• Title/Summary/Keyword: Enabling conditions

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Characterization and Evaluation of Freeze-dried Liposomes Loaded with Ascorbyl Palmitate Enabling Anti-aging Therapy of the Skin

  • Lee, Sang-Kil;Lee, Jae-Hwi;Choi, Young-Wook
    • Bulletin of the Korean Chemical Society
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    • 제28권1호
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    • pp.99-102
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    • 2007
  • To prepare freeze-dried ascorbyl palmitate (AsP)-containing liposome which can protect the drug from moisture attack and be used instantly by mixing with water for anti-aging and skin whitening therapy, AsP was encapsulated into liposomes and freeze-dried with trehalose. The freeze-dried liposome formulations were characterized by measuring water contents, particle size, time required for complete reconstitution. With the freeze-dried liposomes, we performed the stability test under accelerated conditions, skin permeation and localization test. The measurement of the time to perfect reconstitution showed that the freeze-dried liposomes can be changed to their initial state rapidly and short term stability test of AsP in reconstituted liposomes under accelerated conditions confirmed that the stability of AsP was considerably enhanced as compared to freshly prepared liposomes. The skin permeation and localization properties of AsP in reconstituted liposomes were not significantly different, indicating that the liposomal structures were maintained before and after freezedrying. In conclusion, the freeze-drying method provided a possible way to overcome the instability issue of AsP induced by the moisture and reproduced similar skin permeation and localization properties as shown by freshly prepared liposomes.

Analysis of pipe thickness reduction according to pH in FAC facility with In situ ultrasonic measurement real time monitoring

  • Oh, Se-Beom;Kim, Jongbeom;Lee, Jong-Yeon;Kim, Dong-Jin;Kim, Kyung-Mo
    • Nuclear Engineering and Technology
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    • 제54권1호
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    • pp.186-192
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    • 2022
  • Flow accelerated corrosion (FAC) is a type of pipe corrosion in which the pipe thickness decreases depending on the fluid flow conditions. In nuclear power plants, FAC mainly occurs in the carbon steel pipes of a secondary system. However, because the temperature of a secondary system pipe is over 150 ℃, in situ monitoring using a conventional ultrasonic non-destructive testing method is difficult. In our previous study, we developed a waveguide ultrasonic thickness measurement system. In this study, we applied a waveguide ultrasonic thickness measurement system to monitor the thinning of the pipe according to the change in pH. The Korea Atomic Energy Research Institute installed FAC-proof facilities, enabling the monitoring of internal fluid flow conditions, which were fixed for ~1000 h to analyze the effect of the pH. The measurement system operated without failure for ~3000 h and the pipe thickness was found to be reduced by ~10% at pH 9 compared to that at pH 7. The thickness of the pipe was measured using a microscope after the experiment, and the reliability of the system was confirmed with less than 1% error. This technology is expected to also be applicable to the thickness-reduction monitoring of other high-temperature materials.

Current concepts of vascular anomalies

  • Tae Hyung Kim;Jong Woo Choi;Woo Shik Jeong
    • 대한두개안면성형외과학회지
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    • 제24권4호
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    • pp.145-158
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    • 2023
  • Vascular anomalies encompass a variety of malformations and tumors that can result in severe morbidity and mortality in both adults and children. Advances have been made in the classification and diagnosis of these anomalies, with the International Society for the Study of Vascular Anomalies establishing a widely recognized classification system. In recent years, notable progress has been made in genetic testing and imaging techniques, enhancing our ability to diagnose these conditions. The increasing sophistication of genetic testing has facilitated the identification of specific genetic mutations that help treatment decisions. Furthermore, imaging techniques such as magnetic resonance imaging and computed tomography have greatly improved our capacity to visualize and detect vascular abnormalities, enabling more accurate diagnoses. When considering reconstructive surgery for facial vascular anomalies, it is important to consider both functional and cosmetic results of the procedure. Therefore, a comprehensive multidisciplinary approach involving specialists from dermatology, radiology, and genetics is often required to ensure effective management of these conditions. Overall, the treatment approach for facial vascular anomalies depends on the type, size, location, and severity of the anomaly. A thorough evaluation by a team of specialists can determine the most appropriate and effective treatment plan.

Driving with an Adaptive Cruise Control System

  • Nam, Hyoung-Kwon;Lee, Woon-Sung
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.717-722
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    • 2003
  • A driving simulator is a computer-controlled tool to study an interface between a driver and vehicle response by enabling the driver to participate in judging vehicle characteristics. Using the driving simulator, human factor study, vehicle system development and other research can be effectively done under controllable, reproducible and non-dangerous conditions. An Adaptive Cruise Control (ACC) system is generally regarded as a system that can be achieved in the near future without the demanding infrastructure components and technologies. ACC system is an automatic vehicle following system with no human engagement in the longitudinal vehicle direction. And the influence of the driver is substantial in developing the system. Driving characteristic is very different according to the accident riskiness, gender, age and so on. In this research, experiments have been carried out to investigate driving characteristics with the ACC system, using a driving simulator. Participants are 21 male and 19 female. Driving characteristics such as preferred headway-time, lane keeping ability, eye direction, and head movement have been observed and compared between the driving with ACC and the driving without ACC.

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Analysis Model Evaluation based on IoT Data and Machine Learning Algorithm for Prediction of Acer Mono Sap Liquid Water

  • Lee, Han Sung;Jung, Se Hoon
    • 한국멀티미디어학회논문지
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    • 제23권10호
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    • pp.1286-1295
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    • 2020
  • It has been increasingly difficult to predict the amounts of Acer mono sap to be collected due to droughts and cold waves caused by recent climate changes with few studies conducted on the prediction of its collection volume. This study thus set out to propose a Big Data prediction system based on meteorological information for the collection of Acer mono sap. The proposed system would analyze collected data and provide managers with a statistical chart of prediction values regarding climate factors to affect the amounts of Acer mono sap to be collected, thus enabling efficient work. It was designed based on Hadoop for data collection, treatment and analysis. The study also analyzed and proposed an optimal prediction model for climate conditions to influence the volume of Acer mono sap to be collected by applying a multiple regression analysis model based on Hadoop and Mahout.

티타늄금속기 복합재료의 강화공정에 관한 미시역학적 모델링 (Micro-mechanical Modeling of the Consolidation Processes in Titanium Metal Matrix Composites)

  • 김준완;김태원
    • 한국복합재료학회:학술대회논문집
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    • 한국복합재료학회 2002년도 춘계학술발표대회 논문집
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    • pp.207-210
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    • 2002
  • Metal matrix composites(MMCs) are increasingly attractive for high technology components such as aerospace applications and transportations due to their high strength, stiffness, and toughness. Many processes for fabricating MMCs have been developed, and relatively simple Foil-Fiber-Foil method is usually employed in solid state consolidation processes. During the consolidation processes at high temperature, densification occurs by the inelastic flow of the matrix materials, and the process is coupled with the conditions of pressure, temperature and volume fraction of fiber and matrix materials. This is particularly important in titanium matrix composites, and thus a generic model based on micro-mechanical approaches enabling the evolution of density over time to be predicted has been developed. The mode developed is then implemented into FEM so that practical process simulation has been carried out. Further the experimental investigation of the consolidation behavior of SiC/Ti-6Al-4V composites using vacuum hot pressing has been performed, and the results obtained are compared with the model predictions.

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A Realtime Analytical System of Football Game

  • Min, Dae-kee
    • Communications for Statistical Applications and Methods
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    • 제8권2호
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    • pp.557-564
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    • 2001
  • The objective of he study is to record the real conditions along with the soccer ball that is, each player's ball keeping time, the number football keeping, accuracy of passing to other player, direction, etc., on a real-time basis, measure them in numbers and get necessary analyzed output as much as one needs. The study consists of the following stages: (1) Record the data by drawing through Visual Interface on a real-time basis; (2) Graphic windows to display the recorded data item by item in graphic; (3) Form windows to display the individual or team scores anytime when needed; (4) Windows to display the analyzed data in visualized form. The effect of the study is threefold: (1) It inputs all the game-related data on a real-time basis, which was impossible before and shows analyzed contents during the game enabling each tea manager o use; (2) In cse of TV broadcasting or newspaper articles, it explains objectively the situations of he game to the TV viewers or readers; (3) After the game, it provides importance information on each team's playing ability and individual player's technical improvement through data analysis.

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Improved flame retardant performance of cellulose fibers following fluorine gas treatment

  • Kim, Jong Gu;Lee, Young-Seak;In, Se Jin
    • Carbon letters
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    • 제28권
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    • pp.66-71
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    • 2018
  • To improve the flame retardant performance of cellulose fibers, fluorine functional groups were introduced under various controlled fluorination conditions. The properties of the fluorinated cellulose fibers were analyzed by X-ray photoelectron spectroscopy and a thermogravimetric analysis. The fluorine functional group content in the fluorinated cellulose fibers increased with an increase in the fluorination temperature. However, the fluorination reaction increased the char yield and decreased the rate of degradation of the cellulose fibers by introducing donors, enabling the formation of a thick and compact char layer. Therefore, the flame retardant properties of cellulose fibers were improved following the fluorination treatment.

터널 막장면 고해상도 DEM(Digital Elevation Model) 생성에 관한 연구 (A Study on Developing a High-Resolution Digital Elevation Model (DEM) of a Tunnel Face)

  • 김광염;김창용;백승한;홍성완;이승도
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2006년도 춘계 학술발표회 논문집
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    • pp.931-938
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    • 2006
  • Using high resolution stereoscopic imaging system three digital elevation model of tunnel face is acquired. The images oriented within a given tunnel coordinate system are brought into a stereoscopic vision system enabling three dimensional inspection and evaluation. The possibilities for the prediction ahead and outside of tunnel face have been improved by the digital vision system with 3D model. Interpolated image structures of rock mass between subsequent stereo images will enable to model the rock mass surrounding the opening within a short time at site. The models shall be used as input to numerical simulations on site, comparison of expected and encountered geological conditions, and for the interpretation of geotechnical monitoring results.

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Green Frame 접합방식 기초연구 (A Basic Research for Connection Type of Green Frame)

  • 김근호;주진규;임채연;김선국
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2011년도 추계 학술논문 발표대회
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    • pp.171-172
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    • 2011
  • Green column and green beam, key structural members of green frame, have the characteristics of post-lintel structure, thanks to the steel frame in the connection, enabling prompt and precise installation. The connection of green frame can be divided into 4 types, depending on its shape, and each type is associated with different characteristics and construction methods. Notably, as the connection between green columns have differing types and sequences of work, subject to the connection method in use, a connection method optimized for relevant site conditions need to be selected. Therefore, this study analyzed pros and cons of 4 different types of green frame connection methods. The results set forth herein will provide basic data for subsequent studies to comparatively analyze the performance and constructibility of different green frame connection methods.

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