• 제목/요약/키워드: F.E.M

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Effects of Steroid Hormone in Avian Follicles

  • Caicedo Rivas, R.E.;Nieto, M. Paz-Calderon;Kamiyoshi, M.
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권4호
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    • pp.487-499
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    • 2016
  • The aim of the present study was to examine the effects of testosterone (T) and estradiol-$17{\beta}$ ($E_2$) on the production of progesterone ($P_4$) by granulosa cells, and of the $E_2$ on the production of $P_4$ and T by theca internal cells. In the first experiment, granulosa cells isolated from the largest ($F_1$) and third largest ($F_3$) preovulatory follicle were incubated for 4 h in short-term culture system, $P_4$ production by granulosa cells of both $F_1$ and $F_3$ was increased in a dose-dependent manner by ovine luteinizing hormone (oLH), but not T or $E_2$. In the second experiment, $F_1$ and $F_3$ granulosa cells cultured for 48 h in the developed monolayer culture system were recultured for an additional 48 h with increasing doses of various physiological active substances existing in the ovary, including T and $E_2$. Basal $P_4$ production for 48 h during 48 to 96 h of the cultured was about nine fold greater by $F_1$ granulosa cells than by $F_3$ granulosa cells. In substances examined oLH, chicken vasoactive intestinal polypeptide (cVIP) and T, but not $E_2$, stimulated in a dose-dependent manner $P_4$ production in both $F_1$ and $F_3$ granulosa cells. In addition, when the time course of $P_4$ production by $F_1$ granulosa cells in response to oLH, cVIP, T and $E_2$ was examined for 48 h during 48 to 96 h of culture, although $E_2$ had no effect on $P_4$ production by granulosa cells of $F_1$ during the period from 48 to 96 h of culture, $P_4$ production with oLH was found to be increased at 4 h of the culture, with a maximal 9.14 fold level at 6 h. By contrast, $P_4$ production with cVIP and T increased significantly (p<0.05) from 8 and 12 h of the culture, respectively, with maximal 6.50 fold response at 12 h and 6, 48 fold responses at 36 h. Furthermore, when $F_1$ granulosa cells were precultured with $E_2$ for various times before 4 h culture with oLH at 96 h of culture, the increase in $P_4$ production in response to oLH with a dose-related manner was only found at a pretreatment time of more than 12 h. In the third experiment, theca internal cells of $F_1$, $F_2$ and the largest third to fifth preovulatory follicles ($F_{3-5}$) were incubated for 4 h in short-term culture system with increasing doses of $E_2$. The production of $P_4$ and T by theca internal cells were increased with the addition of $E_2$ of $10^{-6}M$. These increases were greater in smaller follicles. These results indicate that, in granulosa cells of the hen, T may have a direct stimulatory action in the long term on $P_4$ production, and on $E_2$ in long-term action which may enhance the sensitivity to LH for $P_4$ production, and thus, in theca internal cells, $E_2$ in short term action may stimulate the production of $P_4$ and T.

솔-젤법으로 제조한 PZT박막의 유전 및 전기적 특성 (Dielectric and electric properties of sol-gel derived PZT thin Films)

  • 홍권;김병호
    • E2M - 전기 전자와 첨단 소재
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    • 제9권3호
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    • pp.251-258
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    • 1996
  • Sol-Gel derived ferroelectric Pb(Z $r_{0.52}$ $Ti_{0.48}$) $O_{3}$ thin films have been fabricated on Pt/Ti/ $SiO_{2}$/Si substrate. Two kinds of fast annealing methods, F-I (six times of intermediate and final annealing) and F-II(one final annealing after six times of intermediate annealing) were used for preparation of multi-coated PZT thin films. As the annealing temperature was increased, high capacitance could be obtained, for instance, 2700.angs.-thick PZT thin film annealed at 680.deg. C had a capacitance value of approximately 20nF at 1kHz. In addition, it is found that the dielectric constant is a function of the perovskite phase fraction. In case of F-I method, PZT thin film had a remanent polarization(Pr) of 8-15.mu.C/c $m^{2}$ and a coercive field( $E_{c}$) of 35-44kV/cm according to annealing temperature, whereas PZT film fabricated by F-II method had as high as 24-25.mu.C/c $m^{2}$ and 48-59kV/cm, respectively. As a result of measuring Curie temperature, PZT thin film had a range of 460-480.deg. C by F-I method and more or less higher range of 525-530.deg. C by F-II method, which implied that different microstructures could cause the different Curie temperature. Through I-V measurement, leakage current of PZT thin film fabricated by F-I and F-II methods was 64nA/c $m^{2}$ and 2.2.mu.A/c $m^{2}$ in the electric field of 100kV/cm, respectively.y.y.y.

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Lq-ESTIMATES OF MAXIMAL OPERATORS ON THE p-ADIC VECTOR SPACE

  • Kim, Yong-Cheol
    • 대한수학회논문집
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    • 제24권3호
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    • pp.367-379
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    • 2009
  • For a prime number p, let $\mathbb{Q}_p$ denote the p-adic field and let $\mathbb{Q}_p^d$ denote a vector space over $\mathbb{Q}_p$ which consists of all d-tuples of $\mathbb{Q}_p$. For a function f ${\in}L_{loc}^1(\mathbb{Q}_p^d)$, we define the Hardy-Littlewood maximal function of f on $\mathbb{Q}_p^d$ by $$M_pf(x)=sup\frac{1}{\gamma{\in}\mathbb{Z}|B_{\gamma}(x)|H}{\int}_{B\gamma(x)}|f(y)|dy$$, where |E|$_H$ denotes the Haar measure of a measurable subset E of $\mathbb{Q}_p^d$ and $B_\gamma(x)$ denotes the p-adic ball with center x ${\in}\;\mathbb{Q}_p^d$ and radius $p^\gamma$. If 1 < q $\leq\;\infty$, then we prove that $M_p$ is a bounded operator of $L^q(\mathbb{Q}_p^d)$ into $L^q(\mathbb{Q}_p^d)$; moreover, $M_p$ is of weak type (1, 1) on $L^1(\mathbb{Q}_p^d)$, that is to say, |{$x{\in}\mathbb{Q}_p^d:|M_pf(x)|$>$\lambda$}|$_H{\leq}\frac{p^d}{\lambda}||f||_{L^1(\mathbb{Q}_p^d)},\;\lambda$ > 0 for any f ${\in}L^1(\mathbb{Q}_p^d)$.

E. M. F.法에 依한 活性度係數의 測定과 Ion水和에 對한 考察 (The Measurements of the Activity Coefficients by E.M.F. Method and A Study of the Hydration)

  • 사공열;황정의
    • 대한화학회지
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    • 제6권2호
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    • pp.113-116
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    • 1962
  • In this study we have measured the activity coefficients of NaCl in solution by E.M.F. method, depending upon MacInnes' equation at 25 dog. The cell (electrodes) is same as MacInnes' except the cock which was designed by ourselves as figure 1.Additionally, we have calculated the hydration number of NaCl from the activity coefficients using Robinson's equation and ionic hydration number according to our new formula $\frac{n_M{^+}+0.8}{n_A{^-}-0.1}=n_{MA}$, which was mentioned our former thesis.We also have calculated the hydration number of some salts from the ionic hydration number using upper formula and have got reasonable series match with other's value.As the results of our studying, we conclude it as follow;1) Liquid junction potential depend only on the bulk concentration of the both solution.2) The formula $\frac{n_M{^+}+0.8}{{n_A{^-}}-0.1}=n_{MA}$ is reasonable one in deducing to ionic hydration number.3) From upper relation, we can calculate the hydration number of unknown salts from it's ionic hydration numbers.

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Protective Action of Ambroxol on the Oxidative Damages of Lipids Hyaluronic Acid and Collagen

  • Ji Young KOH;Yung CHO;Eun Sook HAN;Lee, Chung-Soo
    • Biomolecules & Therapeutics
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    • 제6권2호
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    • pp.111-118
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    • 1998
  • Ambroxol is thought to have antioxidant ability and some antiinflammatory effect. Effect of ambroxol on the oxidative damages of lipid, collagen and hyaluronic acid was examined. F $e_{2+}$(10 $\mu$M) and 100$\mu$Mascorbate-induced lipid peroxidation of liver microsomes was inhibited by 10 and 100$\mu$M ambroxol, 30$\mu$g/ml catalase and 10 mM DABCO but was not affected by 30$\mu$g/ml SOD and 10 mM DMSO. A 10 and 100$\mu$M ambroxol and 10 mM DABCO inhibited the peroxidative action of 10$\mu$M F $e_{3+}$, 160$\mu$M ADP and 100$\mu$M NADPH on microsomal lipids, whereas inhibitory effects of 30$\mu$g/ml SOD,30$\mu$g/ml catalase and 10 mM DMSO were not detected. The degradation of hyaluronic acid caused by 107M Fe2\\`,5007M H2O2 and 100$\mu$M ascorbate was inhibited by 10 and 100$\mu$M ambroxol,30$\mu$g/ml catalase,10 mM DMSO and 10 mM DABCO, while 30$\mu$g/ml SOD did not show any effect. The cartilage collagen degradation caused by 307$\mu$ F $e_{2+}$,500$\mu$M $H_2O$$_2$ and 200$\mu$M ascorbate was prevented by 100$\mu$M ambroxol. $H_2O$$_2$ and OH . were scavenged by ambroxol, whereas $O_2$, was not removed by it. Ambroxol (100$\mu$M) and 1 mM cysteine reduced DPPH to 1,1-diphenyl-2-picrylhydrazine. In conclusion, ambroxol may inhibit the oxidative damages of lipid, hyaluronic acid and collagen by its scavenging action on oxidants, such as OH . and probably iron-oxygen complexes and exert antioxidant ability.

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두풍(頭風)과 편두통(Migraine)에 대(對)한 동서의학적(東西醫學的) 문헌고찰(文獻考察) (The biblographical study on $T{\acute{o}}u\;f{\bar{e}}ng$ and Migraine -(Comparative study between Oriental and Western Medicine)-)

  • 오소조;정지천;이원철
    • 대한한방내과학회지
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    • 제14권1호
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    • pp.129-138
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    • 1993
  • This report on the $T{\acute{o}}u\;f{\bar{e}}ng$ and Migraine comes to conclude, through the study of the Oriental- Western medical references, as follow; 1. First, $T{\acute{o}}u\;f{\bar{e}}ng$ and Migraine had some concurrencies that both the two symptoms have appeared severe and recurrent headache and more often to the female. 2 Many of them e.g. Sensory disturbance, Vertigo, Nausea, Vomiting, Tinnitus etc. in the prodrome and main symptom of $T{\acute{o}}u\;f{\bar{e}}ng$ and Migraine were identical, especially the symptom of the $f{\bar{e}}ng\;t{\acute{a}}n\;t{\acute{o}}u\;t{\grave{o}}ng$ was similar to the prodrome of the Migraine. We could find out the semilarity of the symptoms through that Migraine is proximately set in unilateral, and $Pi{\bar{a}}nT{\acute{o}}u\;f{\bar{e}}ng$ is so called alias $B{\grave{a}}n\;bi{\bar{a}}n\;t{\acute{o}}u\;t{\grave{o}}ng$. 3. The pathogeny of $T{\acute{o}}u\;f{\bar{e}}ng$ include the case of ‘$f{\bar{e}}ng\;xi{\acute{e}}\;r{\grave{u}}\;n{\bar{a}}o$’, the patient feeling weak condition, $T{\acute{a}}n,\;T{\acute{a}}nshi,\;T{\acute{a}}nhu{\breve{o}},\;Y{\grave{u}}q{\grave{i}}$, etc. and, ‘$t{\acute{a}}n\;zhu{\grave{o}}\;sh{\grave{a}}ng\;y{\acute{a}}o$’, ‘$G{\bar{a}}n\;y{\acute{a}}ng\;hu{\grave{a}}\;f{\bar{e}}ng$’. There were variable that $F{\bar{e}}ng,\;Xu{\grave{e}},\;F{\bar{e}}ngr{\grave{a}},\;F{\bar{e}}ngx{\bar{u}},\;Xu{\grave{e}}x{\bar{u}},\;Hu{\check{o}}$ in the left, and $t{\acute{a}}n,\;R{\grave{e}},\;t{\acute{a}}nr{\grave{e}},\;Qir{\acute{a}}$ in the right partial pathogeny. It was referred $Sh{\grave{a}}o\;y{\acute{a}}ng\;j{\bar{i}}ng$, $Ju{\acute{e}}\;y{\bar{i}}n\;j{\bar{i}}ng$, $Y{\acute{a}}ng\;m{\acute{i}}ng\;j{\bar{i}}ng$, $T{\grave{a}}i\;y{\acute{a}}ng\;j{\bar{i}}ng$ in connection with the Meridian system. And otherwise the primary cause of Migraine is still unknown to us. Heredity is probably important, but the mode of transmission is uncertain. Recently, the important assumption is the vasomotor change caused by vasoconstrictors like that norepinephrine, epinephrine, and serotonin etc.

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BOUNDARY-VALUED CONDITIONAL YEH-WIENER INTEGRALS AND A KAC-FEYNMAN WIENER INTEGRAL EQUATION

  • Park, Chull;David Skoug
    • 대한수학회지
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    • 제33권4호
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    • pp.763-775
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    • 1996
  • For $Q = [0,S] \times [0,T]$ let C(Q) denote Yeh-Wiener space, i.e., the space of all real-valued continuous functions x(s,t) on Q such that x(0,t) = x(s,0) = 0 for every (s,t) in Q. Yeh [10] defined a Gaussian measure $m_y$ on C(Q) (later modified in [13]) such that as a stochastic process ${x(s,t), (s,t) \epsilon Q}$ has mean $E[x(s,t)] = \smallint_{C(Q)} x(s,t)m_y(dx) = 0$ and covariance $E[x(s,t)x(u,\upsilon)] = min{s,u} min{t,\upsilon}$. Let $C_\omega \equiv C[0,T]$ denote the standard Wiener space on [0,T] with Wiener measure $m_\omega$. Yeh [12] introduced the concept of the conditional Wiener integral of F given X, E(F$\mid$X), and for case X(x) = x(T) obtained some very useful results including a Kac-Feynman integral equation.

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PHEMT 소자 최적화에 대한 연구 (Studies on Optimization of PHEMTs)

  • 한효종;이문교;설우석;이복형;이한신;임병옥;김삼동;이진구
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 하계종합학술대회 논문집 II
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    • pp.747-750
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    • 2003
  • We have studied PHEMTs optimization by means of fabrication of PHEMTs. All PHEMTs have been fixed with a gate length of 0.1 ${\mu}{\textrm}{m}$, a gate head size of 0.75${\mu}{\textrm}{m}$, and two gate fingers. We have measured the characteristics of PHEMTs with variation of source-drain spacing, pad size, and gate width. As a result, we have found the enhanced characteristics of $I_{dss}$, $S_{21}$, $h_{21}$, $f_{T}$, $f_{max}$, and $G_{ms}$ with increasing gate width. Also, $g_{m}$ has improved with decreasing source-drain spacing, and $S_{21}$ has improved with deceasing pad size.e.e.e.e.

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유한요소법에 의한 자기회로 해석 (Analysis of magnetic circuits by F.E.M.)

  • 이기식
    • 전기의세계
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    • 제29권9호
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    • pp.599-603
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    • 1980
  • Mathematically, the Electromagnetic phenomena can be represented by the Maxwell's equations, but it is very difficult to solve these equations, especially, having complex structural boundaries. By the way, the development of a computer system made us easy to solve these kind of partial differential equations. The Finite Element Method, one of the numerical methods, is very this. This paper shows the power of F.E.M. by examining, with an example of a hollow cylinder in a uniform magnetic field which is analytically solvable, the errors and the tendency of magnetic flux lines.

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