiments were conducted based on the design of experiment. Solutions with different levels of chloride and sulfate ions were prepared using a full factorial design. Two structural materials (aluminum alloy and steel) were used for an alternate immersion test. Weight loss was then measured. In addition, a silver specimen was utilized as a sensor for chloride deposition measurement. The silver specimen was examined using the electrochemical reduction method, XPS, and SEM-EDS. Surface analysis revealed that levels of chloride and sulfate ions were sufficient for the formation of silver chloride and silver surface. Statistical analysis of weight loss and chloride deposition rate showed significant differences in measured values. Concentration of chloride ions greatly affected corrosion behaviors of structural materials. Sulfate ion hindered the adsorption reaction. These results emphasize the importance of controlling ion concentration of tap water used for cleaning and rinsing an aircraft.

Genetic control of shell color variation in the Haliotis discus hannai by mating experiments (교배실험을 통한 북방전복 (Haliotis discus hannai)의 패각색 변이에 대한 유전적 지배)

  • Park, Choul Ji;Nam, Won Shik;Lee, Myeong Seok;Kang, Ji-Yun;Kim, Kyung Kil
    • The Korean Journal of Malacology
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    • v.30 no.4
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    • pp.409-413
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    • 2014
  • Purple-colored shell individuals were discovered among normal green-colored shell individuals in artificial seed of Pacific abalone, Haliotis discus hannai, reared on an ordinary type of diatom and artificial diet. In the present study, factorial mating experiments were designed to clarify the genetic control of the variant (purple type) and normal (green type) of shell color. The parental population of purple type and green type individuals were derived from a single family between a female and male of each type of coloration. The all mating families were reared in same tank for the same breed environment. The individual of 4 type families were distinguished by paternity test using microsatellite DNA. In factorial mating experiments, all individuals offspring of GG (green type female and green type male), GP (green type female and purple type male) and PG (purple type female and green type male) mating types appeared to green type. In only PP (purple type female and purple type male) mating type, all individuals offspring appeared to purple type. The results suggested that the purple shell color is controlled by recessive purple type allele and a dominant green type allele at a single locus.

Study on Optimization and Skin Permeation of PIT Nanoemulsion Containing α-Bisabolol (α-Bisabolol을 함유한 PIT Nanoemulsion의 최적화 및 피부흡수연구)

  • Kim, HuiJu;Yoon, Kyung-Sup
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.6
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    • pp.1738-1751
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    • 2020
  • The skin is divided into three parts: the epidermis, the dermis, and the subcutaneous fat, and the stratum corneum, which is located at the top of the epidermis, acts as a barrier that prevents drug delivery. Nanoemulsions are known to be effective in transdermal delivery of drugs through intercellular lipids because of their unique small particle size. In this study, phase inversion temperature (PIT) nanoemulsion containing α-bisabolol was optimized using response surface methodology (RSM) for effective skin absorption of α-bisabolol. As a preliminary experiment, the 25-2 fractional factorial design method and the 23 full factorial design method were performed. Box-Behnken design was performed based on the results of the factorial design method. The content of surfactant (6.3~12.6%), co-surfactant (5.2~7.8%) and α-bisabolol (0.5~5.0%) were used as factors, and the dependent variable was the particle size of the nanoemulsion. PIT nanoemulsion optimization was performed according to the RSM results, and as a result, the optimal nanoemulsion formulation conditions were predicted to be 10.4% surfactant content, 6.3% co-surfactant content, and 5.0% α-bisabolol content. As a result of the skin absorption test, the final skin absorption rate of the PIT nanoemulsion was 35.11±1.01%, and the final skin absorption rate of the general emulsion as a control was 28.25±1.69%, confirming that the skin absorption rate of the PIT nanoemulsion was better.

A Study on the Efficacy and Equivalence of D-antigen Quantitative Analysis through QbD6sigma Process (QbD6시그마 프로세스를 통한 D-항원 정량 시험법의 유효성과 동등성에 관한 연구)

  • Kim, Kang Hee;Hyun-jung, Kim
    • Journal of Korean Society for Quality Management
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    • v.50 no.4
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    • pp.831-842
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    • 2022
  • Purpose: This study carried out the Quality by Design (QbD)6σ process to verify the effectiveness and equivalence of the finished D-antigen quantitative test method, and compared the OFAT-based method validation and test result acceptance criteria with the Analytical Quality by Design (AQbD)-based method validation and test method. This is a study on how to reduce the risk of delay in permit change by increasing the reliability of permit data in the existing method by statistically analyzing the results. Methods: With the QbD6σ process, the effectiveness and equivalence of the D-antigen quantitative test method were verified with the data of the existing test method and the new test method. Results: Method validation tests are performed based on AQbD. Critical Method Parameters are identified through risk assessment, and single/combined actions are verified by designing and performing tests for Critical Method Parameters (analysis of variance, full factorial design method). Method validation can be effectively accomplished with the QbD6σ process. Conclusion: The use of QbD6σ can be used to achieve satisfactory results for both pharmaceutical companies and regulators by using appropriate statistical analytical methods for method validation as required by regulatory agencies.

Effect of Some Design Factors in the Front Panel on the Characteristics of a Plasma Display

  • Kim, Beong-Ju;Moon, Chelo-Hee
    • Journal of Information Display
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    • v.9 no.3
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    • pp.28-32
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    • 2008
  • Low sustained voltage $(V_s)$ and high luminous efficiency (lumen/Watts) are required for the enhanced performance of an AC PDP. Both are not realized in the same condition, however, because luminous efficiency decreases when the sustained voltage is lowered in most cases. In this study, the three design factors in the front panel of a PDP, i.e., the thickness and position of the bus electrode and the thickness of the dielectric layer, were chosen to investigate how they affect the sustained voltage and the luminous efficiency, and to find a way to optimize them. Two values were given to each of the three design factors, and experiments were done via full factorial design, i.e., with a total of eight conditions, using a 3-in.diagonal test panel. The changes in the sustained voltage and the luminous characteristics were explained in connection with the discharge characteristics of the PDP cells.

Prediction of plasma etching using genetic-algorithm controlled backpropagation neural network

  • Kim, Sung-Mo;Kim, Byung-Whan
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1305-1308
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    • 2003
  • A new technique is presented to construct a predictive model of plasma etch process. This was accomplished by combining a backpropagation neural network (BPNN) and a genetic algorithm (GA). The predictive model constructed in this way is referred to as a GA-BPNN. The GA played a role of controlling training factors simultaneously. The training factors to be optimized are the hidden neuron, training tolerance, initial weight magnitude, and two gradients of bipolar sigmoid and linear functions. Each etch response was optimized separately. The proposed scheme was evaluated with a set of experimental plasma etch data. The etch process was characterized by a $2^3$ full factorial experiment. The etch responses modeled are aluminum (A1) etch rate, silica profile angle, A1 selectivity, and dc bias. Additional test data were prepared to evaluate model appropriateness. The GA-BPNN was compared to a conventional BPNN. Compared to the BPNN, the GA-BPNN demonstrated an improvement of more than 20% for all etch responses. The improvement was significant in the case of A1 etch rate.

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The Effect of Garment Formality, Yin-Yang Level, and Body Type on Impression Formation (Part I) (아동의 의복과 체형이 인상형성에 미치는 영향(제 1 보) -국민학교 1학년 담임교사를 중심으로-)

  • 이미숙;김재숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.19 no.6
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    • pp.1017-1026
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    • 1995
  • The purpose of the study was to 1) extend the cognitive categorization theory in an attempt to explain the effect of garment formality, Yin-Yang, and body type of children on impression formation, and 2) to understand teacher's attitudes toward children's school outfits. The experimental design was a $2^3$_full factorial design by 3 independent variables. The stimuli consisted of 8 color photographs and the semantic differential response scale was used to analyze the responses of 267 teachers of elementary school. The data were analyzed by factor analysis, ANOVA, Duncan' test and content analysis. Four factors emerged to account for dimensions of first impressions. These were sociability, potency, dynamics, and cooperation. Garment formality effected on impression of cooperation dimension. Garment Yin-Yang and children's body type effected on impression of social and dynamics dimensions.

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Image Perception of Nurses' Uniforms according to Colors and Motifs (색과 문양의 감성 이미지 효과 - 간호사 복을 대상으로-)

  • 김재숙;이희승
    • The Research Journal of the Costume Culture
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    • v.12 no.3
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    • pp.379-391
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    • 2004
  • The purpose of this study was to examine the effects of uniform's color and motif on nurse's impression formation. The experimental design was 5×3×2(uniform color×motif ×perceiver's gender) factorial design with a between-subjects design. The experimental materials developed for the study were a set of stimuli and a response scale. The subjects were 738 undergraduate students of Daejon and Chungnam province. The SPSS package was used for data analysis which includes factor analysis, two-way ANOVA, Duncan's multiple range test, and Cronbach's α to measure the reliability. Results were as follows; The image or the stimulus was consisted of the 4 different dimensions(evaluation, sociability, ability, potency). All the independent variables showed some significant impression effects on selected dimensions. The motif and perceiver's gender also showed significant main effects as well as some interaction effects with the color variable on some selected impression dimension and the impression effects of the three variables in relationship to perceiving nurses' images. On a conclusion, these results supported the Gestalt theory.

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Analysis of Multivariate System Using Mahalanobis Taguchi System (Mahalanobis Taguchi System을 이용한 다변량 시스템의 해석에 관한 연구)

  • Hong, Jung-Eui;Kwon, Hong-Kyu
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.32 no.1
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    • pp.20-25
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    • 2009
  • Mahalanobis Taguchi System (MTS) is a pattern information technology, which has been used in different diagnostic applications to make quantitative decisions by constructing a multivariate measurement scale using data analytic methods without any assumption regarding statistical distribution. The MTS performs Taguchi's fractional factorial design based on the Mahahlanobis Distance (MS) as a performance metric. In this work, MTS is used for analyzing Wisconsin Breast Cancer data which has ten attributes. Ten different tests are conducted for the data to determine if the patient has cancer or not. Also, MTS is used for reducing the number of test to define the relationship between each attribute and diagnosis result. The accuracy of diagnosis is compare with two different previous research.