• 대한가정학회지
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• 제19권2호
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• pp.1-9
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• 1981

The phenomena of memory have been shown to come out early in life and to develop drastically for early childhood. Therefore, the purpose of this study were examine the development of memory of Korean children and also to see the memory span of Korean children. the subjects in this study were 80 children (male and female each 40 children) from age 3 to age 6. These subjects were devide into two age groups (3~4 age, 5~6 age). the stimulus materials were the numbers and the words. The numbers in this study were chosen from the number problems of WISC. The 42 words which consisted of two phonemes were selected. The number of items was 3 to 9 on the first through the last trial. altogether 14 trials, 7 trials for numbers and 7 trials for words, were given to each subject. Free recall method was sued. The following conclusions could be made. 1. The memory span of Korean early childhood increased as the age of the children increased. 2. The primacy effect was appeared when the age increased. Therefore, rehearsal was appeared as the age of the Korean early childhood increased.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2001년도 봄 학술발표회 논문집
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• pp.10-17
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• 2001

With the introduction of durability examination into design code of concrete structure, a prediction of early-age behavior of concrete and its cracking resistance becomes very important. But, the early-age behaviors such as hydration, micro-structure development, moisture transport and mechanical properties development is quite complicated and coupled each other, and thus those can not be solved independently. One way to analyze those is to model their behaviors analytically and solve those computationally within a unified framework. In this paper, we propose a finite element technique to predict the early-age behaviors of concrete within the unified framework. The technique is applied to evaluatio of cracking in a massive concrete structure and then the analysis results are discussed.

• 아동학회지
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• 제26권5호
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• pp.205-216
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• 2005

This study investigated aspects of caregiver's input relating to the early development of nouns and verbs. Subjects were 34 Korean-Chinese children in Yanji, China. At 1 year of age each child's spontaneous speech during interaction with his/her caregiver was videotaped for about 30 minutes. The children's spontaneous utterances were transcribed and coded on the lexical level(nouns and verbs) and the pragmatic level. Children's speech was recorded, transcribed and coded again at 2 years of age. Results showed that children used more verbs when they were older; there were no differences between the two ages in mother's pragmatic utterances but when they were two-years-old children used more actionoriented utterances and object-described utterances. Mother's input was related to children's pragmatic utterances.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 추계 학술발표회 제16권2호
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• pp.731-734
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• 2004

Admixture compounds for reducing setting time and accelerating early strength development of redispersible polymer powder-modified mortars were made by mixing various inorganic accelerating inorganic materials. Redispersible polymer powder-modified mortars are prepared with various accelerator contents, and it was tested for setting time, flexural and compressive strengths. As a result, the accelerators contribute to strength development of the mortars in the early curing age of 12h or less. In the viewpoint of early strength development of redispersible polymer powder-modified mortars, an accelerator content of $20\%$ is recommended.

• Clinical and Experimental Pediatrics
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• 제58권3호
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• pp.77-83
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• 2015

Relative to a fetus of the same gestational age, very low birth weight (VLBW) infants are more likely to be underfed and to undergo growth restriction during their early hospital stay. The current trend towards "early and aggressive" nutritional strategies in VLBW infants aims to overcome the early nutritional deficiency and thereby boost postnatal catch-up growth, simultaneously improving long-term neurodevelopmental outcomes. Although the minimum starting amino acid (AA) dose to prevent negative nitrogen balance is well established, the upper limit and the rate of increase of early AA doses are controversial. Most randomized controlled trials show that early and high-dose (target, 3.5 to 4.9 g/kg/day) AA regimens, with or without high nonprotein calories, do not improve long-term growth and neurodevelopment. High-dose AA supplementation may lead to early metabolic disturbances and excessive or disproportionate plasma AA levels, particularly in infants of very low gestational age. Further large studies are needed to clarify the optimal strategy for early administration of parenteral AA doses in VLBW infants.

• 한국발생생물학회지:발생과생식
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• 제18권3호
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• pp.153-160
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• 2014

Adaptive development of early stage embryo is well established and recently it is explored that the mammalian embryos also have adaptive ability to the stressful environment. However, the mechanisms are largely unknown. In this study, to evaluate the possible role of aquaporin in early embryo developmental adaptation, the expression of aquaporin (AQP) 5 gene which is detected during early development were examined by the environmental condition. To compare expression patterns between in vivo and in vitro, we conducted quantitative RT-PCR and analyzed localization of the AQP5 by whole mount immunofluorescence. At in vivo condition, Aqp5 expressed in oocyte and in all the stages of preimplantation embryo. It showed peak at 2-cell stage and decreased continuously until morula stage. At in vitro condition, Aqp5 expression pattern was similar with in vivo embryos. It expressed both at embryonic genome activation phase and second mid-preimplantation gene activation phase, but the fold changes were modified between in vivo embryos and in vitro embryos. During in vivo development, AQP5 was mainly localized in apical membrane of blastomeres of 4-cell and 8-cell stage embryos, and then it was localized in cytoplasm. However, the main localization area of AQP5 was dramatically shifted after 8-cell stage from cytoplasm to nucleus by in vitro development. Those results explore the modification of Aqp5 expression levels and location of its final products by in vitro culture. It suggests that expression of Aqp5 and the roles of AQP5 in homeostasis can be modulated by in vitro culture, and that early stage embryos can develop successfully by themselves adapting to their condition through modulation of the specific gene expression and localization.

• 한국발생생물학회지:발생과생식
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• 제18권4호
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• pp.233-240
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• 2014

The early growth response protein 1 (Egr-1) is a widely reported zinc finger protein and a well known transcription factor encoded by the Egr-1 gene, which plays key roles in many aspects of vertebrate embryogenesis and in adult vertebrates. The Egr-1 expression is important in the formation of the gill vascular system in flounders, which develops during the post-hatching phase and is essential for survival during the juvenile period. However, the complete details of Egr-1 expression during embryo development in olive flounder are not available. We assessed the expression patterns of Egr-1 during the early development of olive flounders by using reverse transcription polymerase chain reaction (RT-PCR) analysis. Microscopic observations showed that gill filament formation corresponded with the Egr-1 expression. Thus, we showed that Egr-1 plays a vital role in angiogenesis in the gill filaments during embryogenesis. Further, Egr-1 expression was found to be strong at 5 days after hatching (DAH), in the development of the gill vascular system, and this strong expression level was maintained throughout all the development stages. Our findings have important implications with respect to the biological role of Egr-1 and evolution of the first respiratory blood vessels in the gills of olive flounder. Further studies are required to elucidate the Egr-1-mediated stress response and to decipher the functional role of Egr-1 in developmental stages.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권1호
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• pp.1-11
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• 2018

The emergence of mucosal healing as a treatment goal that could modify the natural course of Crohn's disease and the accumulating evidence showing that biologics are most effective in achieving mucosal healing, along with the success of early treatment regimens for rheumatoid arthritis, have led to the identification of early Crohn's disease and development of the concept of catching the therapeutic window during the early disease course. Thus, an increasing number of pediatric gastroenterologists are adopting an early biologic treatment strategy with or without an immunomodulator. Although early biologic treatment is effective, cost and overtreatment are issues that limit its early use. Currently, there are insufficient data on who will benefit most from early biologics, as well as on who will not need early or even any biologics. For now, top-down biologics should be considered for patients with currently known high-risk factors of poor outcomes. For other patients, close, objective monitoring and accelerating the step-up process by means of a treat-to-target approach seems the best way to catch the therapeutic window in early pediatric Crohn's disease. The individual benefits of immunomodulator addition during early biologic treatment should be weighed against its risks and decision on early combination treatment should be made after comprehensive discussion with each patient and guardian.

• 아동학회지
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• 제30권3호
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• pp.161-175
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• 2009

The purpose of this study is to develop proper early childhood information communication ethics education program and apply it to children based on previous researches and demands of early childhood teacher in order to protect children who remain defenseless in the information society. The draft was developed after analyzing previous research and survey of early childhood teachers' perception and demands on early childhood information communication ethics education. On the basis of the draft and the survey, the early childhood information communication ethics education program was developed after examining the adequacy of each item and subordinate areas which was conducted by early childhood professionals and applied 17 children. Moreover, early childhood information communication ethics attitude surveys were carried out before and after the program to obtain effects of the early childhood information communication ethics education program. The early childhood information communication ethics education program was effective. There was significant difference (t=-2.27, p<.05) of mean score between experiment group and control group.

• 한국산학기술학회논문지
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• 제19권8호
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• pp.441-448
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• 2018

이 연구는 글 없는 그림책 활동이 유아의 그림 표상능력과 사회성 발달에 미치는 영향을 알아보는데 그 목적이 있다. 이를 위해 연구대상은 K유치원에 재학 중인 만 3세 유아 30명으로 하였다. 그 중 15명을 실험집단으로 나머지 15명을 비교집단으로 선정하였다. 실험처치는 실험집단에 8주간 글 없는 그림책 활동을 실시하였으며, 두 집단 모두 그림 표상능력과 사회성 발달 검사를 사전 사후에 실시하였다. 그 결과, 글 없는 그림책 활동이 유아의 그림 표상능력 하위 영역 중 다양한 색채, 세부적 묘사, 조화로운 공간 표상, 다양한 형체, 주제 관련 표상, 표상의 독특성, 그림 표상의 완성도, 언어 표상의 연결에 효과가 있는 것으로 나타났다. 다음으로 글 없는 그림책 활동이 유아의 사회성 발달 하위영역 중 협동성, 자율성, 또래 간 상호작용에서 효과가 있는 것으로 나타났다. 이러한 연구결과는 글 없는 그림책 활동이 유아의 그림 표상능력과 사회성 발달에 효과적인 교수-학습 자료로 유아교육기관에서 유용하게 활용될 수 있음을 시사한다.