• Nuclear Engineering and Technology
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• v.25 no.1
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• pp.102-109
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• 1993

A PC-computer program RADAP has been developed in this study to perform a quick real-time analysis of dose assessment following an accident in a nuclear facility. RADAP uses an interactive LKagrangian puff model in simulating the transport and diffusion of radioactive plume in the atmosphere. For real-time analysis, RADAP treats one or multiple puffs of ground-level releases, simultaneously. It is assumed to maintain a Gaussian distribution within the puff and the diffusion coefficients are computed using the USNRC's normal sigma curve method. The program, however, does not consider the spatial variations but the temporal variations in wind conditions. Whole body and thyroid doses for 3$\times$31 grid are directed to output files, and they are also displayed through computer graphics on VGA or EGA color monitor. The results show that RADAP can be an excellent tool for quick estimation of accidental doses.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.12
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• pp.935-942
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• 2002

When designing fluid mounts, design parameters can be varied in order to obtain a desired notch frequency and notch depth. The notch frequency is a function of the mount parameters and is typically selected by the designer to occur at the vibration disturbance frequency. Since the process of choosing these parameters can involve some trial and error, it seems to be a great application for obtaining optimal performance of the mount. Many combinations of parameters are possible to give us the desired notch frequency, but the question is which combination provides the lowest depth. Therefore. an automatic optimal technique is needed to optimize the performance of the fluid mount. In this study. the enhanced genetic algorithm (EGA) is applied to minimizing transmissibility of a fluid mount at the desired notch frequency, and at the notch and resonant frequencies. The EGA is modified genetic algorithm to search global and local optimal solutions of multi-modal function optimization. Furthermore. to reduce the searching time as compare to conventional genetic algorithm and Increase the precision of the solutions, the modified simplex method is combined with the algorithm. The results show that the performance of the optimized mount by using the hybrid algorithm is better than that of the conventional fluid mount.

• Journal of Conservation Science
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• v.33 no.1
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• pp.51-59
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• 2017

Lacquer has been used as a natural paint or adhesive in Korea since 2nd century B.C. It has been found to have been used as an adhesive as mentioned in old records and as seen in excavated relics, It was also mixed with flour, animal glue, or fish glue to produce lacquer adhesives. Qualitative analysis and evaluation of the applicability of lacquer and additives was performed in this study. The results of EGA analysis for lacquer additives confirmed that the pyrolysis temperature of lacquer, glucose glue, and animal glue. On the basis of this result, raw lacquer sample was checked that pyrolysis product that originated from urushiol side chain (R group). Components originating from glucose and amino acid were detected in glutinous rice paste and animal glue samples. In this study, the optimum pyrolysis temperature for each lacquer and additive mixture was determined from basic qualitative analysis data. By performing the qualitative analysis of each mixture, the applicability of this technique for analyzing real relics was evaluated.

• Animal Bioscience
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• v.36 no.7
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• pp.1022-1033
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• 2023

Objective: p66Shc, a 66 kDa protein isoform encoded by the proto-oncogene SHC, is an essential intracellular redox homeostasis regulatory enzyme that is involved in the regulation of cellular oxidative stress, apoptosis induction and the occurrence of multiple age-related diseases. This study investigated the expression profile and functional characteristics of p66Shc during preimplantation embryo development in sheep. Methods: The expression pattern of p66Shc during preimplantation embryo development in sheep at the mRNA and protein levels were studied by quantitative real-time polymerase chain reaction (RT-qPCR) and immunofluorescence staining. The effect of p66Shc knockdown on the developmental potential were evaluated by cleavage rate, morula rate and blastocyst rate. The effect of p66Shc deficiency on reactive oxygen species (ROS) production, DNA oxidative damage and the expression of antioxidant enzymes (e.g., catalase and manganese superoxide dismutase [MnSOD]) were also investigated by immunofluorescence staining. Results: Our results showed that p66Shc mRNA and protein were expressed in all stages of sheep early embryos and that p66Shc mRNA was significantly downregulated in the 4-to 8-cell stage (p<0.05) and significantly upregulated in the morula and blastocyst stages after embryonic genome activation (EGA) (p<0.05). Immunofluorescence staining showed that the p66Shc protein was mainly located in the peripheral region of the blastomere cytoplasm at different stages of preimplantation embryonic development. Notably, serine (Ser36)-phosphorylated p66Shc localized only in the cytoplasm during the 2- to 8-cell stage prior to EGA, while phosphorylated (Ser36) p66Shc localized not only in the cytoplasm but also predominantly in the nucleus after EGA. RNAi-mediated silencing of p66Shc via microinjection of p66Shc siRNA into sheep zygotes resulted in significant decreases in p66Shc mRNA and protein levels (p<0.05). Knockdown of p66Shc resulted in significant declines in the levels of intracellular ROS (p<0.05) and the DNA damage marker 8-hydroxy2'-deoxyguanosine (p<0.05), markedly increased MnSOD levels (p<0.05) and resulted in a tendency to develop to the morula stage. Conclusion: These results indicate that p66Shc is involved in the metabolic regulation of ROS production and DNA oxidative damage during sheep early embryonic development.

• Journal of Environmental Health Sciences
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• v.5 no.1
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• pp.58-60
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• 1978

This experiment was carried out to determine the amount of organophosphorous pesticides accumulated in farmer's blood during the farming season. The Blood had been collected for about 5ml from farmer's, and extraction was purified on a Avicel/Darco G-Co (1:10) column and determined by Gas Chromatography using AFID supported on 2% EGA. The Gas chromatographic detection yielded recoveries from the blood of 88% for smithion 94% for malathion. The amount of average contamination shows 0.045ppm for smithion. 0.054ppm for malathion.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.1
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• pp.113-121
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• 1989

A software interface called CGI-K including device driver routines and graphics primitives for the grphic board "K" was designed, implemented in the Design Automation Laboratory of KAIST and installed on IBM PC/AT, using assembly and C language supported by TMS 34010 grphics processor. Several algorithms generating the graphics primitives such as box, circle, pie chord are proposed. The drawing speed of CGI-K on the graphic board K was found out to be three to ten times faster than that of the EGA for several examples. A 2-D graphics editor called GRIM (graphics input and modification) and a 3-dimensional graphics renderer called IPCHE which can draw 3-D objects were developed as two major application programs running on CGI-K. The graphics primitives supported in GRIM include polygon, box, circle, and ace. The IPCHE receives a 3-D objects data file and displays the 3-D object on the screen with hidden surface removal, shading, and perspective scaling.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.1
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• pp.8-13
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• 2016

A pattern-switchable origami antenna is designed with paper using inkjet-printing technology. The proposed antenna can be switched between loop and dipole antenna modes by folding and unfolding the paper, respectively. The proposed antenna is designed for the resonant frequencies of both modes to be 1.85 GHz. Eutectic gallium-indium liquid metal is introduced in order to avoid cracks in the conductive ink when the paper is folded. The performance of the proposed antenna is demonstrated through simulation and measurement results and antenna gain of dipole-mode and loop-mode are -4 dBi and -5 dBi, respectively. Also, the nulls of both dipole and loop modes compensate nulls from each mode.

• Journal of applied mathematics & informatics
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• v.31 no.5_6
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• pp.677-693
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• 2013

We construct exponentially fitted interpolation formulas using the values of the ${\omega}$-dependent function $f$ as well as its derivatives up to the $n$th order at a finite number of nodes on a closed interval ${\Omega}$. The function $f$ is of the form, $$f(x)=f_1(x)cos({\omega}x)+f_2(x)sin({\omega}x),x{\in}{\Omega}$$, where $f_1$ and $f_2$ are smooth enough to be approximated by polynomials on ${\Omega}$. Some properties of the formulas are newly found. The properties are numerically investigated and reexamined by producing some figures.

• YAKHAK HOEJI
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• v.41 no.3
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• pp.298-304
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• 1997

Molecular mechanics and conformation search methods were carried oyt to investigate the relationship between conformations and thromboxane synthetase ingibitory activities of om ega-pyridylalkenoic acids. The initial geometries of ${\omega}$-pyridylalkenoic acids and heme part of cytochrome P-450 were obtained from MM+ geometry optimization. The bond lenths and angles were not varied by step during the conformation searching. Stable conformers of some ${\omega}$-pyridylalkenoic acids were obtained by comformational search method. The distances were 8.5~10.8 ${\AA}$- between N atom at 3-position of pyridine ring and C atom at carboxylic group of stable ${\omega}$-pyridylalkenoic acids. The conformations of ${\omega}$-pyridylalkenoic acids and heme part complex were determined by same method. In theses structures, benzene ring and ethylene group in ${\omega}$-pyridylalkenoic acids are making the structure more rigid and increase inhbitory activity. The electron donating groups in C atom shich is connected to pyridine ring also increase activity.

• Publications of The Korean Astronomical Society
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• v.5 no.1
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• pp.95-103
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• 1990

일반인에게 널리 보급된 IBM 계열의 16비트 PC(XT, AT)로도 손쉽게 도형출력이 가능한 천문 계산용 포트란 그래픽 라이브러리를 CALCOMP계의 문법에 맞추어 개발하였다. 본 라이브러리를 사용하면 그래픽 어댑터(HGC, CGA, EGA, VGA)에 임의로 대응되는 화면출력과 XY플롯터는 물론이거니와 EPSON계의 9핀 혹은 24핀 도트프린터에 의한 고품질(9핀 프린터; 0.21mm/dot, 24핀 프린터; 0.14mm/dot)의 도형출력이 가능하다. 프린터에 의해 출력 가능한 도형의 크기는 하드디스크의 용량이 허용하고 처리 속도를 인내할 수 있는 한 무한대로 확장할 수 있는데 비교적 빠른 시간 내에 처리할 수 있는 표준 도형 크기로서 최대 작도 범위를 80 컬럼용 프린터 용지 한 페이지 크기인 $25cm{\times}20cm$를 지정하였다.