• Journal of Veterinary Clinics
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• v.22 no.3
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• pp.264-267
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• 2005

A 12-year-old, 8.0 kg, spayed female, mixed-breed dog was presented to the Veterinary Medical Teaching Hospital of Chungnam National University (VMTH, CNU). That case has been growing up mass in her left upper hindlimb about for 2 years and has showed vomiting and anorexia for 3 days. The patient was diagnosed with mast cell tumor on the basis of fine-needle aspiration (FNA) cytology techniques. According to World Health Organization clinical staging system for diagnosing mast cell tumors, it was classified into stage IIIa. The patient was treated by adjuvant corticosteroid therapy, but complete surgical excision was not achieved by owner's request. In the early stage of therapy, the size of the mass was gradually reduced with only adjuvant glucocorticoid therapy, so the patient's general condition was maintained well. But after 53 days later, the treatmant was not effective anymore and mass size was increased. Two months later, she was euthanized because of intermittent vomiting and severe respiratory distress. Splenic mass, duodenal ulceration, liver mass and infiltrated mast cell tumor in upper hindlimb muscle region were found in necropsy examination.

• Journal of Life Science
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• v.23 no.10
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• pp.1288-1294
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• 2013

Knowledge of morphological changes in eel larvae is very important for artificial rearing of eel larvae. In this study, we investigated the morphological structure of the head region and histological changes of the eye retina in artificially reared larvae at various stages and in glass eel just after metamorphosis. Structural changes were observed in the upper jaw (maxilla) and the lower jaw (mandible) after 100 dah (day after hatchery) and after metamorphosis. Teeth had degenerated by the time of completion of metamorphosis. Major histological changes observed in the eye retina were the formation of the outer plexiform layer and the outer nuclear layer from 100 dah larva and a change in the rod cell layer after metamorphosis. The cornea was not observed at 10 dah in the eel larva. More information is needed on the early developmental stages of eel larvae to enable mass production of glass eels. The results obtained in the present research will be useful when developing novel rearing programs for eel larvae.

• Journal of Life Science
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• v.23 no.3
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• pp.347-354
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• 2013

Innate immunity is the ability to differentiate infectious agents from self. The innate immune system is comprised of a complicated network of recognition and effector molecules that act together to protect the host in the early stage of an infectious challenge. Mannose-binding lectin (MBL or mannose-binding protein, MBP) belongs to the family of $Ca^{2+}$-dependent lectins (C-type lectin with a collagen-like domain), which are considered an important component of innate immunity. While it is associated with increased risk and severity of infections and autoimmunity, the most frequent immuno-deficiency syndrome was reported to be low MBL level in blood. Deficiency of human MBL is caused by mutations in the coding region of the MBL gene. Rat homologue gene of human MBL gene was used to study functions of wild type and mutant MBL proteins. Although extensive studies have yielded the structural information of MBL, the functions of MBL, especially mutant MBL, still require investigation. We previously reported the cloning of rat wild-type MBL gene and the production of a truncated form of MBL protein and its antibody. Here, we present the cloning of mutant MBL cDNA in collagen-like domain (R40C, G42D, and G45E) using site-directed mutagenesis and differential behaviors of wild type and mutant MBL in cells. The major difference between wild type and mutant MBL was that while wild type MBL was secreted, mutant MBL was inhibited for secretion, retained in endoplasmic reticulum, and still functioned as a lectin.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.444-454
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• 2015

This study reports on initial founder performance and satisfaction that is affected by mentoring skills and mentoring functions. Through the empirical analysis, seen the initial founder performance and satisfaction as a respective dependent variable, this study intends to provide efficient direction of the responsibility mentor and present a method that enhances the survival of the initial start-up founder. The frequency analysis was conducted to determine the general characteristics of the sample, by leveraging the statistical package SPSS 20.0 for Windows program, details of the items measuring tools present a statistical analysis of sample data, 120 people have gathered in the survey data for this factor analysis was performed with a correlation to classify each region was calculated to Cronbach's ${\alpha}$ factor to determine the reliability of the measurement tool, and tested the hypothesis using linear regression analysis for verification. Was found to play an important role to draw the founder and mentor mentoring skills and capabilities in early stage start-ups, and conclusions drawn from this process. In particular, modeling of the mentor with a sound mind and behavior brought the better performance and satisfaction of the initial start-up founder. If a mentor provides mentoring with more interests in career development and psychosocial functions of the mentoring functions, it is seen to be more efficient way to improve survival rate of initial start-up as well as increasing a founder's performance and satisfaction.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.3
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• pp.388-393
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• 2000

Cleft lip and palate is one of the most common congenital defects in oro-maxillo-facial region. Because most patients undergo surgical repair in early life, the sagittal jaw relationships used to be deteriorated gradually from palate surgery up to adulthood. Also, the maxillary lateral incisor may be absent or atypical-shaped in the cleft site and may not erupt or erupt ectopically, so multidisciplinary dental cares are needed for cleft lip and palate patients. The effects of the cleft lip and alveolus seem to be limited to that part of the dentofacial complex that surrounds the cleft area. In the maxillary arch, the anterior part of the non cleft segment has a tendency to be rotated forward. On the other hand, the cleft segment has a tendency to rotated slightly medially ; hence, the tendency for canines to be edge-to-edge and sometimes in crossbite. Lip and alveolus surgery adequetely correct these problems, with little untoward effect on the skeletal maxillary-mandible relationships. In this report, the patient has a repaired lip and cleft alveolus on the left side with congenital missing on '62, '22, oronasal fistula, and skeletal class III malocclusion which is not affected by lip surgery. Dental treatments for this patient including orthodontic(space supervision, functional regulator in mixed dentition, fixed therapy in permanent dentition) and prosthodontic(removable obturator with key and keyway attachment and Konus crown) therapy were performed to improve the patient's functions and esthetics.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.37.3-38
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• 2016

Recent studies suggest that faint active galactic nuclei may be responsible for the reionization of the universe. Confirmation of this scenario requires spectroscopic identification of faint quasars ($M_{1450}$ > -24 mag) at z > 6, but only a very small number of such quasars have been spectroscopically identified so far. Here, we report the discovery of a faint quasar IMS J220417.92+011144.8 at z ~ 6 in a $12.5deg^2$ region of the SA22 field of the Infrared Medium-deep Survey (IMS). The spectrum of the quasar shows a sharp break at ${\sim}8443{\AA}$, with emission lines redshifted to $z=5.944{\pm}0.002$ and rest-frame ultraviolet continuum magnitude $M_{1450}=-23.59{\pm}0.10$ AB mag. The discovery of IMS J220417.92+011144.8 is consistent with the expected number of quasars at z ~6 estimated from quasar luminosity functions based on previous observations of spectroscopically identified low-luminosity quasars. This suggest that the number of $M_{1450}$ ~ -23 mag quasars at z ~ 6 may not be high enough to fully account for the reionization of the universe. In addition, our study demonstrates that faint quasars in the early universe can be identified effectively with a moderately wide and deep near-infrared survey such as the IMS.

• Korean journal of applied entomology
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• v.56 no.4
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• pp.421-426
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• 2017

These experiments were conducted to investigate the morphological characteristics, occurrence ecology, host preference, and oviposition of Locusta migratoria to create a forecasting manual in preparation for outbreaks of this species. The sex ratio (female:male) of 274 adult of L. migratoria which occurred naturally in the Muan region of Jeollanam-do was 18.2 : 81.8, 60.9% individuals were of the green type and 39.1% were of the brown type. Body length and body weight were 6.5 cm and 2.8 g for females and 5.0 cm and 1.5 g for males, respectively; body size did not differ between differently colored individuals. Spawning activity in the field was observed from late August to late October. Eggs laid between late September and early October hatched in late May the following year. Female adults fed 3.5 g of corn leaf and male adult was 1.6 g for a day. The host preference of L. migratoria was in the order corn > foxtail millet > millet > silver grass > rice, and preference for silver grass and rice was very low. Pure sand was most favorable for the spawning of L. migratoria, and the cumulative amount of hatching was higher when the soil moisture content was higher after spawning began.

• Journal of Convergence for Information Technology
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• v.7 no.5
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• pp.1-13
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• 2017

It is revealed that there are more registered disabled people in our country who have their disability because of acquired factors such as accidents than because of innate deformity. This phenomenon will continue and the incidence of acquired disability will increase more and more. Even though there is noticeable change, the social recognition toward the disabled is still negative. Particularly, university students are in the early adulthood according to the development of life-cycle, and this is the period that people have diverse social relationships, depart from unified frame and work in various fields, and set up their own thoughts and ideology with knowledge and skills acquired from university education. Therefore, in this study, we are going to search the recognition of the university students, who are in the previous period of entering into the society, toward the disabled, and if they have negative prejudice or attitude against the disabled, we are going to find the ways to improve on their awareness positively. The subjects of the survey were randomly selected among 230 out of total 250 students by visiting thirteen universities in Chungcheong Province, and were analyzed by using SPSS (ver. 18.0) program. T-test and One-way ANOVA were used as analytical methods to look into the difference of analysis of frequency, descriptive statistic, reliability analysis and attitudes for comprehending sociodemographic characteristics of the subjects of the survey. In conclusion, it has to be not a temporary or event-like training, but a training that makes people have positive recognition and attitude towards accurate information, knowledge, human rights, disability, and diversity. This thesis has a limitation to be generalized to the university students all over the country since the region is limited to a certain area.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.2
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• pp.183-189
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• 2018

Blue light is the highest energy wavelengths in the visible light region and induces skin aging and active oxygen. Studies on harmful mechanism of skin are under way. Research on blue light blocking materials in cosmetics and formulation studies are in the early stage, and the test methods related to blue light blocking measurement are not established. The blue light blocking efficacy was established by referring to the test method of the sunscreen in vitro test(COLIPA guideline, ISO 24443, FDA Final Rule on Sunscreen Testing and Labeling). The blue light blocking effect was evaluated for 17 kinds out of 27 kinds of sunscreen raw materials suggested in KFDA guideline. The Effect was 14.97% for zinc oxide and 16.32% for bishexyloxyphenol methoxyphenyl triazine, 35.47% for methylene bis-benzotriazolyltetramethylbutylphenol, and 65.96% for titanium dioxide. In addition, the effect of micro-titanium dioxide was twice as high as that of the nano-titanium dioxide. The results suggested that the light blocking effect test method can be used to search for blue light blocking materials and study cosmetic formulations.

• Korean journal of applied entomology
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• v.13 no.4 s.21
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• pp.209-216
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• 1974

Life history and control methods of Aphanostigma iakusuiense Kishida were studied during April to November, 1974, in the Naju pear orchard area, Cholla Namdo. The results are summarized as follows: 1. More than $60\%$ of wintering eggs were found at the height of 1.5 to 2.0m from the soil surface, with approximately $10\%$ at 0.5 to 1.5m and 1.5 to 2.5m respectively. 2. There was little difference in the size of egg masses and hatching ratio $(12.7-13.7\%)$ between the varieties of host trees, Mansamkil and Kooksoo. 3. Hatching was not observed until April 6, but hatches of $12.8\%$ on April 13 and $90.6\%$ on May 4 were found. 4. During the hatching season in early spring, 8 chemicals were applied to test effectiveness of control. C8514, Metasystox, Acar 338, and Parathion were more effective than either Sevin or Malix for control of this insect. 5. Highest populations of pear phylloxera ocurred from August 20 to September 20 at which time levels of eggs and larvae were simillar in abundance. 6. In tests for control of this insect after in paper bags, DDVP, Loxon, C8514, Sevin, and Binapacryl were more effective than either EPN or Otran. 7. Predacious mite, Protolaelape pygmaeus Miller, and several species of lady beetles (Coccinellidae) preying on this insect as natural enemies were collected. The predation ratio of mites varied according to region: that is 0.77 to $18.6\%$ in Bia Orchard; $7.88-48.7\%$ in Noan Orchard and almost none in Youngsanoo Orchard. 8. The varietal difference in fruit damage by this insect was in the order of Choseng Chuck, Kooksoo, followed by Sin Ko, Mansamkil, Keumchon Choo, and Changsimrang.