• Title/Summary/Keyword: Experimental evaluation

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Analytical Study on Performance Evaluation of Superdetonative Mode Ram Accelerator (초폭굉 모드 램가속기의 성능해석에 대한 이론적 연구)

  • Sung, Kunmin;Jeung, In-Seuck
    • Journal of the Korean Society of Combustion
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    • v.19 no.1
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    • pp.1-10
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    • 2014
  • An analytical study on performance evaluation of superdetonative mode ram accelerator was conducted for understanding the experimental result. The quasi-one dimensional continuum, momentum, energy equations were solved under the assumption of inviscid flow. It would be noticeable that experimental result could be analytically simulated with the assumptions of inlet shockwave, temperature dependent specific heat, and additional aluminum combustion due to ablation of aluminum projectile in superdetonative operation mode. The acceleration of ram accelerator was comparable to experimental result with the consideration of the additional aluminum combustion energy by ablation of projectile. As result, the experimental result with the aluminum projectile could be affected by heat of aluminum.

Development of New Antitumor Drugs from Natural Sources , with Guida (항종양활성 Screening을 지표로 한 천연물의약품의 개발연구와 그 생약소재의 품질평가에 대하여(抗腫瘍活性スクリ-ニングを指標とした天然物醫藥品の開發硏究とその生約素材の品質評價について))

  • Takeya, Koichi
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 1993.08a
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    • pp.14-20
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    • 1993
  • We in anticancer drug development from natural resources have conceived and used a wide variety of experimental screening systems to support our efforts during the past 20 tears. Screens have been devided to address targets at the molecular, biochemical and cellular levels, both in vivo and in vitro. Screens have been essential for the experimental evaluation of the products from natural sources. In this congress, antitumor screening methods for deveol[ment of new drugs from natural sources and evaluation of their crude drugs are discussed.

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Experimental Evaluation of Far Infrared Characteristic for Bio Liquid Ceramics used in Bulding finishing Materials (액상세라믹의 원적외선 특성의 실험적평가)

  • 지철근;최태섭;장성일
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.16 no.6
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    • pp.7-12
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    • 2002
  • This paper presents the Experimental Evaluation for the physical, chemical property and Far Infrared Characteristic, the effects to the living body of liquid ceramics which was made by the a Bio ceramic(co).

Dependence Potential of Quetiapine: Behavioral Pharmacology in Rodents

  • Cha, Hye Jin;Lee, Hyun-A;Ahn, Joon-Ik;Jeon, Seol-Hee;Kim, Eun Jung;Jeong, Ho-Sang
    • Biomolecules & Therapeutics
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    • v.21 no.4
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    • pp.307-312
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    • 2013
  • Quetiapine is an atypical or second-generation antipsychotic agent and has been a subject of a series of case report and suggested to have the potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive. In this study, we examined quetiapine's dependence potential and abuse liability through animal behavioral tests using rodents to study the mechanism of quetiapine. Molecular biology techniques were also used to find out the action mechanisms of the drug. In the animal behavioral tests, quetiapine did not show any positive effect on the experimental animals in the climbing, jumping, and conditioned place preference tests. However, in the head twitch and self-administration tests, the experimental animals showed significant positive responses. In addition, the action mechanism of quetiapine was found being related to dopamine and serotonin release. These results demonstrate that quetiapine affects the neurological systems related to abuse liability and has the potential to lead psychological dependence, as well.

An Evaluation of the Streetscape According to the Change of Moving Speed -Through the Experiment of the Virtual Reality- (이동속도의 변화에 따른 가로경관의 평가 -Virtual Reality를 이용한 실험-)

  • 정재희
    • Journal of the Korean Institute of Landscape Architecture
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    • v.28 no.5
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    • pp.15-25
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    • 2000
  • The purpose of this paper is to examine the visual evaluation structure about the formal changes of streetscape by the different moving speed in two alternative control plans for the building height and the setback regulation. The virtual reality system is applied to the experimental tool. Eighty-two experimental models are made in consideration of the height and the setback of the building regulation cased by Midou-suji street in Osaka City, Japan. and ten typical models are selected by pre-experiment. Since the changes of the landscape structure consists of the height and the setback of the building, four the evaluation items are set: grade of continuity, order, openness, preference. As there are eighty-two landscape models which are too many to be applied in this experiment, ten role models are drawn out and used in this experiment. The mean difference test, discriminant analysis, and multiple linear regression methods had been used for the statistical analysis methods. The results of this study are as follows; 1) It is found out the fact of the difference evaluation structure amount experiments models. 2) From the sketch analysis and interview, it is found out difference cognition structure by the moving speed and alternatives. 3) From the discriminant and regression analysis, it is found out that the evaluation value about continuity becomes low by the moving speed change from walking speed to driving speed. We suggest that continuous experiment should be made with a variety of groups and models, and general and universal results should also be come out of the experiments above.

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FE model updating and seismic performance evaluation of a historical masonry clock tower

  • Gunaydin, Murat;Erturk, Esin;Genc, Ali Fuat;Okur, Fatih Yesevi;Altunisik, Ahmet Can;Tavsan, Cengiz
    • Earthquakes and Structures
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    • v.22 no.1
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    • pp.65-82
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    • 2022
  • This paper presents a structural performance assessment of a historical masonry clock tower both using numerical and experimental process. The numerical assessment includes developing of finite element model with considering different types of soil-structure interaction systems, identifying the numerical dynamic characteristics, finite element model updating procedure, nonlinear time-history analysis and evaluation of seismic performance level. The experimental study involves determining experimental dynamic characteristics using operational modal analysis test method. Through the numerical and experimental processes, the current structural behavior of the masonry clock tower was evaluated. The first five experimental natural frequencies were obtained within 1.479-9.991 Hz. Maximum difference between numerical and experimental natural frequencies, obtained as 20.26%, was reduced to 4.90% by means of the use of updating procedure. According to the results of the nonlinear time-history analysis, maximum displacement was calculated as 0.213 m. The maximum and minimum principal stresses were calculated as 0.20 MPa and 1.40 MPa. In terms of displacement control, the clock tower showed only controlled damage level during the applied earthquake record.

The Effect of Fibrillar Collagen on Bony Healing of Calvarial Defect in Rats (골 조직 치유과정에서 Collagen 막의 효과)

  • Kim, Jae-Bung;Lee, Jae-Mok;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.29 no.2
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    • pp.355-373
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    • 1999
  • Many researches have been reported that collagen as cellular stroma, matrix of grafting materials, mediator of agents for the purpose of promoting healing process invivo, but the responses in vivo were seen various. The goal of this experiment is to assess the effect of collagen on bony healing, through histological evaluation of implanted collagen on the calvarial defect in rats. 2-month-old Sprague-Dawley, 24 rats were used and 12 rats assigned to each group of control and test. Defect of 5mm in diameter was made on the calvarial bone with trephine bur. Following thorough saline rinse, defect of control group was left in empty and that of experimental group was filled with fibrillar collagen($COLLATAPE^{(R)}$, COLLA-TEC. INC. U.S.A.) soaked in saline. 3 rats in each group were sacrificed at 3, 7, 14, 21 days after operation respectively, and the tissue blocks were prepared for light microscope with H-E for evaluation of overall healing, with TRAP(tartrate resistant acid phosphatase) for evaluation of osteoclastic activity and with immunohistochemical staining for macrophages. The results were as follows : 1. In the control group, inflammatory responses were disappeared at day 14, but, in the experimental group inflammatory infiltrates were reduced at day 21. Thus, the experimental group showed more severe soft tissue inflammation than control group. 2. Both control and experimental group showed slight appositional growth at day 7 and gradual bony growth to 21th day. But, complete bony healing of the defect was not shown. There was no significant difference in bony healing between control and experimental group 3. Specific response of macrophages for implanted collagen was observed at day 14 in the experimental group. In conclusion, although fibrillar collagen caused inflammation of soft tissue during initial healing period, inflammatory responses by fibrillar collagen didn't inhibit bony regeneration and implanted collagen was biodegradaded by macrophages. Thus, we expect that fibrillar collagen can be used for useful mediator of graft materials or growth factors.

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Experimental Performance Evaluation of Token-Passing Mechanism in Foundation Fieldbus (Foundation Fieldbus에서 토큰-패싱 전송 방식의 실험적 성능 평가)

  • Bae, Jin-Woon;Hong, Seung-Ho
    • Proceedings of the KIEE Conference
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    • 2006.10c
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    • pp.111-113
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    • 2006
  • FOUNDATION fieldbus provides scheduling and token-passing services for cyclic and sporadic data respectively. In this paper, we evaluate the delay performance of token-passing mechanism in FOUNDATION fieldbus network system using an experimental model. This paper introduces a method of developing an experimental model which consists of 10 nodes of FOUNDATION fieldbus communication device. Using the experimental model, we evaluate the delay performance of time-critical and time-available data with respect to change of TTRT parameter.

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Validity Analysis of Scale Model Experiment for Wetting Agent Performance Evaluation (침윤소화약제 성능평가를 위한 축소실험의 타당성 분석)

  • Kim, Nam-Kyun;Lim, Kyung-Bum;Rie, Dong-Ho
    • Fire Science and Engineering
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    • v.28 no.2
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    • pp.14-19
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    • 2014
  • A current standard exist only on the surface tension in the current domestic wetting agent technology standards, so it is difficult to the performance evaluation of the wetting agent through the standard. So this study presents the optimized performance evaluation methods by scale model experimental equipment in order to present techniques for performance evaluation of wetting agents. The purpose of this study is to investigate validity of experimental results of the self-designed scale model experiment equipment by a comparative analysis of experimental results of the NFPA 18 experiment and the experiment using the self-designed scale model experiment equipment. As a result of a comparative analysis of experimental results of the NFPA 18 experiment that evaluate only the permeation performance on the contton and the experiment using the self-designed scale model experiment equipment that evaluate the permeation performance and fire extinguishing performance on wood flour, the discrimination of the permeation performance was confirmed in both the NFPA 18 experiment and the self-designed scale model experiment equipment. And a result of self-designed experiment equipment have clear discriminatory more than NFPA 18 by internal temperature measurement using the thermocouples.