• Title/Summary/Keyword: EM1

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Identification of Novel SNPs in Bovine Insulin-like Growth Factor Binding Protein-3 (IGFBP3) Gene

  • Kim, J.Y.;Yoon, D.H.;Park, B.L.;Kim, L.H.;Na, K.J.;Choi, J.G.;Cho, C.Y.;Lee, H.K.;Chung, E.R.;Sang, B.C.;Cheong, I.J.;Oh, S.J.;Shin, Hyoung Doo
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.1
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    • pp.3-7
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    • 2005
  • The insulin-like growth factors (IGFs), their receptors, and their binding proteins play key roles in regulating cell proliferation and apoptosis. Insulin-like growth factor binding protein-3 (IGFBP3, OMIM #146732) is one of the proteins that bind to the IGFs. IGFBP3 is a modulator of IGF bioactivity, and direct growth inhibitor in the extravascular tissue compartment. We identified twenty-two novel single nucleotide polymorphisms (SNPs) in IGFBP3 gene in Korean cattle (Hanwoo, Bos taurus coreanae) by direct sequencing of full gene including -1,500 bp promoter region. Among the identified SNPs, five common SNPs were screened in 650 Korean cattle; one SNP in promoter (IGFBP3 G-854C), one in 5'UTR region (IGFBP3 G-100A), two in intron 1 (IGFBP3 G+421T, IGFBP3 T+1636A), and one in intron 2 (IGFBP3 C+3863A). The frequencies of each SNP were 0.357 (IGFBP3 G-854C), 0.472 (IGFBP3 G-100A), 0.418 (IGFBP3 G+421T), 0.363 (IGFBP3 T+1636A) and 0.226 (IGFBP3 C+3863A), respectively. Haplotypes and their frequencies were estimated by EM algorithm. Six haplotypes were constructed with five SNPs and linkage disequilibrium coefficients (|D'|) between SNP pairs were also calculated. The information on SNPs and haplotypes in IGFBP3 gene could be useful for genetic studies of this gene.

A Analysis on the Result of CE/CS Test on the KOMPSAT-I ETB (아리랑1호 위성 ETB의 전도성 전자파 환경 시험결과 분석)

  • 임성빈;천용식
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.2
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    • pp.184-192
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    • 2001
  • In this paper, we analyze the result of the conduced emission and susceptibility tests performed on the KOMPSAT-I ETB Platform. The ETB platform consists of the EM (Engineering Model) boxes developed to perform the electrical functional test. During the conducted emission test, we measured the instant waveform in time domain when each switch was turn on, and spectrum of the noise in the frequency range of 10 Hz up to100 MHz fur the steady state of the ETB. During the conducted susceptibility test, no malfunction and no serious damage of the electronic box were observed when a simulated noise waveform was applied to the DC power bus. The simulated waveform was obtained by adding the 6 dB-system margin to the worst case waveform measured from the conducted emission. This test was performed as co-development of the KOMPSAT-I with TRW in USA.

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AN ELECTROMYOGRAPHIC STUDY ON THE TREATMENT OF BRUXISM AND TEMPOROMANDIBULAR JOINT DYSFUNCTION PATIENTS (Bruxism과 악관절(顎關節) 기능장애자(機能障碍者)의 치료(治療)에 관(關)한 근전도학적(筋電圖學的) 연구(硏究))

  • Ro, Chang-Sup;Choi, Boo-Byung
    • The Journal of Korean Academy of Prosthodontics
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    • v.22 no.1
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    • pp.85-94
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    • 1984
  • The purpose of this study was to investigate treatment effectiveness of TENS and bite plane for bruxism and TMJ dysfunction patients. The electromyograms were made on males aged 23 to 25 with sound stomatognathic system, 5 males bruxism aged 24 to 27, and 1 male and 4 females TMJ dysfunction patients (right TMJ pain) aged 14 to 33. The electromyographic study was limited to the middle of masseter muscle and anterior temporal muscle. The electromyographic study was carried out with 8-channel EM2 (Myotronics Research Inc.) and was taken 5 mandibular positions of clinical rest position, clench intercuspal position, clench protruded, cluch right, clench left. The 2 pairs of surface electrodes were used exactly, with the ear lobe as reference point. The recording were subjected to determine the mean voltage. The results were as follows; 1. In the clinical rest position, the muscle activities of bruxism and TMJ dysfunction patients were higher than those of normal at the before treatment, but that were lower or similar to those of normal at the TENS after and after bite plane wearing. 2. In the clench I.C.P., the muscle activities of TMJ dysfunction patients were decreased as the order of the before treatment, after TENS, after occlusal bite plane wearing, but those of bruxism were irregular. 3. In the clench right and the clench left, the muscle activities of the middle of masseter muscle of the non-working side of bruxism were higher than those of the working side at the before treatment and after TENS, but the muscle activities of after occlusal bite plane wearing were similar to those of the normal. 4. In the clench right and the clench left, the muscle activities of the middle of masseter muscle and anterior temporal muscle of the working side of TMJ dysfunction patients were higher than those of non-working side as like the normal at the before treatment, after TENS, and after occlusal bite plane wearing.

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Relationships of Body Composition and Fat Partition with Body Condition Score in Serra da Estrela Ewes

  • Caldeira, R.M.;Portugal, A.V.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.7
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    • pp.1108-1114
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    • 2007
  • Twenty eight non-lactating and non-pregnant adult Serra da Estrela ewes, ranging in body condition score (BCS) from 1 to 4 were used to study the relationships between BCS, live weight (LW), body composition and fat partition. Ewes were slaughtered and their kidney knob and channel fat (KKCF), sternal fat (STF) and omental plus mesenteric fat (OMF) were separated and weighed. Left sides of carcasses as well as the respective lumbar joints were then dissected into muscle, bone and subcutaneous (SCF) and intermuscular fat (IMF). The relationship between LW and BCS was studied using data from 1,396 observations on 63 ewes from the same flock and it was found to be linear. Regression analysis was also used to describe the relationships among BCS and/or LW and weights (kg) and percentages in empty body weight (EBW) of dissected tissues. The prediction of weights and percentages in EBW of total fat (TF) and of all fat depots afforded by BCS was better than that provided by LW. Only the weight of muscle and the percentage of bone in the EBW were more efficiently predicted by LW than by BCS. IMF represented the largest fat depot with a BCS of 1 and 2, whereas SCF was the most important site of fat deposition with a BCS of 3 and 4. Allometric coefficients for each fat depot in TF suggest that the fat deposition order in ewes from this breed is: IMF, OMF, SCF and KKCF. Results demonstrate that BCS is a better predictor than LW of body reserves in this breed and that LJ is a suitable anatomical region to evaluate BCS.

Design and Realization of 20 GHz Push-Push FET Dielectric Resonator Oscillator (20 GHz Push-Push FET 유전체 공진기 발진기 설계 및 실현)

  • Jung, Jae Kwon;Kim, Ihn Seok
    • Journal of Advanced Navigation Technology
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    • v.6 no.1
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    • pp.52-62
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    • 2002
  • Electrical characteristics of two types of 20 GHz Push-Push GaAs MESFET dielectric resonator oscillators having Wilkinson and T-junction power combiners for the output stage have been investigated. The Push-Push oscillator for suppressing fundamental frequency 10 GHz and enhancing 20 GHz has been designed and realized in microstrip configuration on 20 mil thick RT-Duroid(${\varepsilon}_r$=2.52) teflon substrate. Two different types of power combiners, T-junction and Wilkinson, have been considered. Whenever one type of the combiners has been adopted for the output circuit, output power, phase noise and fundamental frequency suppression characteristics of the oscillator have been measured. When the Wilkinson power combiner was used, a maximum output power of 5.67 dBm, a phase noise of -105.5 dBc/Hz at an offset frequency of 100 kHz and a fundamental frequency suppression of -29.33 dBc have been measured. When the T-junction power combiner was used, a maximum output power of -1.17 dBm, a phase noise of -102.2 dBc/Hz at an offset frequency of 100 kHz and a fundamental frequency suppression of -17.84 dBc have been measured.

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The Relationship between Some Blood Parameters and Antioxidant Enzyme Activity in Korean Postmenopausal Women (일부 폐경 후 여성에서 영양상태 및 골대사 관련 일부 혈액 지표와 항산화효소 활성과의 관련성 분석)

  • Lee, Haeng-Shin;Kim, Mi-Hyun;Lee, Da-Hong;Sung, Chung-Ja
    • Journal of Nutrition and Health
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    • v.39 no.5
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    • pp.476-484
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    • 2006
  • To elucidate the relationship between blood parameters related bone metabolism and antioxidant enzyme activity in postmenopausal period 60 women residing in Iksan area were recruited. Food and nutrient intake of each individual subject were estimated by 24-hour recalls of 3 non-consecutive days. The biochemical markers including total protein, albumin, osteocalcin (intact bone gla protein; BOP), calcium, phosphorus and hemoglobin were measured in fasting blood. In addition, parameters of antioxidative capacity including the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx) , catalase (CAT) and total antioxidant capacity (TA) were monitored in blood, also. The mean age, height, weight, and BM! of subjects were 64.8 years, 151.1 em, 59.5 kg $26.0\;kg/m^2$, respectively. The mean SOD, GPx, and CAT activities were 138.5 U/ml, 1,273.8 U/ml and 314.3 kU/l respectively, and TA was 1.16 mmol/l without significant difference among different age groups. BMI was positively correlated with SOD activity (p < 0.01). SOD activity and CAT activity showed positive correlation with serum albumin (p < 0.05) and hemoglobin (p < 0.01). In conclusion, this study revealed that antioxidant enzyme activity holds a significant relationship with the blood parameters like as serum albumin and hemoglobin in postmenopausal women and further systematic research is needed to investigate the their relation mechanism.

Improvement of the access channel algorithm in the CDMA2000 system (CDMA2000시스템에 있어서 액세스채널 알고리즘 개선)

  • Lee Kwang jai;Chun Jong hun;Park Jong an
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.3B
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    • pp.138-143
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    • 2005
  • This paper aims to optimize an access probe algorithm for the CDMA 2000 system. The incremental value of PWR_STEP increases as NUM_STEP as 1dBm±0.2 for access probe of the area with good receiving sensitivity when the mobile station transmits via access channel and does not receive any ACK message. However, for the area with weak receiving sensitivity, according to the algorithm of open-loop power control, the transmitting power amplifier becomes saturated and PWR_STEP incremental value keeps performing access probe to 0dBm±0.2. Therefore interference and battery consumption increases according to the transmission of the mobile station. We have optimized the access probe algorithm according to the receiving sensitivity. We transmit the incremental value of access probe power, with delaying as much RT slot value as indicated by IS-95C standard in case of good receiving sensitivity and with delaying RT+l slot value in case of weak receiving sensitivity. Simulation results showed that the proposed algorithm contributes to decrease of the interference and battery consumption according to the transmitting power of the mobile station and improves the call duration.

Determination and survey of fluoroquinolones in meats and eggs (II) (식육 및 계란에서 플루오로퀴놀론계 항균물질 정량분석 및 잔류조사 (II))

  • Choi, Yoon-Hwa;Kim, Yeon-Ju;Lee, Kyung-Hye;Kang, Young-Il;Lee, Jung-Hark
    • Korean Journal of Veterinary Service
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    • v.32 no.3
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    • pp.281-286
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    • 2009
  • Fluoroquinolones in muscle and egg were separated by liquid extraction and determined. The analysis was carried out using following conditions; C18 column ($150{\times}4.6mm$, $5{\mu}m$), mobile phase composed of D.W. (containing 0.4% triethylamine and phosphoric acid) : methanol : acetonitrile (780:100:120, v/v/v), quarternary pump at a flow rate of 0.9ml/min and $20{\mu}l$ of injection volume, fluorescence detector with EX 278nm/Em 456nm. The calibration range of seven fluoroquinolones showed linearity ($r^2{\geq}0.999$) at concentration range of $0.025{\sim}0.8{\mu}g/ml$. The recoveries in fortified muscle and egg represented more than 81.3%. The detection limits for ofloxacin, norfloxacin, ciprofloxacin, enrofloxacin, danofloxacin, saraloxacin and orbifloxacin were 3.1, 2.5, 3.6, 1.7, 0.9, 2.5 and $2.1{\mu}g/kg$, respectively. We also monitored fluoroquinolones residue in the sample (chicken muscle 182, cattle muscle 140, pig muscle 139, egg 212) using EEC-plate (E. coli ATCC 11303) screening and HPLC confirmation methods. The screening test results, fluoroquinolones, antibacterial substances were all negative.

Feeding Habits of Acanthogobius luridus Inhabiting the Intertidal Zone of the Western Coast of Korea (서해연안 조간대에 서식하는 비늘흰발망둑, Acanthogobius luridus의 식성)

  • 김종연
    • Journal of Aquaculture
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    • v.13 no.4
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    • pp.309-316
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    • 2000
  • Feeding habits of A. luridus were studied by analyzing the stomach contents of monthly collected fish from the intertidal zone of Dodun-ri, Sochon from July 1996 to June 1997. Fullness of stomach increased twice a day, first in the morning and second in the afternoon. A. luridus (1.2-5.9 em in standard length) was a carnivore consuming mainly decapods (natantia larvae, Acetes japonicus, Penaeus japonicus and reptantia larvae), amphipods (caprellids, gammarids and hyperiids) and copepods (Acartia sp., Calanus sinicus, Corycaeus affinis, and Microsetella sp.). Its diets also included minor quantities of isopods, cirriped larvae, polychaete larvae and stomatopods. According to fish size, some changes in feeding habits were apparent, i.e. smaller fish preferred to prey in the following order : copepods < decapods < amphipods. However, as the size increased, decapods and amphipods were selected.

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SPATIAL AND ENERGY RESOLUTIONS OF A HEXAGONAL ANIMAL PET SCANNER BASED ON LGSO CRYSTAL AND FLAT-PANEL PMT

  • Lee, Chan-Mi;Hong, Seong-Jong;Yoon, Hyun-Suk;Ito, Mikiko;Kwon, Sun-Il;Park, Sang-Keun;Lee, Dong-Soo;Sim, Kwang-Souk;Lee, Jae-Sung
    • Nuclear Engineering and Technology
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    • v.44 no.1
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    • pp.53-60
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    • 2012
  • The aim of this study was to explore the spatial and energy resolutions of a PET scanner that we have recently developed. The scanner, which consists of six detector modules with 1-layer LGSO crystals, has a hexagonal configuration with a faceto- face distance of 86.4 mm between two opposite PET modules; such properties facilitate the imaging of small animals. A $^{22}Na$ point source was employed to estimate horizontal and vertical spatial resolutions. To assess the energy resolution, a uniform $^{18}F$ cylindrical phantom was scanned. A software-based spectrum analysis of list-mode data was used to assign a local energy window centered on the photopeak position for every single crystal. For the image reconstruction, an ML-EM algorithm was used. The spatial resolutions at the center of the scanner were 0.99 mm in the horizontal direction and 1.13 mm in the vertical direction. The energy resolution averaged over each PMT ranged from 13.3%-14.3%, which gave an average value of 13.8%. These results show that this simple system is promising for small animal imaging with excellent spatial and energy resolutions.