• 한국실내디자인학회논문집
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• 제20권1호
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• pp.33-42
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• 2011

This study, by applying the experiential and psychological thought category of "impression" as the space design strategy for drawing out "sensitivity," aims to break down the psychological mechanism forming the image held by the subject, and based on such segmentation, seek and strategize an effective design methodology. The subject's memory, pure sensation, and movement sensation are set as the preceding determinants comprising the psychological mechanism of space impression. The control determinants for achieving activation of psychological effect are reinterpreted as the relations of memory-cognition, sensation-perception, and movement-sensation and categorized into a cognitive strategy based on association, metaphor and remembrance; a direct sensation strategy based on formation, superposition and transposition of sensation; and a sensation strategy of process-formation based on expectation organization and reversal, contraction and relaxation. Each strategy is achieved through the formal, material and structural control of architecture. As a restructuring of the design methodology that has been experientially applied, the strategy categorization is important in that, by presenting the usefulness and effect by strategy according to space experience, it makes concrete the basic data that are useful for designing experience of sensitivity.

• 한국지능시스템학회논문지
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• 제14권5호
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• pp.610-616
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• 2004

생체 공학이나 신경생리학, 로봇공학에서는 인간의 2족 보행 메커니즘을 알아내는 것이 중요한 연구과제이며 그에 대한 연구 성과는 재활도구나 컴퓨터 애니메이션 및 인간형 로봇과 같은 다양한 응용분야에 있어서의 기초 기술로서 제공되어질 것을 기대하고 있다. 반면에 인간의 2보행 운동은 신경계와 역학계에 의한 복잡한 상호작용으로, 그 실현 메커니즘에 있어 신경계의 구체적인 제어방법에 관해서는 그 복잡성 때문에 아직 많은 부분이 불명확하게 남겨져 있다. 따라서 전문가에 의한, 매번 시행착오를 통해 신경계의 상세한 설계를 할 필요가 있다. 이 논문은 유전자 프로그래밍을 이용하여 신경계의 구조와 Parameter를 자동적으로 최적화하는 모델을 제안하고 시뮬레이션을 통해 타당성을 확인하였다.

• Genomics & Informatics
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• 제6권1호
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• pp.44-49
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• 2008

Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to extracellular stimuli involved in proliferation, differentiation and apoptosis. Comparative analysis of the PKC-${\alpha},{\beta},{\varepsilon}$ isozymes of 200 recently sequenced microbial genomes was carried out using variety of bioinformatics tools. Diversity and evolution of PKC was determined by sequence alignment. The ser/thr protein kinases of Streptomyces coelicolor A3 (2), is the only bacteria to show sequence alignment score greater than 30% with all the three PKC isotypes in the sequence alignment. S.coelicolor is the subject of our interest because it is notable for the production of pharmaceutically useful compounds including anti-tumor agents, immunosupressants and over two-thirds of all natural antibiotics currently available. The comparative analysis of three human isotypes of PKC and Serine/threonine protein kinase of S.coelicolor was carried out and possible mechanism of action of PKC was derived. Our analysis indicates that Serine/ threonine protein kinase from S. coelicolor can be a good candidate for potent anti-tumor agent. The presence of three representative isotypes of the PKC super family in this organism helps us to understand the mechanism of PKC from evolutionary perspective.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권12호
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• pp.5972-5989
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• 2019

With the onset of the big data age, data is growing exponentially, and the issue of how to optimize large-scale data processing is especially significant. Large-scale global optimization (LSGO) is a research topic with great interest in academia and industry. Spark is a popular cloud computing framework that can cluster large-scale data, and it can effectively support the functions of iterative calculation through resilient distributed datasets (RDD). In this paper, we propose a hybrid mechanism of particle swarm optimization (PSO) and differential evolution (DE) algorithms based on Spark (SparkPSODE). The SparkPSODE algorithm is a parallel algorithm, in which the RDD and island models are employed. The island model is used to divide the global population into several subpopulations, which are applied to reduce the computational time by corresponding to RDD's partitions. To preserve population diversity and avoid premature convergence, the evolutionary strategy of DE is integrated into SparkPSODE. Finally, SparkPSODE is conducted on a set of benchmark problems on LSGO and show that, in comparison with several algorithms, the proposed SparkPSODE algorithm obtains better optimization performance through experimental results.

• 천문학논총
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• 제27권4호
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• pp.289-290
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• 2012

Feedback from accreting BH (AGN) is thought to be responsible for the co-evolution of BHs and galaxies. It is likely to be prominent in the most luminous dust-obscured quasars, particularly those containing radio sources too luminous to be powered by starbursts. In order to investigate the feedback mechanism in detail, we select a unique sample containing ~ 200 of the most luminous obscured QSOs by cross-matching the WISE catalog with the FIRST and NVSS radio surveys. We present overall statistics for the observed range of colors and radio/mid-IR flux density ratio. We also present our efforts to understand the physical and evolutionary nature of these extreme feedback candidates using various telescopes such as Magellan, SOAR, Herschel, and ALMA.

• BMB Reports
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• 제50권12호
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• pp.597-598
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• 2017

Mitochondria have evolutionarily, functionally and structurally distinct outer- (OMM) and inner-membranes (IMM). Thus, mitochondrial morphology is controlled by independent but coordinated activity of fission and fusion of the OMM and IMM. Constriction and division of the OMM are mediated by endocytosis-like machineries, which include dynamin-related protein 1 with additional cytosolic vesicle scissoring machineries such as actin filament and Dynamin 2. However, structural alteration of the IMM during mitochondrial division has been poorly understood. Recently, we found that the IMM and the inner compartments undergo transient and reversible constriction prior to the OMM division, which we termed CoMIC, ${\underline{C}}onstriction$ ${\underline{o}}f$ ${\underline{M}}itochondrial$ ${\underline{I}}nner$ ${\underline{C}}ompartment$. In this short review, we further discuss the evolutionary perspective and the regulatory mechanism of CoMIC during mitochondrial division.

• Journal of Plant Biotechnology
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• 제44권1호
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• pp.1-11
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• 2017

Evolutionary studies conducted on NAC (NAM, ATAF1&2, and CUC2) genes for all major groups of land plants, indicate the presence of the NAC subfamilies, even in the early land plants. The varied roles played by NAC proteins in plant growth and development range from the formation of shoot apical meristem, floral organ development, reproduction, lateral shoot development, and defense responses to biotic and abiotic stresses. Considering the value and importance of solanaceous crops, the study of NAC proteins in these plants needs to be intensified. This will help to identify and functionally characterize their promoters, which will subsequently aid in engineering plants with improved performance under stressful conditions. In this review, the functionally characterized NAC transcription factors specific to tomato, potato, tobacco, chili pepper and eggplant (aubergine) are summarized, clearly indicating their biological functions in the defense mechanism of the plants, against biotic and abiotic stresses.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.13-13
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• 2003

When plants are infected by plant pathogens, rapid cell responses are initiated for further inhibition from fast invasion of pathogens. Hypersensitive response (HR) of plant is well known defense response stopping pathogenesis process through rapid cell death. However, informations on the signaling pathway from reception of pathogen by host plants to appropriate resistant responses are very limited to date. Efficient perception of infection by pathogens and well-programmed signalling mechanism for appropriate responses are important for survival of plants. Plant have developed a sophisticated network(s) of defense/stress responses, among which one of the earliest signalling pathways after perception (of stimuli) is the evolutionary conserved Rop GTPase and mitogen-activated protein kinase (MAPK) cascade.(중략)

• ETRI Journal
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• 제30권6호
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• pp.799-806
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• 2008

In this paper, a new design for an error correcting code (ECC) is proposed. The design is aimed to build an ECC circuitry with minimal power consumption. The genetic algorithm equipped with the symbiotic mechanism is used to design a power-efficient ECC which provides single-error correction and double-error detection (SEC-DED). We formulate the selection of the parity check matrix into a collection of individual and specialized optimization problems and propose a symbiotic evolution method to search for an ECC with minimal power consumption. Finally, we conduct simulations to demonstrate the effectiveness of the proposed method.

• 환경생물
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• 제22권4호
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• pp.479-486
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• 2004

Phytoestrogens display estrogen-like activity because of their structural similarity to human estrogens and exhibit high affinity binding for the estrogen receptors (ERs). The prevalence of phytoestrogens in our diets and the biological effects that they may cause need to be fully examined. ER is the ancestral receptor from which all other steroid receptors have evolved. Although phytoestrogens serve specific signaling functions between the plants and insects, fungi, and bacteria, many chemical signals are often misinterpreted as estrogenic signals in non-target organisms such as vertebrates. There are no ERs in plants or in their most common partners, insects. However, Rhizobium soil bacteria have NodD proteins which is an intended target of phytoestrogen signaling and share genetic homology with the ER. These two evolutionarily distant receptors both recognize and respond to a shared group of chemical signals and ligands, including both agonists and antagonists. This review briefly summarizes estrogen and estrogen receptors, kinds of important phytoestrogens, their health effects as well as some of the evolutionary aspects of mechanism by which phytoestrogen mimics the endogenous ER signaling in our body.