• Title/Summary/Keyword: Equipment Manufacturing Industry

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Basic study on high gradient magnetic separation of nano beads using superconducting magnet for antibody purification

  • Jeongtae Kim;Insung Park;Gwantae Kim;Myunghwan Sohn;Sanghoon Lee;Arim Byun;Jin-sil Choi;Taekyu Kim;Hongsoo Ha
    • Progress in Superconductivity and Cryogenics
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    • v.25 no.4
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    • pp.60-64
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    • 2023
  • The manufacturing process of antibody drugs comprises two main stages: the upstream process for antibody cultivation and the downstream process for antibody extraction. The domestic bio industry has excellent technology for the upstream process. However, it relies on the technology of foreign countries to execute downstream process such as affinity chromatography. Furthermore, there are no domestic companies capable of producing the equipment for affinity chromatography. High gradient magnetic separation technology using a high temperature superconducting magnet as a novel antibody separation and purification technology is introduced to substitute for the traditional technology of affinity chromatography. A specially designed magnetic filter was equipped in the bore of the superconducting magnet enabling the continuous magnetic separation of nano-sized paramagnetic beads that can be used as affinity magnetic nano beads for antibodies. To optimize the magnetic filter that captures superparamagnetic nanoparticles effectively, various shapes and materials were examined for the magnetic filter. The result of magnetic separation experiments show that the maximum separation and recovery ratio of superparamagnetic nanoparticles are 99.2 %, and 99.07 %, respectively under magnetic field (3 T) and flow rate (600 litter/hr).

Development of Auto-spray system to improve the quality of 3D Scanning Quality (3D 스캔 시 품질향상을 위한 스프레이 도포 자동화 장비 개발)

  • Kim, Wonseop;Jo, Jae Heung;Kim, Dongsu;Kim, Donggyoo;Hong, Seokmoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.100-105
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    • 2016
  • The use of 3D scanners has increased gradually according to increasing 3D printer applications. The precision inspection of car parts or electronic components is an important issue not only in the field of mass production, but also in small-scale production. Recently, 3D scanner equipment efficiency and recognition technology has been improved continuously. On the other hand, the spraying time to prepare 3D scanning is time-consuming and has environmental problems. Therefore, an automatic spray system has been in demand by the manufacturing industry. Automatic spray equipment was newly developed for the preparation of a 3D scanner. In this research, the automatic spray system guarantees uniform spray operation. To determine the optimal spray parameters, various spraying methods, solutions and conditions were tested and compared with the experiments. The preparation time for 3D scanning was reduced to 1/10 compared to the manual spraying time, and indicates the optimal spraying conditions through a comparison of various spray coating conditions.

A Study on the Teacher's perception in Vocational High School for the Subject of NCS-based Metal Machining (NCS기반 절삭가공 실무과목 수업에 대한 특성화고 기계계열 교사의 인식)

  • Park, Su-han;Kim, Jin-soo
    • 대한공업교육학회지
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    • v.45 no.1
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    • pp.42-62
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    • 2020
  • The Ministry of Education has been quick to apply National Competency Standars (NCS) to industrial sites and educational·training institutions in order to resolve discrepancies between practical affairs in industrial sites and vocational education, training & requirements. Full implementation of NCS-based curriculum in vocational education of vocational high schools has been mandatory since 2018. This research used a region-stratified sample of 350 from teachers in 'machinery' and 'machine·metal' majors in mechanical departments of vocational high schools to investigate the awareness of practical courses for metal machining among the teachers. The research results are as follows. First, a majority of the respondents indicated the availability of turning process, milling process, computer integrated manufacturing and measuring courses in mechanical departments. Second, capabilities required by the industry are considered most in selecting practical courses and competence units. Third, positive changes with the introduction of practical courses in the school education are students' practical skills improvement and satisfaction of industrial requirements. Fourth, negative changes with the introduction of practical courses in the school education are too difficult learning modules used in practical courses for students and students' difficulty in learning because of the difference between equipment in schools and industrial equipment in learning modules. Fifth, teachers' satisfaction with practical courses classes and overall conditions is above the average, and their satisfaction with the level of practical courses and bookbinding or purchase of rearranged textbooks of practical courses is below the average. Therefore, application conditions of above-mentioned representative 4 practical courses should be examined and taken care of for consistent improvement to stabilize NCS-based educational courses in mechanical departments.

Development of High Efficiency Dehumidifiers in low temperature (저온에서 고효율 제습기 개발)

  • Kim, Jong-Ryeol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.206-211
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    • 2016
  • Various applications require dry air at low temperature, such automation equipment, semiconductor manufacturing, chemical production lines, and coating processes for the shipbuilding industry. Four evaporators for low temperature (below $0^{\circ}C$) were installed for a dehumidification system. Moist air is cooled sequentially over three evaporators. The first evaporator has an evaporation temperature of $13^{\circ}C$, that of the second evaporator is $5^{\circ}C$, and that of the third evaporator is maintained at $-1.3^{\circ}C$. In the fourth evaporator implantation thereby the moisture contained in the moisture air. A pressure regulator (CPCE 12) is used at this point and is defrosted when the vapor pressure is below a set value. The non-implantation moisture of the air is a heating system that uses the waste heat of a condenser with high temperature. It develops the cooling type's dehumidifier, which is important equipment that prevents the destruction of protein and measures the temperature and humidity at each interval by changing the front air velocity from 1.0 m/s to 4.0 m/s. The cooling capacity was also calculated. The greatest cooling capacity was 1.77 kcal/h for a front air velocity of 2.0 m/s

Research on Digital twin-based Smart City model: Survey (디지털 트윈 기반 스마트 시티 모델 연구 동향 분석)

  • Han, Kun-Hee;Hong, Sunghyuck
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.172-177
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    • 2021
  • As part of the digital era, a digital twin that simulates the weak part of a product by performing a stress test that reduces the lifespan of some expensive equipment that cannot be done in reality by accurately moving the real world to virtual reality is being actively used in the manufacturing industry. Due to the development of IoT, the digital twin, which accurately collects data collected from the real world and makes it the same in the virtual space, is mutually beneficial through accurate prediction of urban life problems such as traffic, disaster, housing, quarantine, energy, environment, and aging. Based on its action, it is positioned as a necessary tool for smart city construction. Although digital twin is widely applied to the manufacturing field, this study proposes a smart city model suitable for the 4th industrial revolution era by using it to smart cities and increasing citizens' safety, welfare, and convenience through the proposed model. In addition, when a digital twin is applied to a smart city, it is expected that more accurate prediction and analysis will be possible by real-time synchronization between the real and virtual by maintaining realism and immediacy through real-time interaction.

Development of jigs for planar measurement with DIC and determination of magnesium material properties using jigs (마그네슘 합금 판재의 평면 DIC 측정을 위한 지그 개발과 이를 활용한 단축 변형 특성 분석)

  • Kang, Jeong-Eun;Yoo, Ji-Yoon;Choi, In-Kyu;YU, Jae Hyeong;Lee, Chang-Whan
    • Design & Manufacturing
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    • v.15 no.2
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    • pp.23-29
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    • 2021
  • The specific strength of magnesium alloy is four times that of iron and 1.5 times that of aluminum. For this reason, its use is increasing in the transportation industry which is promoting weight reduction. At room temperature, magnesium alloy has low formability due to Hexagonal closed packed (HCP) structure with relatively little slip plane. However, as the molding temperature increases, the formability of the magnesium alloy is greatly improved due to the activation of other additional slip systems, and the flow stress and elongation vary greatly depending on the temperature. In addition, magnesium alloys exhibit asymmetrical behavior, which is different from tensile and compression behavior. In this study, a jig was developed that can measure the plane deformation behavior on the surface of a material in tensile and compression tests of magnesium alloys in warm temperature. A jig was designed to prevent buckling occurring in the compression test by applying a certain pressure to apply it to the tensile and compression tests. And the tensile and compressive behavior of magnesium at each temperature was investigated with the developed jig and DIC equipment. In each experiment, the strain rate condition was set to a quasi-static strain rate of 0.01/s. The transformation temperature is room temperature, 100℃. 150℃, 200℃, 250℃. As a result of the experiment, the flow stress tended to decrease as the temperature increased. The maximum stress decreased by 60% at 250 degrees compared to room temperature. Particularly, work softening occurred above 150 degrees, which is the recrystallization temperature of the magnesium alloy. The elongation also tended to increase as the deformation temperature increased and increased by 60% at 250 degrees compared to room temperature. In the compression experiment, it was confirmed that the maximum stress decreased as the temperature increased.

Process Optimization for the Industrialization of Transparent Conducting Film (투명 전도막의 산업화를 위한 공정 최적화)

  • Nam, Hyeon-bin;Choi, Yo-seok;Kim, In-su;Kim, Gyung-jun;Park, Seong-su;Lee, Ja Hyun
    • Industry Promotion Research
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    • v.9 no.1
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    • pp.21-29
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    • 2024
  • In the rapidly advancing information society, electronic devices, including smartphones and tablets, are increasingly digitized and equipped with high-performance features such as flexible displays. This study focused on optimizing the manufacturing process for Transparent Conductive Films (TCF) by using the cost-effective conductive polymer PEDOT and transparent substrate PET as alternatives to expensive materials in flexible display technology. The variables considered are production speed (m/min), coating maximum temperature (℃), and PEDOT supply speed (rpm), with surface resistivity (Ω/□) as the response parameter, using Response Surface Methodology (RSM). Optimization results indicate the ideal conditions for production: a speed of 22.16 m/min, coating temperature of 125.28℃, and PEDOT supply at 522.79 rpm. Statistical analysis validates the reliability of the results (F value: 18.37, P-value: < 0.0001, R2: 0.9430). Under optimal conditions, the predicted surface resistivity is 145.75 Ω/□, closely aligned with the experimental value of 142.97 Ω/□. Applying these findings to mass production processes is expected to enhance production yields and decrease defect rates compared to current practices. This research provides valuable insights for the advancement of flexible display manufacturing.

Simulation analysis of AGV introduction in the convenience store logistics distribution centers (편의점 유통물류센터의 AGV 도입에 대한 시뮬레이션 분석)

  • Kim, Jeonghoon;Kim, Younjin;Lee, Hongchul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.6
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    • pp.61-69
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    • 2016
  • Since 2000, the market of convenient stores in Korea has developed rapidly due to the explosive growth in single households but it still consists mainly of manual work due to the nature of the domestic industry. Hence the explosive increase in demand in the market is mostly due to workers. Therefore, the research aimed at encouraging efficiency via automation, which is carried out in manufacturing, such as electronic, cars and so on, is inadequate. This study performed a feasibility analysis of investment for introducing an automated system on brand A, which is domestic famous convenience store company. Productivity growth according to the introduction of an automated guided vehicle and the cost-benefits was studied with using a simulation for the picking process, which is most personnel and time consuming. As a result, the simulation showed that the equipment AGV introduced for choosing the process has the effects of cost saving and increased time efficiency for performing manual labor. Furthermore, appropriate numbers of AGV were forecasted considering the capacity of the distribution Center in the brand A convenient store, which has been growing steadily. There are increasing numbers of worker labor costs in the distribution industry these days. Before building a large new automate center, it is expected to provide a good information to investors who are considering increasing productivity through partial automation of each of unit process to achieve some cost reduction.

The Impact of Enterprise R&D Investment on Inter-industry Technology Spillover in Korea under the new Normal Era (뉴 노멀 시대하 한국기업의 R&D투자가 산업간 기술파급에 미치는 영향)

  • Kim, Seon Jae;Lee, Younghwa
    • The Journal of the Korea Contents Association
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    • v.13 no.2
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    • pp.390-399
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    • 2013
  • The purpose of this study is to examine the impact of enterprise R&D investment on inter-industry technology spillover in Korea under the new Normal Era. In order to do this, we tested the effect of production inducement, backward and forward linkage effects, and the effect of technology spillover such as technology intensity effects and technology diffusion effects based on an input-output framework. The results show that the high index industries of the production inducement effect were professional, scientific and technical activities, manufacture of metal products, and general machinery. Some manufacturers of other non-metallic mineral products and transport equipment sectors appeared to have the strong effect of forward and backward linkages that were almost equivalent to high-tech manufacturing industries. In particular, the industries of professional, scientific and technical activities appeared to have the strong effect of both forward and backward linkages. Therefore, we need to drive a strong policy support to higher enterprise R&D investment in the those particular industries not only to increase global competitiveness, but also to widen up the technology spillover effect on other industries.

An Empirical Analysis on the Working Conditions of Construction Technician (건설 기능인력 근무여건에 대한 실증 분석)

  • Yang, Jinkook;Lee, Taeshin;Lee, Jongmin;Lee, Sangbeom
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.1
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    • pp.14-21
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    • 2019
  • The construction phase of the construction project needs a large scale of manpower, materials and equipment. Among them, manpower is a core part for project construction. These manpower are divided into two groups. The first is the management group that manages the construction, and the second is the site technician manpower for construction work. Recently, construction company has suffering due to the insufficient supply of technician labor. Accordingly, this study will perform an empirical analysis about the construction technician. To do this, we surveyed related research trends and conducted surveys on the satisfaction of the construction technician. The result, satisfaction with pay and insurance was relatively low compared to other items. Therefore, this study were conducted in-depth interviews with technician managers in order to analyze the cause. In addition, case analysis was conducted to analyze actual working conditions. As a result, it was analyzed that the wage level and insurance system of construction technician were considerably stable compared to the manufacturing industry. The result of this study is expected to contribute to the activation of excellent technician cultivation through the change of recognition about construction technician.