• Title/Summary/Keyword: Effective normal stress

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A Study on the Image Processing for Effective Insulation Material Degradation Testing (효과적인 절연재료 열화검사를 위한 영상처리에 관한 연구)

  • 정기봉;오무송;김태성
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1999.05a
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    • pp.230-233
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    • 1999
  • Because Insulation material is play an important part for normal work of electricity equipment, the study is advanced, but as the voltage of electricity system is raising, we required that new lnsulation material. They have excellent specific against high stress, namely the study of insulation increase and prevention diagnosis of insulation degradation of Epoxy or XLPE and so on. In this thesis. I utilize image processing technique for effective inspection of insulation material degradation.

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Effects of Hominis Placenta Pharmacopucture in a Chronic Physical Stress Rat Model on Changes in Behavior, Weight, Sleep-Related Hormones, Inflammatory Cytokines, and Anti-Oxidant Enzymes (자하거 약침이 만성 신체 스트레스 모델 백서의 행동, 체중, 수면 호르몬, 염증 사이토카인, 항산화 효소의 변화에 미치는 영향)

  • Ha, Ji-Won;Lee, Yu-Mi;Na, Chang-Su;Sakong, Jong-Won;Kim, Bo-Kyung
    • Journal of Oriental Neuropsychiatry
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    • v.30 no.4
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    • pp.357-369
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    • 2019
  • Objectives: This study was designed to examine the effect of Hominis Placenta Pharmacopuncture on the change in behavior, sleep-related hormones, inflammatory cytokines, anti-oxidants, weight, blood, and serum on rats given chronic physical stress. Methods: Wistar rats older than age 10 weeks were used in this experiment. They were divided into six groups. The normal group was not given stress. The control group was given only chronic physical stress and no treatment. The positive control group was given chronic physical stress and treated with zolpidem. Three Hominis Placenta Pharmacopuncture (HPP) groups were given chronic physical stress, then treated with different concentrations of HPP; HPP-0.5× (0.5 times diluted), HPP-1× (undiluted) and HPP-2× (2 times condensed). The changes of values of Nestlet Shredding results, weight, Melatonin, Gamma-aminobutylic Acid (GABA), Tumor Necrosis Factor Alpha (TNF-α), Interleukin-6 (IL-6), Superoxide dismutase (SOD), glutathione peroxidase (GPx), AST, ALT, BUN, Creatinine, and leukocytes were observed during the experiment. Results: The changes in chronic physical stress of the rat model were as follow. The Nestlet Shredding result increased in the control group compared to the normal group (p<0.05), and decreased in the HPP-1× and HPP-2× compared to the control group (p<0.05). The amount of weight gain showed increasing tendency in the HPP-2× compared to the control group since the second week. The GABA increased (p<0.05) and Melatonin also showed certain increasing tendency in the HPP-1× and HPP-2× compared to the control group. The TNF-α and IL-6 increased in the control group compared to the normal group (p<0.01), and decreased in all the HPPs compared to the control group (p<0.05). The SOD level decreased in the control group compared to the normal group (p<0.01), and increased in all the HPPs compared to the control group (p<0.05). GPx, AST, ALT, Bun, Creatinine and leukocytes showed no noticeable difference among all groups. Conclusions: Hominis Placenta Pharmacopuncture was effective in increasing weight, GABA, Melatonin, SOD, and decreasing Nestlet Shredding and inflammatory cytokines, suggesting that it consequently facilitates in relieving physical stress.

A Meta-Analysis of the meets of Aromatherapy on Psychological Variables in Nursing (아로마테라피 간호중재의 정신심리적 효과 메타분석)

  • Roh, Kook-He;Park, Hyeoun-Ae
    • Research in Community and Public Health Nursing
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    • v.20 no.2
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    • pp.113-122
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    • 2009
  • Purpose: The purpose of this study is to explore the effect of aromatherapy on anxiety, depression, and stress. Methods:Medical and nursing literature databases were searched to identify studies comparing aromatherapy with a control group. Results: Thirty-one studies published till September 2008 were included in the analysis. Twenty-two studies showed that aromatherapy generally had positive effects on the anxiety level (ES: 0.61). Thirteen studies showed that aromatherapy has significantly decreased the depression level (ES: 0.91). Seven studies showed that aromatherapy had positive effect on the stress level (ES: 0.78). Further analysis found that aromatherapy was more effective for normal population than for patients group with anxiety and stress. On the contrary, aromatherapy was more effective for patients group than for general population with depression. Conclusion: Aromatherapy had positive effect on anxiety, depression and stress level. But there was no sufficient evidence to show the two different aromatherapy methods and two different period of aromatherapy had different effects due to small sample size and heterogeneity of sample. And it was needed to perform follow-up and further comparative studies.

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Genome Wide Expression Analysis of the Effect of Pinelliae Rhizoma Extract on Psychological Stress (반하(半夏)가 스트레스로 인한 생쥐의 뇌조직 유전자변화에 미치는 영향 연구)

  • Jeong, Jong-Hyo;Cho, Su-In;Song, Young-Gil;Kim, Ha-Na;Kim, Kyeong-Ok
    • Journal of Oriental Neuropsychiatry
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    • v.26 no.1
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    • pp.63-78
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    • 2015
  • Objectives: Pinelliae Rhizoma has traditionally been used as an anti-depressant in oriental medicine. This study is to investigate the effect of Pinelliae Rhizoma extract (PRe) on psychological stress in genome wild expression of mice. Methods: After giving physical stress to mice, PRe was orally administered with 100 mg/kg/day for five days. After extracting whole brain tissue from the mice, their genome changes were observed by micorarray analysis method. The genome changes were analyzed by IMAGENE 4.0, TREEVIEW, FatiGo algorithems, BOND database, cytoscape program, etc. Results: 1. PRe administered group were remained at normal level; 60% of increase was shown in expressed genes by physical stress, and 65% of decrease was shown in expressed genes by psychological stress. 2. Genes with increased expression in control group that remained at a normal state in PRe administered group were involved with the gene of a cellular metabolic process on biological process, protein binding on molecular function, and cell part on cell composition. The pathway was found to be cytokin-cytokin receptor interaction. 3. Genes with decreased expression in control group that remained at a normal state in PRe administered group were involved with the gene of a cellular metabolic process on biologiacl detail and coupled ATPaes activity on molecular function. This gene related path was Ubiquintin mediated proteolysis etc. 4. Core node genes analyzed by protein interaction network were Vinculin, Cell sdivision cycle 42 homolog (S. cerevisiae) etc. They played an important role in maintaining cytoskeleton and controlling cell cycle. Conclusions: Several genes were up-regulated and down-regulated in response to psychological stress. The expression of most of the genes that were altered in response to psychological stress was restored to normal levels in PRe treated mice. When the interaction network information was analyzed, the recovery of the core node genes in PRe treated mice indicates that this final set of genes may be the effective target of PRe.

Stress Analysis of Cold-Formed Steel Beams Considering Local Buckling Effects (국부좌굴을 고려한 냉간성형 ㄷ 형강보의 응력해석)

  • Jeon, Jae Man;Hyun, Ja Young;Lee, Jae Hong
    • Journal of Korean Society of Steel Construction
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    • v.16 no.1 s.68
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    • pp.51-60
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    • 2004
  • The stress analysis of cold-formed channel section steel beams under transverse load was conducted. The local buckling effect was included in the analysis using effective area concept. The proposed analytical model is capable of predicting accurate normal stress in the beam due to various behaviors including biaxial bending and warping. It was found to be appropriate for predicting stresses as well as deflection in the beam. A finite element model was developed to solve the analytical model.

Anti-stress Effects of Nelumbo nucifera in ICR Mice

  • Kim, Young-Ock;Noh, Huyng-Jun;Lee, Ji-Hyun;Kim, Hyung-Don
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2010.05a
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    • pp.4-4
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    • 2010
  • The aim of this study is to investigate anti-stress effect of Nelumbo nucifera extract (NNE) inimmobilization - stressed ICR mice. Stress exposure has induced adrenal gland weight, plasma glucose and level in NNE. The experiments were performed with the use of 9 weeks of age male ICR mice (20-25g) at the time of first treatment with NNE. Animals of the normal group were not exposed to any stress and the control group were exposed to stress. The rats of NNE and Diazepam (BZ) supplementary group were orally administered once a day, 100 mg of NNE, 5 mg of BZ extract/kg body weight and they were exposed to stress. Animals were given supplements for 7 days without stress, and then were given supplements for 5 days with restraining. NNE was effective in decreasing scopolamine induced deficit in passive avoidance test and levels of blood corticosterone which was increased by stress in the mice.

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Dynamic simulation of squeezing flow of ER fluids using parallel processing

  • Kim, Do-Hoon;Chu, Sang-Hyon;Ahn, Kyung-Hyun;Lee, Seung-Jong
    • Korea-Australia Rheology Journal
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    • v.11 no.3
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    • pp.233-240
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    • 1999
  • In order to understand the flow behavior of Electrorheological (ER) fluid, dynamic simulation has been intensively performed for the last decade. When the shear flow is applied, it is easy to carry out the simulation with relatively small number of particles because of the periodic boundary condition. For the squeezing flow, however, it is not easy to apply the periodic boundary condition, and the number of particles needs to be increased to simulate the ER system more realistically. For this reason, the simulation of ER fluid under squeezing flow has been mostly performed with some representative chains or with the approximation that severely restricts the flow geometry to reduce the computational load. In this study, Message Passing Interface (MPI), which is one of the most widely-used parallel processing techniques, has been employed in a dynamic simulation of ER fluid under squeezing flow. As the number of particles used in the simulation could be increased significantly, full domain between the electrodes has been covered. The numerical treatment or the approximation used to reduce the computational load has been evaluated for its validity, and was found to be quite effective. As the number of particles is increased, the fluctuation of the normal stress becomes diminished and the prediction in general was found to be qualitatively In good agreement with the experimental results.

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Antioxidant Effect of Annexin A-1 Induced by Low-dose Ionizing Radiation in Adipose-derived Stem Cells

  • You, Ji-Eun;Lee, Seung-Wan;Kim, Keun-Sik;Kim, Pyung-Hwan
    • Biomedical Science Letters
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    • v.26 no.4
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    • pp.249-255
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    • 2020
  • Radiation therapy is one of the primary options for the treatment of malignant tumors. Even though it is an effective anti-cancer treatment, it can cause serious complications owing to radiation-induced damage to the normal tissue around the tumor. It was recently reported that normal stem cell response to the genotoxic stress of ionizing radiation can boost the therapeutic effectiveness of radiation by repairing damaged cells. Therefore, we focused on annexin A-1 (ANXA1), one of the genes induced by low-dose irradiation, and assessed whether it can protect adipose-derived stem cells (ADSCs) against oxidative stress-induced damage caused by low-dose irradiation and improve effectively cell survival. After confirming ANXA1 expression in ADSCs transfected with an ANXA1 expression vector, exposure to hydrogen peroxide (H2O2) was used to mimic cellular damage induced by a chronic oxidative environment to assess cell survival under oxidative conditions. ANXA1-transfected ADSCs demonstrated that increased viability compared with un-transfected cells and exhibited enhanced anti-oxidative properties. Taken together, these results suggest that ANXA1 could be used as a potential therapeutic target to improve the survival of stem cells after low-dose radiation treatment.

Experimental Study on the Antidepressant Effect of Sam-Jeong-Hwan (삼정환(三精九)의 항우울 효과에 대한 실험적 연구)

  • Lee, Sang-Taek;Kim, Geun-Woo;Koo, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.19 no.3
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    • pp.101-115
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    • 2008
  • Objective: The purpose of this study was to investigate the protective effects of Sam-Jeong-Hwan(SJH) on the animal model of depression induced immobilization stress. Method: The subject were divided into 4 groups(l. normal 2. saline solution administered during immobilization stress treatment 3. SJH of 100mg/kg administered 4. BKJ of 400mg/kg administered). Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone and ACTH in blood were measured. Results: In forced swimming test, SJH of 400mg/kg group showed decreased immobilization. In passive avoidance test, SJH of 400mg/kg group showed increased learning execution. In EPM test, SJH of 400mg/kg group showed decreased anxiety. In locomotor activity test, SJH groups showed significantly increased locomotor activity. Stress group showed significantly increase in serum level of corticosterone, SJH of 400mg/kg group showed decreased serum level of corticosterone. Stress group showed significantly increase in serum level of ACTH, SJH of 400mg/kg group showed decreased serum level of ACTH. Conclusion: These results suggest that Sam-Jeong-Hwan(SJH) is effective in the treatment of depression.

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A Proposal of Parameter to Predict Biaxial Fatigue Life for CF8M Cast Stainless Steels (CF8M 주조 스테인리스강의 2축 피로수명 예측을 위한 파라미터의 제안)

  • Park Joong Cheul;Kwon Jae Do
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.29 no.6 s.237
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    • pp.815-821
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    • 2005
  • Biaxial low cycle fatigue test was carried out to predict fatigue life under combined axial-torsional-loading condition which is that of in-phase and out-of-phase for CF8M cast stainless steels. Fatemi-Socie(FS) parameter which is based on critical plane approach is not only one of methods but also the best method that can predict fatigue life under biaxial loading condition. But the result showed that, biaxial fatigue life prediction by using FS parameter with several different parameters for the CF8M cast stainless steels is not conservative but best results. So in this present research, we proposed new fatigue life prediction parameter considering effective shear stress instead of FS parameter which considers the maximum normal stress acting on maximum shear strain and its effectiveness was verified.