Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7 and Is Closely Related to Oxidative Stress |
Shu, Yusheng
(Department of Cardiothoracic Surgery, Clinical Medicine College of Yangzhou University, Subei People's Hospital)
Liu, Yu (Department of Cardiothoracic Surgery, Clinical Medicine College of Yangzhou University, Subei People's Hospital) Li, Xinxin (Department of Cardiothoracic Surgery, Subei People's Hospital) Cao, Ling (Department of Endocrinology, Clinical Medicine College of Yangzhou University, Subei People's Hospital) Yuan, Xiaolong (Department of Cardiothoracic Surgery, Clinical Medicine College of Yangzhou University, Subei People's Hospital) Li, Wenhui (Department of Cardiothoracic Surgery, Clinical Medicine College of Yangzhou University, Subei People's Hospital) Cao, Qianqian (Department of Cardiothoracic Surgery, Subei People's Hospital) |
1 | Zhang, X., Wang, T., Gui, P., Yao, C., Sun, W., Wang, L., Wang, H., Xie, W., Yao, S., Lin, Y. and Wu, Q. (2013) Resolvin D1 reverts lipopolysaccharide-induced TJ proteins disruption and the increase of cellular permeability by regulating signaling in human vascular endothelial cells. Oxid. Med. Cell. Longev. 2013, 185715. |
2 | Allen, M. and Louise Jones, J. (2011) Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J. Pathol. 223, 162-176. |
3 | Aisagbonhi, O., Rai, M., Ryzhov, S., Atria, N., Feoktistov, I. and Hatzopoulos, A. K. (2011) Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition. Dis. Model. Mech. 4, 469-483. DOI |
4 | Anastasiou, D., Poulogiannis, G., Asara, J. M., Boxer, M. B., Jiang, J. K., Shen, M., Bellinger, G., Sasaki, A, T., Locasale, J, W., Auld, D,S., Thomas, C,J., Heiden, M, G, V. and Cantley, L. C. (2011) Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science 334, 1278-1283. DOI |
5 | Benton, R. L., Maddie, M. A., Dincman, T. A., Hagg, T. and Whittemore, S. R. (2009) Transcriptional activation of endothelial cells by coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury. ASN Neuro. 1, 181-184. DOI |
6 | Churchman, A. T., Anwar, A. A., Li, F. Y., Sato, H., Ishii, T., Mann, G. E. and Siow, R. (2009) Transforming growth factor-1 elicits Nrf2-mediated antioxidant responses in aortic smooth muscle cells. J. Cell. Mol. Med. 13, 2282-2292. DOI |
7 | Cox, Jr, R., Phillips, O., Fukumoto, J., Fukumoto, I., Tamarapu Parthasarathy, P., Arias, S., Cho, Y., Lockey, R. F. and Kolliputi, N. (2015) Aspirin-Triggered Resolvin D1 Treatment Enhances Resolution of Hyperoxic Acute Lung Injury. Am. J. Respir. Cell Mol. Biol. 53, 422-435. DOI |
8 | Choi, H. Y., Lee, H. G., Kim, B. S., Ahn, S. H., Jung, A., Lee, M., Lee, J.E., Kim, H. J., Ha, S. K. and Park, H. C. (2015) Mesenchymal stem cell-derived microparticles ameliorate peritubular capillary rarefaction via inhibition of endothelial-mesenchymal transition and decrease tubulointerstitial fibrosis in unilateral ureteral obstruction. Stem Cell Res. Ther. 6, 18. DOI |
9 | Edens, H. A. and Parkos, C. A. (2000) Modulation of epithelial and endothelial paracellular permeability by leukocytes. Adv. Drug Deliv. Rev. 41, 315-328. DOI |
10 | Emmanuel, C., Huynh, M., Matthews, J., Kelly, E. and Zoellner, H. (2013) TNF- and TGF- synergistically stimulate elongation of human endothelial cells without transdifferentiation to smooth muscle cell phenotype. Cytokine 61, 38-40. DOI |
11 | Garside, V. C., Chang, A. C., Karsan, A. and Hoodless, P. A. (2013) Co-ordinating Notch, BMP, and TGF- signaling during heart valve development. Cell. Mol. Life Sci. 70, 2899-2917. DOI |
12 | Gonzalez, D. M. and Medici, D. (2014) Signaling mechanisms of the epithelial-mesenchymal transition. Sci. Signal. 7, re8. DOI |
13 | Jaffe, E. A., Nachman, R. L., Becker, C. G. and Minick, C. R. (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52, 2745-2756. DOI |
14 | Goumans, M. J., Valdimarsdottir, G., Itoh, S., Lebrin, F., Larsson, J., Mummery, C., Karlsson, S. and ten Dijke, P. (2003) Activin receptor-like kinase (ALK) 1 is an antagonistic mediator of lateral / ALK5 signaling. Mol. Cell 12, 817-828. DOI |
15 | Harrison, J. L., Rowe, R. K., Ellis, T. W., Yee, N. S., O'Hara, B. F., Adelson, P. D. and Lifshitz, J. (2015) Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse. Brain Behav. Immun. 47, 131-140. DOI |
16 | Inoue, Y. and Imamura, T. (2008) Regulation of TGF- family signaling by E3 ubiquitin ligases. Cancer Sci. 99, 2107-2112. DOI |
17 | Krizbai, I. A., Gasparics, A., Nagyoszi, P., Fazakas, C., Molnar, J., Wilhelm, I., Bencs R,. Rosivall L. and Sebe, A. (2015) Endothelial-Mesenchymal Transition of Brain Endothelial Cells: Possible Role during Metastatic Extravasation. PLoS One 10, e0119655. DOI |
18 | Kevil, C. G., Oshima, T., Alexander, B., Coe, L. L. and Alexander, J. S. (2000) -mediated permeability: role of MAPK and occludin. Am. J. Physiol. Cell Physiol. 279, C21-C30. DOI |
19 | Kobayashi, M. and Yamamoto, M. (2005) Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid. Redox Signal. 7, 385-394. DOI |
20 | Kashihara, N., Haruna, Y., Kondeti, V. K. and Kanwar, Y. S. (2010) Oxidative stress in diabetic nephropathy. Curr. Med. Chem. 17, 4256-4269. DOI |
21 | Ng, Y. Y., Hou, C. C., Wang, W., Huang, X. R. and Lan, H. Y. (2005) Blockade of activation and renal inflammation by ultrasoundmediated gene transfer of Smad7 in rat remnant kidney. Kidney Int. Suppl. 67, S83-S91. DOI |
22 | Kaneda, H., Arao, T., Matsumoto, K., De Velasco, M. A., Tamura, D., Aomatsu, K., Kudo, K., Sakai, K., Nagai, T., Fujita, Y., Tanaka, K., Yanagihara, K., Yamada, Y., Okamato, I., Nakagawa, K. and Nishio, K. (2011) Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer. Br. J. Cancer 105, 1210-1217. DOI |
23 | Lee, H. J., Park, M. K., Lee, E. J. and Lee, C. H. (2013) Resolvin D1 inhibits TGF--induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32. Int. J. Biochem. Cell Biol. 45, 2801-2807. DOI |
24 | Medici, D., Shore, E. M., Lounev, V. Y., Kaplan, F. S., Kalluri, R. and Olsen, B. R. (2010) Conversion of vascular endothelial cells into multipotent stem-like cells. Nat. Med. 16, 1400-1406. DOI |
25 | Ryoo, I. G., Ha, H. and Kwak, M. K. (2014) Inhibitory role of the KEAP1- NRF2 pathway in -stimulated renal epithelial transition to fibroblastic cells: a modulatory effect on SMAD signaling. PLoS One 9, e93265. DOI |
26 | Shu, Y. S., Tao, W., Miao, Q. B., Zhu, Y. B. and Yang, Y. F. (2014) Improvement of ventilation-induced lung injury in a rodent model by inhibition of inhibitory kinase. J. Trauma Acute. Care Surg. 76, 1417-1424. DOI |
27 | Serhan, C. N., Hong, S., Gronert, K., Colgan, S. P., Devchand, P. R., Mirick, G. and Moussignac, R. L. (2002) Resolvins a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196, 1025-1037. DOI |
28 | Van Meeteren, L. A. and Ten Dijke, P. (2012) Regulation of endothelial cell plasticity by TGF-. Cell Tissue Res. 347, 177-186. DOI |
29 | Spite, M., Norling, L. V., Summers, L., Yang, R., Cooper, D., Petasis, N. A., Flower, R. J., Perretti, M. and Serhan, C. N. (2009) Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 461, 1287-1291. DOI |
30 | Thiery, J. P. (2003) Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 15, 740-746. DOI |
31 | Wu, S. H., Zhang, Y. M., Tao, H. X. and Dong, L. (2010) Lipoxin A4 inhibits transition of epithelial to mesenchymal cells in proximal tubules. Am. J. Nephrol. 32, 122-136. DOI |
32 | Xiao, L., Kim, D. J., Davis, C. L., McCann, J. V., Dunleavey, J. M., Vanderlinden, A. K., Xu, N., Pattenden, S. G., Frye, S. V., Xu, X., Onaitis, M., Monaghan-Benson, E., Burridge, K. and Dudley, A. C. (2015) Tumor endothelial cells with distinct patterns of - driven endothelial-to-mesenchymal transition. Cancer Res. 75, 1244-1254. DOI |
33 | Yao, Y., Jumabay, M., Ly, A., Radparvar, M., Cubberly, M. R. and Boström, K. I. (2013) A role for the endothelium in vascular calcification. Circ. Res. 113, 495-504. DOI |
34 | Yan, X., Liu, Z. and Chen, Y. (2009) Regulation of TGF- signaling by Smad7. Acta Biochim. Biophys. Sin. (Shanghai). 41, 263-272. DOI |
35 | Zeisberg, E. M., Potenta, S., Xie, L., Zeisberg, M. and Kalluri, R. (2007) Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res. 67, 10123-10128. DOI |