• Title/Summary/Keyword: Exposure chamber

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Evaluation of Exposure to Indoor Volatile Organic Compounds by Utilizing Emission Characteristics and Emission Factor of Household Mosquito Repellents (가정용 모기살충제의 배출 특성 및 배출계수를 이용한 실내 휘발성 유기화합물질 노출 평가)

  • Jo, Wan-Kuen;Lee, Jong-Hyo
    • Journal of Environmental Science International
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    • v.18 no.10
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    • pp.1123-1134
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    • 2009
  • This study was designed to evaluate qualitatively and quantitatively the pollutant compositions, which were emitted from three types of mosquito repellents(MRs)(mat-, liquid-vaporized, and coil-type) by utilizing a 50-L environmental chamber. A qualitative analysis revealed that 42 compounds were detected on the gas chromatography/mass spectrometer system, and that the detection frequency depended upon chemical types. Nine of the 42 compounds exhibited a detection frequency of 100%. Four aromatic compounds(benzene, ethyl benzene, toluene, and xylene) were detected in all test MRs. The concentration equilibriums in the environmental chamber were achieved within 180 min after sample introduction. The coil-type MR represented higher chamber concentrations as compared with the mat- or liquid-vaporized-type MR, with respect to the target compounds except for naphthalene. In particular, the chamber concentrations of ethyl benzene, associated with the use of coil-type MR, were between 0.9 and $65\;mg\;m^{-3}$ whereas those of mat- and liquid-vaporized-type MRs we~e between 0.5 and $2.0\;mg\;m^{-3}$and 0.3 and $1.4\;mg\;m^{-3}$, respectively. However, naphthalene concentrations in the chamber, where a liquid-vaporized-type MR was placed, were measured as between 17.8 and $56.3\;mg\;m^{-3}$, but not detected in the chamber, where a mat- or coil-type MR was placed. The empirical model fitted well with the time-series concentrations in the environmental chamber(in most cases, determination coefficient, $R^2$ ≿ 0.9), thereby suggesting that the model was suitable for testing emissions. In regards to the target compounds except for benzene, although they were emitted from the MRs, health risk from individual exposure to them were estimated not to be significant when comparing exposure levels with no observed adverse exposure levels or lowest observed adverse exposure levels of corresponding compounds. However, it was concluded that the use of MRs could be an important indoor source as regards benzene.

Development and Validation of Reverberation Chamber Type Whole Body Exposure System fer Mobile Phone Frequency (이동전화 주파수에 대한 전자파 잔향실 형태의 전신 노출장치 개발 및 유효성 평가)

  • 정기범;고경배;도현정;백정기;정연춘;최재훈
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.3
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    • pp.291-300
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    • 2004
  • Due to the rapid growth of mobile communication services, many studies have been performed on the biological effects of EMF(Electromagnetic field) exposure. However, it is not easy to create the field uniformity in radio frequency. To overcome this difficulty, the electric field and SAR(Specific Absorption Rate) distribution is developed to measure the whole body exposure system. In this paper, we developed the whole body exposure system for in-vivo study utilizing reverberation chamber which has a high possibility of practical use by substituting previous the EMC chamber. The field uniformity in the test area of the designed reverberation chamber was satisfied by the simulation and measurement data. In animal study of the whole body exposure for a mouse, the results of FDTD simulation were compared with those of measurement to confirm SAR under the electromagnetic exposure. We analyze the electric field distribution in the interior of the reverberation chamber and treat these results in statistical manner. In the CDMA frequency band(PCS & Cellular band), an average value of the whole body SAR and local peak value for a experimental mouse were presented for various input power.

Characteristics of flow field of nose-only exposure chamber for inhalation toxicity evaluation (흡입독성평가를 위한 비부노출 챔버의 유동흐름 특성)

  • Noh, Hakjae;Bong, Choonkeun;Bong, Hakyung;Kim, Yonggu;Cho, Myunghaing;Kim, Sanghwa;Kim, Daesung
    • Particle and aerosol research
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    • v.12 no.1
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    • pp.1-9
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    • 2016
  • In this work, we evaluated the characteristics of flow field and uniformity of the nose-only exposure chambers for the inhalation toxicity test. Computational fluid dynamics (CFD) modeling was carried out to demonstrate uniformity of the nose-only exposure chambers. Because it is very important in the inhalation toxicity experiments that test materials are distributed uniformly to each holder of the chamber. The test was done with these 3 types of chamber with different form to develop inhalation toxicity evaluation system, easy-to-operate system among exposure chamber used for evaluating inhalation toxicity of environmental chemical mixtures. Through CFD interpretation, nose-only exposure chamber was made with the selection of the optimal conditions. For its evaluation, one type of fragrance was selected and measured particle size distribution of each port. The gene becoming luminous to green fluorescence was combined with GPT-SPE, a type of tGFP vector, to be inhaled to the mouse. Based on this, luminous intensity was checked. As a result, total particle number concentration of each port had average value of $3.17{\times}10^6{\sharp}/cm^3$ and range of the highest and lowest concentration value was approximately ${\pm}4.8%$. Autopsy of lung tissues of mouse showed that it had clearly better delivery of gene compared to the control group.

GENERATION OF p-DINITROBENZENE ATMOSPHERE AND METHEMOGLOBIN FORMATION IN RATS

  • Kim, Young-Chul
    • Toxicological Research
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    • v.5 no.2
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    • pp.97-104
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    • 1989
  • A new exposure system was developed to generate p-dinitrobenzene (p-DNB) containing atmosphere. A glass column was filled with small glass beads coated with the chemical. The p-DNB containing medium was heated to a temperature beyond the boiling point of p-DNB. A stream of air flow was forced to pass through the column and let it mixed with fresh air before introducing into an inhalation chamber. The concentration of p-DNB in the chamber air was measured by direct assaying the air directly and by sampling the chemical using a microfilter installed in the chamber.

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Physiological Responses of One-year-old Zelkova serrata Makino Seedlings to Ozone in Open-top Chamber (Open-top chamber 내(內)에서 오존에 폭로(暴露)시킨 1년생(年生) 느티나무(Zelkova serrata Makino) 묘목(苗木)의 생리적(生理的) 반응(反應)에 관(關)한 연구(硏究))

  • Kim, Hyun Seok;Lee, Kyung Joon
    • Journal of Korean Society of Forest Science
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    • v.84 no.4
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    • pp.424-431
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    • 1995
  • This study was conducted to evaluate resistance and physiological responses of Zelkova serrata Makino seedlings to ozone in open-top chamber. One-year-old seedlings of Zelkova serrata were planted in pots in April and grown in greenhouse until August. The plants were transferred into two out-door open-top chambers with a dimension of 2.0 m in diameter and 2.0 m in height. First chamber served as a control and was supplied with ambient air. Ozone was added to the second chamber for 5 hours per day(10.00 AM-15.00 PM) for 23 consecutive days at 0.1 ppm. Each chamber housed 70 pots. Every two, three or five days after initiation of exposure, ten pots were randomly removed from the chamber and determined for the contents of chlorophyll a, b, total chlorophyll and ${\beta}$-carotene in the leaves. Photosynthesis and dark respiration were estimated by measuring $CO_2$ absorption in a gas exchange chamber and oxygen absorption by oxygen monitoring system, respectively. Superoxide dismutase(SOD) activity in the leaves was assayed by a xanthine oxidase method. First visible injury of translucent(water-soaked looking) spots appeared on the leaves 14 days after the initial exposure, and ozone accelerated senescence of old leaves. Contents of chlorophyll a and b decreased by 17%, and 31%, respectively, in ozone treatment two days after exposure. The decrease in chlorophyll b was greater than that of chlorophyll a. Content of ${\beta}$-carotene in ozone treatment decreased by 25% two days after initiation of exposure, but the reduction was recovered with time. Photosynthesis decreased by 45%, and the respiration increased by 28% in the ozone treatment. SOD activity started to increase 4 days after beginning of exposure and increased by 285% 7 days after exposure, and decreased to the level below the control treatment with the advancement of the visible injury.

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Exposure Measurements of Co-60 Gamma rays (Co-60 감마선의 조사선량 측정)

  • Hah, Suck-Ho;Kim, Hyun-Moon
    • Journal of Radiation Protection and Research
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    • v.16 no.2
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    • pp.7-16
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    • 1991
  • Measurement of Co-60 gamma rays has been made for establishment of exposure standard and analyze it's overall uncertainties. Exposure rate determined by the charge mode method using vibrating reed amplifier with cylinderical type cavity chamber. The values of a variety of physical constants and the correction factors are evaluated. The resulting exposure rate is 690.81 R/h at the distance of 1m from the source and the related uncertainties is ${\pm}0.8%$

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Emission Estimation and Exposure to Hazardous Gaseous Pollutants Associated with Use of Air Fresheners Indoors (실내 방향제 사용에 의한 유해 가스상 오염물질 배출 산정 및 노출 평가)

  • Jo, Wan-Kuen;Shin, Seung-Ho;Kwon, Gi-Dong;Lee, Jong-Hyo
    • Environmental Analysis Health and Toxicology
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    • v.24 no.2
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    • pp.137-148
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    • 2009
  • This study quantitatively investigated the emissions of indoor air pollutants associated with the utilization of air fresheners indoors, and evaluated individual exposure to five specified indoor air pollutants, which were chosen on the basis of selection criteria. An electrically-polished stainless steel chamber (50L) was employed to achieve this purpose. Test air fresheners were selected through three steps: first, on the basis of market sales; second, on the basis on a preliminary head-space study; and lastly, on the basis of emissions of toxic compounds (benzene, ethyl benzene, limonene, toluene, and xylene). The empirical mathematical model fitted well with the time-series concentrations in the environmental chamber (in most cases, determination coefficient, $R^2{\gtrsim}$0.9), thereby suggesting that the empirical model was suitable for testing emissions. The concentration equilibrium appeared 180 min after the introduction of sample air fresheners into the chamber. Both the chamber concentrations of emission rates or factors varied greatly according to air freshener type. It is noteworthy that although benzene, ethyl benzene, toluene, and xylene were emitted from all test air fresheners, their exposure levels were not significant enough to result in any significant health risk. However, certain type of air fresheners were observed to emit significant amount of limonene, which is potentially reactive with ozone to generate secondary pollutants with oxidants such as ozone, hydroxyl radicals, and nitrogen oxides. The exposure levels to limonene associated with the utilization of three air fresheners were estimated to be 13 to 175 times higher than that of other air fresheners. This information can help consumers to select low-pollutant-emitting air fresheners.

Formaldehyde 가스 흡입에 의한 마우스의 급성독성 및 소핵 유발성에 관한 연구

  • Kim, Choong-Yong;Kim, Kyun;Shim, Jeom-Soon;Kim, Yong-Hwa;Roh, Jung-Koo
    • Toxicological Research
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    • v.7 no.1
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    • pp.61-71
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    • 1991
  • The acute and genetic effect of formaldehyde on mice through inhalation route was studied. The Riley's chamber with one stack of cage was used for the exposure and the micronucleus test was performed under unprecedently maximum exposure concentration. LC50's of formaldehyde in mice by whole body exposure for 4 hours were 105.5 ppm with 95% confidence interval of 72.6 ppm and 143.2 ppm for male, and 159.2 ppm with 95% confidence interval of 116.5 ppm and 272.7 ppm for female. Cinicial symptoms by acute exposure were salivation, lacrimation, and abnormal respiration.

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A Fabrication and Properties of Ionization Chamber Using Madium Exposure Rate (중준위 조사선량율 측정용 전리함의 설계 및 특성)

  • Woo, Hong;Kim, Sung-Hwan;Kang, Hee-Dong
    • Progress in Medical Physics
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    • v.7 no.2
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    • pp.29-40
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    • 1996
  • We had designed and made the cylindrical ionization chamber which operated above 5 mR/h. Using commercial electrometer, we investigated the characterictic of charge collection in the ion chamber. The active volume was 190.4㎤ and overall length and diameter in the chamber was 15.5cm, 5.22cm, respectively. The chamber had three electrodes(inner, central, wall electrode). And background current was 8.39${\times}$10$\^$-14/${\pm}$1.5${\times}$10$\^$-15/A to arrange the electrodes which were coaxial in chamber axis. The collection efficiency of chamber for Cs$\^$137/ was 99.7% when the opreating voltage was applied 400V. Comparing with the commertial dosimetry system, the exposure calibration constant was 4.531${\times}$19$\^$7/R/C. By normalizing to CS$\_$137/ the relative energy response of the chamber was 1.30 for Am$\_$24/, 1.05 for C0$\_$60/, respectively. When the irrarition tranversed to the chamber axis, the isotropic effect of the chamber was not considerable.

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Evaluation of Usability and Radiation Dose Measurement Using Personal Radiation Exposure Dosimeter (방사선 개인피폭선량계를 이용한 피폭선량 측정 및 유용성 평가)

  • Kang, In-Seog;Ahn, Sung-Min
    • The Journal of the Korea Contents Association
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    • v.14 no.11
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    • pp.864-870
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    • 2014
  • To propose a basis for the selection of personal dosimeters to measure radiation dose administration of radiation workers as a way to evaluate the usefulness dosimeter. For the dosimetry of the radiation workers 2012, during 1 year, 30 were radiation workers to measure personal dose. By personal exposure is measured cumulative dose, is investigated the performance of the TLD, PLD, OSLD. And comparing the measured value of each dosimeter dose and analyzed. Medical institutions, inspection work and quarterly confirmed the cumulative exposure dose of radiation workers. Using DAP and Ion-Chamber, to measure to compare TLD, PLD, OSLD dosimeter performance. A comparison of the directly through the X-ray dosimeter and The absolute value of the Ion-Chamber, OSLD more similar than in the TLD and PLD showed the dose values so the excellent ability to measure the results. Also in radiation generating area dose of radiation workers is higher than that in OSLD. Consequently, in terms of the individual exposure management OSLD is appropriated and beneficial than others.