• Nutrition Research and Practice
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• v.9 no.1
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• pp.30-36
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• 2015

BACKGROUD/OBEJECTIVES: The mechanism of how black garlic effects lipid metabolism remains unsolved. Therefore, the objectives of this study were to determine the effects of black garlic on lipid profiles and the expression of related genes in rats fed a high fat diet. MATERIALS/METHODS: Thirty-two male Sqrague-Dawley rats aged 4 weeks were randomly divided into four groups (n=8) and fed the following diets for 5 weeks: normal food diet, (NF); a high-fat diet (HF); and a high-fat diet + 0.5% or 1.5% black garlic extract (HFBG0.5 or HFBG1.5). Body weights and blood biochemical parameters, including lipid profiles, and expressions of genes related to lipid metabolism were determined. RESULTS: Significant differences were observed in the final weights between the HFBG1.5 and HF groups. All blood biochemical parameters measured in the HFBG1.5 group showed significantly lower values than those in the HF group. Significant improvements of the plasama lipid profiles as well as fecal excretions of total lipids and triglyceride (TG) were also observed in the HFBG1.5 group, when compared to the HF diet group. There were significant differences in the levels of mRNA of sterol regulatory element binding protein-1c (SREBP-1c), acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and glucose-6-phosphate dehydrogenase (G6PDH) in the HFBG1.5 group compared to the HF group. In addition, the hepatic expression of (HMG-CoA) reductase and Acyl-CoA cholesterol acyltransferase (ACAT) mRNA was also significantly lower than the HF group. CONCLUSIONS: Consumption of black garlic extract lowers SREBP-1C mRNA expression, which causes downregulation of lipid and cholestrol metahbolism. As a result, the blood levels of total lipids, TG, and cholesterol were decreased.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.4C
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• pp.581-593
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• 2004

The interest in wireless LAN security is on the increase owing to a role of high-speed wireless Internet infrastructure of wireless LAN. Wi-Fi has released WPA standard in order to overcome drawbacks of WEP algorithm that is security element of current IEEE 802.11-based wireless LAN system. Pairwise key management and group key management in a mixed-mode which supports both terminals running WPA and terminals running original WEP security are very complicate. In this paper, we analyze flaws in WPA authenticator key management state machine for key distribution and propose the countermeasures to overcome the analyzed problems. Additionally, WPA authenticator key management state machine to which the solutions are applied is described. The reconstructed WPA authenticator key management state machine helps the AP perform efficiently group key exchange and group key update in the mixed-mode.

• The Journal of the Korean dental association
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• v.55 no.5
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• pp.328-338
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• 2017

Introduction: The aim of the current study was to describe the prevalence and treatment of mandibular first molar eruption disturbances. Methods: A total of 38 mandibular first molars(M1mn) from 36 patients(17 males and 19 females; aged 9 years 2 months?35 years 10 months) were identified from the 13,391 patients that received orthodontic treatment from 1983?2012. The subjects were classified into 3 categories based on panoramic radiographic examination: impaction due to ectopic position of the tooth germ relative to the contra-side same tooth(Group 1), impaction due to obstruction of the eruption path with cyst or calcium mass (Group 2), and primary and secondary retention due to defects in the follicle or periodontal ligament(PDL; Group 3). The treatment outcomes were evaluated into four categories: no treatment(A), orthodontic traction(B), autotransplantation(C), and extraction due to orthodontic traction failure(D). Results: The prevalence rate of M1mn eruption disturbances in this sample was 0.27%. In Groups 1 and 2, most of the impacted M1mn were erupted successfully by orthodontic traction. In Group 3, most of the retained M1mn were failed to erupt and recommended for extraction. Conclusions: Treatment prognosis was favorable on Group 1 & 2 than Group 3. After removing an element of the cause in case of Group 1 & 2, orthodontic traction or periodic observation will be recommended.

• Animal Bioscience
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• v.35 no.8
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• pp.1184-1194
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• 2022

Objective: High concentrate diets are widely used to satisfy high-yielding dairy cows; however, long-term feeding of high concentrate diets can cause subacute ruminal acidosis (SARA). The endocrine disturbance is one of the important reasons for metabolic disorders caused by SARA. However, there is no current report about thyroid hormones involved in liver metabolic disorders induced by a high concentrate diet. Methods: In this study, 12 mid-lactating dairy cows were randomly assigned to HC (high concentrate) group (60% concentrate of dry matter, n = 6) and LC (low concentrate) group (40% concentrate of dry matter, n = 6). All cows were slaughtered on the 21st day, and the samples of blood and liver were collected to analyze the blood biochemistry, histological changes, thyroid hormones, and the expression of genes and proteins. Results: Compared with LC group, HC group showed decreased serum triglyceride, free fatty acid, total cholesterol, low-density lipoprotein cholesterol, increased hepatic glycogen, and glucose. For glucose metabolism, the gene and protein expression of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase 1 in the liver were significantly up-regulated in HC group. For lipid metabolism, the expression of sterol regulatory element-binding protein 1, long-chain acyl-CoA synthetase 1, and fatty acid synthase in the liver was decreased in HC group, whereas carnitine palmitoyltransferase 1α and peroxisome proliferator activated receptor α were increased. Serum triiodothyronine, thyroxin, free triiodothyronine (FT3), and hepatic FT3 increased in HC group, accompanied by increased expression of thyroid hormone receptor (THR) in the liver. Conclusion: Taken together, thyroid hormones may increase hepatic gluconeogenesis, β-oxidation and reduce fatty acid synthesis through the THR pathway to participate in the metabolic disorders caused by a high concentrate diet.

• Archives of Pharmacal Research
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• v.15 no.3
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• pp.239-241
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• 1992

The methanol extract of Cinnamoni Cortex showed antibacterial action against cariogenic bacterium, Streptococcus mutans OMZ 176. The active principle of the extract was identified to be trans-cinnamaldehyde, which was bactericidal in the minimal inhibitory concentration (MIC) of $100\;\mu$g/ml against the strain. From the results of antibacterial activity of cinnamaldehyde and its derivatives, the acrolein group in the cinnamaldehyde was elucidated to be an essential element for the activity.

• Journal of applied mathematics & informatics
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• v.7 no.2
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• pp.553-573
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• 2000

In this paper, we consider hyperstructures (H,·) when H={e,a,b}. We put a condition on (H,·) where e is a unit. We obtain minimal and maximal Hv -groups , semigroups and quasigroups , using Mathematical 3.0 computer programs.

• Architectural research
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• v.15 no.4
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• pp.207-214
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• 2013

A form-finding technique is proposed for three-dimensional spatial structures. Two-step discrete finite element (FE) mesh generator based on computer aided geometric design (CAGD) is introduced and used to control the shape of three-dimensional spatial structures. Mathematical programming technique is adopted to search new forms (or shapes) of spatial structures. For this purpose, the strain energy is introduced as the objective function to be minimized and the initial volume (or the initial weight) is considered as constraint function. Numerical examples are carried out to test the capability of the proposed form-finding techniques and provided as benchmark tests.

• JSTS:Journal of Semiconductor Technology and Science
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• v.5 no.1
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• pp.17-23
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• 2005

This paper describes the simulation of a micromachined dome-shaped-diaphragm acoustic transducer built on a $1.5{\mu}m$ thick silicon nitride diaphragm ($2,000{\mu}m$ in radius, with a circular clamped boundary on a silicon substrate) with electrodes and piezoelectric ZnO film in a silicon substrate. Finite element analysis with ANSYS 5.6 has been performed to analyze the static and dynamic behaviors of the transducer under both pressure and voltage loadings.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 1988.10a
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• pp.144-147
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• 1988

대덕망에 Osi 프로토콜을 구현하기 위한 일련의 작업들은 ETRI의 Osi Group 에 의해서 1985년경부터 시작이 되었다. 현재 Osi의 FTAM(File transfer Access and Managenemt) 프로토콜과 ACSE (Association Control Service Element) presentation 계층 session 계층이 상위계층 프로토콜로 구현되었으며, 상위 계층에서 필요한 통신 서비스를 제공하귀 위해서 transport 계층 및 대덕 man의 통신 서비스를 이용하기 위한 intertiace 들이 구혀되었다. 이러한 interface는 순차적으로 jualring optical cable을 control 하여 대덕 man에 위치한 node들 사이에 Osi 상위계층 프로토콜의 서비스를 제공하게 된다.

• Communications of the Korean Mathematical Society
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• v.10 no.3
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• pp.653-659
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• 1995

We prove that two essentially normal elements of a type $II_{\infty}$ factor von Neumann algebra are unitarily equivalent up to the compact ideal if and only if they have the identical essential spectrum and the same index data. Also we calculate the spectrum and essential spectrum of a non-unitary isometry of von Neumann algebra.