• Journal of Microbiology and Biotechnology
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• v.9 no.1
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• pp.113-118
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• 1999

The insulin-like growth factor (IGF) is found in all vertebrates and its type-II molecule is regarded as a fundamental embryonic growth factor during development. We have firstly identified, in this study, a cDNA clone corresponding to IGF-II (flIGF-II) from the adult brain of the teleost, Paralichthys olivaceus. We also examined the tissue expression of flIGF-II in several adult tissues by RT-PCR. The flIGF-II cDNA contained a complete ORF consisting of 215 amino acids and one stop codon. Its molecular characteristics appear to be similar to the previously identified IGF-II molecules, in which a common primary structure exhibiting B, C, A, D, and E domains is evidently observed. This cDNA clone seems to be cleaved at $Ala_{52}$ for the $NH_2$-end signal peptide and appears to produce a 98 amino acid-long E-peptide from the $Arg^{118}$. The functional B-D domain regions, therefore, include 65 amino acids and is able to encode a 7.4-kDa protein. The most prominent structural difference between IGF-I and IGF-II was that the D domain of IGF-II exhibits a two-codon-deleted pattern compared to the 8 amino acid-containing IGF-I. The insulin family signature in the A domain and six cysteins forming three disulfide bridges between the B and A domains were evolutionary-conserved from teleosts to mammalian IGF-II. Interestingly, the E-peptide region appears to provide a distinct hallmark between teleosts in amino acid composition. The flIGF-II shows 85.1% of sequence identity to salmon and trout, 90.6% to tilapia, and 98.4% to perch in amino acid level. In tissue expressions of IGF-II, it is very likely that flIGF-II has a significant expression in the adult brain. However, liver seems to be the main source for IGF-II production, and relatively low signals were observed in the adult muscle and kidney. Taken together, it would be concluded that the functional region for IGF-II mRNA is highly similar in phylogeny and is evolutionary, conserved as a mediator for the growth of vertebrates.

• 한국태양에너지학회:학술대회논문집
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• 2009.04a
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• pp.66-71
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• 2009

To reduce the building energy consumption, the major advanced nations are conducting actively many researches on so called a "self-sufficient building(or other words zero energy building)" which can support its required energy by itself. Given this background, KIER(Korea Institute of Energy Research) built full size test-bed of the zero energy solar house in early 2002, and has studied on the self-sufficient heating load up to now. We analyse the sensitivity between the heating load and the solar radiation gain according to the change the effective transmittance of windows. The authors classified 9 cases by solar transmittance of glass. The results demonstrate the solar radiation amount is 0.466 MWh from the eastern zone of Fl.,1(the first floor), 0.332 MWh from Fl.,2(the second floor), 1.194 MWh form the southern zone of F1., and 0.822 MWh from the southern zone of Fl.,2 on the case 1(each cases are classified by window types). On the case 9, the solar radiation amount is 3.127 MWh, 2.662 MWh, 8.799 MWh and 6.078 MWh from the same condition. For the Fl.,1, the amount of Heat Load that is saved per year ranged 10.5 to 48 %, and the reduction was anywhere from 0.2 to 17.9% for Fl.,2

• Fisheries and Aquatic Sciences
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• v.10 no.1
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• pp.30-36
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• 2007

We present age and growth data for Ilisha elongata, based on 363 specimens caught in 1999 and 2000 around Jeju Island and the southwest coast of Korea. Scale and ring radii of each ring group showed a direct one-to-one relationship, with ring radius increasing as scale radius increased. The relationship between fork length and scale radius was FL=39.553SR+60.935 for females, FL=39.474SR+54.026 for males, and FL=39.608SR+57.547 for both sexes. Monthly changes in the marginal index indicated that a new ring appears once each year (in July). Maximum age, mean age and mean fork length of fish were 10 years, 5.0 years, and 349mm, respectively. Von Bertalanffy's growth equations were $FL_t=495.4{\times}[1-\exp(-0.2586(t+0.6487))]$ for fork length (mm) and $W_t=1,112.5{\times}[1-\exp(-0.2586(t+0.6487))]^{2.874}$ for body weight (g) for both sexes. Monthly changes in the gonadosomatic index (GSI) indicated that the spawning period was in June and July, which corresponded closely with ring formation time. Differences in monthly GSI changes in 1999 and 2000 may be related to water temperature variation. Fecundity ranged from 5,664 to 176,290 eggs per individual (n=43, fork length 264-470mm). The relationship between fecundity(F) and fork length was $F=7.7{\times}10^{-7}{\times}FL^{4.9269}$.

• Journal of the Korean Solar Energy Society
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• v.29 no.2
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• pp.62-69
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• 2009

To reduce the building energy consumption, the major advanced nations are conducting actively many researches on so called a "self-sufficient building(or other words zero energy building)" which can support its required energy by itself. Given this background, KIER(Korea Institute of Energy Research) built full size test-bed of the zero energy solar house in early 2001, and has studied on the self-sufficient heating load up to now. We analyse the sensitivity between the heating load and the solar radiation gain according to the change the effective transmittance of windows. The authors classified 9 cases by solar transmittance of glass. The results demonstrate the solar radiation amount is 0.466 MWh from the eastern zone of Fl.,1(the first floor), 0.332 MWh from Fl.,2(the second floor), 1.194 MWh form the southern zone of F1., and 0.822 MWh from the southern zone of Fl.,2 on the case 1(each cases are classified by window types). On the case 9, the solar radiation amount is 3.127 MWh, 2.662 MWh, 8.799 MWh and 6.078 MWh from the same condition. For the Fl.,1, the amount of Heat Load that is saved per year ranged 10.5 to 48%, and the reduction was anywhere from 0.2 to 17.9% for Fl.,2.

• Journal of Digital Convergence
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• v.18 no.9
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• pp.49-56
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• 2020

This study aims to examine the effects of CF about learners' English writing through FL on English improvement and the factors that influence class satisfaction. For achieving this purpose, response to CF and feelings about CF were selected as predictive variables. It is intended to investigate how these variables predict learners' satisfaction. A total of 94 university students were placed into two groups: 48 experimental group, who received CF on their writing through FL, and 46 control group given traditional instruction. All the participants took pre/post tests including writing tasks, and the experimental group completed a questionnaire after the instructional treatment. The findings indicated that FL affected English improvement and both response to CF and feelings about CF predicted class satisfaction. Based on the findings, this study sheds light on the implications of how to manage the FL class efficiently.

• Journal of the Korean Geographical Society
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• v.44 no.3
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• pp.282-300
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• 2009

This paper attempts to focus the ways in which Seoul as an urban space can be read and interpreted from gender perspective, assuming Seoul as a cultural text which represents modernity and post-modernity. Drawing on discussions of urban sociology and human geography which have analyzed the relationship between material spaces and social subjects, this paper explores the gendered segregation and representations of space in Seoul which has been constructed through the process of modernization. The framework of spatial interpretation of Seoul, concentrating on imageablity and legibility, consists of three dimensions; gendered division of labour and sphere, dichotomy of representations along with femininity and masculinity, and the ways of interlocking between modernity and post-modernity. In this paper, 'fl$\check{a}$nerie', Benjamin's method of interpretation of urban culture and the way of seeing with 'speculum' of Irigaray are adopted as metaphoric methodologies. It is an attempt to develop a new methodology to analyze and interpret urban space from gender-cultural perspective.

• Korean Journal of Acupuncture
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• v.23 no.3
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• pp.55-71
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• 2006

Objectives : The present study was investigated the effect and pathway of heterotopic electroacupuncture (EA) on pain induced by formalin in rats. Methods : Acupoints in the right forepaws, $HT_7$ and $PC_7$, were stimulated with 3 mA, 2 ms, and 10 Hz before subcutaneously formalin injection (5%, $50{\mu}l$) to the left hind paw. Moreover, it was investigated whether the dorsolateral funiculus (DLF), as known to the descending inhibition, mediates analgesia of the heterotopic EA, and an administration of naltrexone blocks the effect of EA. Results : In the immunohistochemistry of cFos-like protein (cFL), there were inhibitory effects of EA on the increased expression of cFL in the lumbar spinal dorsal horn neurons following formalin injection. Especially, EA inhibited the expression of cFL on the superficial laminae than that on the deep laminae at 1 hr after, but that on the deep laminae than that on the superficial laminae at 2 hr after. Also, EA suppressed the increased expression of nitric oxide (NO) and neuronal nitric oxide synthase (nNOS) in the lumbosacral spinal cord after formalin injection, but not Sham-EA. Suppressed expressions of cFL, NO and nNOS in the spinal cord were eliminated after transection of the ipsilateral DLF at $T_{10}{\sim}T_{11}$ levels. However, pretreatment of naltrexone could not prevent the suppressive expressions of cFL, NO and nNOS at the spinal cord. Conclusions : These results suggest that the analgesia of heterotopic EA may be modulated through the DLF constituting the descending inhibition.

• Journal of the Korean Society of Food Culture
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• v.36 no.6
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• pp.555-562
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• 2021

This study sought to investigate the association between the food literacy (FL) of children and mothers, and the maternal feeding style. Study subjects were mothers (n=400) with children in the 4th to 6th grades of elementary school and who were the primary caregivers for their children (n=400). The responses to the Caregiver's Feeding Styles Questionnaire (CFSQ) were obtained from mothers. Both mothers and children completed the questionnaire for socio-demographics, dietary habits, health status, and food literacy. The high demanding/high responsive feeding style was associated with increased meal frequency for both mothers and children. The low demanding/low responsive feeding style was significantly associated with a lower mother's FL after accounting for confounding factors. The low demanding feeding styles were associated with the child's lower FL after adjustments for the age, sex, weight status of the child and the age, household income, and education of the mother. However, this association was not seen after making an additional adjustment for the mother's FL. These results suggest that the caregiver's feeding style may affect the dietary habits and FL of both mother and child.

• The Journal of the Korea Contents Association
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• v.19 no.5
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• pp.74-81
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• 2019

The purpose of this study is to summarize the trends and trends of the researchin on flipped learning (FL) in Korea. To accomplish this, a total of 680 papers were selected by using the RISS academic paper search function, and the content analysis was conducted based on the basic bibliographic information provided by RISS and the coding schemes derived from the process of analysis. The data were classified according to the nature of the thesis, method of research, subject of study, academic field of study, topic of research. As a result, the first academic article related to FL appeared in 2013. After the year, FL research has been increased rapidly in various fields. In terms of purpose of study, introduction of FL, basic discussion, exploratory application, and deepening and expansion of the discussion have gradually developed. Now that the challenge of quantitative growth has been fully achieved, it is proposed to examine and consolidate the theoretical foundations of FL research.

• Nuclear Engineering and Technology
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• v.54 no.1
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• pp.49-60
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• 2022

Motivated by the high-resolution properties of high-order Weighted Essentially Non-Oscillatory (WENO) and flux limiter (FL) for steep-gradient problems and the robust convergence of Jacobian-free Newton-Krylov (JFNK) methods for nonlinear systems, the preconditioned JFNK fully implicit high-order WENO and FL schemes are proposed to solve the transient two-phase two-fluid models. Specially, the second-order fully-implicit BDF2 is used for the temporal operator and then the third-order WENO schemes and various flux limiters can be adopted to discrete the spatial operator. For the sake of the generalization of the finite-difference-based preconditioning acceleration methods and the excellent convergence to solve the complicated and various operational conditions, the random vector instead of the initial condition is skillfully chosen as the solving variables to obtain better sparsity pattern or more positions of non-zero elements in this paper. Finally, the WENO_JFNK and FL_JFNK codes are developed and then the two-phase steep-gradient problem, phase appearance/disappearance problem, U-tube problem and linear advection problem are tested to analyze the convergence, computational cost and efficiency in detailed. Numerical results show that WENO_JFNK and FL_JFNK can significantly reduce numerical diffusion and obtain better solutions than traditional methods. WENO_JFNK gives more stable and accurate solutions than FL_JFNK for the test problems and the proposed finite-difference-based preconditioning acceleration methods based on the random vector can significantly improve the convergence speed and efficiency.