• Title/Summary/Keyword: E3 Dynamics

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Hydrophobic Membrans of Tetrafluoroethylene and 2,2,4, Trifluoro 5 Trifluorometoxy 1,3 Dioxole

  • Gordano, A.;Clarizia, G.;Tocci, E.;Drioli, E.
    • Korean Membrane Journal
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    • v.1 no.1
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    • pp.50-58
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    • 1999
  • Symmetric asymmetric and composite perfluoropolymer membranes made with HYFLON AD have been prepared and evaluated. Porous and non porous symmetric membranes have been prepared by solvent evaporation with various processing conditions. Non-contact atomic force microscopy (AFM) was used to investigate the membrane morphology in air. Analysis of the images gave quantitative imformation on the surface pore strcture in particular on the pore size distributin. Possible useful uses of porous membranes are envisaged in the field of gas-liquid separations such as membrane contactors (MSc) Molecular Dynamics(MD) simulations structure of HYFLON AD 60X copolymer supporting these results are also reported. Amorphous perfluoropolymer membranes appears to be ideal other than in MCs when separation processes have to be performed in hostile environments i.e. high temperatures and aggressive non-aqueous media such as chemicals and solvents. In these cases HYFLON AD mem-branes can exploit the outstanding resistance of perfluoropolymers.

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MiT Family Transcriptional Factors in Immune Cell Functions

  • Kim, Seongryong;Song, Hyun-Sup;Yu, Jihyun;Kim, You-Me
    • Molecules and Cells
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    • v.44 no.5
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    • pp.342-355
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    • 2021
  • The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. In mammals, the MiT family consists of MITF (microphthalmia-associated transcription factor or melanocyte-inducing transcription factor), TFEB (transcription factor EB), TFE3 (transcription factor E3), and TFEC (transcription factor EC). These transcriptional factors belong to the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family and bind the E-box DNA motifs in the promoter regions of target genes to enhance transcription. The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. In addition, they modulate cellular metabolism, mitochondria dynamics, and various stress responses. The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. In different immune cell types, each MiT family member is shown to play distinct or redundant roles and we expect that there is far more to learn about their functions and regulatory mechanisms in host defense and inflammatory responses.

Molecular characteristics of ESBL-producing Escherichia coli isolated from chickens with colibacillosis

  • Yoon, Sunghyun;Lee, Young Ju
    • Journal of Veterinary Science
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    • v.23 no.3
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    • pp.37.1-37.8
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    • 2022
  • Background: Avian pathogenic Escherichia coli (APEC) causes colibacillosis, resulting in significant economic losses in the poultry industry. Objectives: In this study, the molecular characteristics of two extended-spectrum beta-lactamase (ESBL)-producing APEC isolates were compared with previously reported ESBL-producing E. coli isolates. Methods: The molecular characteristics of E. coli isolates and the genetic environments of the ESBL genes were investigated using whole genome sequencing. Results: The two ESBL-producing APEC were classified into the phylogenetic groups C and B1 and ST410 and ST162, respectively. Moreover, the ESBL genes of the two isolates were harbored in different Inc plasmids. The EC1809182 strain, harboring the blaCTX-M-55 gene on the plasmid, exhibited extensive homology to IncFIB (98.4%) and IncFIC(FII) (95.8%). The EC1809191 strain, harboring the blaCTX-M-1 gene, was homologous to IncI1-I (Gamma) (99.3%). All chromosomes carried the multidrug transporter, mdf(A) gene. Mobile genetic elements, adjacent to CTX-M genes, facilitated the dissemination of genes in the two isolates, analogous to other ESBL-producing E. coli isolates. Conclusions: This study clarifies the transmission dynamics of CTX-M genes and supports strengthened surveillance to prevent the transmission of the antimicrobial-resistant genes to humans via the food chain.

A 3-Step Speed Control for Minimizing Energy Consumption for Battery-Powered Wheeled Mobile Robots (배터리로 구동되는 이동 로봇의 에너지 소모 최소화를 위한 3-구간 속도 제어)

  • Kim Byung-Kook;Kim Chong-Hui
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.3
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    • pp.208-220
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    • 2006
  • Energy of wheeled mobile robot is usually supplied by batteries. In order to extend operation time of mobile robots, it is necessary to minimize the energy consumption. The energy is dissipated mostly in the motors, which strongly depends on the velocity profile. This paper investigates various 3-step (acceleration - cruise - deceleration) speed control methods to minimize a new energy object function which considers the practical energy consumption dissipated in motors related to motor control input, velocity profile, and motor dynamics. We performed an analysis on the energy consumption various velocity profile patterns generated by standard control input such as step input, ramp input, parabolic input, and exponential input. Based on these standard control inputs, we analyzed the six 3-step velocity profile patterns: E-C-E, P-C-P, R-C-R, S-C-S, R-C-S, and S-C-R (S means a step control input, R means a ramp control input, P means a parabolic control input, and E means an exponential control input, C means a constant cruise velocity), and suggested an efficient iterative search algorithm with binary search which can find the numerical solution quickly. We performed various computer simulations to show the performance of the energy-optimal 3-step speed control in comparison with a conventional 3-step speed control with a reasonable constant acceleration as a benchmark. Simulation results show that the E-C-E is the most energy efficient 3-step velocity profile pattern, which enables wheeled mobile robot to extend working time up to 50%.

Identification of joint dynamics of mechanical structures using condensed F.E.M. model and experimental modal analysis (축약된 유한요소 모델과 실험적 모우드 해석을 이용한 기계구조물의 연결부 동특성 규명)

  • 최병욱;박병호;김광준
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.3
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    • pp.426-439
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    • 1988
  • Dynamic properties such as stiffness and damping of mechanical joints are essential for the accurate prediction of the dynamic behaviors of the system and subsequent improvement of the design. So far several techniques, analytical, experimental, or both have been developed. A technique using condensed F.E.M. model and Experimental Modal Analysis is presented to identify the joint structural parameters. First, modal parameters of structure are measured by certain complex frequency obtained from experiment to match with the order of the Experimental Modal Analysis model. Finally by equating the modal parameters obtained from experiment with those of the condensed system, the unknown joint structural parameters can be identified. A simulation study is conducted to investigate the accuracy of technique. The experiments are performed with ball bearings in a rotor bearing system.

Dual Effect of Price in E-Commerce Environment: Focusing on Trust and Distrust Building Processes

  • Lee, Jung
    • Asia pacific journal of information systems
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    • v.24 no.3
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    • pp.393-415
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    • 2014
  • This study examines the dynamics of trust and distrust at different price levels. We first note that trust and distrust are built with cognitive and affective foundations, and price is viewed as a financial burden or product quality information. Then, we relate price changes to trust and distrust, and hypothesize their interactions: price as a quality cue will positively moderate the cognitive dimension of trust, whereas price as financial burden will negatively moderate the affective dimensions of trust and distrust. We surveyed 263 online mall shoppers in Korea. Among our eight hypotheses, six are fully supported and two are partially supported. The result shows that price perception interacts with both the cognitive and affective dimensions of trust and distrust, but its specific impacts are distinguished by the price perceptions, whether it is financial burden or product quality information.

Lateral Stability Control for Rear Wheel Drive Vehicles Using Electronic Limited Slip Differential (전자식 차동 제한장치를 이용한 후륜구동 차량의 횡방향 안정성 제어)

  • Cha, Hyunsoo;Yi, Kyongsu
    • Journal of Auto-vehicle Safety Association
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    • v.13 no.3
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    • pp.6-12
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    • 2021
  • This paper presents a lateral stability control for rear wheel drive (RWD) vehicles using electronic limited slip differentials (eLSD). The proposed eLSD controller is designed to increase the understeer characteristic by transferring torque from the outside to inside wheel. The proposed algorithm is devised to improve the lateral responses at the steady state and transient cornering. In the steady state response, the proposed algorithm can extend the region of linear cornering response and can increase the maximum limit of available lateral acceleration. In the transient response, the proposed controller can reduce the yaw rate overshoot by increasing the understeer characteristic. The proposed algorithm has been investigated via computer simulations. In the simulation results, the performance of the proposed controller is compared with uncontrolled cases. The simulation results show that the proposed algorithm can improve the vehicle lateral stability and handling performance.

Filtering Techniques for Chaotic Signals

  • Lee, Chung-Yong
    • The Journal of the Acoustical Society of Korea
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    • v.15 no.3E
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    • pp.45-59
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    • 1996
  • Generalized iterative methods for reducing noise in contaminated chaotic signals are proposed. These methods minimize a cost function composed of two parts : one containing information that represents how close enhanced signals are to the observed signal and another composed of constraints that fit the dynamics of the system. The convergence conditions and the error systems of the proposed are investigated. As one aspect of noise reduction, the suppression or cancellation of a chaotic interference signal is discussed.

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Development and Implementation of Brushless DC Motor Controlles Based on Inteligent Control

  • Park, Jin-Hyun;Park, Young-Kiu
    • Journal of Electrical Engineering and information Science
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    • v.2 no.3
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    • pp.61-65
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    • 1997
  • This paper proposes an intelligent controller for brushless DC motor and load with unknown nonlinear dynamics. The proposed intelligent control system consists of a plant identifier and PID controller with varying gains. The identifier is constructed using an Auto Regressive Moving Average (ARMA) model. In order to tune the parameters of the identifier and the gains of the PID controller efficiently, e also propose a modified Evolution Strategy. Experimental results show that the proposed intelligent controller for brushless DC motor has good control performance under unknown disturbance.

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