• The Journal of Asian Finance, Economics and Business
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• 제5권2호
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• pp.139-149
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• 2018

In the contemporary era of smart tourism, travelers face more accommodation options than ever before. The rapid expansions of alternative accommodation sector are partially owing to the growth of electronic commerce and the rise of online intermediary platforms. Online travel agencies serve as a critical distribution channel for tourism sectors, and the significance is further increased for small and micro entrepreneurs whose direct communication channels are scarce. Considering the holistic process of customer experience started with a third-party online intermediary, this study explores basic and extended attributes of small and medium-sized alternative accommodation where the comparative value is created. In order to achieve the objective, a research design was developed to synthesize the qualitative evidence. The synthesis encompasses both theoretical and practical perspectives, from a systematic review and opinions of academic professionals to an in-depth interview with an industry expert and the current practices of online travel agencies. This study suggests that the sources of value creation for alternative accommodation are not always consistent with those of the traditional. Accounting for the temporal and spatial dynamics in customer experience, the findings of this study provide insights on the comparative value of alternative accommodation, to both academic and industry audiences.

• 한국재료학회지
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• 제16권11호
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• pp.687-691
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• 2006

Synthesis of Iron oxides by air oxidation of $FeSO_4$ solutions in the presence of NaOH, Diethylenetriamine (DETA), Butylamine (BA) and influence of ultrasonic wave were investigated by XRD, SEM and particle size analyzer. As the DETA addition increased to 0.05 mol, $Fe_3O_4$ was formed with goethite($\alpha$- FeOOH) and $Fe_3O_4$ single phase was formed above 0.18mol of DETA. As the BA addition increased, the XRD peak intensity of (020) face of lepidocrocite($\gamma$-FeOOH) was developed until the formation of $Fe_3O_4$ and reduced the size of the iron oxide particles formed. Ultrasonic wave reduced the size of the iron oxide particles but gave little effects on the iron oxide particles synthesized by amine.

• 대한화장품학회지
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• 제28권1호
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• pp.71-79
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• 2002

In the aged skin especially in the face and eyelid, deep and slight wrinkles are one of the remarkable phenomena of aging and the cause of wrinkle is various. Among the cause of wrinkles an oxidative stress plays an important roles in wrinkle formation process. It caused the lipid peroxidation of cell membrane, the increase of the MMPs(MatrixMetalloProteinase) gene expression and cellular DNA damage. These ROS induced materials may cause the degradation of collagen matrix system in the dermis and cause the formation of skin wrinkle. So, it is very important for protecting skin wrinkle formation to regulate ROS activity. In this study, we developed one active ingredient having multi functional activities such as activation of collagen synthesis, inhibition of MMPs activity, lipid peroxidation and free radical scavenging activity and inhibition of free radical induced DNA damage in vitro. Pericarpium castaneae extracts showed collagen synthesis increase in Normal Human Fibroblast and the inhibition of elastase activity (IC$\_$50/ of Elastase: 43.9$\mu\textrm{g}$/㎖). It showed also anti-oxidative activity (IC$\_$50/ : 48$\mu\textrm{g}$/㎖) and free radical scavenging activity(IC$\_$50/: 7.6$\mu\textrm{g}$/㎖). Conclusively, Pericarpium castaneae extracts may be used as an ingredient for new anti-wrinkle cosmetics.

• 대한한방부인과학회지
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• 제30권2호
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• pp.37-48
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• 2017

Objectives: Artemisiae Annuae Herba is the dried aerial part of Artemisia annua L. (AAL). In Oriental medicine, Artemisiae Annuae Herba (AAH) is traditionally used to treat fever. AAH clears summerheat or damp-Heat, clears deficiency fevers, cools the blood and stops bleeding, stops malarial disorders and relieves heat, clears liver heat and brightens the eyes. Recently, there were many studies about effects of AAH on anti-oxidative, anti-inflammatory, anti-cancer, hair growth and plasma lipid composition. So, we expected AAH has an availability that can effect on skin whitening and elasticity. Methods: The present study was designed to investigate the effects of AAH on skin whitening and elasticity in SK-MEL-2 cells. In this experiment, the effects of AAH on proliferation rates, melanin synthesis, tyrosinase activities and production levels of tyrosinase, MMP-1 and MMP-9 in vitro were examined. Results: AAH did not affect viability of SK-MEL-2 cells and inhibited melanin synthesis induced by ${\alpha}$-Melanocyte-stimulating hormone (${\alpha}$-MSH) significantly. In addition, AAH also inhibited tyrosinase activity and lowered tyrosinase level in SK-MEL-2 cells. Finally, AAH inhibited productions of Matrix metalloproteinase-1 (MMP-1) and Matrix metalloproteinase-9 (MMP-9). Conclusions: These data suggest that AAH can be used to treat patients with skin diseases such as freckled face and also used as skin whitening agent.

• Journal of Microbiology and Biotechnology
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• 제25권7호
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• pp.1129-1135
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• 2015

The synthesis of gold nanoparticles has gained tremendous attention owing to their immense applications in the field of biomedical sciences. Although several chemical procedures are used for the synthesis of nanoparticles, the release of toxic and hazardous by-products restricts their use in biomedical applications. In the present investigation, gold nanoparticles were synthesized biologically using the culture filtrate of the filamentous fungus Alternaria sp. The culture filtrate of the fungus was exposed to three different concentrations of chloroaurate ions. In all cases, the gold ions were reduced to Au(0), leading to the formation of stable gold nanoparticles of variable sizes and shapes. UV-Vis spectroscopy analysis confirmed the formation of nanoparticles by reduction of Au³⁺ to Au⁰. TEM analysis revealed the presence of spherical, rod, square, pentagonal, and hexagonal morphologies for 1 mM chloroaurate solution. However, quasi-spherical and spherical nanoparticles/heart-like morphologies with size range of about 7-13 and 15-18 nm were observed for lower molar concentrations of 0.3 and 0.5 mM gold chloride solution, respectively. The XRD spectrum revealed the face-centered cubic crystals of synthesized gold nanoparticles. FT-IR spectroscopy analysis confirmed the presence of aromatic primary amines, and the additional SPR bands at 290 and 230 nm further suggested that the presence of amino acids such as tryptophan/tyrosine or phenylalanine acts as the capping agent on the synthesized mycogenic gold nanoparticles.

• 한국통신학회논문지
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• 제19권4호
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• pp.614-623
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• 1994

얼굴을 마주보며 인간끼리 대화하는 것처럼 인간과 자연스럽게 대화할 수 있는 휴먼인터페이스를 실현하기 위해서는 임성의 합성과 얼굴영상의 합성이 필요하다. 본 논문은 얼굴영상의 합성을 대상으로 한다. 얼굴영상의 합성에서는 표정변화와 입모양의 변화를 3차원적으로 실현하기 위하여 얼굴의 3차원 형상모델을 이용한다. 얼굴의 3차원 모델을 얼굴 근육의 움직임에 따라 변형하므로서 다양한 얼굴표정과 음절에 어울리는 입모양을 합성한다. 우리말에서 자모의 결합으로 조합가능한 음절은 14,364자에 이른다. 이 음절에 대한 입모양의 대부분은 모음에 따라 형성되고, 일부가 자음에 따라 달라진다. 그러므로, 음절에 어울리는 입모양의 변형규칙을 정하기 위해, 이들을 모두 조사하여 모든 음절을 대표할 수 있는 입모양패턴을 모음과 자음에 따란 분류한다. 그 결과, 자음에 영향을 받는 2개의 패턴과 모음에 의한 8개의 패턴, 총 10개의 패턴으로 입모양을 분류할 수 있었다. 나아가서, 분류된 입모양패턴의 합성규칙을 얼굴근육의 움직임을 고려하여 정한다. 이와같이 분류된 10개의 입모양패턴으로 모든 음절에 대한 입모양을 합성할 수 있고, 얼굴근육의 움직임을 이용하므로써 다양한 표정을 지으면서 말하는 자연스런 얼굴영상을 합성할 수 있었다.

• 한국음향학회지
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• 제35권2호
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• pp.134-142
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• 2016

본 논문에서는 40 kHz 초음파 신호를 입 주변에 쏘고, 되돌아오는 초음파 신호를 이용해 음성신호를 합성하는 방법을 소개하고 성능을 평가하였다. 발성하고 있는 입주변에 초음파를 방사하게 되면, 입술, 턱, 뺨 등의 움직임으로 인한 변위로 도플러 현상이 발생하고, 이에 따라 반사 신호에는 본래의 주파수 성분과는 다른 도플러 주파수가 관찰되는데, 본 논문에서는 이러한 도플러 주파수를 이용하여 음성 파라메터를 추정하도록 하였다. 음성합성에 앞서서 초음파 도플러 신호와 음성 신호 간의 상관관계를 각 주파수 별로 분석하였으며, 이로부터 초음파 도플러 신호를 이용한 음성 신호의 합성 가능성을 살펴보았다. 변환에는 초음파 도플러의 정적, 동적 특성을 함께 반영한 특징 변수를 사용하였으며 결합-혼합 가우시안 기법을 이용하여 음성 파라메터로 변환하였다. 5명의 피 실험자를 이용한 음성 합성 실험에서 필터뱅크 에너지 값을 초음파신호의 특징변수로, LPC(Linear Predictive Coefficient) 켑스트럼 계수를 음성 변수로 사용하는 경우 가장 우수한 변환 성능을 나타내었다. 음성신호에서 추출한 여기신호를 이용하여 합성음을 생성하고, 이를 청취하였을 때 72.2 %의 평균 인식율이 얻어짐을 확인할 수 있었다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권8호
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• pp.3473-3487
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• 2020

In this paper, we present a new approach to creating speech animation with emotional expressions using a small set of example models. To generate realistic facial animation, two example models called key visemes and expressions are used for lip-synchronization and facial expressions, respectively. The key visemes represent lip shapes of phonemes such as vowels and consonants while the key expressions represent basic emotions of a face. Our approach utilizes a text-to-speech (TTS) system to create a phonetic transcript for the speech animation. Based on a phonetic transcript, a sequence of speech animation is synthesized by interpolating the corresponding sequence of key visemes. Using an input parameter vector, the key expressions are blended by a method of scattered data interpolation. During the synthesizing process, an importance-based scheme is introduced to combine both lip-synchronization and facial expressions into one animation sequence in real time (over 120Hz). The proposed approach can be applied to diverse types of digital content and applications that use facial animation with high accuracy (over 90%) in speech recognition.

• 한국환경과학회지
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• 제12권1호
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• pp.77-80
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• 2003

The interaction of mastoparan B, a cationic tetradecapeptide amide isolated from the hornet Vespa basalis, with phospholipid bilayers was studied with synthetic mastoparan B and its analogue with Ala instead of hydrophobic 12th amino acid residue in mastoparan B. MP-B and its derivative, [12-Ala]MP-B were synthesized by the solid-phase peptide synthesis method. MP-B and its analogue, [12-Ala]MP-B adopted an unordered structure in buffer solution. In the presence of neutral and acidic liposomes, the peptides took an $\alpha$-helical structure. The two peptides interacted with neutral and acidic lipid bilayers. These results indicated that the hydrophobic face in the amphipathic $\alpha$-helix of MP-B critically affected the biological activity and helical content.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 추계학술대회논문집
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• pp.452-458
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• 2003

This paper presents a robust vibration control methodology of smart structural systems. The governing equations and associated boundary conditions are derived by Hamilton's principle. A robust controller is designed using a linear matrix inequality (LMI) approach to the multiobjective synthesis. The design objectives are to achieve a mix of H$\sub$$\infty$/ performance and H$_2$ performance satisfying constraints on the closed-loop pole locations in the face of model uncertainties. Numerical examples are presented to demonstrate the effectiveness of LMI approach in damping out the multiple modes of vibration of the piezo/beam system.