• Microbiology and Biotechnology Letters
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• v.20 no.4
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• pp.445-450
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• 1992

An enhancement of the oxygen transfer rate in a 1$\ell$ bioreactor for mammalian cell culture by using a silicone rubber tubing as an oxygenator was investigated. When the silicone membrane was used to supply oxygen to the culture broth, the oxygen transfer coefficients ($k_{\iota}a$) measured in deionized-distilled water were markedly increased. Effect of surface aeration without the tubing aeration was very low under $1.0hr^{-1}$ of $k_{\iota}a$. The enhancing effects of agitation rates on $k_{\iota}a$ were much more effective than those of aeration rates. The increase of $k_{\iota}a$ with increasing tube length was observed as a result of the large surface area for oxygen supply. However, 2 m of the tube length was adequate for a 1$\ell$ vessel. The larger blade type of impeller was effective to enhance the kLa values because of its high mixing intensity. In culture medium supplemented with 5% serum, kLa values were reduced to approximately 40% probably due to the viscosity. We also obtained the normal cell concentration of $5{\times}10^6$ cells/m$\ell$ of HepG2 on microcarriers, which could be achieved in a typical bioreactor for animal cell culture.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.40 no.5
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• pp.312-320
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• 2003

This work describes an 8b 200 MHz 0.18 urn CMOS analog-to-digital converter (ADC) based on a pipelined architecture for flat panel display applications. The proposed ABC employs an improved bootstrapping technique to obtain wider input bandwidth than the sampling tate of 200 MHz. The bootstrapuing technique improves the accuracy of the input sample-and-hold amplifier (SHA) and the fast fourier transform (FFT) analysis of the SHA outputs shows the 7.2 effective number of bits with an input sinusoidal wave frequency of 500 MHz and the sampling clock of 200 MHz at a 1.7 V supply voltage. Merged-capacitor switching (MCS) technique increases the sampling rate of the ADC by reducing the number of capacitors required in conventional ADC's by 50 % and minimizes chip area simultaneously. The simulated ADC in a 0.18 um n-well single-poly quad-metal CMOS technology shows an 8b resolution and a 73 mW power dissipation at a 200 MHz sampling clock and a 1.7 V supply voltage.

• Management & Information Systems Review
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• v.36 no.2
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• pp.1-20
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• 2017

SCM system is a strategic cooperative that organically integrates all supply chains to improve the performance of a company. For effective SCM system, emphasis is placed on securing long-term, mutual relationships and change management. The implementation of an SCM system is likely to introduce a wide range of changes in and across member organizations and these changes are likely to be met with scepticism and resistance by individuals and organizations in the chain. Thus, the success of an SCM system cannot be guaranteed without effective change management. And we adopted the concept of information orientation (IO) as our method to measure the performance of an SCM system through information quality and information sharing. Therefore, this study examined the influence of mutual, reciprocal relationships among change management on information capability through information quality and information Sharing. The results of this study can be summarized as follows. First, change management had a significant influence on information quality, information Sharing and information capability. Second, information quality had a significant influence on information Sharing and information capability. Third, information sharing had a significant influence on information capability.

• Journal of Korea Water Resources Association
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• v.37 no.10
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• pp.789-798
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• 2004

Conjunctive use of surface and ground water is emerging as an alternative to resolve water shortage problems caused by drought or overpopulation. The region whose water supply depends on a single source has high risk of emergency situations, and may need to consider conjunctive use to overcome its weakness. Conjunctive use also can be a realistic and effective solution when additional or new water resources are to be developed. This paper presents a new methodology for managing surface and ground water resources with the aim of supplying water in a sustainable way. The developed method encompasses procedures to assess site suitability for conjunctive use, to devise water supply scenarios based on drought analysis, and to quantify the amount of water attained. It is believed that the systematic and objective features of the developed method enable it to be a useful supportive tool for water management planning and decision-making.

• Journal of the FoodService Safety
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• v.2 no.2
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• pp.67-77
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• 2021

Concerns regarding work and food safety in foodservice operations are growing. The purpose of the study is to suggest guidelines for designing foodservice facilities, including school foodservices and Korean restaurants. A case of a franchise restaurant specializing in a Korean food item, Seolleongtang, was used to explain the facility design. The contents of the manual included ways to determine space allocation, calculate the application of utilities and the diameters of supply utility pipelines, and suggestions on how to decide on air conditioning equipment. The standards of the American Gas Association and the Japan Foodservice Equipment Association (JFEA) were applied to design the restaurant space. The JFEA standards and knowledge based on experience and statistics were applied to calculate the usage of utilities like fuel and water. The standards of JFEA and the Society of Heating, Air-Conditioning, and Sanitary Engineers of Japan were applied to calculate the diameters of the water supply and drainage pipelines. For the setting of the heating, ventilation, and air conditioning systems, three ways to carry out the calculation of effective ventilation were explained, as well as options to dicide the standard parameters of the duct and ventilation fans. This manual can contribute to the design of effective and efficient foodservice facilities and help secure the work safety of foodservice employees thereby ensuring food safety.

• Journal of Korea Society of Digital Industry and Information Management
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• v.11 no.1
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• pp.121-133
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• 2015

IoT utilized network vitalization between objects are being rapidly established within current IT communication environment. Therefore the worth of smart mirrors is rising for it is a tool to allow online network between objects to be possible in human communication environment. For effective IoT generation's communication, this research intends to evaluate the smart mirror's value for practical uses based on the users' experiences. For the UX evaluation according to the locations where it will be used, Peter Morville's Honeycomb model and Jocob Nielsen's usage evaluation principles were referred to analyze effectiveness of 4 factors, utilization convenience, communication effectiveness, mass interest and space adequateness on households, public places and work places. Hence, we have were led to an objective result through statistical analysis method based on survey. As a result, we have confirmed the smart mirror's positive influence on the users' effective communication in all places. Especially in households, utilization convenience and space adequateness appeared to be high that confirmed sufficient users' need for the home-automation services. In public places, the communication effectiveness and space adequateness ranked high to confirm that the smart mirror utilization is adequate to provide location information. Also, in work places, the mass adequateness was high that we were able to confirm that supply of work place-specific service contents would bring meaningful results to the users. The smart mirrors are the adequate method to provide effective communication in IoT generation with high possibilities in further development.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.20 no.8
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• pp.547-555
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• 2008

The effects of paper properties such as density, air permeability, water vapor transmission rate on the thermal performance of plate-type enthalpy exchanger were experimentally investigated. Papers having different properties were made from the same pulp by calendering or refining. Enthalpy exchanger samples were made from the papers, and were tested according to the standard test procedure (KS B 6879). Effective efficiencies were obtained, which accounted for the air leakage between supply and exhaust streams. Results showed that paper density affected the sensible heat transfer of the samples. Sensible heat transfer increased with density of the paper. It was also shown that effective efficiency of latent heat transfer was approximately the same independent of the samples, which suggests that papers made of the same pulp show similar water vapor transmission characteristics independent of the degree of calendering or refining. Best performance was obtained for the sample having highest paper density and moderate water vapor transmission ratio.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.4
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• pp.253-260
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• 2021

Organ transplantation is currently the most fundamental treatment for organ failure, but there is a shortage of organ supply compared to those in need. Regenerative medicine has recently developed a decellularization technique that overcomes the limitations of conventional organ transplantation and attempts to reconstruct damaged tissues or organs to their normal state. Several decellularization methods have been suggested. In this experiment, the decellularization methods were used to find effective decellularization methods for humanlike porcine placenta. The optimal conditions for decellular support are low DNA content and high glycos amino glycans (GAGs) and collagen content. In order to satisfy this condition, SDS and Triton X-100 and SDS + Triton X-100 were used as the detergent used for decellularization in this experiment. The contents were compared according to the decellularization time (0, 12, 24, 48 and 72 hours), and the concentrations of SDS (0.2, 0.5, 0.7 and 1.0%) were mixed in 1.0% Triton X-100 to analyze the contents. When decellularized using SDS and Triton X-100, respectively, it was confirmed that the contents of DNA and GAGs were opposite to each other. And decellularization treatment for 24 hours at 0.5% SDS was able to obtain an effective decellular support. If decellularization studies of various detergents can be obtained an effective decellular support, and furthermore, cell culture experiments can confirm the effect on the cells.

• Journal of Animal Reproduction and Biotechnology
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• v.38 no.1
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• pp.10-16
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• 2023

Intermuscular fat is essential for enhancing the flavor and texture of cultured meat. Mesenchymal stem cells derived from intermuscular adipose tissues are a source of intermuscular fat. Therefore, as a step towards developing a platform to derive intermuscular fat from mesenchymal stem cells (MSCs) for insertion between myofibrils in cultured beef, an advanced protocol of intermuscular adipose tissue dissociation effective to the isolation of MSCs from intermuscular adipose tissues was developed in cattle. To accomplish this, physical steps were added to the enzymatic dissociation of intermuscular adipose tissues, and the MSCs were established from primary cells dissociated with physical step-free and step-added enzymatic dissociation protocols. The application of a physical step (intensive shaking up) at 5 minutes intervals during enzymatic dissociation resulted in the greatest number of primary cells derived from intermuscular adipose tissues, showed effective formation of colony forming units-fibroblasts (CFU-Fs) from the retrieved primary cells, and generated MSCs with no increase in doubling time. Thus, this protocol will contribute to the stable supply of good quality adipose-derived mesenchymal stem cells (ADMSCs) as a fat source for the production of marbled cultured beef.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.49 no.4
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• pp.195-198
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• 2000

This paper illustrates a new method for constructing composite power system effective load duration curve(CMELDC) at load points. The main concept of proposed method is that the CMELDC can be obtain from convolution integral processing of the outage probabilistic distribution function of not supplied power and the load duration curve given at each load point. The effective load duration curve (ELDC) at HLI plays an important part in probabilistic production simulation, reliability evaluation, outage cost assessment and power supply margins assesment for power system planning and operation. And also, the CMELDC at HLII will extend the application areas of outage cost assessment and reliability evaluation at each load point. The CMELDC at load points using the Monte Carlo method and a DC load flow constrained LP have already been developed by authors. The effective load concept at HLII, however, has not been introduced sufficiently in last paper although the concept is important. In this paper, the main concept of the effective load at HLII which is proposed in this study is defined in details as the summation of the original load and the probabilistic loads caused by the forced outage of generators and transmission lines at this load point. The outage capacity probabilistic distribution function at HLII can be obtained by combining the not supplied powers and the probabilities of the not supplied powers at this load point. It si also expected that the proposed CMELDC can be applied usefully to research areas such as reliability evaluation, probabilistic production cost simulation and analytical outage cost assessment, etc. at HLII in future. The characteristics and effectiveness of this methodology are illustrated by case study of IEEE-RTS.