• Title/Summary/Keyword: Evasion

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Development of Techer's Rating Scale of Elementary School Student's School Maladjustment (초등학생을 위한 학교부적응 척도 개발 및 타당화)

  • Jung, Jung-Soo;Oh, Ik-Soo
    • The Korean Journal of Elementary Counseling
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    • v.9 no.2
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    • pp.163-173
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    • 2010
  • This study was designed to develop a teacher's rating scale of elementary school student's school maladjustment. 50 behavior were drawn as elementary school student's school maladjustment behavior from the responses of elementary school teachers. To identify sub-factors of the scale, 60 teachers rated their 240 student's behavior and the collected data were analyzed by using factor analysis. 4 sub-factors were identified as the result : aggressive selfish behavior, misconduct of lesson and classroom rules, passive unsociable behavior and positive evasion of school activities. To identify the validity of the scale, the data from 120 students were analyzed through the concurrent validity between the scale and the teacher rating scale of school maladjustment for Student Problem Behavior Checklist for Elementary School students(Kim & Hwang, 2009). To examine the reliability of the scale, test-retest correlations were calculated by using the data from 120 students and internal consistency coefficients were calculated by using the data from 120 students. The results showed that Teacher's rating Scale of Elementary School Student's School Maladjustment was valid and reliable.

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Effect of Gasoline Property Change on Exhaust Gas and Catalyst (휘발유 물성변화에 따른 배출가스 및 촉매에 미치는 영향성 연구)

  • Noh, Kyeong-Ha;Kim, Sung-Woo;Lee, Min-Ho;Kim, Ki-Ho;Lee, Jung-Min
    • Journal of Power System Engineering
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    • v.22 no.6
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    • pp.67-73
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    • 2018
  • Gasoline that meets the quality standards is distributed in Korea. However, consumers who use toluene or solvent mixed with gasoline have appeared due to rising crude oil prices and for the purpose of tax evasion. Gasoline quality standard is enacted by the domestic and international research reference. A wrong fuel can influence automobile performance or environmental issue. Thus, empirical data from this issue is necessary. Therefore, this research observed catalyst influence by gasoline property change and inspect influence of environment. In this study, fuel property evaluation, lean-burn evaluation, and real vehicle exhaust emission test were performed. In the result of fuel property, the fuel "A" was measured to be up to 27% less octane than the normal gasoline and the distillation property was measured 24% higher than normal gasoline. In the test result of single cylinder engine lean-burn test, the fuels "A" and "B" show torque value 20% less than the normal gasoline. As a result of vehicle test using the catalyst, the fuel "A" was increased more than the normal gasoline with 83% THC, 1,806% CO and 128% NOx, and the fuel "B" was increased more than normal gasoline with 1.6% THC, 391% CO and 142% NOx.

Evaluation of circulating PD-1 and PD-L1 as diagnostic biomarkers in dogs with tumors

  • Song, Doo-Won;Ro, Woong-Bin;Park, Hee-Myung
    • Journal of Veterinary Science
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    • v.22 no.5
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    • pp.75.1-75.10
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    • 2021
  • Background: Programmed cell death protein-1 (PD-1) and programmed cell death ligand-1 (PD-L1) have important roles in tumor evasion of the immune system. Objectives: This study aimed to assess the diagnostic utility of circulating PD-1 and PD-L1 levels in healthy dogs and dogs with tumors. Methods: Circulating PD-1 and PD-L1 levels in the serum of 71 dogs with tumors were compared with those of 52 healthy dogs by performing enzyme-linked immunosorbent assay (ELISA). Results: The ELISA results revealed higher circulating PD-1 and PD-L1 levels in dogs with tumors (2.9 [2.2-3.7] ng/mL; median [IQR] and 2.4 [1.4-4.4] ng/mL, respectively) than in healthy dogs (2.4 [1.9-3.0] ng/mL; p = 0.012 and 1.4 [0.9-2.1] ng/mL; p < 0.001, respectively). Especially, there was a significant difference in circulating PD-1 levels between healthy dogs and dogs with malignant epithelial tumors (2.4 [1.9-3.0] ng/mL and 3.1 [2.6-4.4] ng/mL, respectively; p < 0.01). In addition, there was a significant difference in circulating PD-L1 levels between healthy dogs and dogs with lymphomas (1.4 [0.9-2.1] ng/mL and 2.7 [1.6-5.8] ng/mL, respectively; p < 0.001). Conclusion: This study indicates that circulating PD-1 and PD-L1 have potential as tumor diagnostic biomarkers in dogs with tumors.

Android Application Call Relationship Analysis Based on DEX and ELF Binary Reverse Engineering (DEX와 ELF 바이너리 역공학 기반 안드로이드 어플리케이션 호출 관계 분석에 대한 연구)

  • Ahn, Jinung;Park, Jungsoo;Nguyen-Vu, Long;Jung, Souhwan
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.29 no.1
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    • pp.45-55
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    • 2019
  • DEX file and share objects (also known as the SO file) are important components that define the behaviors of an Android application. DEX file is implemented in Java code, whereas SO file under ELF file format is implemented in native code(C/C++). The two layers - Java and native can communicate with each other at runtime. Malicious applications have become more and more prevalent in mobile world, they are equipped with different evasion techniques to avoid being detected by anti-malware product. To avoid static analysis, some applications may perform malicious behavior in native code that is difficult to analyze. Existing researches fail to extract the call relationship which includes both Java code and native code, or can not analyze multi-DEX application. In this study, we design and implement a system that effectively extracts the call relationship between Java code and native code by analyzing DEX file and SO file of Android application.

Middle East Respiratory Syndrome Coronavirus-Encoded Accessory Proteins Impair MDA5-and TBK1-Mediated Activation of NF-κB

  • Lee, Jeong Yoon;Bae, Sojung;Myoung, Jinjong
    • Journal of Microbiology and Biotechnology
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    • v.29 no.8
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    • pp.1316-1323
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    • 2019
  • Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerging coronavirus which is zoonotic from bats and camels. Its infection in humans can be fatal especially in patients with preexisting conditions due to smoking and chronic obstructive pulmonary disease (COPD). Among the 25 proteins encoded by MERS-CoV, 5 accessory proteins seem to be involved in viral evasion of the host immune responses. Here we report that ORF4a, ORF4b, and ORF8b proteins, alone or in combination, effectively antagonize nuclear factor kappa B ($NF-{\kappa}B$) activation. Interestingly, the inhibition of $NF-{\kappa}B$ by MERS-CoV accessory proteins was mostly at the level of pattern recognition receptors: melanoma differentiation-associated gene 5 (MDA5). ORF4a and ORF4b additively inhibit MDA5-mediated activation of $NF-{\kappa}B$ while that of retinoic acid-inducible gene 1 (RIG-I) is largely not perturbed. Of note, ORF8b was found to be a novel antagonist of MDA5-mediated $NF-{\kappa}B$ activation. In addition, ORF8b also strongly inhibits Tank-binding kinase 1 (TBK1)-mediated induction of $NF-{\kappa}B$ signaling. Taken together, MERS-CoV accessory proteins are involved in viral escape of $NF-{\kappa}B$-mediated antiviral immune responses.

Effect of Post Traumatic Stress Level Caused by Earthquake on Post Traumatic Growth: Focusing on the Mediating Effects of Stress Coping (지진에 의한 외상 후 스트레스 수준이 외상 후 성장에 미치는 영향: 스트레스 대처 방식의 매개효과를 중심으로)

  • Park, Hyung-Jun
    • Journal of the Society of Disaster Information
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    • v.16 no.4
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    • pp.658-669
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    • 2020
  • Purpose: This study was conducted for Pohang citizens who experienced Pohang earthquake damage. The purpose of this study is to examine how these post-traumatic stress level affect post-traumatic growth and to examine the mediating effects of stress coping on the causal relationship between post-traumatic stress level and post-traumatic growth. Method: The survey was conducted for the citizens who experienced Pohang earthquake, and the survey data were statistically analyzed using the SPSS 25.0 program. Result: Post traumatic stress level has been shown to affect post traumatic growth. In addition, as a result of examining the mediating effect of stress coping method on the relationship among these variables, the problem solving center and the social support method had a mediating effect, but the evasion method did not mediate. Conclusion: The post-traumatic stress level caused by disasters such as earthquakes was found to be able to overcome the obstacle and grow after trauma, as the coping method is problem solving and social support.

Real-Time File Access Event Collection Methodology for Zero Trust Environment (제로 트러스트 환경의 실시간 파일 접근 이벤트 수집 방법에 관한 연구)

  • Han, Sung-Hwa;Lee, Hoo-Ki
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.10
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    • pp.1391-1396
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    • 2021
  • The boundary-based security system has the advantage of high operational efficiency and easy management of security solutions, and is suitable for denying external security threats. However, since it is operated on the premise of a trusted user, it is not suitable to deny security threats that occur from within. A zero trust access control model was proposed to solve this problem of the boundary-based security system. In the zero trust access control model, the security requirements for real-time security event monitoring must be satisfied. In this study, we propose a monitoring method for the most basic file access among real-time monitoring functions. The proposed monitoring method operates at the kernel level and has the advantage of fundamentally preventing monitoring evasion due to the user's file bypass access. However, this study focuses on the monitoring method, so additional research to extend it to the access control function should be continued.

Research on the forming factors and overcoming of Jonah complex (요나 콤플렉스의 형성요인 및 극복방안 연구)

  • JIA, FULAN;Baek, Hyung-Ki
    • Industry Promotion Research
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    • v.6 no.3
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    • pp.79-88
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    • 2021
  • Jonah complex is a psychological term put forward by Maslow, a famous American psychologist. In short, "Jonah complex" is the fear of growth. It comes from a hypothesis in psychodynamic theory: "people are not only afraid of failure, but also afraid of success." It represents a kind of psychology of self-evasion and retreat in the face of opportunities. It is an emotional state, which leads us not to do what we can do well, or even to avoid exploring our potential. From the perspective of self-actualization, it is a psychological obstacle to self-actualization. This paper consists of the following parts: the first chapter describes the research background and significance of this paper; the second chapter describes the theoretical basis of this paper; the third chapter explains that the research method of this paper is literature method; the fourth chapter analyzes the reasons for the formation of Jonah complex in detail; the fifth chapter describes how to overcome Jonah complex.

Harnessing NK cells for cancer immunotherapy: immune checkpoint receptors and chimeric antigen receptors

  • Kim, Nayoung;Lee, Dong-Hee;Choi, Woo Seon;Yi, Eunbi;Kim, HyoJeong;Kim, Jung Min;Jin, Hyung-Seung;Kim, Hun Sik
    • BMB Reports
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    • v.54 no.1
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    • pp.44-58
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    • 2021
  • Natural killer (NK) cells, key antitumor effectors of the innate immune system, are endowed with the unique ability to spontaneously eliminate cells undergoing a neoplastic transformation. Given their broad reactivity against diverse types of cancer and close association with cancer prognosis, NK cells have gained considerable attention as a promising therapeutic target for cancer immunotherapy. NK cell-based therapies have demonstrated favorable clinical efficacies in several hematological malignancies but limited success in solid tumors, thus highlighting the need to develop new therapeutic strategies to restore and optimize anti-tumor activity while preventing tumor immune escape. The current therapeutic modalities yielding encouraging results in clinical trials include the blockade of immune checkpoint receptors to overcome the immune-evasion mechanism used by tumors and the incorporation of tumor-directed chimeric antigen receptors to enhance NK cell anti-tumor specificity and activity. These observations, together with recent advances in the understanding of NK cell activation within the tumor microenvironment, will facilitate the optimal design of NK cell-based therapy against a broad range of cancers and, more desirably, refractory cancers.

Adversarial Example Detection and Classification Model Based on the Class Predicted by Deep Learning Model (데이터 예측 클래스 기반 적대적 공격 탐지 및 분류 모델)

  • Ko, Eun-na-rae;Moon, Jong-sub
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.31 no.6
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    • pp.1227-1236
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    • 2021
  • Adversarial attack, one of the attacks on deep learning classification model, is attack that add indistinguishable perturbations to input data and cause deep learning classification model to misclassify the input data. There are various adversarial attack algorithms. Accordingly, many studies have been conducted to detect adversarial attack but few studies have been conducted to classify what adversarial attack algorithms to generate adversarial input. if adversarial attacks can be classified, more robust deep learning classification model can be established by analyzing differences between attacks. In this paper, we proposed a model that detects and classifies adversarial attacks by constructing a random forest classification model with input features extracted from a target deep learning model. In feature extraction, feature is extracted from a output value of hidden layer based on class predicted by the target deep learning model. Through Experiments the model proposed has shown 3.02% accuracy on clean data, 0.80% accuracy on adversarial data higher than the result of pre-existing studies and classify new adversarial attack that was not classified in pre-existing studies.