• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.4
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• pp.246-261
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• 2023

We investigated critical temperature for early marginal transplanting (CT-EMT) of the contemporary japonica rice varieties in Korea through the field, pot seedling tray, and the phytotron experiments during 2020 to 2023. The lowest mean temperature for 10 days from transplanting (MT-10DFT) that resulted in earlier heading date was 12.4℃ and the highest MT-10DFT that did not show the earlier heading date was 12.0℃ in the field study when the MT-10DFT varied by changing transplanting date. The lowest MT-10DFT that induced the increased biomass but not the earlier heading date was 11.6℃ and the highest MT-10DFT that showed neither the increased biomass nor the earlier heading date was 11.4℃. Compared to the 10-day later transplanting, the dates of the first root development, initiation of the chlorophyll recovery, and the first tiller development were earlier when the MT-10DFT was 9.1℃ or higher, 10.5℃ or higher, and 11.6℃ or higher, respectively, in the pot seedling tray and field experiments. The earliness of the first tiller development was a practical index for the estimation of CT-EMT during the early growth stage of rice. The response of transplanted rice to temperature treatments with the diurnal change of 10℃ in the phytotron study was similar to that shown in the field study. The data shown for constant temperature without a diurnal change revealed that the extent of positive effects of high temperature at day-time was greater than the extent of negative effects of low temperature at night-time on the early growth of transplanted rice. It was concluded that the critical MT-10DFT for early marginal transplanting of japonica rice in the temperate environments was between 11.4 to 11.6℃ based on the plant growth and between 12.0 to 12.4℃ based on the plant development.

• Journal of Digital Convergence
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• v.13 no.11
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• pp.197-204
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• 2015

This study aims to identify the effects: quality of chest compressions, height and weight of pregnant women cardiac arrest while lying $30^{\circ}$ inclined to the left has on the quality of chest compressions administered by 119 EMT. For the purpose of this study, 62 members of 119 EMTs in M, N, S, Y cities and G cities of J province agreed to join in the test and the test was conducted from June 15 to 16 in 2015. Two mannequins (Resusci Anne$^{(R)}$) were used for the study and the chest compression process was recorded with the use of the Laerdal PC Skill Reporting System$^{(R)}$. As a result, it was discovered that for patients with a $30^{\circ}$ left inclination, who were below 170 cm in height and 65 kg in weight, the proper frequency and depth of compression were unsatisfactory. With this in mind, training programs and instruments that can improve the quality of chest compressions depending on a person's (patient's) height and weight should be developed.

• Fire Science and Engineering
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• v.28 no.4
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• pp.104-111
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• 2014

The purpose of this study is to investigate the CPR within ambulance. The Subjects were 890 emergency medical technicians in fire department in Gyeonggido. After continuing education program, the emergency medical technicians completed the questionnaires from January to February, 2012. Questionnaire consisted of demographic characteristics, method of chest compression (one handed or two handed), chest compression - ventilation ratio, and hands only CPR. Data were analyzed by frequency analysis and Chi-square test, t-test. One-way analysis of variance (ANOVA) was followed by Scheffe post-hoc test to analyze changes in all parameters between all groups. One handed chest compression accounted for 14.0% and two handed chest compression accounted for 86.0%. Hands only CPR accounted for 71.7% and standard CPR (30:2) accounted for 28.3%. In order to perform the high quality CPR, as least three persons must be dispatched in the ambulance. The flexible management of manpower may improve the survival from the cardiac arrest. A systemic approach for educating and training EMT's in CPR is needed.

• Biomolecules & Therapeutics
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• v.24 no.2
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• pp.132-139
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• 2016

The endothelial-mesenchymal transition (EndMT) is known to be involved in the transformation of vascular endothelial cells to mesenchymal cells. EndMT has been confirmed that occur in various pathologic conditions. Transforming growth factor ${\beta}1$ (TGF-${\beta}1$) is a potent stimulator of the vascular endothelial to mesenchymal transition (EMT). Aspirin-triggered resolvin D1 (AT-RvD1) has been known to be involved in the resolution of inflammation, but whether it has effects on TGF-${\beta}1$-induced EndMT is not yet clear. Therefore, we investigated the effects of AT-RvD1 on the EndMT of human umbilical vein vascular endothelial cells line (HUVECs). Treatment with TGF-${\beta}1$ reduced the expression of Nrf2 and enhanced the level of F-actin, which is associated with paracellular permeability. The expression of endothelial marker VE-cadherin in HUVEC cells was reduced, and the expression of mesenchymal marker vimentin was enhanced. AT-RvD1 restored the expression of Nrf2 and vimentin and enhanced the expression of VE-cadherin. AT-RvD1 did also affect the migration of HUVEC cells. Inhibitory ${\kappa}B$ kinase 16 (IKK 16), which is known to inhibit the NF-${\kappa}B$ pathway, had an ability to increase the expression of Nrf2 and was associated with the inhibition effect of AT-RvD1 on TGF-${\beta}1$-induced EndMT, but it had no effect on TGF-${\beta}1$-induced EndMT alone. Smad7, which is a key regulator of TGF-${\beta}$/Smads signaling by negative feedback loops, was significantly increased with the treatment of AT-RvD1. These results suggest the possibility that AT-RvD1 suppresses the TGF-${\beta}1$-induced EndMT through increasing the expression of Smad7 and is closely related to oxidative stress.

• Journal of Life Science
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• v.28 no.1
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• pp.116-129
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• 2018

Living creatures possess long-conserved mechanisms to maintain homeostasis in response to various stresses. However, chronic and continuous exposure to stress can result in the excessive production of stress hormones, including catecholamines, which have harmful effects on health. Studies on the relationship between the sympathetic nervous system (SNS) and cancer have been conducted based on the traditional hypothesis that stress can promote cancer progression. Many preclinical and epidemiological studies have suggested that the regulation of ${\beta}$-adrenergic signaling, which mediates SNS activity, can suppress the progression of solid tumors. SNS activation has highly pleiotropic effects on tumor biology, as it stimulates oncogenes, survival pathways, the epithelial - mesenchymal transition, and invasion. Moreover, it inhibits DNA repair and programmed cell death and regulates the tumor microenvironment, including immune cells, endothelial cells, the extracellular matrix, mesenchymal cells, and adipocytes. Although targeted therapies on the molecular basis of tumor proliferation are currently receiving increased attention, they have clinical limitations, such as the compensatory activation of other signaling pathways, emergence of drug resistance, and various side effects, which raise the need for pleiotropic cancer regulation. This review summarizes the effects of the SNS on the development and progression of cancer and discusses the clinical perspectives of ${\beta}$-blockade as a novel therapeutic strategy for this disease.

• Journal of Life Science
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• v.30 no.5
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• pp.483-490
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• 2020

The ubiquitin system uses ligases and deubiquitinases (DUBs) to regulate ubiquitin position on protein substrates and is involved in many biological processes which determine stability, activity, and interaction of the target substrate. DUBs are classified in six groups according to catalytic domain, namely ubiquitin-specific proteases (USPs); ubiquitin C-terminal hydrolases (UCHs); ovarian tumor proteases (OTUs); Machado Joseph Disease proteases (MJDs); motif interacting with Ub (MIU)-containing novel DUB family (MINDY); and Jab1/MPN/MOV34 metalloenzymes (JAMMs). Otubain 1 (OTUB1) is a DUB in the OTU family which possesses both canonical and non-canonical activity and can regulate multiple cellular signaling pathways. In this review, we describe the function of OTUB1 through regulation of its canonical and non-canonical activities in multiple specifically cancer-associated pathways. The canonical activity of OTUB1 inhibits protein ubiquitination by cleaving Lys48 linkages while its non-canonical activity prevents ubiquitin transfer onto target proteins through binding to E2-conjugating enzymes, resulting in the induction of protein deubiquitination. OTUB1 can therefore canonically and non-canonically promote tumor cell proliferation, invasion, and drug resistance through regulating FOXM1, ERα, KRAS, p53, and mTORC1. Moreover, clinical research has demonstrated that OTUB1 overexpresses with high metastasis in many tumor types including breast, ovarian, esophageal squamous, and glioma. Therefore, OTUB1 has been suggested as a diagnosis marker and potential therapeutic target for oncotherapy.

• Journal of the Society of Disaster Information
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• v.12 no.4
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• pp.389-402
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• 2016

This research is about Department of Emergency medical services students' cognition type of female 119 paramedics. The purpose of this research is to understand department of emergency medical servises students' cognition of female 119 paramedics and identify characteristics classified by types. To this end, applying Q-method, this research objectively analyzes 72 department of emergency medical services students' reaction who complete the field training about ambulance about female 119 paramedics. The result of the department of emergency medical services students recognized type of female 119 paramedics could be typed into four types. The type I is recognized as "Stamina limit type", the type II as "expert type", the type III as "guardian angel type", and the type IV as "feminine experience type". The type I has 28.3%, the type II has 12.7%, the type III has 6%, and the type IV has 3.8% explanation power, and these explain 51% of total variable. Generally department of emergency medical services students' cognition of female 119 paramedic is that they are expert in first aid but students' cognition is negative because of female 119 paramedic's limit of stamina, exposure to danger, and giving birth and infant care thus we should arrange solution of these cognition.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.4
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• pp.1709-1717
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• 2013

This study was to identify the frequency and related factors of advanced airway management for patients with cardiac arrest by the Level 1 emergency medical technicians in the 119 Emergency medical service. 95 level-1 medical technicians belonging to Gwangju Fire Service Headquarter were surveyed with structured questionnaire composed of general and job-related characteristics, self-efficacy, barrier factors to performing the advanced airway for patients with cardiac arrest. From January 1, 2010 to June 30, 2011, data obtained from the Gwangju Fire Service Headquarter by performance of advanced airway. Self-efficacy toward the necessity of advanced airway revealed positive correlation with self-confidence. The barrier factor to advanced airway performance had negative correlation with the frequency of performance. The most important factor of advanced airway performance was necessity and self-efficacy. In conclusion, it is necessary to develop the field-based practice education program and to improve self-efficacy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.589-596
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• 2017

The purpose of this study was to investigate factors affecting employment stress among Emergency Department students and reduce stress of employment. A questionnaire survey was administered to 276 students who experienced clinical practice among 4 emergency college students in Jeollabuk-do and Jeollanam-do at 4-year and 3-year colleges from September 10 to 15, 2017. Statistical analysis was performed using the SPSS 18.0 program and analyzed by t-test, ANOVA, Pearson's correlation coefficient, and multiple regression analysis. In the results, there were significantly negative correlations between clinical training stress and major satisfaction (r=-0.192, p=0.001), significantly positive correlations between career stress and clinical training stress (r=0.222, p<0.001), and significantly negative correlations between career stress and major satisfaction (r=-0.245, p<0.001). In the multi-regression analysis, the following was discovered: higher clinical training stress (${\beta}=0.157$, p=0.005), lower major satisfaction (${\beta}=-0.211$, p<0.001), and higher career stress. Junior students (${\beta}=0.237$, p<0.001) and senior students (${\beta}=0.288$, p<0.001) had the highest career stress. Subjects with medium-level financial status had high career stress (${\beta}=0.173$, p=0.012). Therefore, this study suggests that colleges should reduce clinical training stress among emergency medical technology students, and more job support centers should be opened and job management programs developed.

• Journal of dental hygiene science
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• v.8 no.4
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• pp.381-386
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• 2008

This study was to examine the knowledge, attitude, self-efficacy, and capability of skill for Dept. of Dental Hygiene students in performing basic skill of cardiopulmonary resuscitation as the following AHA's CPR 2005 Guide-Lines. And we hope to know the influence of those affect on the correctness of chest thrusts, the correctness of artificial respiration, and the correctness of skill performing. As a SPSS 14.0 program's analyzing results, we came to the following conclusions : 1. In the basic CPR's knowledge, the scores of knowledge rose from 5.93 before education to 12.46 after education. In attitude, the scores of attitude rose from 2.52 to 3.71 after education. In self-efficacy's scores, rose from 3.22 to 3.26 too, and all components have statistically significant differences(P < .05). 2. In performing CPR, the correctness of chest thrusts is 68.90%, artificial respiration is 19.00%. 3. Total average score of the capability of skill is 4.51. 4. Only self-efficacy affected the correctness of chest thrusts after education(P < .05). 5. Attitude after education affected both the correctness of artificial respiration and skill performing(P < .05).