• Biomolecules & Therapeutics
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• 제22권6호
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• pp.558-562
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• 2014

Tramadol is an opioid analgesic agent that has been the subject of a series of case reports suggesting potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive in Korea. In this study, we examined the dependence potential and abuse liability of tramadol as well as its effect on the dopaminergic and serotonergic systems in rodents. In animal behavioral tests, tramadol did not show any positive effects on the experimental animals in climbing, jumping, and head twitch tests. However, in the conditioned place preference and self-administration tests, the experimental animals showed significant positive responses. Taken together, tramadol affected the neurological systems related to abuse liability and has the potential to lead psychological dependence.

• 한국생산제조학회지
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• 제26권4호
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• pp.436-440
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• 2017

This study evaluated the design and structural integrity of a three-axle bogie frame in a railway freight car through a numerical analysis and an experimental evaluation. A three-axle bogie frame, which supports the weight of the car body and load, is required to transport heavier cargo because two-axle vehicles have structural limitations. Therefore, this study performed a structural analysis and static load tests to evaluate the design and structural integrity of a three-axle bogie frame. The results obtained from the numerical analysis were compared to those of the experiments. For the bogie frame used in the experiments, a failure evaluation was performed using non-destructive methods. The numerical analysis and experimental evaluation were satisfactory for the structural integrity evaluation.

• Journal of Power Electronics
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• 제17권2호
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• pp.501-513
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• 2017

The fundamental small-signal modeling of lithium-ion (Li-ion) batteries and a parameter evaluation approach are investigated in this study to describe the dynamic behaviors of small signals accurately. The main contributions of the study are as follows. 1) The operational principle of the small signals of Li-ion batteries is revealed to prove that the sinusoidal voltage response of a Li-ion battery is a result of a sinusoidal current stimulation of an AC small signals. 2) Three small-signal measurement conditions, namely stability, causality, and linearity, are proved mathematically proven to ensure the validity of the frequency response of the experimental data. 3) Based on the internal structure and electrochemical operational mechanism of the battery, an AC small-signal model is established to depict its dynamic behaviors. 4) A classical least-squares curve fitting for experimental data, referred as Levy's method, are introduced and developed to identify small-signal model parameters. Experimental and simulation results show that the measured frequency response data fit well within reading accuracy of the simulated results; moreover, the small-signal parameters identified by Levy's method are remarkably close to the measured parameters. Although the fundamental and parameter evaluation approaches are discussed for Li-ion batteries, they are expected to be applicable for other batteries.

• Plant Resources
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• 제1권1호
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• pp.26-32
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• 1998

This paper describes the variations in eight agronomic traits in three unadapted local landraces and an inbred cultivar of corn. To compare the agronomic traits in field evaluation with molecular marker evaluation the genotypes of the plant introduction were also checked by 4 microsatellite-SSR loci. The variations of the eight agronomic traits were higher in the local landrades than in the inbred line. which was substantiated by the high genetic variation in the landrades with microsatellite-SSR loci. The level of genetic variation was also different between landraces. Since the genetic evaluation can be easily quantified by the analysis of microsatellite-SSR loci. the threshold level of genetic homogeneity in the population for parental lines in breeding program can be determined and the effort of maintaining the landrace population would be alleviated. As an example in our analysis. the entry from Whachon should not need the same number of selfing generations as the other two landraces to get the level of inbred state. Since this line showed lowest intra-genetic variation within the population.

• 간호행정학회지
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• 제9권1호
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• pp.89-101
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• 2003

Purpose : this study was to examine the effect of using a nursing standards for the quality of nursing care in musculo-skeletal patients. Method : The approach to nursing quality assurance evaluation was selected process-outcome framework. The subjects ware 100 case of musculo-skeletal patients in orthopedic surgery nursing care unit of E. university hospital in seoul. The data of a control group were collected from 23 December 2001 to 20 March 2002 and an experimental group were collected from 1 June to 25 August 2002. The instruments used for this study were a nursing care standards in musculo-skeletal disorder patients developed by the investigator and an evaluation tool for the quality of nursing care in orthopedic surgery patients developed by soon-ook Choi in 1995. It's reliability is Cronbach alpha=.8628. The data were analyzed by means of $x^1$-test, t-test, ANOVA with SPSS program. Results : This study are as fellows : 1. Scores of the quality of nursing care in standard 1 in the experimental group were higher than those of the control group with no significant difference(t=-8.793, p=.000), scores of the quality of nursing care in standard 2 in the experimental group were higher than those of the control group with significant difference(t=-8.793, p=.000) and standard 3 in the experimental group were higher than those of the control group with significant difference(t=-10.550, p=.000). scores of the quality of nursing care in standard 4 in the experimental group were higher than those of the control group with significant difference(t=-8.793, p=.000). scores of the quality of nursing care in standard 4 in the experimental group were higher than those of the control group with no significant difference(t=-1.833, p=.070). 2. Scores of the quality of nursing care in criteria 28 of 33 criteria in the experimental group were higher than those of the control group with significant difference in 12 criteria(p<.05 ). 3. Scores of the quality of nursing care in standard 1 to standard 4(process evaluation); the experimental group were higher than those of the control group with significant difference(t=-10.704, p=.000). scores of the quality of nursing care in standard 5(outcome evaluation); the experimental group were higher than those of the control group. but no significant difference(t=-1.833, p=.070). 4. Scores of the quality of nursing care in experimental group were higher than those of the control group with significant difference(t=-10.794, p=.000). Conclusion : Through this study, I'm sure that using a nursing care standards in musculo-skeletal disorder patients improve quality of nursing care and nursing care standards are effective nursing care.

• Structural Engineering and Mechanics
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• 제69권6호
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• pp.677-691
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• 2019

In recent years, interest is growing in the engineering community on the experimental assessment and the theoretical prediction of the out-of-plane (OOP) seismic response of unreinforced masonry (URM) infills, which are widespread in Reinforced Concrete (RC) buildings in Europe and in the Mediterranean area. In the literature, some mechanical-based models for the prediction of the entire OOP force-displacement response have been formulated and proposed. However, the small number of experimental tests currently available has not allowed, up to current times, a robust and reliable evaluation of the predictive capacity of such response models. To enrich the currently available experimental database, six pure OOP tests on URM infills in RC frames were carried out at the Department of Structures for Engineering and Architecture of the University of Naples Federico II. Test specimens were built with the same materials and were different only for the thickness of the infill walls and for the number of their edges mortared to the confining elements of the RC frames. In this paper, the results of these experimental tests are briefly recalled. The main aim of this study is comparing the experimental response of test specimens with the prediction of mechanical models presented in the literature, in order to assess their effectiveness and contribute to the definition of a robust and reliable model for the evaluation of the OOP seismic response of URM infill walls.

• 대한가정학회지
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• 제41권5호
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• pp.41-58
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• 2003

The purpose of this study is to develop and evaluate a social competence enrichment program for institutionalized children in early childhood. The program was developed to enhance institutionalized children's social competence. The program consists of sixteen 30-minute sessions. 19 institutionalized children (11 boys and 8 girls) participated in this program. The effect of this program was evaluated by institutionalized preschool children's emotional knowledge and interpersonal problem solving strategy. Assessment of emotional knowledge consists of identification and situation task. Interpersonal problem solving strategy includes forceful, prosocial, and manipulative strategy. Results showed that there was a significant experimental effect for emotional knowledge. Experimental children showed higher scores of emotional knowledge than control children. Also, there was a significant experimental effect for prosocial and forceful strategy. Experimental children showed higher ratio of prosocial strategy and lower ratio of forceful strategy than control children. The results of program evaluation revealed that this program was helpful for promoting institutionalized children's social competence.

• 한국생활과학회지
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• 제20권3호
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• pp.583-594
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• 2011

The purpose of this study is to develop and evaluate a climate change education program for children in early childhood. The program was developed to enhance young children's ability to prepare for climate change. The program consists of 15 30-minute sessions. 38 5-year-olds (23 boys and 15 girls) participated in this program. The effects of this program were evaluated by the pre-school children's knowledge and problem solving abilities preventing climate change. Results showed that there was a significant experimental effect for knowledge of how to prevent climate change. Experimental group showed more knowledge than the control group. Also, there was a significant experimental effect on the problem solving abilities for preventing climate change. The experimental group showed greater problem solving abilities than the control group. The results of program evaluation revealed that this program was helpful for preparing young children for climate change.

• 제어로봇시스템학회논문지
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• 제6권11호
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• pp.943-954
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• 2000

Fieldbus is the lowest level industrial network in the communication hierarchy of factory automation and distributed process control systems. Data generated from field devices are largely divided into three categories : time-critical, periodic and time-available data. Because these data share one fieldbus medium, it needs a method that allocates these data to the bandwidth-limited fieldbus medium. This paper introduces an implementation method of bandwidth allocation scheme on PROFIBUS. In order to implement bandwidth allocation scheme on PROFIBUS, the following functions need to be supplemented on the FDL(Fieldbus Datalink Layer) protocol: (i) separation of medium bandwidth into periodic and non-periodic intervals, (ii) synchronization of node timers over a local link. In order to examine the validity of bandwidth allocation scheme on PROFIBUS, this paper develops an experimental model of a network system. The results obtained from the experimental model show that the bandwidth allocation scheme satisfies the performance requirement of time-critical, periodic and time-available data.

• 한국가시화정보학회지
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• 제4권2호
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• pp.37-43
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• 2006

An experimental apparatus for PIV performance evaluation has been developed. Stardard uncertainty of a two-dimensional cross-correlation PIV system was investigated based upon the standard experimental apparatus, which was devised to model the rigid body rotating flows. For the systematic analysis of the uncertainty introduced by each component (algorithm, CCD camera, frame grabber) of the PIV system, standard images are fed into the component independently. The standard experiments show that 53% of the uncertainty in the present PIV system results from the frame grabber but the errors from the algorithm and digital camera are ignorable.