• 제목/요약/키워드: E.O.G

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당화된 레스베라트롤의 대식세포 RAW 264.7세포의 생존능력과 레스베라트롤의 면역제어 활성을 증가 (Glucosylation of Resveratrol Improves its Immunomodulating Activity and the Viability of Murine Macrophage RAW 264.7 Cells)

  • 라메스 프라시드 판데이;이지선;박용일;송재경
    • 한국미생물·생명공학회지
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    • 제45권1호
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    • pp.19-26
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    • 2017
  • 레스베라트롤의 면역제어 성질과 대식세포의 생존능력과 관련하여 당화된 레스베라트롤의 효과를 확인하기 위해 대식세포 RAW 264.7에서 연구하였다. 인비토로에서 대식세포에서 총 4개의 레스베라트롤 및 당화된 유도체 (E)-resveratrol, (E)-resveratrol 3-O-${\beta}$-${\small{D}}$-glucoside (R-3-G), 및 (E)-resveratrol 4'-O-${\beta}$-${\small{D}}$-glucoside (R-4'-G)를 여러 가지 농도로 처리한 후 일산화질소 (NO)와 인터루킨 6 (IL-6) 발현을 연구하였다. 앞서 언급한 물질로 처리한 후 인비토로에서 RAW 264.7 세포의 생존능력도 연구하였다. 대식세포 생존능력 평가분석 결과를 보면, 두 개의 레스베라트롤 모노글루코사이드인 R-3-G와 R-4'-G은 (E)-resveratrol와 비교하여 A549 and HepG2 세포에서 50-80% 감소된 독성을 보여준다. 당이 없는 레스베라트롤과 비교하면, 당화된 레스베라트 유도체는 긍정적으로 전사적으로 IL-6 및 iNOS 발현이 높아지는 방향으로 NO 및 대식세포에서 IL-6의 생산이 조절된다. 레스베라트롤의 당의 역할은 RAW 264.7 세포의 생존능력과 레스베라트롤의 면역제어 활성을 증가시켜 주는 것으로 보여주고 있다.

GROUP S3 CORDIAL REMAINDER LABELING FOR PATH AND CYCLE RELATED GRAPHS

  • LOURDUSAMY, A.;WENCY, S. JENIFER;PATRICK, F.
    • Journal of applied mathematics & informatics
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    • 제39권1_2호
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    • pp.223-237
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    • 2021
  • Let G = (V (G), E(G)) be a graph and let g : V (G) → S3 be a function. For each edge xy assign the label r where r is the remainder when o(g(x)) is divided by o(g(y)) or o(g(y)) is divided by o(g(x)) according as o(g(x)) ≥ o(g(y)) or o(g(y)) ≥ o(g(x)). The function g is called a group S3 cordial remainder labeling of G if |vg(i)-vg(j)| ≤ 1 and |eg(1)-eg(0)| ≤ 1, where vg(j) denotes the number of vertices labeled with j and eg(i) denotes the number of edges labeled with i (i = 0, 1). A graph G which admits a group S3 cordial remainder labeling is called a group S3 cordial remainder graph. In this paper, we prove that square of the path, duplication of a vertex by a new edge in path and cycle graphs, duplication of an edge by a new vertex in path and cycle graphs and total graph of cycle and path graphs admit a group S3 cordial remainder labeling.

O-RAN 공인시험 프로세스와 종단간 시험 기술 분석 (O-RAN Certification/Badging Process and End-to-End Test Case Analysis )

  • 김정환;남기동
    • 전자통신동향분석
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    • 제39권1호
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    • pp.14-24
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    • 2024
  • The O-RAN Alliance is responsible for defining the technical and testing specifications of open radio access networks, aiming for openness, virtualization, and intelligence in these networks. Recently, the application of Korea Open Testing and Integration Center (OTIC) to this alliance has been approved, enabling the issuance of O-RAN certificates and badges. An OTIC plays a crucial role as a testing facility in performing conformance verification and interoperability tests for O-RAN functions and interfaces. In addition, it enables end-to-end system verification adhering to O-RAN principles and processes. These activities can substantially contribute to enhancing the competitiveness of domestic O-RAN products and activating the corresponding ecosystem. We comprehensively describe the O-RAN certification and badging processes. Additionally, we analyze end-to-end test cases that are essential for the proper deployment and operation of 5G systems including O-RANs.

Bi12(Si,Ge)O20 단결정의 전기 및 광학적 특성 (Electrical and Optical Properties of Bi12(Si,Ge)O20 Single Crystals)

  • 김덕훈;문정학;이찬구;이수대
    • 한국안광학회지
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    • 제1권2호
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    • pp.37-42
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    • 1996
  • $Bi_{12}(Si,Ge)O_{20}$ 단결정의 전기 및 광학적 특성을 규명하기 위하여 Czochralski법으로 단결정을 성장시켜, 직류전기전도도와 교류전기전도도 그리고 광투과도를 측정하였다. 직류전기전도도에 대한 활성화 에너지 $E_g$는 1.12 eV 이고, 광학적 갭 $E_{opt}$는 2.3 eV였다. $Bi_{12}(Si,Ge)O_{20}$ 단결정의 교류전기전도도는 측정온도 범위는 290 K에서 570 K까지 였으며 측정주파수는 50 kHz에서 30 MHz 까지 였다. 교류전기전도도는 ${\omega}^s$에 비례하는 hopping 전도 가구를 나타내었으며, 고주파수영역에서 지수값은 s=2로 구해졌다. 유전상수는 $Bi_{12}(Si,Ge)O_{20}$ 단결정의 경우 54이고 $Bi_{12}(Si,Ge)O_{20}$ 단결정의 경우 41정도의 크기를 보였다.

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E.O.G.를 이용한 Corrective Saccadic 안구운동 특성 (Characteristics of Corrective Saccadic Eye Movement with E.O.G.)

  • 김윤수;박상희
    • 대한의용생체공학회:의공학회지
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    • 제2권1호
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    • pp.21-30
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    • 1981
  • In this study, measuring eye movements with E.O.G. to targets beyond 20$^{\circ}$ from fixation point, results are as follows. (1) When the eyes turn toward targets of more than 20$^{\circ}$ eccentricity, the first saccadic eye movement falls short of the target. The presence of image of the target off the fovea(visual error signal) subsequent to such an undershoot elicits, after short interval, corrective saccadic eye movements(usually one) which place the image of the target on the fovea. (2) There are different programming modes at retina for eye movement to targets within and beyond 20$^{\circ}$ from the fixation point. (3) Saccadic system, preparing the direction and amplitude of eye movement completes the corrective saccadic eye movements. (4) Distribution of latency and intersaccadic interval(I.S.I.)are frequently multi modal, with a seperation between modes of 25[msec]. (5) There are two types of saccadic eye movements for the double-step targets. This fact suggests that the visual information is sampled stochastically. (6) The new model of saccadic system including the dissociation of visual functions dependent on retinal eccentricity is required.

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Υ-선 및 훈증제 처리가 당근분말의 품질에 미치는 영향 (Comparative Effects of Υ-irradiation and Ethylene Oxide Fumigation on the Quality of Carrot Powder)

  • 권중호;변명우
    • 한국식품저장유통학회지
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    • 제1권1호
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    • pp.21-27
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    • 1994
  • For the purpose of improving microbiolgical quality of carrot powder, which is being used as minor ingredients of convenience foods, comparative influence of Υ-irradiation and ethylene oxide(E.O) fumigation was investigated with emphasis on sterilizating effect and physicochemical propertied Carrot powder sample was contaminated with thermophiles 4.0$\times$103/g, acid tolerant bacteria 3.7$\times$103/g and coliforms 1.6$\times$102/g, respectively. And thus sanitation process was required. E.O fumigation in commercial practice was not enough to destroy thermophilic bacteria, while Υ-irradiation at below 5 kGy could reduce all microorganisms up to undectected levels. Radiosensitivity(D10) of thermophiles was shown to be 2.25 kGy. The applicable dose of irradiation to the improvement of microbiological quality showed insignificant influences on the physicochemical quality of the sample.

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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

  • Nugroho, Agung;Choi, Jae Sue;Seong, Su Hui;Song, Byong-Min;Park, Kyoung-Sik;Park, Hee-Juhn
    • Natural Product Sciences
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    • 제24권4호
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    • pp.259-265
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    • 2018
  • The three flavone glycosides, 4'-O-methylisoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (1), isoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (3), and isoscutellarein 7-O-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-${\beta}$-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae). In cholinesterase inhibition assay, compound 1 significantly inhibited aceylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities ($IC_{50}s$, $39.94{\mu}g/ml$ for AChE and $86.98{\mu}g/ml$ for BChE). The content of isolated compounds were evaluated in this plant extract by HPLC analysis. Our experimental results suggest that the flavonoid glycosides of S. japonica could prevent the memory impairment of Alzheimer's disease.

Antibody Layer Fabrication for Protein Chip to Detect E. coli O157:H7, Using Microcontact Printing Technique

  • KIM HUN-SOO;BAE YOUNG-MIN;KIM YOUNG-KEE;OH BYUNG-KEUN;CHOI JEONG-WOO
    • Journal of Microbiology and Biotechnology
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    • 제16권1호
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    • pp.141-144
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    • 2006
  • An antibody layer was fabricated to detect Escherichia coli O157:H7. The micropattern of 16-mercaptohexadecanoic acid (16-MHDA) as alkylthiolate was formed on the gold surface by using the PDMS stamp with microcontact printing $({\mu}CP)$ techniques. In order to form antibody patterns on the template, protein G was chemically bound to the 16-MHDA patterns, and antibody was adsorbed on a self-assembled protein G layer. The formation of the 16-MHDA micropattern, self-assembled protein G layer and antibody pattern on Au substrate was confirmed by surface plasmon resonance (SPR) spectroscopy. Finally, the micropatterning method was applied to fabricate the antibody probe for detection of E. coli O157:H7, and monitoring of antigen by using this probe was successfully achieved.

GROUP ACTIONS IN A UNIT-REGULAR RING WITH COMMUTING IDEMPOTENTS

  • Han, Jun-Cheol
    • East Asian mathematical journal
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    • 제25권4호
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    • pp.433-440
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    • 2009
  • Let R be a ring with unity, X the set of all nonzero, nonunits of R and G the group of all units of R. We will consider some group actions on X by G, the left (resp. right) regular action and the conjugate action. In this paper, by investigating these group actions we can have some results as follows: First, if E(R), the set of all nonzero nonunit idempotents of a unit-regular ring R, is commuting, then $o_{\ell}(x)\;=\;o_r(x)$, $o_c(x)\;=\;\{x\}$ for all $x\;{\in}\;X$ where $o_{\ell}(x)$ (resp. $o_r(x)$, $o_c(x)$) is the orbit of x under the left regular (resp. right regular, conjugate) action on X by G and R is abelian regular. Secondly, if R is a unit-regular ring with unity 1 such that G is a cyclic group and $2\;=\;1\;+\;1\;{\in}\;G$, then G is a finite group. Finally, if R is an abelian regular ring such that G is an abelian group, then R is a commutative ring.

Mn-dimer 분자자성체의 전자구조 및 자기구조 계산 (Electronic and Magnetic Structure Calculations of Mn-dimer Molecular Magnet)

  • 박기택
    • 한국자기학회지
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    • 제24권4호
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    • pp.97-100
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    • 2014
  • 분자자성체 Mn-dimer의 전기구조 및 자기적 성질을 제1원리의 범밀도함수법을 이용하여 계산하였다. 계산 된 결과, 전자구조는 벌크 MnO와 비슷한 Mn 주위의 4개의 산소 원자에 의해 $t_{2g}$, $e_g$ 에너지 준위로 분리되어 있었다. 적은 수의 배위원자로 이 결정장 분리는 작았디. 총에너지 계산에서는 반강자성적 상호작용이 낮은 에너지를 가지고 있었다. 계산 된 $Mn^{+2}$ 원자 사이의 교환상호작용 크기는 다른 Mn-O 분자자성체보다 한 단위 큰 값을 얻었다. 이 원인은 Mn 3d 사이의 직접 상호작용과 Mn-O의 강한 결합으로 인한 초교환상호작용의 결과이다.