• 제목/요약/키워드: F.E.A

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B16F10 세포에서 Quercetin과 Vitamin E, L-Ascorbic acid, 환원형 글루타치온과의 병용 투여에 의한 활성산소종 발생과 항산화 효소의 활성 변화 (Change of ROS Generation and Antioxidant Enzyme Activity of Flavonol Quercetin in the Presence of Vitamin E, L-Ascorbit acid, Reduced Glutathione on the B16F10 Murine Melanoma Cells)

  • 허정심;김안근
    • 약학회지
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    • 제47권6호
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    • pp.432-437
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    • 2003
  • It has been known that quercetin, a bioflavonoid widely distributed in fruits and vegetables as dietary-derived flavonoid and exert significant multiple biological effects such as antioxidant and anti-inflammatory, anti-tumor effects. In addition, it has been shown to have a chemoprotective role in cancer, though complex effects on signal transduction involved in cell proliferation and angiogenesis. The present study investigated whether quercetin can enhance antioxidant enzyme activity (glutathione peroxidase: GPx, superoxide dismutase: SOD, catalase: CAT) and regulate the reactive oxygen species (ROS) generation in the presence of vitamin E, L-ascorbic acid, reduced glutathione (GSH) on B16F10 murine melanoma cells. After 48h treatment of cells with quercetin in the presence of vitamin E, L-ascorbic acid, GSH, we measured the cytotoxicities by MTT assay. The cells exhibited a dose-dependent inhibition in their proliferation in the presence of vitamin E, L-ascorbic acid, GSH respectively. We also investigated the effects of antioxidant enzyme activity and ROS generation. The antioxidant enzyme activity of quercetin in the presence of vitamin E was stronger than GSH, L-ascorbic acid, the same treatments decreased ROS generation in B16F10 murine melanoma cells. Taken together, these result demonstrate that the antioxidant effect of quercetin can enhanced in the presence of vitamin E and it might plays an important role in anti-oxidative effects.

세척방법에 따른 생선회의 저장 중 품질특성 (Quality Characteristics of Sliced Raw-fish Washed by Different Methods during Storage)

  • 오승희;정유경;김수현;김순동
    • 한국식품저장유통학회지
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    • 제14권6호
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    • pp.571-577
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    • 2007
  • 여러 가지 세척제(A; 수돗물, B; 옥수, C; 0.2% chitosan-ascorbate(CA), D; 0.03 ppm 오존수, E; 1.5% 식초를 함유하는 옥수, F; 1.5%식초와 CA를 함유하는 옥수)로 세척한 넙치회와 우럭회를 $10^{\circ}C$에서 저장(DS) 및 $-20^{\circ}C$서 7일간 동결한 후 $10^{\circ}C$에서 저장(TS)하면서 저장성을 조사하였다. DS는 TS에 비하여 pH와 산도의 변화가 적었다. 저장 3일째 DS 넙치회의 경우, 대조구(A)의 총균수(log cfu/g)는 6.7로 당일 5.8에 비하여 약 1 log cycle이 증가하였으나 B는 5.50, C는 3.23, D는 4.90, E는 2.40, F는 1.77로 처리직후에 비하여 감소하거나 유지하는 경향을 나타내었으며, 감균효과는 DS와 TS 모두 F > E > D > C > B > A 순이었고 우럭회에서는 F > E > C > D > B > A 순이었다. 텍스쳐는 넙치회와 우럭회 다 같이 전반적으로 TS가 DS보다 경도와 씹힘성이 좋았다. TS에서 C가 텍스쳐에 미치는 효과는 넙치에서는 크지 않았으나 우럭에서는 비교적 양호한 결과를 나타내었다. DS의 경우, 외관은 B, C 및 D가 A보다 양호하였으며 신선한 정도도 외관과 대체적으로 유사하였다. 비린내는 A > B > F > E > D > C의 순으로 낮았다. 종합적 기호도는 넙치회와 우럭회 모두 C에서 높은 경향을 보였다. TS의 경우, 외관은 넙치회에서는 B가, 우럭회에서는 C가 양호하였다. 신선한 정도는 넙치회에서는 D > C > B > A > E > F순, 우럭회에서는 D > C > B > A > E > F순이었다. 비린내는 넙치회 우럭회 모두 D에서 가장 낮았으며, 종합적 기호도도 모두 D에서 가장 양호하였다.

INJECTIVE REPRESENTATIONS OF QUIVERS

  • Park, Sang-Won;Shin, De-Ra
    • 대한수학회논문집
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    • 제21권1호
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    • pp.37-43
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    • 2006
  • We prove that $M_1\longrightarrow^f\;M_2$ is an injective representation of a quiver $Q={\bullet}{\rightarrow}{\bullet}$ if and only if $M_1\;and\;M_2$ are injective left R-modules, $M_1\longrightarrow^f\;M_2$ is isomorphic to a direct sum of representation of the types $E_l{\rightarrow}0$ and $M_1\longrightarrow^{id}\;M_2$ where $E_l\;and\;E_2$ are injective left R-modules. Then, we generalize the result so that a representation$M_1\longrightarrow^{f_1}\;M_2\; \longrightarrow^{f_2}\;\cdots\;\longrightarrow^{f_{n-1}}\;M_n$ of a quiver $Q={\bullet}{\rightarrow}{\bullet}{\rightarrow}{\cdots}{\rightarrow}{\bullet}$ is an injective representation if and only if each $M_i$ is an injective left R-module and the representation is a direct sum of injective representations.

SS41강의 F.E.M.복합조직강에서 노치변화가 부식피로파괴에 미치는 영향 (Influence of Notch Change on Corrosion Fatigue Fracture in F.E.M. Dual phase Steel of SS41 Steel)

  • 도영민;이규천
    • 한국안전학회지
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    • 제16권2호
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    • pp.44-50
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    • 2001
  • The rotated bending fatigue test was conducted in air md in 3.5% NaCl salt solution to investigate the fatigue fracture behaviour of raw material and F.E.M dual phase steel made from raw material(SS41) by a suitable heat treatment. This study has compared the initial microcrack creation of material by tensile test with that by fatigue test. And the rotated bending test of cantilever type under the condition of 3.5% NaCl salt solution and air has investigated the corrosion fatigue fracture behaviour with the variation of stress concentration factor determined by each of notch shapes. The initial microcrack have been developed in fragile grainboundary with general corrosion occurring in raw material : in the pits built up by corrosion in F.E.M. dual phase steel because pits bring out stress concentration. It is small that the degree of decrease in corrosion fatigue life for F.E.M. dual phase steel compared with raw material because the notch sensitivity of F.E.M. dual phase steel is lower than raw material in reason of characteristics with two-phase construction.

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AN ALGEBRA WITH RIGHT IDENTITIES AND ITS ANTISYMMETRIZED ALGEBRA

  • Choi, Seul-Hee
    • 호남수학학술지
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    • 제30권2호
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    • pp.273-281
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    • 2008
  • We define the Lie-admissible algebra NW$({\mathbb{F}}[e^{A[s]},x_1,{\cdots},x_n])$ in this work. We show that the algebra and its antisymmetrized (i.e., Lie) algebra are simple. We also find all the derivations of the algebra NW$(F[e^{{\pm}x^r},x])$ and its antisymmetrized algebra W$(F[e^{{\pm}x^r},x])$ in the paper.

Some Geometric Properties of the Weak*-integral

  • Rhie, Gil-Seob;Park, Hi-Kyo
    • 충청수학회지
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    • 제3권1호
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    • pp.33-40
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    • 1990
  • We prove that if a $weak^*$-measurable function f defined on a finite measure space into a dual Banach space is separable-like, then for every measurable set E, the $weak^*$ core of f over E is the $weak^*$ convex closed hull of the $weak^*$ essential range of f over E.

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Characterization of the xaiF Gene Encoding a Novel Xylanase-activity- increasing Factor, XaiF

  • Cho, Ssang-Goo;Choi, Yong-Jin
    • Journal of Microbiology and Biotechnology
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    • 제8권4호
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    • pp.378-387
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    • 1998
  • The DNA sequence immediately following the xynA gene of Bacillus stearothermophilus 236 [about l-kb region downstream from the translational termination codon (TAA) of the xynA gene]was found to have an ability to enhance the xylanase activity of the upstream xynA gene. An 849-bp ORF was identified in the downstream region, and the ORF was confirmed to encode a novel protein of 283 amino acids designated as XaiF (xylanase-activity-increasing factor). From the nucleotide sequence of the xaiF gene, the molecular mass and pI of XaiF were deduced to be 32,006 Da and 4.46, respectively. XaiF was overproduced in the E. coli cells from the cloned xaiF gene by using the T7 expression system. The transcriptional initiation site was determined by primer extension analysis and the putative promoter and ribosome binding regions were also identified. Blast search showed that the xaiF and its protein product had no homology with any gene nor any protein reported so far. Also, in B. subtilis, the xaiF trans-activated the xylanase activity at the same rate as in E. coli. In contrast, xaiF had no activating effect on the co-expressed ${\beta}-xylosidase$ of the xylA gene derived from the same strain of B. stearothermophilus. In addition, the intracellular and extracellular fractions from the E. coli cells carrying the plasmid-borne xaiF gene did not increase the isolated xylanase activity, indicating that the protein-protein interaction between XynA and XaiF was not a causative event for the xylanase activating effect of the xaiF gene.

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IDEMPOTENCE PRESERVING MAPS ON SPACES OF TRIANGULAR MATRICES

  • Sheng, Yu-Qiu;Zheng, Bao-Dong;Zhang, Xian
    • Journal of applied mathematics & informatics
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    • 제25권1_2호
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    • pp.17-33
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    • 2007
  • Suppose F is an arbitrary field. Let ${\mid}F{\mid}$ be the number of the elements of F. Let $T_{n}(F)$ be the space of all $n{\times}n$ upper-triangular matrices over F. A map ${\Psi}\;:\;T_{n}(F)\;{\rightarrow}\;T_{n}(F)$ is said to preserve idempotence if $A-{\lambda}B$ is idempotent if and only if ${\Psi}(A)-{\lambda}{\Psi}(B)$ is idempotent for any $A,\;B\;{\in}\;T_{n}(F)$ and ${\lambda}\;{\in}\;F$. It is shown that: when the characteristic of F is not 2, ${\mid}F{\mid}\;>\;3$ and $n\;{\geq}\;3,\;{\Psi}\;:\;T_{n}(F)\;{\rightarrow}\;T_{n}(F)$ is a map preserving idempotence if and only if there exists an invertible matrix $P\;{\in}\;T_{n}(F)$ such that either ${\Phi}(A)\;=\;PAP^{-1}$ for every $A\;{\in}\;T_{n}(F)\;or\;{\Psi}(A)=PJA^{t}JP^{-1}$ for every $P\;{\in}\;T_{n}(F)$, where $J\;=\;{\sum}^{n}_{i-1}\;E_{i,n+1-i}\;and\;E_{ij}$ is the matrix with 1 in the (i,j)th entry and 0 elsewhere.

일반화된 이진 Bent 시퀀스 (Generalized Binary Bent Sequences)

  • 길강미;노종선;신동준
    • 한국통신학회논문지
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    • 제27권1A호
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    • pp.35-41
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    • 2002
  • 본 논문에서 Olsen, Scholtz, Welch가 소개한 이진 bent 시퀀스군을 일반화시켜 최적의 상관 특성과 균형 특성을 갖는 일반화된 이진 bent 시퀀스를 생성하였다. 변형된 trace 변환이 정의되고 이로부터 ${F_{2^n}}$에서 중간체 ${F_{2^e}}$로의 선형함수를 사용하였다. 여기서 e|n이다. 만일 e=1이면 새로운 방법은 기존의 이진 bent 시퀀스의 경우와 같아진다. 또한 새로운 방법이 최적의 상관 특성과 균형 특성을 갖는 간단한 이진 시퀀스군을 생성시킨다는 것을 보여주고 몇 가지 예가 주어진다.