• Title/Summary/Keyword: Evolution of Life

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The Effect of Fretting Wear on Fatigue Crack Initiation Site of Press-fitted Shaft (압입축에 발생하는 프레팅 마모가 피로균열 발생 위치에 미치는 영향)

  • Lee, Dong-Hyong;Kwon, Seok-Jin;Choi, Jae-Boong;Kim, Young-Jin
    • Journal of the Korean Society for Railway
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    • v.10 no.5
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    • pp.546-553
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    • 2007
  • The objective of the present paper is to evaluate the effect of the evolution of contact surface profile by fretting wear on the contact stress distribution and fatigue crack initiation site of press-fitted shaft by means of an analytical method based on experimental data. A finite element analysis was performed to analyze the stress states of press-fitted shaft, considering the worn contact surface profiles of shaft. The evolutions of contact stress as wearing of contact surface were analyzed by finite element analysis and fatigue crack nucleation sites were evaluated by fretting fatigue damage parameter (FFDP) md multiaxial fatigue criteria. It is found that the stress concentration of a contact edge in press-fitted sha손 decreases rapidly at the initial stage of total fatigue life, and its location shifts from the contact edge to the inside due to fretting wear as increasing of fatigue cycles. Thus the transition of crack nucleation position in press-fitted shaft is mainly caused by stress change of a contact edge due to the evolution of contact surface profile by fretting wear. Therefore, it is suggested that the nucleation of multiple cracks on fretted surface of press fits is strongly related to the evolution of surface profile at the initial stage of total fatigue life.

Fatigue life evolution of steel wire considering corrosion-fatigue coupling effect: Analytical model and application

  • Yang Ding;Xiao-Wei Ye;Hong Zhang;Xue-Song Zhang
    • Steel and Composite Structures
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    • v.50 no.3
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    • pp.363-374
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    • 2024
  • The fatigue life of steel wire is affected not only by fatigue load, but also by corrosion environment in service period. Specially, the corrosion pit will lead to stress concentration on the surface of steel wire inducing the formation of fatigue cracks, and the fatigue cracks will accelerate the corrosion process. Therefore, the corrosion fatigue of steel wire is a coupling effect. In this study, the corrosion-fatigue coupling life curve is derived with considering corrosion-fatigue pitting stage, corrosion-fatigue short crack stage and corrosion-fatigue long crack stage. In addition, the stress concentration factors of different corrosion pits are calculated by COMSOL software. Furthermore, the effect of corrosion environment factors, that is, corrosion rate, corrosion pit morphology, frequency and action factor of fatigue load, on fatigue life of steel wire is analyzed. And then, the corrosion-fatigue coupling life curve is compared with the fatigue life curve and fatigue life curve with pre-corrosion. The result showed that the anti-fatigue performance of the steel wire with considering corrosion-fatigue coupling is 68.08% and 41.79% lower than fatigue life curve and fatigue life curve with pre-corrosion. Therefore, the corrosion-fatigue coupling effect should be considered in the design of steel wire.

Alu sequences and molecular features (Alu 서열과 분자생물학적 특징)

  • Park Eun-Sil;Hong Kyung-Won;Kim Heui-Soo
    • Journal of Life Science
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    • v.14 no.6 s.67
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    • pp.1028-1039
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    • 2004
  • During the past 65 million years, Alu sequences have been amplified through RNA-polymerase IIIderived transcripts, and have reached the copy number of about 1.4 million in primate genomes. They are the largest family among mobile genetic elements in human genome and consist of ten percent of the human genome. Alu sequences are thought to be functionless genetically, but many researchers have proved new function and disease implication. Alu elements make the genome insertional mutation, Alu-mediated recombination events, and unexpected splicing site and change gene structures, protein sequences, splicing motifs and expression patterns. In this review, the structure and origin of Alu, consensus sequences of Alu subfamilies, evolution and distribution of Alu, and their related diseases were described. We also indicated new research direction of Alu elements in relation to evolution and disease.

Evolution of Plant RNA Viruses and Mechanisms in Overcoming Plant Resistance (식물 RNA 바이러스의 진화와 병저항성 극복 기작)

  • Kim, Myung-Hwi;Kwon, Sun-Jung;Seo, Jang-Kyun
    • Research in Plant Disease
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    • v.27 no.4
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    • pp.137-148
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    • 2021
  • Plant RNA viruses are one of the most destructive pathogens that cause a significant loss in crop production worldwide. They have evolved with high genetic diversity and adaptability due to the short replication cycle and high mutation rate during genome replication, which are characteristics of RNA viruses. Plant RNA viruses exist as quasispecies with high genetic diversity; thereby, a rapid population transition with new fitness can occur due to selective pressure resulting from environmental changes. Plant resistance can act as selective pressure and affect the fitness of the virus, which may lead to the emergence of resistance-breaking variants. In this paper, we introduced the evolutionary perspectives of plant RNA viruses and the driving forces in their evolution. Based on this, we discussed the mechanism of the emergence of variant viruses that overcome plant resistance. In addition, strategies for deploying plant resistance to viral diseases and improving resistance durability were discussed.

Improvement of Photoheterotrophic $H_2$ production of Rhodobacter sphaeroides by Removing Ammonium Ion Effect Exerted on Nitrogenase (Rhodobacter sphaeroides의 질소고정효소에 미치는 암모니움 이온 효과 제거를 통한 수소생성 증진)

  • Jin, Sang-Hoon;Kim, Mi-Sun;Lee, Jeong-Kug
    • KSBB Journal
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    • v.20 no.6
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    • pp.418-424
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    • 2005
  • Photoheterotrophic evolution of molecular hydrogen by Rhodobacter sphaeroides is mediated by nitrogenase that is regulated transcriptionally and post-translationally by ammonium ion. Two PII-like proteins, GlnB and GlnK, play key roles in mediating inhibition and repression of nitrogenase in the presence of ammonium ion. glnB and glnK of R. sphaeroides were interrupted to abolish the ammonium ion effect controlling nitrogenase. Ammonium ion effect was still observed in mutant having an interruption in either glnB or glnK. However, the nitrogenase activity of glnB-glnK double mutant is not affected by ammonium ion. $H_2$ evolution was improved by increasing gene dosages of nitrogenase-coding genes, nifHDK in trans in glnB-glnK double mutant.

Human Y Chromosome: Structure, Function and Evolution (인간 Y 염색체: 구조, 기능 그리고 진화)

  • 홍경원;허재원;김희수
    • Journal of Life Science
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    • v.13 no.6
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    • pp.958-969
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    • 2003
  • The human Y chromosome is strictly paternally inherited and does not X-Y crossing over during male meiosis in most of its length. Although this region came to be known as the non-recombining region Y (NRY), it was renamed as male-specific region Y (MSY) due to abundant recombination. The MSY is a mosaic of heterochromatic sequences and three classes of euchromatic sequences: X-transposed, X-degenerated and ampliconic. The X-transposed sequences exhibit 99% identity to the X chromosomal sequences. The X-degenerate sequences are remnants of ancient autosomes from which the modem X and Y chromosomes evolved. Eight palindromes of the ampliconic comprise one-quarter of the euchromatic DNA of the male-specific region of the human Y chromosome. They contain many testis-specific genes and typically exhibit 99.97% intra-palindromic (arm-to-arm) sequence identity. The arms of these palindromes must have subsequently engaged in gene conversion, driving the pair arms to evolve it concert. Averages of approximately 600 nucleotides per newborn male have undergone Y-Y gene conversion, which has had an important role in the evolution of multi-copy testis gene families in the MSY.

Genetic Evolution and Characteristics of Ichthyotoxic Cochlodinium polykrikoides(Gymnodiniales, Dinophyceae) (어류치사성 Cochlodinium polykrikoides 적조생물의 유전적 진화 및 특성)

  • Cho, Eun-Seob;Jeong, Chang-Su
    • Journal of Life Science
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    • v.17 no.11
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    • pp.1453-1463
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    • 2007
  • This study presents a molecular phylogenetic analysis of the harmful dinoflagellate Cochlodinium polykrikoides, by use of partial sequence of small subunit (SSU) rRNA gene from most of the major taxa(24 species) in dinoflagellates. The class Dinophyceae clade formed a strong monophyletic relationship with C. polykrikoides and several taxa. On the basis of deeper nodes, the phylogenetic relationships placed C. polykrikoides closer to the order Prorocentrales rather than to the order Gymnodiniales, which was supported by a strong bootstrap value (100%) in the analyses of Neighbor-Joining and Parsimony methods. There is strong support for C. polykrikoides being placed in the same branch as Gymnodiniaceae and being connected in a clade with Prororcentrum micans among Prorocentrales. Morphological data show that C. polykrikoides is well associated with the genus Gyrodinium; however, this species is genetically closer to Gymnodinium than to Gyrodinium. The placement of C. polykrikoides always formed an independent branch separated from other dinoflagellates. In conclusion, planktonic P. micans plays an important role as an ancestor of Gymnodinium, whereas C. polykrikoides appears to be used an intermediate position between P. micans and Gymnodinium based on evolution.

Genomic Insights into the Rice Blast Fungus through Estimation of Gene Emergence Time in Phylogenetic Context

  • Choi, Jaeyoung;Lee, Jong-Joon;Jeon, Junhyun
    • Mycobiology
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    • v.46 no.4
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    • pp.361-369
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    • 2018
  • The rice blast fungus, Magnaporthe oryzae, is an important pathogen of rice plants. It is well known that genes encoded in the genome have different evolutionary histories that are related to their functions. Phylostratigraphy is a method that correlates the evolutionary origin of genes with evolutionary transitions. Here we applied phylostratigraphy to partition total gene content of M. oryzae into distinct classes (phylostrata), which we designated PS1 to PS7, based on estimation of their emergence time. Genes in individual phylostrata did not show significant biases in their global distribution among seven chromosomes, but at the local level, clustering of genes belonging to the same phylostratum was observed. Our phylostrata-wide analysis of genes revealed that genes in the same phylostratum tend to be similar in many physical and functional characteristics such as gene length and structure, GC contents, codon adaptation index, and level of transcription, which correlates with biological functions in evolutionary context. We also found that a significant proportion of genes in the genome are orphans, for which no orthologs can be detected in the database. Among them, we narrowed down to seven orphan genes having transcriptional and translational evidences, and showed that one of them is implicated in asexual reproduction and virulence, suggesting ongoing evolution in this fungus through lineage-specific genes. Our results provide genomic basis for linking functions of pathogenicity factors and gene emergence time.

Influences of Coating Cycles and Composition on the Properties of Dimensionally Stable Anode for Cathodic Protection

  • Yoo, Y.R.;Chang, H.Y.;Take, S.;Kim, Y.S.
    • Corrosion Science and Technology
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    • v.5 no.2
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    • pp.45-51
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    • 2006
  • Properties of the anode for cathodic protection need low overvoltage for oxygen evolution and high corrosion resistance. It is well known that DSA (Dimensionally Stable Anode) has been the best anode ever since. DSA is mainly composed of $RuO_2$, $IrO_2$, $ZrO_2$, $Co_2O_3$, and also $Ta_2O_5$, $TiO_2$, $MnO_2$ are added to DSA for better corrosion resistance. The lifetime of DSA for cathodic protection is also one of the very important factors. $RuO_2$, $IrO_2$, $RhO_2$, $ZrO_2$ are well used for life extension, and many researches are focused on life extension by lowering oxygen evolution potential and minimizing dissolution of oxide coatings. This work aims to evaluate the influence of constituents of MMO and coating cycles and $ZrO_2$ coating on the electrochemical properties and lifetime of DSA electrodes. From the results of lifetime assessment in the anodes coated with single component, $RuO_2$ coating was more effective and showed longer lifetime than $IrO_2$ coating. Also, an increased coating cycle and an electrochemically coated $ZrO_2$ could enhance the lifetime of a DSA.

Design and Implementation of a Multi-Intelligent Agent based Platform for a Bio-Inspired System (생태계 모방 시스템을 위한 멀티 지능형 에이전트 기반의 플랫폼 설계 및 구현)

  • Moon, Joo-Sun;Nang, Jong-Ho
    • Journal of KIISE:Computing Practices and Letters
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    • v.13 no.7
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    • pp.545-549
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    • 2007
  • The Bio-Inspired System focuses on the creation of an effective system model for massive network applications and is being widely developed. However, the system has a problem-difficulty implementing three features in the system, which includes scalability, adaptability and survivability. To solve this problem, we designed an Ecogent as a multiple intelligence agent, and a Bio-platform to address the three features of scalability, adaptability and survivability. The Bio-Inspired System Platform consists of an ERS (Ecogent Runtime Services) Platform and a Bio-Platform. The ERS platform serves the basic functions of mobile agents, such as Registration, Life Cycle, Migration, Communication, Location and Fault Tolerance. The Bio-Platform includes the functions of Evolution Control and Stigmergy Control to address evolution and adaptation.