• Journal of Korean Medical Ki-Gong Academy
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• v.11 no.1
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• pp.221-235
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• 2009

This study is made for the survey of the effectiveness of the auricular reflexology, now accepted as a part of alternative medicine, applied to the patients of musculoskeltal disease patients, and data about its cognition and the success rate of the therapy. 106 patient was employed in this study who works in various part in a company in Jun-ju in Junrabukdo. From them, data such as, musculoskeletal symptoms by questionnaire examination, and data from ear inspections and interviews were collected and used for the basal data. Auricular reflexology therapies were applied to them at the areas that reflect the musculoskeletal system, for five times, each time with intervals of three or four days. The data about the effectiveness were collected by questionnaire examination, including descriptive answers. The results are as follows; cognition to the auricular reflexology was 62.3%, and acceptance rate of this method was 81.1%. From this results, I think that this therapy can be easily acceptable. The success rates of this therapy were 32.1% after 1 time application, and 84.9% after 5 times applications. This result shows that auricular reflexology therapy has therapeutic effect in musculoskeletal diseases, and the success rates increase according to the application times. Between sex, its success rate were 80% in male patients, and 88.5% in female patients, so this therapy is rather more effective in female patients. According to the body weight, the success rate were 85.8% in normal weight patients, and 71.5% in over- weight patients, so this therapy is more effective in normal weight patients. Comparisons according to other factors, such as age, marriage state etc. shows no definite differences. Conclusively, I think that auricular reflex therapy is easy and useful preventative and treatment method in our usual life. With more investigation, we can apply this method to other musculoskeletal diseases and to the diseases of other systems in the body, I hope so.

• Preventive Nutrition and Food Science
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• v.17 no.1
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• pp.14-21
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• 2012

The purpose of this study was to investigate the anti-allergy activities of persimmon leaf extract (PLE) on a phthalic anhydride (PA)-induced allergic mouse model. A human leukemic mast cell line (HMC-1) was used to examine the inhibitory activity of PLE on the histamine release by human leukemic mast cells. PLE inhibited histamine release from HMC-1 cells in response to cross-linkage of high-affinity IgE receptor-${\alpha}$ ($Fc{\varepsilon}RI{\alpha}$). Additionally, a PA-induced allergic mouse model was used to investigate the effects of PLE in vivo. Mice were orally administrated with or without PLE of single dose (250 mg/kg/day) for 31 days. Oral intake of PLE significantly inhibited passive cutaneous reactions. Oral administration of PLE to PA-induced allergic mice also led to a striking suppression of the development of contact dermatitis, ear swelling and lymph node weight. In addition, PA-specific IL-4 production of draining lymph node cells was markedly diminished by PLE oral administration, but not IFN-${\gamma}$. Furthermore, PLE treatment suppressed PA-induced thymus and activation-regulated chemokine (CCL17) and cutaneous T cell-attracting chemokine (CCL27) expressions in ear tissues. Based on these results, we suggest that PLE may have therapeutic potential as an effective material for management of irritant contact dermatitis or related inflammatory diseases.

• Herbal Formula Science
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• v.12 no.2
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• pp.57-76
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• 2004

This report describes the remedial fields, symptoms, pathology, dosage, prescriptional constitution of 69 studies related to the use of Radix Asari main blended prescriptions from Dongeubogam. The following conclusions were reached through investigations on the prescriptions that use Radix Asari as a key ingredient. Radix Asari blended prescriptions are utilized for 14 therapeutic purposes, for example, in symptoms of tooth, eye, paralysis, ear-nose, skin infection and carbuncle. In particular, 14.49% of the prescriptions appear in the chapter of tooth, and 10.14% of those appear in the chapter of eye. Prescriptions that utilize Radix Asari as the main ingredient are used in the treatment of dental disease, othalmology, nose and ear disease, throat disease, common cold, dermothology, paralysis, musculoskeletal disease, disease of the head, asthma, genital disease, the injury of the cuts and they are also used for treating 50 different types of diseases. Radix Asari is used in Six pathogenic factors such as wind, wind-cold, wind-heat, wind-dampness heat, wind-dampness, dampness, paralysis, cold-chill, cold, dryness, in visceral pathogenic factors such as stomach, kidney, liver-kidney, liver and in chi-blood pathogenic factors such as chi-blood deficiency, chi-blood stagnation and in extravasated blood pathogenic factors such as impact injury, an injury such as cuts, blood accumulation as well as weakness-cold and parasites. The actual amount of Radix Asari blended has ranged at a wide variety of amounts from 2.5pun(about 0.94gram) to 3don(about 11.25gram). 26.09% of the prescriptions used 1don(about 3.75gram). The function of Radix Asari is to calm down, to get the consciousness back, to bore through, to warm up the meridians and to run it smoothly, to discharge of phlegm from the combination of drugs and prescriptions.

• The Journal of Pediatrics of Korean Medicine
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• v.12 no.1
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• pp.183-210
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• 1998

Cheonggisan(CGS) is well known for its effect on such allergic disease as urticaria and atopic dermatitis. Gagamcheonggisan(GCGS) was formulated by subtracting several herbs from CGS and adding several herbs to CGS. Even though it is being used frequently in the clinicai medicine for the treatment of above hypersensitivity diseases, basic study to make sure the mechanism of its action is rare. In this study the author tried to know the effect of CGS and GCGS on the vascular permeability, contact dermatitis, granular secretion from mast cells and function of macrophages. The results obtained in this study are as follows : 1. Administration of CGS and GCGS decreased the vascular permeability induced by serotonin and histamine. The decrease by serotonin is more typical and dose-dependent. 2. Administration of CGS and GCGS inhibited foot-pad and ear swelling responses induced by sheep red blood cells and picryl chloride respectively, the inhibition of foot-pad swelling responses is bigger than that of ear swelling responses and both of them are not dependent on the dose3. Treatment of peritoneal mast cells with CGS and GCGS water extract decreased the histamine release triggered by compound 48／80 in a dose dependent fashion 4. Administration of CGS and GCGS increased the phagocvtic activity of peritoneal macrophages and treatment of peritoneal macrophages with CGS activated phagocytic function in a dose dependent fashion. 5. Administration of CGS and GCGS enhanced such reactive oxygen intermediates(ROIs) as superoxide and hydrogen peroxide production from peritoneal macrophages. 6. Treatment of CGS and GCGS activated peritoneal macrophages for the production of ROIs. The above results show that CGS and GCGS decreased the hypersensitivity reactions by inhibiting non-specific inflammatory mediator release and vascular permeability without affecting general immune responsiveness.

• Journal of Acupuncture Research
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• v.33 no.1
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• pp.69-77
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• 2016

Objectives : The objective of this study is to review external approaches using acupuncture and related treatments of hyperpigmentation disorders and their classification in traditional medicine. Methods and Results : Hyperpigmentation was recorded for the first time in Treatise on the Pathogenesis and Manifestations of All Diseases published in 610 A.D. This suggests that the symptom has already been recognized as an independent disease in East Asia for more than 1,400 years. Over the course of several centuries, there has been a significant evolution in the traditional treatments for hyperpigmentation. There are many different types of therapy, including body acupuncture, intradermal acupuncture, ear acupuncture, ear acupressure, blood-letting treatment, pharmacopuncture, plum-blossom needle therapy, burning acupuncture therapy, moxibustion, and guasha. In addition, the traditional classification of hyperpigmentation has been changing shape. However, no attempts have been made to establish the academic linkage between the modern classification of hyperpigmentation disorders and the traditional one, on account of different concepts and names of the ailment. This study was designed in an attempt to identify the linkage of the categorization of the Korean Standard Classification of Disease (KCD) and the traditional classification. Conclusions : Through this literature review, we found that there has been a significant evolution in the treatment of hyperpigmentation disorders in East Asia. Traditional medical treatment for skin disease, including hyperpigmentation, is expected to be further developed with the advancement of science and technology.

• Journal of Veterinary Clinics
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• v.15 no.2
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• pp.450-454
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• 1998

These studies were performed to find out the possibility of automatic detection of the diseased animal with fever by farmers themselves. Firstly, the body temperature of 331 dairy cows was investigated according to major disease symptoms manifested. Secondly, AD 590 thermometer was used to take the teat temperature of the milking cows to determine the possibility of automatic taking of body temperature while milking. The temperatures of scapha of ear and coccygeal artery part were also taken fur the non-milking dairy cows and Korean native cowl 1. The average body temperature of dairy cows associated with respiratory diseases puerperal disease, or mastitis was higher than normal temperature denoting respectively 39.8,39.6, and $39.3{\circ}C.2.$ The teat temperaure of the milking dairy cows with fever($39.5~39.6{\circ}C$) and the cows with mastitis was respectively 1.02 and 0.56${\circ}C$ higher than that of normal cows. 3. The average teat temperature taken by AD 590 was 33.91, 34.93, and 34.50${\circ}C$ in normal milking dairy cows, cows with fever(39.5~39.6${\circ}C$), and cows with mastitis, respectively. 4. The mean temperatures at scapha and coccygeal part of non-milking dairy cows and Korean native cows were 35.62 and 36.63${\circ}C$, respectively. It was concluded that AD 590 thermometer would be usable for the farmers to automatirally detect the body temperature of dairy cows while milking and subsquently to find the diseased cow with fever and that the scapha of ear and coccygeal artery part of the cattle could be the body parts of simply detecting body temperature of non-milking cattle.

• Advances in Traditional Medicine
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• v.5 no.3
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• pp.188-194
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• 2005

The Angelicae dahuricae radix (ADR) has been used a traditional medicine to treat acne, erythema, headache, toothache, sinusitis, colds, and flu in Korea, Japan and China. Here, we report the effect of ADR on compound 48/80-induced ear-swelling and the phorbol myristate acetate (PMA) plus calcium ionophore A23187-induced inflammatory cytokine secretion in the human mast cell line, HMC-1. ADR dose-dependently inhibited the ear-swelling response induced by intradermal injection of compound 48/80, In vitro model, PMA plus A23187 significantly increased interleukin $(IL)-1{\beta}$, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor $(TNF)-{\alpha}$ secretion compared with media control. We also show that the increased cytokines $IL-1{\beta}$, IL-8, GM-CSF, and $TNF-{\alpha}$ level was significantly inhibited by treatment of ADR. In addition, ADR partially blocked PMA plus A23187-induced extracelluar signal-regulated kinases phosphorylation. These results suggest that ADR might explain its beneficial effect in the treatment of mast cell-mediated inflammatory diseases.

• Korean Journal of Acupuncture
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• v.29 no.1
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• pp.17-22
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• 2012

Objectives : The purpose of this study is to discuss the diagnostic classification of the traditional medicine for pilosis, and the hair removal treatments in traditional medicine and its clinical application. Backgrounds : In recent years, appearance and beauty have become main interest that have positioned in the medical area. In clinical Korean medicine, a variety of methods such as moxibustion, superficial bleeding, multiple microneedling, facial meridian massage, herbal medicine facial pack, laser acupuncture, and intense pulsed light (IPL) have been applied. Methods and Results : Pilosis, a condition of abnormal hair growth, is stated for the first time in the publication, [Pathogenesis and Manifestations of All Diseases] by Chao Yuan-fang in 610 A.D. It shows that pilosis has been recognised as a disease for ages in Asia. Reviewing several publications, we found multiple approaches to pilosis were already existed in korean medicine. They include internal medicinal classification and its' medications. Acupuncture treatments also focused on regulation of radical causes and superficial removal of abnormal hairs. Specific treatments includes body and ear acupuncture, ear acupressure, hypodermic acupuncture, hypodermic acupuncture injection, laser acupuncture treatment. Physical and chemical methods of hair removal were widely invented. we resulted that significant scientific approaches to pilosis are under way in the korean medical field, and found a variety of medical treatments such as herbal medicines and dermatological methods. Conclusions : Hair removal treatments for pilosis in traditional medicine has a long history. Combined with advanced modern technology it can achieve greater advance in cosmetology.

• Biomedical Science Letters
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• v.28 no.3
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• pp.186-191
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• 2022

The use of earphones has recently been widely used around the world. In currently, students wear earphones a lot in a daily life. The types of earphones are open-earphones, Canalphones, and headphones. Many students don't periodically to sterilization their earphones. Therefore, it can be an incubator that can induced ear infections. The objective of this study was to detect the pathogenic bacteria from the earphones used by the students. A total of 3 type earphones swabs were collected by sterile cotton swabs. The swabs were inoculated onto BHI agar and incubated aerobically 48 hour at 37℃. 16s rRNA PCR, electrophoresis and sequencing were performed to confirm the identification of all the bacterial isolates. As a result, 24 pathogens were identified in sequencing. Three types of earphones were sterilized in three ways: ultraviolet (UV), 70% ethyl alcohol, and antibacterial wet tissue. If you use earphones for a long time without disinfecting them for a long time, it causes various diseases such as external ear infections. The findings of this study the users periodically to sterilization their respective earphones.

• Journal of Korean Home Economics Education Association
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• v.20 no.2
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• pp.75-94
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• 2008

The purposes of this paper are to describe the newly established reference values of nutrient intakes: to apply the changed dietary reference intakes to the new text book based on the revised curriculum: and to contrive substantial contents in the domain of dietary life(foods & nutrition) of new text book. Dietary Reference Intakes for Koreans(KDRIs) is newly established reference values of nutrient intakes that are considered necessary to maintain the health of Koreans at the optimal state and to prevent chronic diseases and overnutrition. Unlike previously used Recommended Dietary Allowances for Koreas(KRDA), which presented a single reference value for intake of each nutrient, multiple values are set at levels for nutrients to reduce risk of chronic diseases and toxicity as well as prevention of nutrient deficiency. The new KDRIs include the Estimated Average Requirement(EAR), Recommended Intake(RI), Adequate Intake(AI), and Tolerable Upper Intake Level(UL). The EAR is the daily nutrient intake estimated to meet the requirement of the half of the apparently healthy individuals in a target group and thus is set at the median of the distribution of requirements. The RI is set at two standard deviations above the EAR. The AI is established for nutrients for which existing body of knowledge are inadequate to establish the EAR and RI. The UL is the highest level of daily nutrient intake which is not likely to cause adverse effects for the human health. Age and gender subgroups are established in consideration of physiological characteristics and developmental stages: infancy, toddler, childhood, adolescence, adulthood and old age. Pregnancy and lactation periods were considered separately and gender is divided after early childhood. Reference heights and weights are from the Korean Agency for Technology and Standards, Ministry of Commerce, Industry and Energy. The practical application of DRIs to the new books based on the revision in the 7th curriculum is to assess the dietary and nutrient intake as well as to plan a meal. It can be utilized to set an appropriate nutrient goal for the diet as usually eaten and to develop a plan that the individual will consume using a nutrient based food guidance system in the new books based on the revision in the 7th curriculum.