• Journal of Marine Bioscience and Biotechnology
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• v.1 no.4
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• pp.225-231
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• 2006

The secondary metabolites from Taiwanese marine soft corals and sponges have attracted much attention because they possess considerable potential biological activities. To explore the origin of bioactivity, many cytotoxic natural products were isolated and characterized in the past few years. For examples, The lipophilic extracts from marine sponges Petrosia elastica and Ircinia formosana were found active against several human tumor cells. The investigation of the gorgonian Junceela has also resulted in the discovery of a series of new juncenolides. Bioassay-directed fractionation of Clavularia viridis yielded seven new prostanoids. These compounds have been tested and evaluated as potential antitumor agents. The soft corals of the genus Cespitularia produced novel secondary metabolites with diverse chemical structures and interesting biological activities. Four new norditerpenoids, designated cespitulactones and cespihypotins were isolated from Cespitularia hypotentaculata. Cespitulactones are novel structures having a bond cleavage between C-10 and C-11. In addition, three novel diterpenes were isolated from C. taeniata and designated cespitulactams A, B and C having a phenylethyl amino side chain.

• Magazine of the Korean Society of Agricultural Engineers
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• v.41 no.1
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• pp.106-114
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• 1999

This paper explores the geometrical non-linear behavior of the simply supported tapered beams subject to the trapezoidal distributed load and end moments. In order to apply the Bernoulli -Euler beam theory to this tapered beam, the bending moment equation on any point of the elastical is obtained by the redistribution of trapezoidal distributed load. On the basis of the bending moment equation and the BErnoulli-Euler beam theory, the differential equations governging the elastical of such beams are derived and solved numerically by using the Runge-Jutta method and the trial and error method. The three kinds of tapered beams (i.e. width, depth and square tapers) are analyzed in this study. The numerical results of non-linear behavior obtained in this study from the simply supported tapered beams are appeared to be quite well according to the results from the reference . As the numerical results, the elastica, the stress resultants and the load-displacement curves are given in the figures.

• Structural Engineering and Mechanics
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• v.22 no.4
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• pp.433-447
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• 2006

The problem of very large deflection of a circular cantilever arc device subjected to inward or outward polar force is studied. An exact elliptic integral solution is derived for the two cases and the results are checked using large displacement finite element analysis via the ANSYS package by performing a new novel modeling simulation technique for this problem. Excellent agreements have been obtained between the exact analytical solution and the numerical approach. From this study, a design chart for engineers is developed to predict the required value for the inward polar force for the device to switch on for a given angle forming the circular arc (${\theta}_o$). This study has several interesting applications in mechanical engineering, integrated circuit technology, nanotechnology and especially in microelectromechanical systems (MEMs) such as a MEM circular device switch subjected to attractive or repulsive magnetic forces due to the attachments of two magnetic poles at the fixed and at the free end of the circular cantilever arc switch device.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.04a
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• pp.107-114
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• 2002

This paper deals with the non-linear analysis of cantilever beams with constant volume. Numerical methods are developed for solving the elastica of cantilever ben subjected to a tip Point load and a tip couple. The linear, parabolic and sinusoidal tapers with the regular polygon cross-section are considered, whose material volume and span length are always held constant. The Runge-Kutta and Regula-Falsi methods, respectively, are used to integrate the governing differential equations and to compute the unknown value of the tip deflection. The numerical results obtained herein are shown in tables and figures. Also the shapes of strongest beams are determined by reading the minimum values form the deflection versus section ratio curves.

• Structural Engineering and Mechanics
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• v.4 no.1
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• pp.49-59
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• 1996

This paper considers large deflection problem of a simply supported beam with variable are length subjected to a point load. The beam has one of its ends hinged and at a fixed distance from this end propped by a frictionless support over which the beam can slide freely. This highly nonlinear flexural problem is solved by elliptic-integral method and shooting-optimization technique, thereby providing independent checks on the new solutions. Because the beam can slide freely over the frictionless support, there is a maximum or critical load which the beam can carry and it is dependent on the position of the load. Interestingly, two possible equilibrium configurations can be obtained for a given load magnitude which is less than the critical value. The maximum arc-length was found to be equal to about 2.19 times the fixed distance between the supports and this value is independent of the load position.

• Animal cells and systems
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• v.10 no.3
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• pp.163-167
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• 2006

Reverse-Phase High-performance Liquid Chromatography (RP-HPLC) based technique is one of the most sensitive techniques to detect the antibiotics present in honey. In the southern part of Tamilnadu, India, majority of the farmlands are occupied by plantations such as coconut, banana and rubber. A variety of antimicrobial compounds and antibiotics, which have been reported in pollen, nectar and other floral parts of the plant, gets accumulated in honey through honeybees (Apis mellifera). We have collected the nectar samples from banana (Musa paridasiaca) and rubber (Ficus elastica) flowers and the honey from honey hives of banana and rubber cultivated areas. The extracted nectar and honey samples are subjected to RP-HPLC analysis with authentic antibiotic standards. Nectar and honey samples showed 4-17, 11-29 ${\mu}g/kg$ of streptomycin, 2-29, 3-44 ${\mu}g/kg$ of ampicillin and 17-34, 26-48 ${\mu}g/kg$ of kanamycin respectively.

• Magazine of the Korean Society of Agricultural Engineers
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• v.42 no.2
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• pp.108-114
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• 2000

This paper explores the non-linear behavior of tapered beam subjected to a floating concentration load. For applying the Bernoulli-Euler beam theory to this beam, the bending moment at any point of elastical is obtained from the final equilibrium stage. By using the bending moment equation and the Bernoulli-Euler beam theory, the differential equations governing the elastica of simple beam are derived , and solved numberically . Three kinds of tapered beam types are considered . The numerical results of the non-linear behavior obtained in this study are agreed quite well to the results obtained from the laboratory-scale experiments.

• Structural Engineering and Mechanics
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• v.19 no.4
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• pp.413-423
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• 2005

This paper presents the solution of large static deflection due to uniformly distributed self weight and the critical or maximum applied uniform loading that a simply supported beam with variable-arc-length can resist. Two analytical approaches are presented and validated experimentally. The first approach is a finite-element discretization of the span length based on the variational formulation, which gives the solution of large static sag deflections for the stable equilibrium case. The second approach is the shooting method based on an elastica theory formulation. This method gives the results of the stable and unstable equilibrium configurations, and the critical uniform loading. Experimental studies were conducted to complement the analytical results for the stable equilibrium case. The measured large static configurations are found to be in good agreement with the two analytical approaches, and the critical uniform self weight obtained experimentally also shows good correlation with the shooting method.

• The Korean Journal of Mycology
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• v.43 no.4
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• pp.231-238
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• 2015

Genome-wide reanalyzed data of 25 Flammulina strains were compared against the reference genome (KACC42780) to establish a genome-wide single nucleotide polymorphism (SNP). The rate of mapping differences between the strains reflected in the strain variation in its result. Genome-wide SNPs distribution divided into types of homozygous SNP and heterozygous SNP moreover all of the strains demonstrated a wide variation in all of the regions. In the further study of topological relationship between the collected strains, phylogenetic tree was separated into 3 major groups. Group I contained F. velutipes var. related strains of ASI 4062, 4148, 4195. Group 2 contained strains that are different species of ASI 4188 F. elastica, ASI 4190 F. fennae, and ASI 4194 F. rossica. The other 19 strains F. velutipes were classified as a single group. However, further experiment to discriminate its genetic relationship between the white group and brown group did not verify its validity. The inferred tree exhibited a phylogenetic relationship between Korea white fruitbody forming strains of ASI 4210, 4166, 4178 and Japan white fruitbody forming strains of ASI 4209, 4167 confirmed to be genetically closely related.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1995.10a
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• pp.185-190
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• 1995

In recent years, many researcher have been interested in the stability of a thin beam. Among them, Pai and Nayfeh[1] had investigated the nonplanar motion of the cantilever beam under lateral base excitation and chaotic motion, but this study is associated with internal resonance, i.e. one to one resonance. Also Cusumano[2] had made an experiment on a thin beam, called Elastica, under bending loads. In this experiment, he had shown that there exists out-of-plane motion, involving the bending and the torsional mode. Pak et al.[3] verified the validity of Cusumano's experimental works theoretically and defined the existence of Non-Local Mode(NLM), which is came out due to the instability of torsional mode and the corresponding aspect of motions by using the Normal Modes. Lee[4] studied on a thin beam under bending loads and investigated the routes to chaos by using forcing amplitude as a control parameter. In this paper, we are interested in the motion of a thin beam under torsional loads. Here the form of force based on the natural forcing function is used. Consequently, it is found that small torsional loads result in instability and in case that the forcing amplitude is increasing gradually, the motion appears in the form of dynamic double potential well, finally leads to complex motion. This phenomenon is investigated through the poincare map and time response. We also check that Harmonic Balance Method(H.B.M.) is a suitable tool to calculate the bifurcated modes.