• Journal of Integrative Natural Science
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• v.6 no.3
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• pp.138-142
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• 2013

The HIV-1 envelope glycoprotein gp120 plays a vital role in the entry of the virus into the host cells. The crucial role of the glycoprotein suggests gp120 as potential drug target for the future antiviral therapies. Identification of the binding mode of small drug like compounds has been an important goal in drug design. In the current study we attempt to propose binding mode of indole derivatives in the binding pocket of gp120. These derivatives are reported to inhibit HIV-1 by acting as attachment inhibitors that bind to gp120 and prevent the gp120-CD4 interaction and thus inhibit the infectivity of HIV-1. To elucidate the molecular basis of the small molecules interactions to inhibit the glycoprotein function we employed the molecular docking simulation approach. This study provides insights to elucidate the binding pattern of indole-based gp120 inhibitors and may help in the rational design of novel HIV-1 inhibitors with improved potency.

• Proceedings of the IEEK Conference
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• 1998.06a
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• pp.106-109
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• 1998

Wireless communication systems, in particular, must operate in a crowded electro-magnetic environmnet where in-band undesired signals are treated as noise by the receiver. These interfering signals are often random but not Gaussian Due to nongaussian noise, the distribution of the observables cannot be specified by a finite set of parameters; instead r-dimensioal sample space (pure noise samples) is equiprobably partitioned into a finite number of disjointed regions using quantiles and a vector quantizer based on training samples. If we assume that the detected symbols are correct, then we can observe the pure noise samples during the training and transmitting mode. The algorithm proposed is based on a piecewise approximation to a regression function based on quantities and conditional partition moments which are estimated by a RMSA (Robbins-Monro Stochastic Approximation) algorithm. In this paper, we develop a diversity combiner with modified detector, called Non-Linear Detector, and the receiver has a differential phase detector in each diversity branch and at the combiner each detector output is proportional to the second power of the envelope of branches. Monte-Carlo simulations were used as means of generating the system performance.

• Korean Journal of Optics and Photonics
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• v.7 no.4
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• pp.403-413
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• 1996

We study the propagation of two pulses with orthogonal linear polarizations in a nonlinear periodic dielectric structure with $X^{(3)}$ nonlinearity. Using an envelope- function approach, we derive the coupled nonlinear Schrodinger equations governing the spatio-temporal evolutions of the two orthogonally polarized modes in a nonlinear periodic structure. We then find their solitary-wave solutions referred to as coupled gap solitons. We show that two orthogonally polarized pulses can co-propagate as a coupled gap soliton through a nonlinear periodic structure while each pulse alone will be strongly reflected due to the Bragg reflection. Based on the results, we present an all-optical switching scheme which has a novel architecture and principle. We also study the stability of coupled gap solitons to find the dragging phenomena in a nonlinear birefringent periodic medium.

• KIEAE Journal
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• v.4 no.3
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• pp.121-128
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• 2004

One of the most weak parts for energy loss through the whole building components are building envelopes. Lots of technbologies to increase the thermal performance of building envelopes have been introduced in recent years. Transparent insulation is a new technology for building insulation and has function both solar transmittance and thermal insulation. This study has been carried out to develope the transparent insulation panels and TI-wall system and to analyze the thermal performance of TI-wall system by experiments using test-cell and dynamic energy simulation program ESP-r 9.0. This system is regarded as a efficient building envelope system suitable for to reduce the heating and cooling load of the buildings in our country.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.11
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• pp.2978-2990
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• 1996

With the advent of multimedia era, there are ever increasing interest in computer music and sound syntheis. An FM type sound synthesizing method makes possible the syntheis ofvarious sounds ofmusical instruments with a relatively simple hardware architecture. Therefore, in this paper, we designed a hardware architecture for real-time sound synthesizer and its logic gates. In this paper, we designed a basic sound generator for implementation of real-time logic gates, analzed characteristics of sounds synthesized in this architecture and extracted parameters of FM sounds of musical instruments by using the Csound software. The major bolkcs to build the hardware are a phase-generator, a singe-function-generator, an envelope-generator and a multiplier-part. Finally, logic circuits are designed and verified in VHDL and logic gates by 1.0um standard cell library, which will be easily implementable by the form of ASIC.

• Journal of The Korean Astronomical Society
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• v.49 no.1
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• pp.1-8
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• 2016

The aim of this study is to describe the physical processes taking place in the solar photosphere. Based on 3D hydrodynamic simulations including a detailed radiation transfer scheme, we investigate thermodynamic structures and radiation fields in solar surface convection. As a starting model, the initial stratification in the outer envelope calculated using the solar calibrations in the context of the standard stellar theory. When the numerical fluid becomes thermally relaxed, the thermodynamic structure of the steady-state turbulent flow was explicitly collected. Particularly, a non-grey radiative transfer incorporating the opacity distribution function was considered in our calculations. In addition, we evaluate the classical approximations that are usually adopted in the onedimensional stellar structure models. We numerically reconfirm that radiation fields are well represented by the asymptotic characteristics of the Eddington approximation (the diffusion limit and the streaming limit). However, this classical approximation underestimates radiation energy in the shallow layers near the surface, which implies that a reliable treatment of the non-grey line opacities is crucial for the accurate description of the photospheric convection phenomenon.

• Journal of the Earthquake Engineering Society of Korea
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• v.21 no.6
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• pp.295-301
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• 2017

This paper relates to the study of load characteristics applicable to wind turbine generators induced by earthquakes. An artificial design earthquake wave generated through the target spectrum and the envelope function of Richter Magnitude Scale (ML) 7.0 as in ASCE4-98 was created. A simulation of earthquake loads were performed according to the design load cases (DLC) 9.5~9.7 of GL guidelines. Additionally, simulation of seismic loads experienced by Wind Turbines installed in the Gyeongju region were carried out utilizing artificial earthquakes of ML 5.8 simulating the real earthquakes during the Gyeongju Earthquakes of Sept. 2016.

• ETRI Journal
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• v.20 no.4
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• pp.361-379
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• 1998

We present an improved transfer matrix algorithm which can be used in solving general n-band effective-mass $Schr{\ddot{o}}dinger$ equation for quantum well structures with arbitrary shaped potential profiles(where n specifies the number of bands explicitly included in the effective-mass equation). In the proposed algorithm, specific formulas are presented for the three-band (the conduction band and the two heavy- and light-hole bands) and two-band (the heavy- and light-hole bands) effective-mass eigensystems. Advantages of the present method can be taken in its simple and unified treatment for general $n{\times}n$ matrix envelope-function equations, which requires relatively smaller computation efforts as compared with existing methods of similar kind. As an illustration of application of the method, numerical computations are performed for a single GaAs/AlGaAs quantum well using both the two-band and three-band formulas. The results are compared with those obtained by the conventional variational procedure to assess the validity of the method.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.13 no.1
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• pp.21-27
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• 2000

We used the surface photovoltage spectroscopy(SPVS) for characterization of GaAs/Al\ulcornerGa\ulcornerAs multi-quantum well(MQW) structures grown by molecular beam epitaxy(MBE) method. Energy gap related transitions in GaAs and AlGaAs were observed. The Al composition(x=0.3) was determined by Sek's composition formula. Transition energies in MQW were determined using the differential surface photo-volatage spectroscopy)DSPVS) of the measured resonanced. In order to indentify the transitions, the experimentally observed energies were compared with results of the envelope function approximation for a rectangular quantum well. We have observed and interesting behavior of the temperature dependence(80K~300K) of the 11Hand 11L transition for sample.

• Proceedings of the KOSOMBE Conference
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• v.1991 no.11
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• pp.79-82
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• 1991

Digital FHR monitoring system based on the personal computer combined wi th the digital signal processing (DSP) board was implemented. The DSP board acquires and digitally processes ultrasound fetal Doppler signal for digital rectification, envelope detection, autocorrealtion function calculation and its peak position detection. The personal computer interfaced with the DSP board is in charge of graphic display, hardcopy, data taransmission and on-line analysis of fetal heart rate change including on-line warning system, base-line estmation, acceleration, deceleration and variability. The advantages of PC-DSP based system can be summarized as follows: 1) Minimum hardware realization. 2) Increased flexibility. 3) Total care system.