Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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The Relationship between Some Blood Parameters and Antioxidant Enzyme Activity in Korean Postmenopausal Women

일부 폐경 후 여성에서 영양상태 및 골대사 관련 일부 혈액 지표와 항산화효소 활성과의 관련성 분석

  • Lee, Haeng-Shin (Department of Food Industry, Korea Health Industry Development Institute) ;
  • Kim, Mi-Hyun (Department of Food & Nutrition, Kangwon National University) ;
  • Lee, Da-Hong (Department of Food & Nutrition, Wonkwang University) ;
  • Sung, Chung-Ja (Department of Food & Nutrition, Sookmyung Womnen's University)
  • 이행신 (한국보건산업진흥원 식품산업단) ;
  • 김미현 (강원대학교 식품영양학과) ;
  • 이다홍 (원광대학교 식품영양학과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • Published : 2006.07.31
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Abstract

To elucidate the relationship between blood parameters related bone metabolism and antioxidant enzyme activity in postmenopausal period 60 women residing in Iksan area were recruited. Food and nutrient intake of each individual subject were estimated by 24-hour recalls of 3 non-consecutive days. The biochemical markers including total protein, albumin, osteocalcin (intact bone gla protein; BOP), calcium, phosphorus and hemoglobin were measured in fasting blood. In addition, parameters of antioxidative capacity including the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx) , catalase (CAT) and total antioxidant capacity (TA) were monitored in blood, also. The mean age, height, weight, and BM! of subjects were 64.8 years, 151.1 em, 59.5 kg $26.0\;kg/m^2$, respectively. The mean SOD, GPx, and CAT activities were 138.5 U/ml, 1,273.8 U/ml and 314.3 kU/l respectively, and TA was 1.16 mmol/l without significant difference among different age groups. BMI was positively correlated with SOD activity (p < 0.01). SOD activity and CAT activity showed positive correlation with serum albumin (p < 0.05) and hemoglobin (p < 0.01). In conclusion, this study revealed that antioxidant enzyme activity holds a significant relationship with the blood parameters like as serum albumin and hemoglobin in postmenopausal women and further systematic research is needed to investigate the their relation mechanism.

Keywords

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