• Title/Summary/Keyword: EE LIM

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Catechin-7-O-$\beta$-D-apiofuranoside: An Anti-inflammatory constituent from alnus japonica bark

  • Jeong, Choon-Sik;Kang, Min-Hee;Hyun, Jin-Ee;Lim, Duk-Yun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.191.3-192
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    • 2003
  • Alnus japonica (Betulaceae) has been traditionally used for purifying blood, and curing feces containing blood, enteritis, diarrhea, alcoholism and cut wounds. In the current work, activity guided isolation of the butanol fraction of the Alnus japonica bark led to the isolation of catechin-7-O-${\beta}$-D-apiofuranoside. Anti-inflammatory activity was determined with carrageenan-induced paw edema in mice as an acute inflammation, complete Freund's adjuvant-induced arthritis as a chronic inflammation. Carrageenan- induced paw edema in mice was significantly inhibited at 0.5, 1, 2, and 3 hr after carrageenan injection by administration of the flavonoid glycoside at the dose of 150mg/kg. (omitted)

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Neural Network-Based Intra Prediction Considering Multiple Transform Selection in Versatile Video Coding (VVC 의 다중 변환 선택을 고려한 신경망 기반 화면내 예측)

  • Dohyeon Park;Gihwa Moon;Sung-Chang Lim;Jae-Gon Kim
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2022.11a
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    • pp.8-9
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    • 2022
  • 최근 VVC(Versatile Video Coding) 표준 완료 이후 JVET(Joint Video Experts Team)에서는 NNVC(Neural Network-based Video Coding) EE(Exploration Experiment)를 통하여 화면내 예측을 포함한 신경망 기반의 부호화 기술들을 탐색하고 검증하고 있다. 본 논문에서는 VVC 에 채택되어 있는 다중 변환 선택(MTS: Multiple Transform Selection)에 따라서 적절한 예측 블록을 선택할 수 있는 TDIP(Transform-Dependent Intra Prediction) 모델을 제안한다. 실험결과 제안기법은 VVC 의 AI(All Intra) 부호화 환경에서 VTM(VVC Test Model) 대비 Y, U, V 에 각각 0.87%, 0.87%, 0.99%의 BD-rate 절감의 비디오 부호화 성능 향상을 보였다.

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Intercellular Adhesion Molecule-1 Gene Polymorphism (K469E) in Korean Preeclamptic Women

  • Lim, Ji-Hyae;Park, So-Yeon;Kim, Shin-Young;Lee, Moon-Hee;Yang, Jae-Hyug;Kim, Moon-Young;Park, Hyun-Young;Lee, Kwang-Soo;Kim, Young-Ju;Ryu, Hyun-Mee
    • Journal of Genetic Medicine
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    • v.5 no.2
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    • pp.105-110
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    • 2008
  • Purpose: Preecalmpsia is a pregnancy-specific disorder that reflects widespread endothelial dysfunction resulting from increases of adhesion molecule expression. Intercellular adhesion molecule-1 (ICAM-1) is involved in the pathogenetic mechanisms responsible for preeclampsia, and ICAM-1 plasma levels and/or function is genetically influenced. Therefore, we evaluated the distribution of ICAM-1 gene K469E polymorphism in pregnant Korean women with preeclampsia and evaluated the association between this polymorphism and preeclampsia. Methods: The K469E polymorphism was analyzed in peripheral blood samples from 197 preeclamptic pregnancies and 193 normotensive pregnancies by a SNapShot kit and an ABI Prism 3100 Genetic analyzer. Results: Genotypic and allelic frequencies of ICAM-1 gene polymorphism (K469E) did not differ between preeclamptic and normotensive pregnancies. The distributions of the KK, KE, and EE genotypes were 40.6%, 43.7%, and 15.7%, respectively, in preeclamptic pregnancies and 38.9%, 45.1%, and 16.1%, respectively, in normotensive pregnancies. The frequencies of K and E alleles were 0.62 and 0.38, respectively, in preeclamptic pregnancies and 0.61 and 0.39, respectively, in normotensive pregnancies. By multiple logistic regression analysis, there was no increased risk of preeclampsia in subjects with ICAM-1 KE (OR, 1.08; P=0.74) or EE (OR, 1.07; P=0.88) genotypes. Conclusion: This study suggests that the ICAM-1 gene K469E polymorphism does not associate with an increased risk of preeclampsia in pregnant Korean women.

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Lignan Glycosides of Vaccinium oldhami Miquel (정금나무의 Lignan Glycoside 성분)

  • Kim, Seong-Jin;Lee, Jeong-Joo;Lee, Sa-Im;Park, Hee-Wook;Lee, Jae-Hyeok;Park, Jeong-Suk;Kim, Sung-Hoon;Baek, Nam-In;Kwon, Young-Ee;Yang, Jae-Heon;Chae, Byeong-Suk;Lim, Jong-Pil;Shin, Tae-Yong;Jeon, Hoon;Eun, Jae-Soon;Kim, Dae-Keun
    • Korean Journal of Pharmacognosy
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    • v.38 no.3 s.150
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    • pp.296-298
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    • 2007
  • Two lignan glycoside compounds were isolated from the twigs of Vaccinium oldhami (Ericaceae) through repeated column chromatography. Their chemical structures were elucidated as lyoniside and ssioriside, respectively, by spectroscopic analysis.

Overemployment of Workers in Penang, Malaysia: An Empirical Analysis

  • Fernandez, Jacqueline Liza;Shiang, Lim Ee
    • The Journal of Asian Finance, Economics and Business
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    • v.4 no.4
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    • pp.17-26
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    • 2017
  • Many workers today encounter the problem of overemployment which occurs when actual working hours exceed preferred or desired working hours. Overemployed workers desire to work fewer hours although this may entail a concomitant decline in earnings. This research is conducted to examine the likelihood of overemployment among employees in a particular state in Malaysia, that is, Penang. This study uses primary data that was collected in a survey encompassing a total of 525 employees in the state. A logit model is used to analyse the relationship between the likelihood of overemployment and various socio-demographic, household and work-related variables. The factors that are significantly related to overemployment are ethnicity, age, education, number of children in the household, occupation, hours of work and control over work schedule. Based on the findings of this paper, it is suggested that policies such as offering part-time jobs or job-sharing options to older workers, implementing family-friendly policies, adopting decent working time measures and strategies that give workers more control over their work schedule are some possible ways to deal with the issue of overemployment.

Size and Aspect Ratio Effects on the Magnetic Properties of a Spin-Valve Multilayer by Computer Simulation

  • Lim, S.H.;Han, S.H.;Shin, K.H.;Kim, H.J.
    • Journal of Magnetics
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    • v.5 no.3
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    • pp.90-98
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    • 2000
  • The change in the magnetic properties of a spin-valve multilayer with the structure IrMn (9 m)/CoFe (4 nm)/Cu (2.6 nm)/CoFe (2 nm)/NiEe (6 nm) is investigated as a function of the size and the aspect ratio. At a fixed aspect ratio (the length/width ratio) of 2, the magnetostatic interactions begin to affect the magnetic properties substantially at a spin-valve length of 5 $\mum$, and, at a length of 1 $\mum$, they become even more dominant. In the case of a fixed multilayer size (2.4 $\mum$) which is indicated by the sum of the length and the width, magnetization change occurs by continuous spin-reversal and M-H loops are characterized by no or very small hysteresis at aspect ratios smaller than unity, At aspect ratios greater than unity, magnetization change occurs by spin-flip resulting in squared hysteresis loops. A very large changes in the coercivity and the bias field is observed, and these results are explained by two separate contributions to the total magnetostatic interactions: the coercivity by the self-demagnetizing field and the bias field by the interlayer magnetostatic interaction field.

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Effects of auricular acupuncture on cholecytokinin in cerebral cortex of sprague dawley rats (이침(耳鍼)이 절식(絶食)시킨 흰쥐의 대뇌피질(大腦皮質)에서 CCK 활성변화(活性變化)에 미치는 영향(影響))

  • Kim, Ee-Hwa;Kim, Youn-Jung;Lim, Baek-Vin;Jang, Mi-Hyun;Chung, Joo-Ho;Kim, Chang-Ju
    • Journal of Acupuncture Research
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    • v.17 no.3
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    • pp.168-175
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    • 2000
  • Stimulation of the auricle is known to be effective in reducing obesity. The aim of the present study is to investigate whether stimulating a specific auricular acupuncture point is effective on suppression of appetite. Cholesystokinin (CCK) is known to induce a powerful feeding response after central administration and particularly abundant in the cerebral cortex. In food-deprived rats exhibiting a strong drive for feeding, decreased CCK release was markedly detected in the cerebral cortex of the brain. Needling the fasted rats on the specific auricular region increased the CCK level of the cerebral cortex. In conclusion, stimulating the specific auricular points increases CCK-expression in the cerebral cortex of the fasted rats and may be useful for controlling obesity.

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Effects of Distraction by a Cellular Phone on Pain and Fear During Venipuncture Procedure for Hospitalized Preschool Children (휴대폰을 이용한 관심전환이 학령전기 입원 아동의 정맥주사시 통증과 두려움에 미치는 효과)

  • Lim, Jung-Hee;Shin, Yeong-Ee
    • Child Health Nursing Research
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    • v.13 no.4
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    • pp.506-511
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    • 2007
  • Purpose: The purpose of this study was to investigate effect of distraction by use of a cellular phone on pain and fear during venipuncture procedure for hospitalized preschool children. Method: Fifty four preschool children aged 3-6 were recruited from one university affiliated hospital in Daegu. Participants were assigned to the control(n=27) to receive usual care or intervention group(n=27) to receive distraction plus usual care. For the assessment of children's pain, FACE scale and mothers' perceptions of their own children's pain, visual analogue scale(VAS) were used. For the assessment of fear, Procedure Behavioral checklist developed by Lebaron and Zeltzer was used. Results: Results showed that intervention group demonstrated significantly less pain scores on FACE(t=2.19, p<.03) as rated by children and on VAS(t=2.78, p<.01) as rated by their mothers. Intervention group showed also significantly less fear scores(t=2.30, p<.02) as rated by the researcher. Conclusion: Distraction with cell phone for relieving pain and fear during venipuncture procedure was effective for the hospitalized preschool children.

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The Anti-allergic Effect of Vinegar Treated Small Black Soybean (Glycine max Merr.) is Mediated Through Inhibition of Histamine Release and Inflammatory Cytokine Secretion

  • Shin, Tae-Yong;Shin, Hye-Young;Lim, Jong-Pil;Jeon, Hoon;Kim, Dae-Keun;Chae, Byeong-Suk;Kwon, Young-Ee;Kang, Sin-Myoung;Chang, Ik-Jun;Park, Jeong-Suk;Lee, Jae-Hyeok
    • Natural Product Sciences
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    • v.13 no.4
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    • pp.337-341
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    • 2007
  • In this report, we investigated the effect of aqueous extract of vinegar treated small black soybean (Glycine max Merr.) (Leguminosae) (VSBS) on mast cell-mediated allergic reaction and pro-inflammatory cytokine secretion. VSBS inhibited compound 48/80-induced systemic reactions. VSBS attenuated immunoglobulin (Ig) E-mediated passive cutaneous anaphylaxis. In addition, VSBS decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated secretion of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6 and interleukin (IL)-8 in human mast cells. Our findings provide evidence that VSBS inhibits mast cell-derived allergic reactions.

Puerariae radix increases Alcohol-induced Suppressed Cell Proliferation and Expression of Nitric Oxide Synthase in Dentate Gyrus of Rats

  • Jang Mi Hyean;Lee Taeck Hyun;Shin Min Chul;Lim Baek Vin;Kim Hyun Bae;Lim Sabina;Kim Jin Woo;Lee Cheong Yeal;Kim Ee Hwa;Kim Chang Ju
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.1
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    • pp.192-196
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    • 2002
  • Traditionally, aqueous extracts of Puerariae radix had been used for the treatment of alcohol-related problems. In the present study, the effect of Puerariae radix on cell proliferation and expression of nitric oxide synthase (NOS) in the dentate gyrus of alcohol-intoxicated rats were investigated via 5-bromo-2' -deoxyuridine (BrdU) immunohistochemistry and nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) histochemistry, respectively. Sprague-Dawley rats weighing 150 ± 10 g were divided into four groups: the control group, the Puerarias radix-treated group, the alcohol-treated group, and the alcohol- and Puerariae radix-treated group. The numbers of both BrdU-positive and NADPH-d-positive cells in the dentate gyrus were inhibited significantly by alcohol administration, while Puerariae radix treatment was shown to increase those numbers. In this study, it was revealed that Puerariae radix possesses protective effect against alcohol-induced suppressed new cell formation and NOS expression in the dentate gyrus. Based on the results, it is possible that NO, which might play an important role in the regulation of cell proliferation, is a major target of the toxic effects of alcohol.