• Asian-Australasian Journal of Animal Sciences
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• v.33 no.1
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• pp.166-176
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• 2020

Objective: An experiment was conducted to determine the effects of L-arginine (L-Arg) and N-carbamoylglutamic acid (NCG) on the growth, metabolism, immunity and community of cecal bacterial flora of weanling and young rabbits. Methods: Eighteen normal-grade male weanling Japanese White rabbits (JWR) were selected and randomly divided into 6 groups with or without L-Arg and NCG supplementation. The whole feeding process was divided into weanling stage (day 37 to 65) and young stage (day 66 to 85). The effects of L-Arg and NCG on the growth, metabolism, immunity and development of the ileum and jejunum were compared via nutrient metabolism experiments and histological assessment. The different communities of cecal bacterial flora affected by L-Arg and NCG were assessed using high-throughput sequencing technology and bioinformatics analysis. Results: The addition of L-Arg and NCG enhanced the growth of weanling and young rabbit by increasing the nitrogen metabolism, protein efficiency ratio, and biological value, as well as feed intake and daily weight gain. Both L-Arg and NCG increased the concentration of immunoglobulin A (IgA), IgM, and IgG. NCG was superior to L-Arg in promoting intestinal villus development by increasing villus height, villus height/crypt depth index, and reducing the crypt depth. The effects of L-Arg and NCG on the cecal bacterial flora were mainly concentrated in different genera, including Parabacteroides, Roseburia, dgA-11_gut_group, Alistipes, Bacteroides, and Ruminococcaceae_UCG-005. These bacteria function mainly in amino acid transport and metabolism, energy production and conversion, lipid transport and metabolism, recombination and repair, cell cycle control, cell division, and cell motility. Conclusion: L-Arg and NCG can promote the growth and immunity of weanling and young JWR, as well as effecting the jejunum and ileum villi. L-Arg and NCG have different effects in the promotion of nutrient utilization, relieving inflammation and enhancing adaptability through regulating microbial community.

• International Journal of Oral Biology
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• v.33 no.4
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• pp.163-177
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• 2008

Periodontal disease, a form of chronic inflammatory bacterial infectious disease, is known to be a risk factor for cardiovascular disease (CVD). Porphyromonas gingivalis has been implicated in periodontal disease and widely studied for its role in the pathogenesis of CVD. A previous study demonstrating that periodontopathic P. gingivalis is involved in CVD showed that invasion of endothelial cells by the bacterium is accompanied by an increase in cytokine production, which may result in vascular atherosclerotic changes. The present study was performed in order to further elucidate the role of P. gingivalis in the process of atherosclerosis and CVD. For this purpose, invasion of human aortic smooth muscle cells (HASMC) by P. gingivalis 381 and its isogenic mutants of KDP150 ($fimA^-$), CW120 ($ppk^-$) and KS7 ($relA^-$) was assessed using a metronidazole protection assay. Wild type P. gingivalis invaded HASMCs with an efficiency of 0.12%. In contrast, KDP150 failed to demonstrate any invasive ability. CW120 and KS7 showed relatively higher invasion efficiencies, but results for these variants were still negligible when compared to the wild type invasiveness. These results suggest that fimbriae are required for invasion and that energy metabolism in association with regulatory genes involved in stress and stringent response may also be important for this process. ELISA assays revealed that the invasive P. gingivalis 381 increased production of the proinflammatory cytokine interleukin (IL)-$1{\beta}$ and the chemotactic cytokines (chemokine) IL (interleukin)-8 and monocyte chemotactic (MCP) protein-1 during the 30-90 min incubation periods (P<0.05). Expression of RANTES (regulation upon activation, normal T cell expressed and secreted) and Toll-like receptor (TLR)-4, a pattern recognition receptor (PRR), was increased in HASMCs infected with P. gingivalis 381 by RT-PCR analysis. P. gingivalis infection did not alter interferon-$\gamma$-inducible protein-10 expression in HASMCs. HASMC nonspecific necrosis and apoptotic cell death were measured by lactate dehydrogenase (LDH) and caspase activity assays, respectively. LDH release from HASMCs and HAMC caspase activity were significantly higher after a 90 min incubation with P. gingivalis 381. Taken together, P. gingivalis invasion of HASMCs induces inflammatory cytokine production, apoptotic cell death, and expression of TLR-4, a PRR which may react with the bacterial molecules and induce the expression of the chemokines IL-8, MCP-1 and RANTES. Overall, these results suggest that invasive P. gingivalis may participate in the pathogenesis of atherosclerosis, leading to CVD.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.6
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• pp.632-638
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• 2014

Nowadays, as part of an effort to increase the efficiency of propulsion shafting system, the revolution of the main diesel engine in CMCR(Contract Maximum Continuous Rating) is reduced whereas the stiffness of hull structure supporting the main diesel engine is relatively flexible. However, vibration problems related with resonant response of main diesel engine are increasing although top bracing is installed between the main diesel engine and the hull structures to increase natural frequency of engine body above CMCR to avoid resonant phenomenon. In this study, the dynamic characteristic of top bracing is reviewed by analyzing measuring results of general cargo ships which apply the hydraulic type instead of the friction type to control the natural frequency and the vibration of the engine body. Moreover, considering the vibration characteristic of the engine body and the hydraulic type of the top bracing by varying the number of top bracing, authors suggest the more effective way to control the vibration of the engine body despite of lower stiffness of the hull structure than in the past when the hydraulic type of top bracing is used.

• Korean Journal of Construction Engineering and Management
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• v.12 no.3
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• pp.42-52
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• 2011

As environmental issues are rising recently efforts to reduce environmental stress are emerging in all industry segments. Especially environmental impact of buildings occupy a critical portion, so each country is operating green building rating system for life cycle of buildings. Accordingly green building rating system for every facility is operating in Korea. And acquisition of grade I for building energy efficiency is mandatory for every new public buildings since 2010. To design green building efficiently and systematically eco-friendly elements should be considered and checked from the schematic design phase. But in many cases eco-friendly elements are checked at the end of constructed design phase. So applying eco-friendly elements at the value engineering process, which is performing through schematic and constructed design phase, could make a efficient and systematic green building design. Value engineering process is divided into pre workshop, workshop and post workshop stages. And subject selection in pre workshop stage is the step that finds out the subjects which has the great possibility to be improved to perform efficient value engineering workshop. So this study present the Green VE subject selection model to select the most considerable eco-friendly subjects in projects.

• Korean Chemical Engineering Research
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• v.55 no.4
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• pp.535-541
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• 2017

On the basis of 200 ppm of Ag and 120 l/h of feed flow rate, we built a pilot plant of an ion exchange fiber system having an double tube type ion exchange chamber with strong base ion exchange fiber (FIVAN A-6) which was designed to replace fibers easily and to eliminate the need for a fixture. The following results were obtained for the double tube type of ion exchange fiber system with an ion exchange capacity of 4.6 meq/g for Ag. The adsorption process was operated in the range of 40~90 l/h after confirming the effect of the flow rate and, pH did not affect formation of complex ion of Ag in the range of pH 7~12. In the case of backwash process, the recovery rate of Ag was tested in the range of 60~120 l/h and comparative experiments were carried out using NaOH, $NH_4Cl$, and NaCl as the chemicals for backwash. Although the desorption time was shortened at higher concentration, the desorption efficiency per mol was lowered. Therefore, it was confirmed that the desorption time and the concentration should be well balanced to operate economically. The desorption pattern of the backwash process is slower than the adsorption process and takes a lot of time. The results showed that the Ag adsorption ratio was 99.5% or more and the Ag recovery ratio was 96% or more, and commercialization was possible.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.23-30
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• 2016

In this study, the heat transfer and pressure drop characteristics were evaluated for multi-tube $CO_2$ water heaters with lengths of 4.5 m and 7.5 m. The evaluation was done using the -NTU method, and the results were compared with experimental data. Water flows through the shell side of the water heater, while $CO_2$ flows through 8 inner tubes. The heater uses a counter-current design to maximize the heat transfer efficiency. The energy balance equation describing the flows of $CO_2$ and water for each node is set up using the section-by-section method. The calculated heat transfer rates agree well with the experimental data within ${\pm}5%$ error. The outlet water temperature decreased linearly with the increase of the water flow rate. The calculated heat transfer rates agreed well with the experimental data within ${\pm}3%$ error. The results show that the heat transfer rate increases almost linearly with the increase of water flow rate or $CO_2$ inlet temperature in both the 4.5-m and 7.5-m water heaters, whereas the water outlet temperature linearly decreases with the increase of the water flow rate. The comparison of the $CO_2$ pressure drop between the calculation and experiment results shows good agreement at the high $CO_2$ flow rate within 5 % error, but the value is about 20 % higher in the experimental pressure drop at the low $CO_2$ flow rate.

• The KIPS Transactions:PartA
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• v.17A no.6
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• pp.265-274
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• 2010

As the process technology scales down and integration densities continue to increase, interconnection has become one of the most important factors in performance of recent multi-core processors. Recently, to reduce the delay due to interconnection, 3D architecture has been adopted in designing multi-core processors. In 3D multi-core processors, multiple cores are stacked vertically and each core on different layers are connected by direct vertical TSVs(through-silicon vias). Compared to 2D multi-core architecture, 3D multi-core architecture reduces wire length significantly, leading to decreased interconnection delay and lower power consumption. Despite the benefits mentioned above, 3D design technique cannot be practical without proper solutions for hotspots due to high temperature. In this paper, we propose three floorplan schemes for reducing the peak temperature in 3D multi-core processors. According to our simulation results, the proposed floorplan schemes are expected to mitigate the thermal problems of 3D multi-core processors efficiently, resulting in improved reliability. Moreover, processor performance improves by reducing the performance degradation due to DTM techniques. Power consumption also can be reduced by decreased temperature and reduced execution time.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11B
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• pp.1133-1141
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• 2009

In this paper, we present a distributed fault-tolerant topology control protocol that configure a wireless sensor network to achieve k-connectivity and (k+1)-coverage. One fundamental issue in sensor networks is to maintain both sensing coverage and network connectivity in order to support different applications and environments, while some least active nodes are on duty. Topology control algorithms have been proposed to maintain network connectivity while improving energy efficiency and increasing network capacity. However, by reducing the number of links in the network, topology control algorithms actually decrease the degree of routing redundancy. Although the protocols for resolving such a problem while maintaining sensing coverage were proposed, they requires accurate location information to check the coverage, and most of active sensors in the constructed topology maintain 2k-connectivity when they keep k-coverage. We propose the fault-tolerant topology control protocol that is based on the theorem that k-connectivity implies (k+1)-coverage when the sensing range is at two times the transmission range. The proposed distributed algorithm does not need accurate location information, the complexity is O(1). We demonstrate the capability of the proposed protocol to provide guaranteed connectivity and coverage, through both geometric analysis and extensive simulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.4
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• pp.596-601
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• 2020

Silicon carbide is considered a potentially useful material for high-temperature electronic devices because of its large band gap energy and p-type or n-type conduction that can be controlled by impurity doping. Accordingly, the thermoelectric properties of -SiC powder prepared by refined diatomite were investigated for high value-added applications of natural diatomite. -SiC powder was synthesized by a carbothermal reduction of the SiO₂ in refined diatomite using carbon black. An acid-treatment process was then performed to eliminate the remaining impurities (Fe, Ca, etc.). n-Type semiconductors were fabricated by sintering the pressed powder at 2000℃ for 1~5h in an N2 atmosphere. The electrical conductivity increased with increasing sintering time, which might be due to an increase in carrier concentration and improvement in grain-to-grain connectivity. The carrier compensation effect caused by the remaining acceptor impurities (Al, etc.) in the obtained -SiC had a deleterious influence on the electrical conductivity. The absolute value of the Seebeck coefficient increased with increasing sintering time, which might be due to a decrease in the stacking fault density accompanied by grain or crystallite growth. On the other hand, the power factor, which reflects the thermoelectric conversion efficiency of the present work, was slightly lower than that of the porous SiC semiconductors fabricated by conventional high-purity -SiC powder, it can be stated that the thermoelectric properties could be improved further by precise control of an acid-treatment process.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.3
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• pp.31-37
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• 2018

This study evaluates the dynamic tensile behavior of HPFRCC according to compressive strength levels of 100, 140 and 180 MPa. Firstly, the compressive stress-strain relationship of 100, 140 and 180 MPa class HPFRCC was analyzed. As a result, the compressive strengths were 112, 150 and 202 MPa, respectively, and the elastic modulus increased with increasing compressive strength. The static tensile strengths of HPFRCC of 100, 140 and 180 MPa were 10.7, 11.5 and 16.5 MPa, and tensile strength also increased with increasing compressive strength. On the other hand, static tensile strength and energy absorption capacity at 100 and 140 MPa class HPFRCC showed no significant difference according to the compressive strength level. It was influenced by the specification of specimen and the arrangement of steel fiber. As a result of evaluating the dynamic impact tensile strength of HPFRCC, tensile strength and dynamic impact factor of all HPFRCCs tended to increase with increasing strain rate from 10-1/s to 150/s. In the same strain rate range, the DIF of the tensile strength was measured higher as the compressive strength of HPFRCC was lower. It is considered that HPFRCC of 100 MPa is the best in terms of efficiency. Therefore, it is advantageous to use HPFRCC with high compressive strength when a high level of tensile performance is required, and it is preferable to use HPFRCC close to the target compressive strength for more efficient approach at a high strain rate such as explosion.