• Title/Summary/Keyword: E171

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Effects of Eurycoma longifolia Jack on Masculine Copulatory Behaviour in Middle Aged Male Rats - A Comparison Study

  • Ang, Hooi-Hoon;Lee, Kheng-Leng
    • Natural Product Sciences
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    • v.8 no.2
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    • pp.44-47
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    • 2002
  • The effects of Eurycoma longifolia Jack on masculine copulatory behaviour were studied in the middle aged male Sprague-Dawley rats, 9 months old and retired breeders after dosing them with 500 mg/kg twice daily for 10 days prior to test. The test lasted for 30 minutes after a 20 minute adaptation period, was carried out on the 11th day during the dark phase of the light-dark cycle (2000-0700 hours) and in subdued light, using a modified copulation cage but with the presence of a piece of mirror of appropriate size to facilitate observation. Results showed that the mean values of EL-1, EL-2 and EL-3 of the control middle aged male rats were 103.20 sec, 91.21 sec and 80.00 sec but were significantly (p<0.05) increased to 118.40-120.20 sec, 101.24-171.28 sec and 100.42-110.21 sec respectively in the methanol-chloroform, methanol-butanol-water and methanol-butanol treated middle aged male rats. However, further results also showed that PEI-1 and PEI-2 of the control middle aged male rats were 182.30 sec and 257.2 sec but were significantly (p<0.05) decreased to 100.42-121.31 sec and 40.21-132.31 sec respectively in the methanol-chloroform-butanol-water and methanol-butanol treated middle aged male rats. In conclusion, this study showed that although E. longifolia Jack continued to enhance the sexual activity of the middle aged male rats by extending the duration of coitus and decreasing the refractory period between the different series of copulation, but to a smaller degree as compared to sexually active, adult male rats (Ang and Sim, 1997).

Fishing investigation of trawl fisheries in sea mount of central northern Pacific (북태평양 중부 해산어장에 있어서 저층 트롤의 어획실태)

  • Kim, Young-Seuing;On, Taeg-Yun;Cho, Sam-Kwang;Choi, Seuk-Kwan;Kon, Jeong-Lag;Yang, Won-Seuk
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.41 no.3
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    • pp.179-187
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    • 2005
  • This study was conducted in order to the experiment of bottom trawl fisheries in the sea mount of central northern pacific($30^{\circ}-40^{\circ}N$, $170^{\circ}-175^{\circ}E$), during the period of July 1 to August 25, 2004 by commercial trawl ship. Fishing experiment was carried out by bottom trawl, with the codend of 110mm mesh size. The number of 101 test fishing was done in the sea mount of central northern pacific during 56 days and the total catches were 198,593kg as 18 fish species, and CPUE/day and catches/day were 8.3 hours towing time and 3,546kg. Catch ratio according to each fishing ground was higher with the order of B, C, and E, and catches for B was 7,171.0kg during the towing time of 13.2 hours. Main target species were Pseudopentaceros richardsoni and Beryx splendens, there was 14.9% of damage ratio for fishing gears on catching the target fishes inhabiting on the rough sea bottom. Catches by water depth was the order of 300m below, 301-350m, 451-500m and 351-400m. It is thought that there was no problem on the mesh size because most of fishes caught from the experimental fishing was 30cm over.

Species Composition and Distribution of Set-net Catches on the Coast of Dapo, Geoje Island (거제도 다포 연안 정치망 어획물의 종조성 및 주요 어종의 분포 특성)

  • Jung, Kyung-Mi;Lee, Dong Jin;Kang, Sukyung;Choi, Kwang Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.47 no.6
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    • pp.997-1005
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    • 2014
  • We analyzed annual and seasonal variations in fish species composition and distribution patterns using both daily catch and quantitative analysis data collected from a set-net fishery over a period of two years (2011-2012) on the coast of Dapo, Geoje Island. Set-net fishing season in this area is from May to November, and the annual yield based on the daily catch data was 171,412 kg in 2011, and 102,611 kg in 2012. In total, there were 46 species (belonging to 36 families and 12 orders) in 2011, and 41 species (belonging to 25 families and 9 orders) in 2012. The dominant species in terms of numbers were Trachurus japonicus, Engraulis japonicus, Clupea pallasii, Scomber japonicus, and Sphyraena pinguis. The range in fork length for T. japonicus and E. japonicus was from 3.2 to 23.9 cm, and from 2.6 to 13.3 cm, respectively. The fork length of recruiting juveniles to the Dapo set-net fishing ground ranged from 4.6 to 7.8 cm (median) for T. japonicus, and from 4.1 to 5.0 cm (median) for E. japonicus. The fact that most of the fish caught from the two species were at immature growth stages implies that the coast of Dapo can act as a nursery area for these migratory species.

Studies on Constituents of Higher Fungi of Korea(XXXIV) -Antitumor Components of Ramaria formosa- (한국산(韓國産) 고등(高等) 균류(菌類)의 성분(成分) 연구(硏究)(제34보) -붉은싸리버섯의 항암(抗癌) 성분(成分)-)

  • Yoo, In-Sook;Woo, Myoung-Sik;Choi, Eung-Chil;Kim, Byong-Kak
    • The Korean Journal of Mycology
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    • v.10 no.4
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    • pp.165-171
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    • 1982
  • To investigate antitumor components of Korean higher fungi, the carpophores of Ramaria formosa $(Fr.)Qu\acute{e}l$. were collected in Gang Won Province and extracted with hot water. The extract was concentrated and precipitated by four volumes of ethanol. The precipitate was centrifugated and purified by dialyzing through Visking tube and a protein-bound polysaccharide fraction was obtained. The fraction was tested for antitumor activity against sarcoma 180 implanted in mice. The tumor inhibition ratio of the fraction was 66% in the dose of 50mg/kg/day for the period of ten days. The tumor in two of the eight mice was completely regressed. The components of the fraction were found to be a polysaccharide and a protein. The chemical analysis of the fraction showed that the polysaccharide moiety consisted of four monosaccharides and that the protein moiety contained fourteen amino acids.

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Development of New Collaborative Key Performance Indicators in Manufacturing Collaboration Based on the SCOR Model (SCOR 모형에 기반한 새로운 제조협업의 협력적 성과지표 개발 및 측정)

  • Jung, Ji-Whan;Jung, Jae-Yoon;Shin, Dong-Min;Kim, Sang-Kuk
    • The Journal of Society for e-Business Studies
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    • v.15 no.1
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    • pp.157-171
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    • 2010
  • To effectively maintain manufacturing collaboration, the development of effective performance measurements for the collaboration is required. Most existing key performance indicators however were developed to measure the performances of internal activities or outsourcing of a company. For that reason, it is necessary to devise new key performance indicators that the partners participating in the collaboration can arrange and compromise with each other to reflect their common goals. In this paper, we propose collaborative Key Performance Indicators(cKPIs), which is used to measure the collaboration work of multiple manufacturing partners on the basis of the Supply Chain Operations Reference(SCOR) model. Also, a modified Sigmoid function is devised as a desirability function to reflect the characteristics of Service Level Agreement(SLA) between two partners. The proposed indicators and the desirability functions can be utilized to perform and maintain the successful collaboration by providing a way to the quantitative measurement.

Cloning, Nucleotide Sequencing, and Characterization of the ptsG Gene Encoding Glucose-Specific Enzyme II of the Phosphotransferase System from Brevibacterium lactofermentum

  • Yoon, Ki-Hong;Lee, Kyu-Nam;Lee, Jung-Kee;Park, Se-Cheol
    • Journal of Microbiology and Biotechnology
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    • v.9 no.5
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    • pp.582-588
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    • 1999
  • A Brevibacterium lactofermentum gene coding for a glucose-specific permease of the phosphoenolpyruvate-dependent phosphotransferase system (PTS) was cloned, by complementing an Escherichia coli mutation affecting a ptsG gene with the B. lactofermentum genomic library, and completely sequenced. The gene was identified as a ptsG, which enables an E. coli transformant to transport non-metabolizable glucose analogue 2-deoxyglucose (2DG). The ptsG gene of B. lactofermentum consists of an open reading frame of 2,025 nucleotides encoding a polypeptide of 674 amino acid residues and a TAA stop codon. The 3' flanking region contains two stem-loop structures which may be involved in transcriptional termination. The deduced amino acid sequence of the B. lactofermentum enzyme $II^{GIe}$ specific to glucose ($EII^{GIe}$) has a high homology with the Corynebacterium glutamicum enzyme $II^{Man}$ specific to glucose and mannose ($EII^{Man}$), and the Brevibacterium ammoniagenes enzyme $II^{GIc}$ specific to glucose ($EII^{GIc}$). The 171-amino-acid C-terminal sequence of the $EII^{Glc}$ is also similar to the Escherichia coli enzyme $IIA^{GIc}$ specific to glucose ($IIA^{GIc}$). It is interesting that the arrangement of the structural domains, IIBCA, of the B. lactofermentum $EII^{GIc}$ protein is identical to that of EIIs specific to sucrose or $\beta$-glucoside. Several in vivo complementation studies indicated that the B. lactofermentum $EII^{Glc}$ protein could replace both $EII^{ Glc}$ and $EIIA^{Glc}$ in an E. coli ptsG mutant or crr mutant, respectively.

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Suggestion of Law for Supporting u-Healthcare's Activation (유비쿼터스 보건의료서비스 활성화지원 법률안의 제안)

  • Cho, Hyong-Won
    • The Korean Society of Law and Medicine
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    • v.10 no.1
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    • pp.171-211
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    • 2009
  • Because Korea has the excellent informational technology, it was expected to be able to improve the accessibility to healthcare and compete with other nations in excellence through u-Healthcare. But we can't complete the excellent u-Healthcare because of the law to be able to use only the tele-counselling between doctor to doctor or doctor to nurse. First of all, we must complete the law to be able to use the improved u-Health containing of telemedicine between doctor to patient. Though other factors, the procurement of safe IT, the credibility to healthcare service provider containing of nutritionist and occupational therapist etc. are prepared for erecting u-Healthcare, we can get the final and decisive u-Health policy only by means of Law for supporting u-Healthcare's Activation. The important sections of Law for supporting u-Healthcare's Activation are as follows. Sec. 4 The Minister for Health, Welfare and Family Affairs and the dean of associated administrative division have to erect the combined plan for u-Healthcare's Activation. Sec. 11 Government and local autonomous entity can support the facility and equipment to be necessitated for using u-Healthcare to improve the medical accessibility of person in the region with poor medicine. Sec. 13 Doctor can support other doctor's medical action through IT and if there are not medical risk, doctor can give medical act directly to the special patients. Sec. 21 If pharmaceuticals is necessitated in u-Healthcare, remote doctor has to send the patient the electronic prescription and the pharmaceutist to receive the electronic prescription has to delivery the pharmaceuticals in accordance with patient's demand.

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A study on the occurrence and resolution of disputes among crowd-funding stake-holders (크라우드펀딩 이해관계자 간의 분쟁발생과 해결방안)

  • Kim, Kee Hong
    • Journal of Arbitration Studies
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    • v.31 no.1
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    • pp.155-171
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    • 2021
  • Recently, the e-business market has become a place of convergence where consumers and suppliers communicate with each other, and a new method of trading of funds has emerged in the process. Crowd-funding is one of the types of money transactions that have emerged in the online space, and its interest and trading volume have been growing rapidly recently. The platform in the online space using crowd-funding method operates in the form of online telecommunication sales, and it is in the form of producing and delivering products based on funds obtained from potential consumers by the operators involved in securing funds. However, if the participating business operators do not deliver the product or deliver the product other than the promoted product and avoid responsibility, the potential demander will not be compensated without mediation by the platform operating entity. In this study, despite the rapid growth in the market size of crowd-funding, consumers who participated in the funding are protected and able to resolve disputes in the event of a conflict amid growing complaints from potential consumers and side effects. The structure or method of crowd-funding is a new form of trading that has different features from conventional e-commerce. Therefore, the legal basis is not yet in place and the standards need to be laid out through various and sufficient discussions politically, legally, socially and culturally and economically. As the potential market and positive effects of crowd-funding around the world have been recognized, a role is required as an ecosystem for new financial transactions. And the potential market could be realized as a new industry if the right legal system and policy consultation were made.

Infection Status with Clonorchis sinensis Metacercariae in Fish from Yangcheon (Stream) in Sancheong-gun, Gyeongsangnam-do, Korea

  • Sohn, Woon-Mok;Na, Byoung-Kuk;Cho, Shin-Hyeong;Ju, Jung-Won
    • Parasites, Hosts and Diseases
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    • v.57 no.2
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    • pp.145-152
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    • 2019
  • The infection status with Clonorchis sinensis metacercariae (CsMc) was examined in freshwater fishes from Yangcheon (a branch of Gyeongho-gang), which is located in Sancheong-gun, Gyeongsangnam-do, the Republic of Korea. Total 2,201 fishes in 26 species were examined by the artificial digestion method through 7 years. CsMc were detected in 1,171 (53.2%) fishes in 21 spp. (80.8%) and their density was 85 per fish infected. Total 532 (99.6%) out of 534 Pungtungia herzi (index fish) examined were infected with 147 CsMc per fish infected. Metacercarial densities in this fish were highest in 2015 (179 CsMc), followed by 2012 (168), 2013 (152), 2016 (145), 2014 (114), and 2017 (89) respectively. In the gobioninid fish group, i.e., P. herzi, Sarcocheilichthys spp., Squalidus spp., Pseudogobio esocinus, Hemibarbus longirostris, and Hemibarbus labeo, 841 (92.7%) fishes were infected with 117 CsMc per fish infected. Total 250 (54.7%) acheilognathinid fish (bitterlings), Acheilognathus spp. and Acanthorhodeus spp. were infected with 5.8 CsMc. In the rasborinid fish (chubs) group, i.e., Zacco platypus, Zacco temminckii, and Zacco koreanus, 77 (13.7%) out of 563 fish examined were infected with 2.4 CsMc in average. The susceptibility indices of CsMc were 49.09 in the overall positive fish group, 104.15 in the gobioninid group, 3.17 in the acheilognathinid group and 0.35 in the rasborinid fish group respectively. Only 1 CsMc was detected in 3 fish species, Coreoperca herzi, Channa argus, and Lepomis macrochirus, respectively. Conclusively, it was confirmed that CsMc are moderately prevalent in fishes from Yangcheon in Sancheon-gun, Gyeongsangnam-do, Korea.

Improvement of Calculation Accuracy in the Electron Monte Carlo Algorithm with Optional Air Profile Measurements

  • Sung, Jiwon;Jin, Hyeongmin;Kim, Jeongho;Park, Jong Min;Kim, Jung-in;Choi, Chang Heon;Chun, Minsoo
    • Progress in Medical Physics
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    • v.31 no.4
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    • pp.163-171
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    • 2020
  • Purpose: In this study, the accuracies of electron Monte Carlo (eMC) calculation algorithms were evaluated to determine whether electron beams were modeled by optional air profiles (APs) designed for each applicator size. Methods: Electron beams with the energies of 6, 9, 12, and 16 MeV for VitalBeam (Varian Medical System, Palo Alto, CA, USA) and 6, 9, 12, 16, and 20 MeV for Clinac iX (Varian Medical System) were used. Optional APs were measured at the source-to-detector distance of 95 cm with jaw openings appropriate for each machine, electron beam energy, and applicator size. The measured optional APs were postprocessed and converted into the w2CAD format. Then, the electron beams were modeled and calculated with and without optional APs. Measured profiles, percentage depth doses, penumbras with respect to each machine, and energy were compared to calculated dose distributions. Results: For VitalBeam, the profile differences between the measurement and calculation were reduced by 0.35%, 0.15%, 0.14%, and 0.38% at 6, 9, 12, and 16 MeV, respectively, when the beams were modeled with APs. For Clinac iX, the differences were decreased by 0.16%, -0.31%, 0.94%, 0.42%, and 0.74%, at 6, 9, 12, 16, and 20 MeV, respectively, with the insertion of APs. Of note, no significant improvements in penumbra and percentage depth dose were observed, although the beam models were configured with APs. Conclusions: The accuracy of the eMC calculation can be improved in profiles when electron beams are modeled with optional APs.