Journal of agricultural medicine and community health (농촌의학ㆍ지역보건)

Korean Society for Rural Medicine and Community Health (한국농촌의학지역보건학회)
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Factors Associated with Subjective Memory Impairment in Patients with Diabetes Mellitus in a Metropolitan City

일 광역시 당뇨병 환자의 주관적 기억력 장애 관련 요인

  • Monica Park (Department of Public Health, Graduate School of Health Science, Chosun University) ;
  • So Yeon Ryu (Department of Preventive Medicine, Chosun University Medical School) ;
  • Sung Woo Choi (Department of Preventive Medicine, Chosun University Medical School) ;
  • Jong Park (Department of Preventive Medicine, Chosun University Medical School)
  • 박모니카 (조선대학교 보건대학원 보건학과) ;
  • 류소연 (조선대학교 의과대학 예방의학교실) ;
  • 최성우 (조선대학교 의과대학 예방의학교실) ;
  • 박종 (조선대학교 의과대학 예방의학교실)
  • Received : 2022.10.17
  • Accepted : 2023.01.12
  • Published : 2023.03.31
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Abstract

Objective: The purpose of this study was to identify factors associated with subjective memory impairment in patients with diabetes mellitus in a metropolitan city. Methods: The subjects of this study were 351 patients with diabetes mellitus aged 50 and over from five districts of Gwangju who participated in the 2018 Community Health Survey. We analyzed general characteristics, health-related behaviors and health related conditions and subjective experience of memory impairment. To find factors associated with subjective memory impairment, the chi-square test and multiple logistic regression analysis were used. Results: Of all subjects, 31.3% was reported subjective experience of memory impairment. The odds ratios (ORs; 95% confidence interval (CI)) for subjective memory impairment according to age were statistically significant at 1.9 (0.9-4.3) in patients in 60s and 2.2 (1.1-4.7) in patients in beyond 70s compared to those in 50s. The OR (95% CI) of ex-smoker compared to the non-smoker was 0.3 (0.8-0.9). The OR (95% CI) of depressive symptom compared to no depressive symptoms was 4.9 (95% CI: 1.8-13.7). Conclusion: In this study, subjective memory impairment in patients with diabets mellitus was associated with age, smoking, and depressive symptoms. Based on the results of this study, subjective memory impairment should be detected early through periodic cognitive function evaluation for elderly patients with diabetes mellitus, and a program for healthy cognitive function should be included in diabetes management program.

Keywords

References

  1. Kahn SE, Cooper ME, Del Prato S. Pathophysiology and treatment of type 2 diabetes. perspectives on the past, present and future. Lancet 2014;383(9922);1068-1083 https://doi.org/10.1016/S0140-6736(13)62154-6
  2. Korea Disease Control and Prevention Agency (KDCA). Korea Health Statistics 2020: Korea National Health and Nutrition Examination Survey (KNHANES VIII-2). Cheongju: Korea Disease Control and Prevention Agency [cited 2022 September 19]. Available at https://knhanes.kdca.go.kr/knhanes/sub04/sub04_04_01.do (Korean)
  3. Yuan XY, Waang XG. Mild cognitive impairment in type 2 diabetes mellitus and related risk factors: a review. Rev Neurosci 2017:28(7):715-723 https://doi.org/10.1515/revneuro-2017-0016
  4. Kim YS. Diabetes and cognitive function in community-dwelling older adults. J Krean Acac Community Health Nurs 2011;22(4):377-3888 (Korean) https://doi.org/10.12799/jkachn.2011.22.4.377
  5. Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holmanet RR. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000;321(7258):405-412 https://doi.org/10.1136/bmj.321.7258.405
  6. He X, Li J, Wang B, Yao Q, Li L, Song R, Shi X, Zhang J. Diabetes self-management education reduces risk of all-cause mortality in type 2 diabetes patients: a systematic review and meta-analysis. Endocrine 2017;55(3):712-731 https://doi.org/10.1007/s12020-016-1168-2
  7. Lee SH. Effect of self-efficacy promoting program on self-efficacy, metabolic control and self-care behaviors in patients with NIDDM. Korean J Rehabil Nurs 2005;8(1):59-67 (Korean)
  8. Kwon YE, Kim YS. Factors related to self-management the elderly people with diabetes mellitus in a community dwelling. J Korean Soc Living Environ Sys 2011;18(1):92-100 (Korean)
  9. Sinclair AJ, Girling AJ, Bayer AJ. Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services. All Wales Research into Elderly (AWARE) Study. Diaabetes Res Clin Pract 2000;50(3):203-212 https://doi.org/10.1016/S0168-8227(00)00195-9
  10. Novak V, Gomez F, Dias AC, Pimentel DA, Alfaro FJ. Diabetes-related cognitive decline, a global health issue and new treatment approaches. Int J Priv Health Inf manag 2017;5(2):58-70 https://doi.org/10.4018/IJPHIM.2017070104
  11. Youn JC. Association between subjective memory complaint and objective cognitive decline in the elderly. Kor J Psychopathol 2003;12(1,2):17-23 (Korean)
  12. Montejo P, Montenegro M, Fernandez MA, Maestu F. Memory complaints in the elderly: Quality of life and daily living activities. A population based study. Arch Gerontol Geriatr 2012;54(2);298-304 https://doi.org/10.1016/j.archger.2011.05.021
  13. Lee SA, Lee WH, Song JY, Paik JW. Association between subjective memory complaints and objective cognitive functions in the elderly. Kor J Clin Psychol 2011;30(1):247-261 (Korean) https://doi.org/10.15842/kjcp.2011.30.1.013
  14. Treves TA, Verchovsky R, Klimovitzky S, Korczyn AD. Incidence of dementia in patients with subjective memory complaints. Int Psychogeriatr 2005;17(2);265-273 https://doi.org/10.1017/S1041610205001596
  15. Cukierman T, Gerstein HC, Williamson JD. Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies. Diabetologia 2005;48(12);2460-2469 https://doi.org/10.1007/s00125-005-0023-4
  16. Allen KV, Frier BM, Strachan MW. The relationship between type 2 diabetes and cognitive dysfunction: longitudinal studies and their methodological limitations. Eur J Pharmacol 2004;490(1-3):169-175 https://doi.org/10.1016/j.ejphar.2004.02.054
  17. Lee SH. Connections between diabetes and cognitive dysfunction. J Korean Diabetes 2019;20(1):67-73 (Korean) https://doi.org/10.4093/jkd.2019.20.2.67
  18. Jung M, So H. Cognitive function in non-insulin dependent diabetic patients. korean J Rehabil Nurs 2005;8(1):38-49 (Korean)
  19. Ebady SA, Arami MA, Shafigh MH. Investigation on the relationship between diabetes mellitus type 2 and cognitive impairment. Diabetes Res Clinic Pract 2008;82(3):305-309 https://doi.org/10.1016/j.diabres.2008.08.020
  20. Guerrero-Berroa E, Ravona-Springer R, Schmeidler J, Heymann A, Soleimani L, Sano M, Leroith D, Preiss R, Zukran R, Silverman JM, Beeri MS. Depressive symptoms are associated with cognitive function in the elderly with type 2 diabetes. J Alzheimers Dis 2018;65(2):683-692 https://doi.org/10.3233/JAD-170778
  21. Xia SS, Xia WL, Huang JJ, Zou HJ, Tao J, Yang Y. The factors contributing to cognitive dysfunction in typw 2 diabetic patients. Ann Transl Med 2020;8(4):104. http://dx.doi.org/10.21037/atm.2019.12.113
  22. KDCA. 2018 Survey Questionnaire Guide for Community Health Survey. Cheongju: Korea Disease Control and Prevention Agency [cited 2022 September 19]. Available at https://chs.kdca.go.kr/chs/igm/igmMain.do (Korean)
  23. Lee S, Huh Y, Kim J, Han C. Finding optimal cut off points of the Korean Version of the Patient Health Questionnaire-9 (PHQ-9) for screening depressive disorders. J of Kor Soc for Dep and Bip disorders 2014;12(1):32-36 (Korean)
  24. KDCA. 2008-2018 Community Health Statististics at a glancee, 2019. Cheongju: Korea Disease Control and Prevention Agency [cited 2022 September 19]. Available at https://chs.kdca.go.kr/chs/stats/statsMain.do (Korean)
  25. Hagger-Johnson G, Sabia S, Brunner EJ, Shipley M, Bobak M, Marmot M, Kivimaki M, Singh-Manoux A. Combined impact of smoking and heavy alcohol use on cognitive decline in early old age: Whitehall II prospective cohort study. Rj J Psychiatry 2013;203(2):120-125 https://doi.org/10.1192/bjp.bp.112.122960
  26. Shin HY, Chung EK, Rhee JA, Yoon JS, Kim JM. Prevalence and related factors of dementia in an urban elderly population using a new screening method. J Prev MEd Public Health 2002;38(3):351-358 (Korean)
  27. Anstey KJ, von Sanden C, Salim A, O'Kearney R. ASmoking as a risk facfor for dementia and cognitive decline: a meta-analysis of prospective studies.. Am J Epidemiol 2007;166(4):367-378 https://doi.org/10.1093/aje/kwm116
  28. Blomster JI, Woodward M, Zoungas S, Hillis GS, Harrap S, Neal B, Poulter N, Maancia G, Chalmers J, Huxley R. The harms of smoking and benefits of smoking cessation in women compared with men with type 2 diabetes: an observational analysis of the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron modified relaease Controlled Evaluation) trial. BMJ Open 2016;6:e0009668. doi:10.1136/bmjopen-2015-009668
  29. Okereke OI, Kang JH, Cook NR, Gaziano JM, Manson JE, Buring JE, Grodstein F. Type 2 diabetes mellitus and cognitive decline in two large cohorts of community dwelling older adults. J Am Geriatr Soc 2008;56(6):1028-1036 https://doi.org/10.1111/j.1532-5415.2008.01686.x
  30. Rehm J, Gmel Sr GE, Gmel G, Hasan OSM, Imtiaz S, Popova S, Probst C, Roerecke M, Room R, Samokhvalov AV, Shield KD, Shuper PA. The relationship between different dimensions of alcohol use and the burden of disease-an update. Addiction 2017;112(6):968-1001 https://doi.org/10.1111/add.13757
  31. Loe H. Peridontal disease. The sixth complication of diabetes mellitus. Diabetes care. 1993;16(1):329-334
  32. Teixeira FB, Saito MT, Matheus FC, Prediger RD, Yamada ES, Maia CSF, Lima RR. Periodontitis and Alzheimer's disease: A possible comorbidity between oral chronic inflammatory condition and neuroinflammation. Front Aging Neurosci 2017;9:327. http://dx.doi.org/10.3389/fnagi.2017.00327