• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제35권4호
• /
• pp.199-204
• /
• 2009

Purpose: The purpose of this study is to investigate the epithelial-mesenchymal transition (EMT) induced by Snail transcription factor and Snail-transfected in vivo tumors with histopathological features. Materials and methods: We induced in vivo xenografted tumorigenesis in the oral vestibules of nude mice by a Snail transfected HaCaT cell line and investigated morphological and immunohistochemical features in Snail expressive tumors. Results: We identified tumor masses in 14 out of 15 nude mice in the HaCaT-Snail cell inoculation group, but no tumors were present in any of the HaCaT cell inoculation group. Induced tumors showed features of poorly differentiated carcinoma with invasion to neighboring muscles and bones. The HaCaT-Snail tumors showed decreased expressions of E-cadherin and cytokeratin, but showed increased expressions of vimentin and N-cadherin. Discussion: The Snail transfected xenograft can improve productivity of malignant tumors, show various histopathological features including invasive growth, and aid in the investigation of tumor progression and the interaction with surrounding tissues.

• 대한한방부인과학회지
• /
• 제23권3호
• /
• pp.78-90
• /
• 2010

Purpose: This study was performed to evaluate the effect of Clematidis Radix extract(CB) on osteoclast differentiation and gene expression. The osteocastogenesis and gene expression were determined in RANKL-induced RAW 264.7 cell. Methods: RANKL-induced RAW 264.7 cell with Clematidis Radix extract was stained by TRAP which is expressive marker of osteoclast. The gene expression of RANK, $TNF{\alpha}$, IL-6, iNOS and Cathepsin, those are factors related to bone resorption, was estimated by using Reverse Transcription-Polymerase Chain Reaction (RT-PCR). Results: Clematidis Radix extract decreased the number of TRAP-positive multi nuclei cell, and decreased the gene expression of RANK, $TNF{\alpha}$, IL-6, iNOS and Cathepsin K in RANKL-induced RAW 264.7 cell. Conclusion: It is concluded that Clematidis Radix extract might decrease the bone resorption resulted from decrease of osteoclast differentiation and it's related gene expression.

• 한국실내디자인학회논문집
• /
• 제15권4호
• /
• pp.64-72
• /
• 2006

The purpose of this study is to interpret Korean traditional space as text on the basis of Structuralism. The process of this study is illustrated as follows: At first, this research contains basic concepts and theories of Structuralism and discusses the possibilities of typological approaches in Korean traditional space interpretation. Secondly, As typological structure of traditional space, spacial and visual expressive characteristics in traditional residential space based on traditional thoughts of Koreans formed with inherent consciousness are considered with Hjelmslev's Structuralism and Wonhyo's Whajaeng theory. Finally, This study tries conceptual analysis based on Lacan's Metaphor and Metonymy emerged from unconscious mechanisms about interpretation and induction of the traditional spacial structure for contemporary Application. Structure is a group of elements forming a covariant ensemble. From this point of view, this study validates that texts are understood when methods that bring back to the creative processes and intentions are found by Text Hermeneutics.

• 복식문화연구
• /
• 제28권5호
• /
• pp.607-620
• /
• 2020

The aim of this study is to define the new expressive techniques for multicolored clamp resist (hyuphill) dyeing, based on empirical verification on relics that are estimated to be dyed by the exchange of more than two wood blocks: a previously undiscovered technique. Clamp resist dyeing (assumed to be made by exchanging wood blocks) have uneven resist printing lines or cloudy gradation. These are reproduced as follows: first, they have uneven contour lines, particularly with the color blue. It is possible to exchange wood blocks separately on patterns with uneven resist printing lines, and it has been verified that the exchange of wood blocks makes these irregular resist printing lines. It has also been verified that exchanging the wood blocks according to the gradation (to emphasize the cubic effect on the patterns) yields clamp resist dyeing with no resist printing lines but with cloudy gradations that have accented borders. This study provides basic information that enables methods of multicolored clamp resist dyeing through wood block exchange to be deduced (something that has not been attempted for a long time). Thus, the revival of the modern Korean dyeing culture based on the conservation and perseverance of the traditional dyeing techniques can be achieved.

• 사상체질의학회지
• /
• 제28권4호
• /
• pp.330-337
• /
• 2016

Objectives The purpose of this study was to investigate whether the menstrual pain affect the Sasang constitutions questionnaire response in adult women. Methods Using a structured menstrual history questionnaire, we evaluated the degree of menstrual pain of 550 adult women who participated in this clinical trial. Based on the survey we classified them into menstrual pain group and control group. They filled out SSCQ-P (Sasang Constitution Questionnaire for Patients) and we had compared the difference in response by Sasang constitutions. From 329 women in menstrual pain group and 212 women in control group, 541 questionnaire was analyzed statistically by their constitutions. Results 7 questions in Soyangin, 11 questions in Taeeumin and 20 questions in Soeumin were statistically significant in response between menstrual pain group and control group. Conclusions Soyangin's menstrual pain shows less influence on SSCQ-P than Taeeumin and Soeumin. Taeeumin who has Taeyangin's appearances and characteristics has more menstrual pain. In Soeumin, menstrual pain may result in negative and less expressive characteristics.

• 한국어교육
• /
• 제28권4호
• /
• pp.221-244
• /
• 2017

The purpose of this study is to prepare educational contents and criteria for selecting advertisement materials by exploring the necessity of value system education in Korean culture education. Furthermore, the study aims to suggest advertisements that contain meaningful materials through the criteria among the public and commercial advertisements as of 2017. Advertisements have advantages in three aspects as they focus on current culture, cultural implications and the ease of teaching and learning. These advantages indicate the usefulness of advertisements in value education. Also, the research of Hofstede (2010), Kang (2007), and Kim et al. (2011) provide discussion regarding educational contents. Subsequently, the criteria for selecting advertisements are further developed as the main purpose of this study. The criterion are to consider the objectives of culture education, to take into account the learning situation, to find relevance between the contents of the advertisement and the contents for the value system education, and consider expressive methods of advertisements and extensibility to the activities. Next, advertisements were selected for core educational items and the list of 22 is presented according to the value system, educational contents and the criterion of the advertisements discussed in the above.

• 한국보육지원학회지
• /
• 제15권5호
• /
• pp.23-45
• /
• 2019

Objective: The purpose of this study is to identify the longitudinal reciprocal relationship between young children's vocabulary ability and physical aggression in young children. Methods: Two waves of panel data(2013/2015) from the Panel Study of Korean Children were analyzed in this study by using an adapted version of Autoregressive cross-lagged modeling. A total of 306 five-year-old and seven-year-old preschoolers, and their mothers participated in the study. Autoregressive cross-lagged modeling for multiple groups was conducted by using AMOS 24.0. Results: First, vocabulary ability and physical aggression showed stability over time. Second, young children's vocabulary ability(t) had a statistically significant effect on physical aggression(t+1). Conclusion/Implications: This study confirmed the interrelationships of young children's vocabulary ability and physical aggression by examining longitudinal data using the longitudinal analysis method. This study highlights the importance of developing interventions to support language development with aggressive children. The results of the present study can be used as a source in developing policies for aggressive children and their parents.

• 보건의료산업학회지
• /
• 제12권3호
• /
• pp.13-26
• /
• 2018

Objectives: This study investigated how Korean daily newspapers frame the present government's health insurance coverage expansion policy, Moon Jae-in Care. Methods: A contents analysis was conducted to construct news frames represented in the four Korean daily newspapers' editorials and columns on Moon Jae-in Care during from April 2017 to April 2018. News text was classified into three different layers of frames: expressive element, narrative structure, and implied values. Results: The analysis revealed that the frequency of narrative frames was as follows: health system improvement (20.8%), public burden (14.6%), opposition by doctors (14.6%), and populism (12.5%). The financial sustainability accounted for 41.7% of the value frame, followed by procedural legitimation (18.8%), and coverage expansion (16.7%). The results also revealed that reported frames were different among newspapers: Chosun Ilbo tended to report in a negative tone, while Hankyoreh shinmun and Kyunghyang shinmun used a positive tone. Conclusions: This finding suggests that there are salient framings in reports on Moon Jae-in Care. Based on the results, the government needs to present a detailed financing plan on Moon Jae-in Care in detail. I discussed another implication of media frames results.

• 사상체질의학회지
• /
• 제33권2호
• /
• pp.25-36
• /
• 2021

Objectives The aim of this study was to reveal the difference of body shape, personality, physiological characteristics between migrant Vietnam and Daejeon women using propensity matching. Methods The number of 274 Vietnamese migrant women and Daejeon city women participate in this study. We surveyed Sasang Constitution (SC) expressive factor, such Body Mass Index (BMI) using Korea Sasang Constitutional Diagnostic Questionnaire (KS-15). A Chi-square test and a T-test were used. Significant p was .05. Results The height, weight and BMI of Daejeon women was bigger than those of Vietnam(p<.001). There was significant difference in personality characteristics in 'broad mind-narrow mind'(p<.001), 'Active-Passive'(p<.001), 'Masculine-Feminine'(p=.002). There was significant differentce in physio-pathological symptom in 'digestion'(p<.001), 'urine time'(p<.001), 'feeling cold/heat'(p=.006). There was significant differentce in distribution of SC between Vietnam and Daejeon women(p=.025). Conclusions This study reveals that there is differentce in body shape, personality, physiological characteristics between Vietnam and Daejeon women. These factors might influence on SC distribution between Vietnam and Dajeon women

• 한국보육지원학회지
• /
• 제17권4호
• /
• pp.29-47
• /
• 2021

Objective: The purpose of this study was to understand the teacher's role as play supporter in a carry out play generated curriculum and develop and implement an action plan in order to indoor free play. Methods: Participants were 14 kindergartners (9 boys, 5 girls) and one teacher. Processes of planning-implementation and observation- reflection were repeated in a cyclical procedure and the 3rd action plan was conducted based on strategies to support children's play. Results: Children experienced the following: Continuing and immersive play, play filled with experiments and challenges, play to make together, attitude to enjoy novelty and respect differences, and play of trial and error. And the researcher changed the following: Be sensitive to the child's words and actions, finding the 'real interest' of children in 'waiting', acquiring the perception that 'children are the masters of play', seeing the value of learning in children's expressive play, and gain confidence in play support. Conclusion/Implications: This study suggested the need for teacher to have patience and demonstrate reflective thinking in order to support children's play.