• 한국융합학회논문지
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• 제10권3호
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• pp.135-140
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• 2019

본 연구는 가상환경 기반 VR(가상환경)과 실사 환경 기반 VR 중심으로 콘텐츠의 환경에서 사이버 멀미 요인을 분석하는 데 목적이 있다. 1차로 문헌연구를 통해 사이버 멀미의 원인을 규명하기 위해 3D 애니메이션과 다큐멘터리에 관한 이론을 정리하였다. 멀미 정도에 대한 측정 도구로써는 표준화된 SSQ(Simulator Sickness Questionnaire) 설문지를 활용하여 증상 값을 측정하였다. 측정 후에는 SSQ 설문지를 바탕으로 심층 인터뷰를 진행하였다. 연구 결과는 첫째, 가상환경 기반 VR보다는 실사 환경 기반 VR의 콘텐츠가 사이버 멀미를 유발한다, 둘째, VR 콘텐츠는 강한 채도 값이 사이버 멀미를 유발한다. 본 연구는 VR 초기 콘텐츠를 구성하는데 디자인 가이드라인으로 활용할 수 있으며, 사이버 멀미 연구에 활용할 수 있을 것으로 기대한다.

• Annals of Clinical Neurophysiology
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• 제21권1호
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• pp.36-43
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• 2019

Background: Diabetic peripheral polyneuropathy (DPN) is associated with a variety of symptoms. Nerve conduction studies (NCSs) are considered to be the gold standard of nerve damage assessments, but these studies are often dissociated from the subjective symptoms observed in DPN patients. Thus, the aim of the present study was to investigate the correlations between NCS parameters and neuropathic symptoms quantified using the Michigan Neuropathy Screening Instrument (MNSI). Methods: Patients with type 2 diabetes mellitus (T2DM) with or without symptoms of neuropathy were retrospectively enrolled. Demographic data, clinical laboratory data, MNSI score, and NCS results were collected for analysis; DPN was diagnosed based on the MNSI score (${\geq}3.0$) and abnormal NCS results. Pearson's correlation coefficients were used to evaluate the relationships between MNSI score and NCS variables. Results: The final analyses included 198 patients (115 men and 83 women) with a mean age of $62.6{\pm}12.7$ years and a mean duration of diabetes of $12.7{\pm}8.4$ years. The mean MNSI score was 2.8 (range, 0.0-9.0), and 69 patients (34.8%) were diagnosed with DPN. The MNSI score was positively correlated with the median motor nerve latency and negatively correlated with the median motor, ulnar sensory, peroneal, tibial, and sural nerve conduction velocities (NCVs). When the patients were categorized into quartiles according to MNSI score, peroneal nerve conduction velocity was significantly lower in the second MNSI quartile than in the first MNSI quartile (p = 0.001). A multivariate analysis revealed that the peroneal NCV was independently associated with MNSI score after adjusting for age, sex, and glycosylated hemoglobin A1c (HbA1c) levels. Conclusions: The present results indicate that a decrease in peroneal NCV was responsible for early sensory deficits in T2DM patients.

• 사상체질의학회지
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• 제31권1호
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• pp.65-78
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• 2019

Objectives This study aims to investigate how the Korean disease-related vocabulary is established or changed when it is translated into French or English. Through this, we examine changes in the meaning of diseases and the ecosystem of disease-related vocabulary in transition period of $19^{th}$ to $20^{th}$ century. Methods Korean disease-related vocabulary are extracted from a total of 148,000 Korean headwords included in our corpus of three bilingual dictionaries. Among them, the scope of analyisis is limited to group of vocabularies that include a high frequency words, disease(病) and symptom(症). Results The first type of change is the emergence of a neologism. In this case, coexistence of existing vocabulary and new words is observed. The second change is the appearance of loan words written in Hangul. The third is the case where the interpretation of meaning is changed while maintaining the word form. Finally, the fourth change is that the orthographic variants are displayed while maintaining the meaning of the existing vocabulary. Discussion Disease-related vocabulary increased greatly between 1897 and 1931. The increasing factor of vocabulary was the emergence of coined words, compound words and the influx of foreign words. The Korean language and the Western language made a new lexical form in order to introduce a new unknown concept to the Korean. We could also confirm that the way in which English word expanded its semantic field by modifying the way of representing the meaning of Korean Disease-related vocabulary.

• 한국융합학회논문지
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• 제13권4호
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• pp.71-78
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• 2022

파킨슨병은 임상적으로 인지 및 신경정신과 증상을 포함한 다양한 운동 및 비운동 증상으로 특징지어진다. 이러한 다양한 증상을 통합하여 임상적 하위유형(clinical subtype)으로 분류하는 것은 초기 치료 개입에 유용할 수 있다. 본 연구에서는 치매로 진단받지 않은 파킨슨병 환자의 운동, 인지, 신경정신증상과의 상관관계 패턴을 확인하고자 한다. 파킨슨병으로 진단받은 104명의 환자에게 운동 및 인지기능 검사와 신경정신증상에 대하여 종합적인 평가를 시행하였다. 인구통계학적 요인과 운동, 인지, 신경정신증상을 포함한 변수 사이의 상관관계를 확인하고 임상적 하위유형을 추출하기 위하여 요인분석을 실시하였다. 분석결과 1개의 운동관련 요인과 3개의 인지관련 요인 및 4개의 신경정신과적 요인이 추출되었다. 본 연구결과 상관관계의 특성이 파킨슨병의 질병과정에서 특징적인 동반증상 패턴을 가질 수 있음을 확인하였으며, 이를 통해 향후 하위유형을 확인하고 치료적 전략을 수립하는데 유용할 수 있을 것으로 사료된다.

• The Korean Journal of Pain
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• 제35권4호
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• pp.468-474
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• 2022

Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate prolonged musculoskeletal pain as a symptom of the post-COVID-19 condition. Methods: This is a descriptive study on the patients who were diagnosed with COVID-19 in a university hospital, between March 2020 and March 2021. Patient records and an extensive questionnaire were used to obtain relevant demographic and clinical characteristics, including hospitalization history, comorbidities, smoking history, duration of the pain, the area of pain, and the presence of accompanying neuropathic symptoms. Results: Of the diagnosed patients, 501 agreed to participate in the study. Among the participants, 318 had musculoskeletal pain during COVID-19 infection, and 69 of them reported prolonged pain symptoms as part of their a post-COVID condition which could not be attributed to any other cause. The mean duration of pain was 4.38 ± 1.73 months, and the mean pain level was 7.2 ± 4.3. Neuropathic pain symptoms such as burning sensation (n = 16, 23.2%), numbness (n = 15, 21.7%), tingling (n = 10, 14.5%), stinging (n = 4, 5.8%), freezing (n = 1, 1.4%) were accompanied in patients with prolonged musculoskeletal pain. Conclusions: Patients with COVID-19 may develop prolonged musculoskeletal pain. In some patients, neuropathic pain accompanies it. Awareness of prolonged post-COVID-19 pain is crucial for its early detection and management.

• 한국음향학회지
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• 제41권3호
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• pp.367-374
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• 2022

본 논문은 항정신병 약물의 복용량에 따른 음성 특징의 상관관계 분석을 수행하였다. 항정신병 약물의 대표적 부작용 중 하나인 추체외로 증상(ExtraPyramidal Symptoms, EPS) 발생에 따른 음성 특징의 패턴을 알아보기 위하여, 문장 개발을 통해 한국어 기반 추체외로 증상 음성 코퍼스를 구축하였다. 수집된 자료는 추체외로 증상 군과 비 추체외로 증상 군으로 나누어 음성 특징 패턴을 조사하였으며, 특히 추체외로 증상 군의 높은 음성 특징 상관관계를 보였다. 또한, 발화 문장의 종류가 음성 특징 패턴에 영향을 미친다는 것을 확인할 수 있었으며, 이를 통해 음성 특징을 기반한 추체외로 증상의 조기 발견 가능성을 기대해볼 수 있었다.

• 한국작물학회지
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• 제26권1호
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• pp.40-44
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• 1981

답잡초 돌피 외 19종을 대상으로 병원균군, 접종방법 및 잡율의 생육시기를 달리하여 벼흰빛잎마름병의 기주범국 구명시험에서 얻어진 결과를 요약하면 다음과 같다. 1. 나도겨풀, 강아지풀, 독새풀 등은 밀양 2003에 준한 이병성을 나타냈으며, 그 밖에 바랭이, 왕바램이 알방동산이, 너도방동산이, 바람하늘지기 등에서 이병성을 보였으나 광엽잡초에는 전혀 이병되지 않았다. 2. 생육초기에 이병성을 크게 보인 강아지풀, 나도겨풀, 독새풀은 생육전기간을 통해서 이병성이 컸으며, 균군간에는 제일군이 병원성이 다소 큰 것 같았다. 3. 접종방법별로는 유상접종인 핀 및 가위 접종이 무상접종의 분무접종보다 이병성이 켰다.

• Journal of Hospice and Palliative Care
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• 제26권2호
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• pp.51-59
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• 2023

Purpose: We evaluated the status of patients enrolled in South Korea's pediatric palliative care pilot project based on the experience of a single center. This study examined factors related to end-of-life services and differences in medical costs. Methods: The medical records of 120 patients referred by a pediatric palliative care team were analyzed retrospectively. Data from July 1 to February 28, 2022 were collected and analyzed using the chi-square test and the Mann-Whitney U test. Results: Volunteer programs and psychological support (100%), family support and education (99.2%), and financial support through institutional linkage (62.5%) were provided to the participants. In the deceased group, there were no significant differences in general characteristics, which included age, gender, primary disease, religion, duration of hospitalization in an intensive care unit (ICU) and non-intensive care unit (non-ICU). However, the ICU group had fewer opportunities to access individual pain and physical symptom management than the non-ICU group and there were limitations in linking with external resources. Medical expenses were significantly different for the ICU group, with a 3-times higher average cost than the non-ICU group. Conclusion: Although an individualized approach is needed for each patient in pediatric palliative care, psychosocial care is essential. In addition, if early intervention for end-of-life pediatric patients is available from a palliative care team, the cost burden of medical care for patients and their families should be minimal.

• 농촌의학ㆍ지역보건
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• 제48권1호
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• pp.1-12
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• 2023

Objective: The purpose of this study was to identify factors associated with subjective memory impairment in patients with diabetes mellitus in a metropolitan city. Methods: The subjects of this study were 351 patients with diabetes mellitus aged 50 and over from five districts of Gwangju who participated in the 2018 Community Health Survey. We analyzed general characteristics, health-related behaviors and health related conditions and subjective experience of memory impairment. To find factors associated with subjective memory impairment, the chi-square test and multiple logistic regression analysis were used. Results: Of all subjects, 31.3% was reported subjective experience of memory impairment. The odds ratios (ORs; 95% confidence interval (CI)) for subjective memory impairment according to age were statistically significant at 1.9 (0.9-4.3) in patients in 60s and 2.2 (1.1-4.7) in patients in beyond 70s compared to those in 50s. The OR (95% CI) of ex-smoker compared to the non-smoker was 0.3 (0.8-0.9). The OR (95% CI) of depressive symptom compared to no depressive symptoms was 4.9 (95% CI: 1.8-13.7). Conclusion: In this study, subjective memory impairment in patients with diabets mellitus was associated with age, smoking, and depressive symptoms. Based on the results of this study, subjective memory impairment should be detected early through periodic cognitive function evaluation for elderly patients with diabetes mellitus, and a program for healthy cognitive function should be included in diabetes management program.

• Imaging Science in Dentistry
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• 제53권2호
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• pp.117-126
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• 2023

Purpose: Odontomas represent a common clinical entity among odontogenic tumors, but are not well-addressed in the Vietnamese population. The present study aimed to determine the clinical and preclinical characteristics of odontomas and associated factors in the Vietnamese population. Materials and Methods: This retrospective study retrieved data from histopathological diagnoses from 2 central hospitals of Odonto-Stomatology in Ho Chi Minh City, Vietnam during 2004-2017. The odontomas were classified as complex (CxOD) or compound (CpOD) subtypes. The epidemiological, clinical, and radiological characteristics of the odontomas, stratified by subtype and sex, were obtained and analyzed. Results: Ninety cases, consisting of 46 CxODs and 44 CpODs, were included. The average age of patients was 32.4 (±20.2) years. The patients with CxOD were older than those with CpOD (P<0.05). Clinically, 67% of patients showed an intraoral bone expansion. Approximately 60% of patients with CxOD exhibited a painful symptom, about 3-fold more than those with CpOD (P<0.05), whereas almost all patients with CpOD exhibited perturbations of dentition, unlike those with CxOD (P<0.05). Radiologically, CxOD was characterized by a larger dimension than CpOD in both sexes (P<0.05), and CpOD induced complications in adjacent teeth more often than CxOD (P<0.05). The development of odontoma with advancing age differed significantly in odontoma subtypes related to their pathological origins, and between the sexes, resulting from different physiological states. Conclusion: The findings of this study highlight the value of clinical and radiological features of odontomas and their associated factors for the early diagnosis and adequate treatment of younger patients.