• Title/Summary/Keyword: E.D.M.

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Effect of 2,4-Dichlorophenoxy Acetic Acid on Vitellogenin Synthesis and $E_2$-ER Binding Affinity of Hepatocytes in Rainbow Trout (Oncorhynchus mykiss) (무지개송어, Oncorhynchus mykiss 배양 간세포에서 2,4-Dichlorophenoxy acetic acid이 Vitellogenin 합성과 $E_2$-ER Binding Affinity에 미치는 영향)

  • 황운기
    • Journal of Aquaculture
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    • v.15 no.1
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    • pp.31-37
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    • 2002
  • Effect of 2,4-Dichlorophenoxy acetic acid (2,4-D) on vitellogenin (VTG) production and estrogen ($E_2$)-estrogen receptor (ER) binding affinity were examined in primary hepatocyte cultures of rainbow trout, Oncorhynchus mykiss. Hepatocytes were pre-cultured for 2 days; subsequently, $E_2$( 2$\times$$10^{-6}$/ M) and 2,4-D ($10^{-9}~10^{-6}/M$) were simultaneously added to the incubation medium. They were cultured for more than 5 days. VTG and $E_2$-ER binding affinities were analyzed by SDS-PAGE and ELISA, respectively. 2,4-D concentration used had no appreciable effect on the morphology, viability, and DNA content of hepatocytes in culture. It had also no effect on VTG production. However, it interfered with $E_2$-ER binding affinity, which was reduced with increasing concentration of 2,4-D. The affinity was inhibited by 25 and 30% at $10^{-7}$ M and $10^{-6}$ M of 2,4-D, respectively. This result suggested that although 2,4-D had no effect on VTG production, it acted as reno-estrogenic contaminant in ER.

Fatigue fracture characteristics at a electro discharge machined surface in high strength steel (高硬質재료 放電加工部의 피로파괴특성)

  • 김민건;지정근;태원필
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.1
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    • pp.21-26
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    • 1993
  • A study on the fatigue fracture at electro discharge machined(E.D.M) surface has been made with special emphases on the microstructure variation and the residual stress distribution at the E.D.H heat affected zone. Results obtained are summarized as follows. (1) E.D.M brings about a variation of microstructure in heat affected zone, structures of molten, quenching, tempering are formed in order of formation from E.D.M surface. (2) Residual stress generated by E.D.M reduces the fatigue strength of the material through the influencing fatigue crack initiation and growth. (3) Magnitude of the residual stress existed in a microscopic area is approximately estimated by a COD measurement method which was originally suggested by authors.

Comparison of the accuracy of domestic dental intra-oral scanner(e-scanner) and model scanner (국산 치과용 구강스캐너(e-scanner)와 모델스캐너의 정확도 비교)

  • Kim, Busob;Kim, Jungho
    • Journal of Technologic Dentistry
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    • v.41 no.2
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    • pp.53-61
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    • 2019
  • Purpose: The purpose of this study is to evaluate the discrepancy of scan process in dental intra oral scanner by comparing model scanner and anticipate possibility to introduce intra oral scan technique. Methods: 3D superimposition test was conducted to compare the scan discrepancy. The scanners used in this study are the e-oral scanner, the D750 model scanner, and the high precision CMM(3D Coordinate Measuring Machine). The standard of accuracy verification is ISO 5725-1; trueness and precision. Master model was manufactured by dental stone and scanned 5 times by intra oral, model scanner. Reference data was scanned 5 times by high accuracy CMM to evaluate the trueness. Results: Trueness of D750 scanner were $7.4{\mu}m$ $5.1{\mu}m$ $6.8{\mu}m$ at an abutment, an occluasal, a specific area. and trueness of e-scanner were $20.2{\mu}m$ $27.4{\mu}m$ $37.8{\mu}m$ at an abutment, an occluasal, a specific area. Precision of D750 scanner was $7.04{\mu}m$, e-scanner was $15.95{\mu}m$. Conclusion: When conducting in vitro test, The mean difference of trueness between e-scanner and D750 were $12.8{\mu}m$ at an abutment area, $22.3{\mu}m$ at an occlusal area, $31.0{\mu}m$ at a specific area and $8.91{\mu}m$ in precision. The scan discrepancies are within the range of clinical acceptance.

METRIZATION OF THE FUNCTION SPACE M

  • Lee, Joung-Nam;Yang, Young-Kyun
    • Journal of applied mathematics & informatics
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    • v.11 no.1_2
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    • pp.391-399
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    • 2003
  • Let (X,S,$\mu$) be a measure space and M be the vector space of all real valued S-measurable functions defined on (X,S,$\mu$). For $E\;{\in}\;S$ with $\mu(E)\;<\;{\infty}$, $d_E$ is a pseudometric on M. With the notion of D = {$d_E$\mid$E\;{\in}\;S,\mu(E)\;<\;{\infty}$}, in this paper we investigate some topological structure T of M. Indeed, we shall show that it is possible to define a complete invariant metric on M which is compatible with the topology T on M.

Studies on theEfficacy of Machili Cortex in the Digestive System (한국후박(韓國厚朴)(Machili Cortex)의 소화기계(消化器系)에 대한 약효연구(藥效硏究))

  • Lee, Byoung-Joo;Chung, Myung-Hyun
    • Korean Journal of Pharmacognosy
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    • v.25 no.3
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    • pp.278-292
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    • 1994
  • This study was attempted to investigate the effect of Machili Cortex extract(Machilus thunbergii Sieb. et Zucc. ) on digestive system in experimental animals. EtOH and MeOH extracts(E.E. and M.E.) were found to inhibit the charcoal transport rate in the small intestine of mice. E.E. exhibited the inhibition of spontaneous movement(motility) and tension in the ileum and colon strips of rabbit, and these actions were inhibited by action of acetylcholine. E.E. and M.E. given intraduodenaly(i.d.) exhibitied the significant decrease of gastric acid secretion in pylorus-ligated rats. E.E. and M.E. inhibited the formation of some experimental gastric ulcers(pylorus ligation-ulcer i.d., indomethacin-induced ulcer p.o. and aspirin-induced ulcer p.o. ) in rats, which are considered to relate to a protective action. E.E. and M.E. caused remarkable increase of bile excretion, compared with normal-control group, when adminstered through i.d., i.v. and p.o. The antibacterial activity against several intestinal microorganisms and other bacteria in vitro test was observed in the administration of E.E. and M.E.

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A Study on Printed Books of $M\grave{e}ngz\check{i}$ in Choseon Dynasty (조선시대에 간행된 <맹자(孟子)>의 제판본(諸板本)에 관한 연구(硏究))

  • Ahn, Hyeon-Ju
    • Journal of Korean Library and Information Science Society
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    • v.37 no.1
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    • pp.305-328
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    • 2006
  • This paper is a bibliographic analysis on printed books of $M\grave{e}ngz\check{i}$(孟子) in Choseon Dynasty. Through examination of the physical characteristics of books in many institutes and private collections, $M\grave{e}ngz\check{i}j\acute{i}zh\grave{u}d\grave{a}q\acute{a}n$(孟子集註大全)was systematically explored, which was the most frequently published $M\grave{e}ngz\check{i}$(孟子) in Choseon Dynasty. $M\grave{e}ngz\check{i}$(孟子) was published mainly in Kyungki and Kyungsang provinces, and in the period of 17C to 19C. There are two streams of $M\grave{e}ngz\check{i}j\acute{i}zh\grave{u}d\grave{a}q\acute{a}n$. One is the series of the reprinted edition of $M\acute{i}ngbon$(明本覆刻), originated from Saseookyungdaejun(四書五經大全), compiled by Hokwang(湖廣) and colleagues in $M\acute{i}ng$(明). The second is the series of Chungyuja books(丁酉字本) among movable type books of Choseon(朝鮮活字本), the contents of which being the same as the other stream. Also, $M\grave{e}ngz\check{i}d\grave{a}iw\acute{e}n$(孟予大文) and $M\grave{e}ngz\check{i}zh\grave{e}ngw\acute{e}n$(孟子正文) are frequently published.

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Microcomputer Based Vacuum Drying System and its Application to the Vacuum Drying of Green Red Pepper (마이크로컴퓨터 감압건조(減壓乾燥)시스템의 제작운영(製作運營)과 풋고추의 감압건조특성(減壓乾燥特性))

  • Chun, Jae-Kun;Kang, Jun-Soo
    • Applied Biological Chemistry
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    • v.30 no.1
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    • pp.65-70
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    • 1987
  • In Girder to measure the pressure and weight decrease of drying sample during the vacuum drying process of food, sensing devices were designed and constructed with strain gauge. Microcomputer based vacuum drying system was made up of these devices interfaced to apple II microcomputer. The electrical output signal from vacuum sensor which constituted with Bourdon tube whereon strain gauge attached were digitalized and input to microcomputer through the MC 6821 interface I.C. chip. The relationship between read-out digital value (D) from microcomputer and readings of vacuum gauge (P, mmHg) was P=-146.136+3.620D'(r=0.9994) The pressure control of vacuum dryer was successfully conducted in the range of $400{\sim}600\;mmHg$ accuracy. The digitalized load cell output (D) could be correlated with the real weight (W, g) as W=-14,000+0.585D (r=0.9998) Drying curves of green red pepper under $64^{\circ}C$, $400{\sim}600\;mmHg$ was similar to those of red pepper and differently affected by the degree of vacuum pressure but was varied according to their shape (cut or whole). Moisture movement of green red pepper during the vacuum drying process was fitted to Page model. The empirical equations obtained were $M-M_e/M_o-M_e={\exp}\;(-0.0673{\theta}^{1.177})$ and $M-M_e/M_o-M_e={\exp}\;(-0.0655\;{\theta}^{1.477})$ for whole and cut green red pepper, respectively.

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Study on the Manufacturing Properties of Korean-type Koumiss (한국형 Koumiss제조 특성에 관한 연구)

  • Lee, Jong-Ik;Song, Kwang-Young;Chon, Jung-Whan;Hyeon, Ji-Yeon;Seo, Kun-Ho
    • The Korean Journal of Food And Nutrition
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    • v.24 no.3
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    • pp.367-375
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    • 2011
  • For this study, Korean-type Koumiss was made by the fermentation of mixed cultures, in which yeast, Kuyveromyces, and microflora, Streptococcus thermophiles and Lactobacillus bulgaricus, were inoculated into 10% skimmed milk with added whey powder(control: A, 2%: B, 4%: C, 6%: D, and 8%: E). Fat, protein, lactose, titratable acidity, pH, the number of lactic acid bacteria, the number of yeast, alcohol content, volatile fatty acids, volatile free amino acids and minerals were measured in the products. The results were as follows: As the dosage of whey powder increased, fat increased from 0.74% in the control to 2.30% in sample E, protein increased from 2.95% in the control to 4.39% in sample E and lactose increased from 3.10% in the control to 7.43% in sample E. Titratable acidity and pH increased gradually. The number of lactic acid bacteria increased from $10^9\;cfu/m{\ell}$ in the control to $3.8{\times}10^9\;cfu/m{\ell}$ in sample E, and the number of yeast increased from $6.1{\times}10^7\;cfu/m{\ell}$ in the control to $1.65{\times}10^8\;cfu/m{\ell}$ in sample E, according to the increase of whey powder content. For alcohol content, the average values were 0.863%, 0.967%, 0.890%, 1.290%, and 1.313% for the control and samples B, C, D, and E, respectively. As the dosage of whey powder increased, alcohol content showed a tendency to gradually increase. The average alcohol content of E was 1.313 and this was higher than the alcohol content of Kazahstana-type Koumiss with 1.08%. Sixteen types of free amino acids were detected. Glycine was the lowest in the control at $0.38mg/m{\ell}$ and sample E contained $0.64mg/m{\ell}$. Histidine was also low in the control at $0.42mg/m{\ell}$ and sample E contained $0.65mg/m{\ell}$. On the other hand, glutamic acid was highest at $4.13mg/m{\ell}$ in the control whereas sample E had $6.96mg/m{\ell}$. Proline was also high in the control at $1.71mg/m{\ell}$ in control, but E contained $2.80mg/m{\ell}$. Aspartic acid and leucine were greater in sample E than in the control. For volatile free fatty acids, content generally had a tendency to increase in the control, and samples B, C, D, and E. Content of acetic acid gradually increased from $12,661{\mu}g/100m{\ell}$ in the control to $37,140{\mu}g/m{\ell}$ in sample E. Butyric acid was not detected in the control and was measured as $1,950{\mu}g/100m{\ell}$ in sample E. Caproic acid content was $177{\mu}g/100m{\ell}$ in the control and $812{\mu}g/100m{\ell}$ in sample E, and it increased according to the increase of whey powder content. Valeric acid was measured in a small amount in the control as $22{\mu}g/100m{\ell}$, but it was not detected in any other case. Mineral contents of Ca, P, and Mg increased from 1,042.38 ppm, 863.61 ppm, and 101.28 ppm in the control to 1,535.12 ppm, 1,336.71 ppm, and 162.44 ppm in sample E, respectively. Na content was increased from 447.19 ppm in the control to 1,001.57 ppm in sample E. The content of K was increased from 1,266.39 ppm in the control to 2,613.93 ppm in E. Mineral content also increased with whey powder content. In sensory evaluations, the scores increased as whey powder content increased. Flavor was lowest in the control with 6.3 points and highest in E with 8.2 points. Body and texture were highest at 4.2 points in the control, which did not have added whey powder. In the case of appearance, there were no great differences among the samples.

A Compact Metamaterial Chip Antenna with Ground Coupling Structure for Bluetooth Application (Ground Coupling 구조를 이용한 초소형 Metamaterial Bluetooth 칩 안테나)

  • Park, Young-Hwan;Lee, Kang-Hee;Ji, Jeong-Keun;Ryu, Ji-Woong;Kim, Gi-Ho;Seong, Won-Mo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.20 no.9
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    • pp.930-935
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    • 2009
  • This paper describes a miniaturezed metamaterial BT chip antenna for mobile devices. The size of the proposed antenna is $3.0\;mm(W){\times}2.0\;mm(L){\times}1.2\;mm(H)$. And it is fabricated by chip type. The zeroth-order resonant properties are analyzed by magnitude and phase distributions of the surface current using surface current scanning system. The antenna offers omni-directional radiation patterns and measured 3D average gain is over - 1.7 dBi.

Une étude pour la critique de théâtre avec la sémiotique ouverte -avec par Jean Genet- (열린 기호학을 활용한 연극비평 연구 -장 주네의 <하녀들> 공연을 중심으로-)

  • LIM, Seon-Ok
    • Journal of Korean Theatre Studies Association
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    • no.40
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    • pp.239-275
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    • 2010
  • Cette ${\acute{e}}tude$ a pour but de proposer une $m{\acute{e}}thodologie$ de critique avec la $s{\acute{e}}miotique$ ouverte. La critique de $th{\acute{e}}{\hat{a}}tre$ commence ${\grave{a}}$ lire le $th{\acute{e}}{\hat{a}}tre$, l'analyse et juge son valeur. Il arrive souvent qu'on juge avec intutition. On dit que c'est une critique d'impressionnisme. Cette critique est subjective, mais pas objective. La $s{\acute{e}}miotique$ de Saussure offre la $m{\acute{e}}thodologie$ scientifique ${\grave{a}}$ la critique. A $c{\hat{o}}t{\acute{e}}$ de la critique d'impressionnisme qui est subjective, la $s{\acute{e}}miotique$ peut expliciter la raison objective. On ${\acute{e}}tait$ admiratif devant sa scientisme, pourtant $apr{\grave{e}}s$ quoi on critique sa non-$subjectivit{\acute{e}}$ et sa non-$historicit{\acute{e}}$. Dans l'opposition de $l^{\prime}objectivit{\acute{e}}$ et de la $subjectivit{\acute{e}}$, on tente de rechercher un model $int{\acute{e}}gr{\acute{e}}$ dialectiquement entre l'impressionisme(subjective) et la scientisme(objective). Pour cela, on doit aux Ecrits de linguistique $g{\acute{e}}n{\acute{e}}rale$ ($publi{\acute{e}}$ en 2002 chez Gallimard). Ces Ecrits nous aident ${\grave{a}}$ amener la $s{\acute{e}}miotique$ $ferm{\acute{e}}e$ sur la $s{\acute{e}}miotique$ ouverte et ${\grave{a}}$ $red{\acute{e}}couvrir$ la $pens{\acute{e}}e$ de Saussure. Ils nous font ouvrir un nouveau champ de recherche pour la $s{\acute{e}}miotique$ ouverte. L'essentiel de la $th{\acute{e}}orie$ saussurienne du signe $d{\acute{e}}pend$ de l'arbitraire et du circulaire du signe. On $red{\acute{e}}couvre$ la notion ${\acute{e}}largie$ du signe, dans Ecrits de linguistique $g{\acute{e}}n{\acute{e}}rale$, contre le courant majeur de linguistique et de structuralisme. Cette notion s'y focalise, ${\grave{a}}$ la valeur, ${\grave{a}}$ la $relativit{\acute{e}}$, ${\grave{a}}$ la $diff{\acute{e}}rence$ et au $syst{\grave{e}}me$. Avec elle, on tente d'adopter la $s{\acute{e}}miotique$ ouverte pour rechercher une $m{\acute{e}}thodologie$ de critique qui se veut objective et ${\grave{a}}$ la fois subjective. Il s'agit d'une difficile combinaison de l'impressionisme et de la scienticisme. Pour cela, la $m{\acute{e}}thodologie$ se $d{\acute{e}}veloppera$ en trois ${\acute{e}}tapes$. $1{\grave{e}}re$ ${\acute{e}}tape$: c'est lire le $th{\acute{e}}{\hat{a}}tre$ comme un signe total pour 1er jugement d'impressionnisme. $2{\grave{e}}me$ ${\acute{e}}tape$: c'est retrouver sa structure invisible dans la $relativit{\acute{e}}$ des signes. $3{\grave{e}}me$ ${\acute{e}}tape$: c'est juger, dans leur $relativit{\acute{e}}$, comment les $d{\acute{e}}tails$ de signes se fonctionnent. C'est lire les $d{\acute{e}}tails$ de signes et puis $r{\acute{e}}affirmer$ le jugement en $1{\grave{e}}re$ ${\acute{e}}tape$. Selon les $derni{\grave{e}}res$ deux ${\acute{e}}tapes$, on pourra comparer le premier jugement (impressif) et le dernier jugement (objectif), et enfin s'assumer comme critique. Selon la $m{\acute{e}}thodologie$ $propos{\acute{e}}e$, on pratique la critique sur ${\acute{e}}crit$ par Jean Genet, et mise en $sc{\grave{e}}ne$ par Lee Youn-Taek et par Park Jung-Hee. Pour la critique intertextuelle, on la fera en comparant les deux spectacles avec la $pi{\grave{e}}ce$ de Jean Genet. $D^{\prime}apr{\grave{e}}s$ la comparaison, Lee Youn-Taek met en $sc{\grave{e}}ne$ avec $fid{\acute{e}}lit{\acute{e}}$ la structre et les signes de $d{\acute{e}}tail$ de l'auteur, Park Jung-Hee change sa structre et ses signes pour mettre en $sc{\grave{e}}ne$ la $pi{\grave{e}}ce$ de Genet. Ils se $diff{\grave{e}}rent$ l'un et l'autre: Lee incite le discours de la classe sociale dans le spectacle, et Park y incite le discours du $d{\acute{e}}sir$. La $diff{\acute{e}}rence$ des signes dans la $relativit{\acute{e}}$ apporte la $diff{\acute{e}}rence$ de la signification de discours $th{\acute{e}}{\hat{a}}tral$, et enfin se font changer les significations de deux spectacles.