• Title/Summary/Keyword: E.O.G

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Glucosylation of Resveratrol Improves its Immunomodulating Activity and the Viability of Murine Macrophage RAW 264.7 Cells (당화된 레스베라트롤의 대식세포 RAW 264.7세포의 생존능력과 레스베라트롤의 면역제어 활성을 증가)

  • Pandey, Ramesh Prasad;Lee, Jisun;Park, Yong Il;Sohng, Jae Kyung
    • Microbiology and Biotechnology Letters
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    • v.45 no.1
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    • pp.19-26
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    • 2017
  • Effects of resveratrol glucosylation on the immunomodulation properties of resveratrol and on the viability of macrophage cells have been studied by using murine macrophage RAW 264.7 cells. Nitric oxide (NO) and interleukin 6 (IL-6) expression in macrophages in vitro were studied after treatment with different concentrations of (E)-resveratrol, (E)-resveratrol 3-O-${\beta}$-${\small{D}}$-glucoside (R-3-G), or (E)-resveratrol 4'-O-${\beta}$-${\small{D}}$-glucoside (R-4'-G). In vitro viability of RAW 264.7 cells after treatment with the aforementioned three compounds was also studied. As demonstrated by macrophage cell viability assays, two different resveratrol monoglucosides, R-3-G and R-4'-G, exhibited 50-80% reduced cytotoxicity in comparison to (E)-resveratrol in A549 and HepG2 cells. Compared to the resveratrol aglycon, both glucosylated resveratrol derivatives positively modulated NO and IL-6 production in macrophages positively via transcriptionally up-regulating IL-6 and iNOS expression. Conjugation of a glucose moiety on resveratrol was found to enhance the immunomodulating activity of resveratrol and the viability of RAW 264.7 cells.

GROUP S3 CORDIAL REMAINDER LABELING FOR PATH AND CYCLE RELATED GRAPHS

  • LOURDUSAMY, A.;WENCY, S. JENIFER;PATRICK, F.
    • Journal of applied mathematics & informatics
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    • v.39 no.1_2
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    • pp.223-237
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    • 2021
  • Let G = (V (G), E(G)) be a graph and let g : V (G) → S3 be a function. For each edge xy assign the label r where r is the remainder when o(g(x)) is divided by o(g(y)) or o(g(y)) is divided by o(g(x)) according as o(g(x)) ≥ o(g(y)) or o(g(y)) ≥ o(g(x)). The function g is called a group S3 cordial remainder labeling of G if |vg(i)-vg(j)| ≤ 1 and |eg(1)-eg(0)| ≤ 1, where vg(j) denotes the number of vertices labeled with j and eg(i) denotes the number of edges labeled with i (i = 0, 1). A graph G which admits a group S3 cordial remainder labeling is called a group S3 cordial remainder graph. In this paper, we prove that square of the path, duplication of a vertex by a new edge in path and cycle graphs, duplication of an edge by a new vertex in path and cycle graphs and total graph of cycle and path graphs admit a group S3 cordial remainder labeling.

O-RAN Certification/Badging Process and End-to-End Test Case Analysis (O-RAN 공인시험 프로세스와 종단간 시험 기술 분석)

  • J.H. Kim;G.D. Nam
    • Electronics and Telecommunications Trends
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    • v.39 no.1
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    • pp.14-24
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    • 2024
  • The O-RAN Alliance is responsible for defining the technical and testing specifications of open radio access networks, aiming for openness, virtualization, and intelligence in these networks. Recently, the application of Korea Open Testing and Integration Center (OTIC) to this alliance has been approved, enabling the issuance of O-RAN certificates and badges. An OTIC plays a crucial role as a testing facility in performing conformance verification and interoperability tests for O-RAN functions and interfaces. In addition, it enables end-to-end system verification adhering to O-RAN principles and processes. These activities can substantially contribute to enhancing the competitiveness of domestic O-RAN products and activating the corresponding ecosystem. We comprehensively describe the O-RAN certification and badging processes. Additionally, we analyze end-to-end test cases that are essential for the proper deployment and operation of 5G systems including O-RANs.

Electrical and Optical Properties of Bi12(Si,Ge)O20 Single Crystals (Bi12(Si,Ge)O20 단결정의 전기 및 광학적 특성)

  • Kim, Douk Hoon;Mun, Jung Hak;Lee, Chanku;Lee, Sudae
    • Journal of Korean Ophthalmic Optics Society
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    • v.1 no.2
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    • pp.37-42
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    • 1996
  • The $Bi_{12}(Si,Ge)O_{20}$ single crystals were prepared by Czochralski method and the study of electrical and optical properties were carried out. The activation energy of the electrical conductivity was $E_g$=1.12 eV. The optical energy gap measured in the room temperature is found to be 2.3 eV. A.c. conductivity of crystal $Bi_{12}(Si,Ge)O_{20}$ was measured at temperatures from 290 K to 570 K in the frequency range from 50 kHz to 30 MHz. The a.c. conductivity is proportional to ${\omega}^s$. In view of this it should be hopping conduction mechanisms. At high frequencies, the power exponent was s=2. The low frequency dielectric constants were 54 for $Bi_{12}(Si,Ge)O_{20}$ and 41 for $Bi_{12}(Si,Ge)O_{20}$ single crystals.

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Characteristics of Corrective Saccadic Eye Movement with E.O.G. (E.O.G.를 이용한 Corrective Saccadic 안구운동 특성)

  • 김윤수;박상희
    • Journal of Biomedical Engineering Research
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    • v.2 no.1
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    • pp.21-30
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    • 1981
  • In this study, measuring eye movements with E.O.G. to targets beyond 20$^{\circ}$ from fixation point, results are as follows. (1) When the eyes turn toward targets of more than 20$^{\circ}$ eccentricity, the first saccadic eye movement falls short of the target. The presence of image of the target off the fovea(visual error signal) subsequent to such an undershoot elicits, after short interval, corrective saccadic eye movements(usually one) which place the image of the target on the fovea. (2) There are different programming modes at retina for eye movement to targets within and beyond 20$^{\circ}$ from the fixation point. (3) Saccadic system, preparing the direction and amplitude of eye movement completes the corrective saccadic eye movements. (4) Distribution of latency and intersaccadic interval(I.S.I.)are frequently multi modal, with a seperation between modes of 25[msec]. (5) There are two types of saccadic eye movements for the double-step targets. This fact suggests that the visual information is sampled stochastically. (6) The new model of saccadic system including the dissociation of visual functions dependent on retinal eccentricity is required.

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Comparative Effects of Υ-irradiation and Ethylene Oxide Fumigation on the Quality of Carrot Powder (Υ-선 및 훈증제 처리가 당근분말의 품질에 미치는 영향)

  • 권중호;변명우
    • Food Science and Preservation
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    • v.1 no.1
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    • pp.21-27
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    • 1994
  • For the purpose of improving microbiolgical quality of carrot powder, which is being used as minor ingredients of convenience foods, comparative influence of Υ-irradiation and ethylene oxide(E.O) fumigation was investigated with emphasis on sterilizating effect and physicochemical propertied Carrot powder sample was contaminated with thermophiles 4.0$\times$103/g, acid tolerant bacteria 3.7$\times$103/g and coliforms 1.6$\times$102/g, respectively. And thus sanitation process was required. E.O fumigation in commercial practice was not enough to destroy thermophilic bacteria, while Υ-irradiation at below 5 kGy could reduce all microorganisms up to undectected levels. Radiosensitivity(D10) of thermophiles was shown to be 2.25 kGy. The applicable dose of irradiation to the improvement of microbiological quality showed insignificant influences on the physicochemical quality of the sample.

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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

  • Nugroho, Agung;Choi, Jae Sue;Seong, Su Hui;Song, Byong-Min;Park, Kyoung-Sik;Park, Hee-Juhn
    • Natural Product Sciences
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    • v.24 no.4
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    • pp.259-265
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    • 2018
  • The three flavone glycosides, 4'-O-methylisoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (1), isoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (3), and isoscutellarein 7-O-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-${\beta}$-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae). In cholinesterase inhibition assay, compound 1 significantly inhibited aceylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities ($IC_{50}s$, $39.94{\mu}g/ml$ for AChE and $86.98{\mu}g/ml$ for BChE). The content of isolated compounds were evaluated in this plant extract by HPLC analysis. Our experimental results suggest that the flavonoid glycosides of S. japonica could prevent the memory impairment of Alzheimer's disease.

Antibody Layer Fabrication for Protein Chip to Detect E. coli O157:H7, Using Microcontact Printing Technique

  • KIM HUN-SOO;BAE YOUNG-MIN;KIM YOUNG-KEE;OH BYUNG-KEUN;CHOI JEONG-WOO
    • Journal of Microbiology and Biotechnology
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    • v.16 no.1
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    • pp.141-144
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    • 2006
  • An antibody layer was fabricated to detect Escherichia coli O157:H7. The micropattern of 16-mercaptohexadecanoic acid (16-MHDA) as alkylthiolate was formed on the gold surface by using the PDMS stamp with microcontact printing $({\mu}CP)$ techniques. In order to form antibody patterns on the template, protein G was chemically bound to the 16-MHDA patterns, and antibody was adsorbed on a self-assembled protein G layer. The formation of the 16-MHDA micropattern, self-assembled protein G layer and antibody pattern on Au substrate was confirmed by surface plasmon resonance (SPR) spectroscopy. Finally, the micropatterning method was applied to fabricate the antibody probe for detection of E. coli O157:H7, and monitoring of antigen by using this probe was successfully achieved.

GROUP ACTIONS IN A UNIT-REGULAR RING WITH COMMUTING IDEMPOTENTS

  • Han, Jun-Cheol
    • East Asian mathematical journal
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    • v.25 no.4
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    • pp.433-440
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    • 2009
  • Let R be a ring with unity, X the set of all nonzero, nonunits of R and G the group of all units of R. We will consider some group actions on X by G, the left (resp. right) regular action and the conjugate action. In this paper, by investigating these group actions we can have some results as follows: First, if E(R), the set of all nonzero nonunit idempotents of a unit-regular ring R, is commuting, then $o_{\ell}(x)\;=\;o_r(x)$, $o_c(x)\;=\;\{x\}$ for all $x\;{\in}\;X$ where $o_{\ell}(x)$ (resp. $o_r(x)$, $o_c(x)$) is the orbit of x under the left regular (resp. right regular, conjugate) action on X by G and R is abelian regular. Secondly, if R is a unit-regular ring with unity 1 such that G is a cyclic group and $2\;=\;1\;+\;1\;{\in}\;G$, then G is a finite group. Finally, if R is an abelian regular ring such that G is an abelian group, then R is a commutative ring.

Electronic and Magnetic Structure Calculations of Mn-dimer Molecular Magnet (Mn-dimer 분자자성체의 전자구조 및 자기구조 계산)

  • Park, Key Taeck
    • Journal of the Korean Magnetics Society
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    • v.24 no.4
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    • pp.97-100
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    • 2014
  • We have studied electronic and magnetic structure of Mn-dimer molecule using OpenMX method based on density functional method. The calculated density of states shows that the four O atoms split $e_g$ and $t_{2g}$ energy levels. The energy splitting by the crystal field is smaller than bulk MnO with cubic structure, because of small coordination number of atoms. Total energy with antiferromagnetic spin configuration is lower than that of ferromagnetic configurations. Calculated exchange interaction J between Mn atoms is one order larger than that of the other Mn-O magnetic molecules. That comes from the direct exchange interaction between Mn 3d orbitals and the super-exchange interactions caused by strong ${\sigma}$-bonding of Mn-O orbitals.