• Korean System Dynamics Review
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• v.1 no.2
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• pp.91-111
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• 2000

Causal maps or cognitive maps have been widely used to get insights for complex systems or decision makers. When insights come from the system behavior rather than its structure, we need simulation of causal maps and cognitive maps. In this paper, a method for directly converting causal maps and cognitive maps into stock-flow diagrams that can be simulated in computers in proposed. This method is called as NUMBER. NUMBER is an abbreviation for 'Normal Unit Modeling By Elementary Relationship'. In this paper, NUMBER is applied to a cognitive map of policy maker to show its usefulness.

• International Journal of Aeronautical and Space Sciences
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• v.16 no.4
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• pp.590-601
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• 2015

This paper gives an overview of research on the field of structure vibration-attitude coordinated control of spacecraft. First of all, the importance of the technology has been given an introduction, and then later the research progress of space structure dynamics modeling, research progress of structure vibration-attitude coordinated control of flexible spacecraft have been discussed respectively. Finally, future research on application of structure vibration-attitude coordinated control of spacecraft has been recommended.

• International Journal of Aeronautical and Space Sciences
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• v.15 no.4
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• pp.345-355
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• 2014

This paper focuses on aerodynamic and inertial modeling of the propeller for its applications in flight dynamics analyses of a propeller-driven airplane. Unsteady aerodynamic and inertial loads generated by the propeller are formulated using the blade element method, where the local velocity and acceleration vectors for each blade element are obtained from exact kinematic relations for general maneuvering conditions. Vortex theory is applied to obtain the flow velocities induced by the propeller wake, which are used in the computation of the aerodynamic forces and moments generated by the propeller and other aerodynamic surfaces. The vortex lattice method is adopted to obtain the induced velocity over the wing and empennage components and the related influence coefficients are computed, taking into account the propeller induced velocities by tracing the wake trajectory trailing from each of the propeller blades. Aerodynamic forces and moments of the fuselage and other aerodynamic surfaces are computed by using the wind tunnel database and applying strip theory to incorporate viscous flow effects. The propeller models proposed in this paper are applied to predict isolated propeller performances under steady flight conditions. Trimmed level forward and turn flights are analyzed to investigate the effects of the propeller on the flight characteristics of a propeller-driven light-sports airplane. Flight test results for a series of maneuvering flights using a scaled model are employed to run the flight dynamic analysis program for the proposed propeller models. The simulations are compared with the flight test results to validate the usefulness of the approach. The resultant good correlations between the two data sets shows the propeller models proposed in this paper can predict flight characteristics with good accuracy.

• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.869-880
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• 2012

Identification of the selective chemical features for Aurora-B inhibitors gained much attraction in drug discovery for the treatment of cancer. Hence to identify the Aurora-B critical features various techniques were utilized such as pharmacophore generation, virtual screening, homology modeling, molecular dynamics, and docking. Top ten hypotheses were generated for Aurora-B and Aurora-A. Among ten hypotheses, HypoB1 and HypoA1 were selected as a best hypothesis for Aurora-B and Aurora-A based on cluster analysis and ranking score, respectively. Test set result revealed that ring aromatic (RA) group in HypoB1 plays an essential role in differentiates Aurora-B from Aurora-A inhibitors. Hence, HypoB1 used as 3D query in virtual screening of databases and the hits were sorted out by applying drug-like properties and molecular docking. The molecular docking result revealed that 15 hits have shown strong hydrogen bond interactions with Ala157, Glu155, and Lys106. Hence, we proposed that HypoB1 might be a reasonable hypothesis to retrieve the structurally diverse and selective leads from various databases to inhibit Aurora-B.

• Genomics & Informatics
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• v.13 no.1
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• pp.15-24
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• 2015

Fatty acid synthase (FASN, EC 2.3.1.85), is a multi-enzyme dimer complex that plays a critical role in lipogenesis. This lipogenic enzyme has gained importance beyond its physiological role due to its implications in several clinical conditions-cancers, obesity, and diabetes. This has made FASN an attractive pharmacological target. Here, we have attempted to predict the theoretical models for the human enoyl reductase (ER) and ${\beta}$-ketoacyl reductase (KR) domains based on the porcine FASN crystal structure, which was the structurally closest template available at the time of this study. Comparative modeling methods were used for studying the structure-function relationships. Different validation studies revealed the predicted structures to be highly plausible. The respective substrates of ER and KR domains-namely, trans-butenoyl and ${\beta}$-ketobutyryl-were computationally docked into active sites using Glide in order to understand the probable binding mode. The molecular dynamics simulations of the apo and holo states of ER and KR showed stable backbone root mean square deviation trajectories with minimal deviation. Ramachandran plot analysis showed 96.0% of residues in the most favorable region for ER and 90.3% for the KR domain, respectively. Thus, the predicted models yielded significant insights into the substrate binding modes of the ER and KR catalytic domains and will aid in identifying novel chemical inhibitors of human FASN that target these domains.

• Proceedings of the Korea Society for Simulation Conference
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• 2001.10a
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• pp.453-458
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• 2001

A mobile agent is an autonomous software agent capable of moving from one computer to another while performing its tasks. We view the agent as a discrete event system in the view of its computation and communication. This paper presents a methodology far modeling and simulation of such a mobile agent system as a discrete event system. The methodology is based on the Mobile Discrete Event System Specification (MDEVS) formalism and the associated simulation environment AgentSim which are previously developed by the authors. Within the methodology an atomic model represents dynamics of a mobile agent; a coupled model is modeled as mobile agent servers for representation of structural changes between atomic agents. Being based on the object-oriented environment the modeling methodology exploits inheritance of basic classes AtomicModel and CoupledModel provided by AgentSim.

• The Transactions of the Korean Institute of Power Electronics
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• v.17 no.1
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• pp.67-76
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• 2012

This paper proposes the aggregated modeling and control of integated boost-flyback converter (IBFC) for understanding of dynamics characteristic and designing of relevant controller. The basic concept of the aggregated modeling is to substitute the boost or the flyback converter with an equivalent current source. Since each converter with equivalent current source corresponds to the basic boost and flyback converters, the overall mathematical process is significantly simplified for the modeling. Afterwards each result is combined to construct the complete model of the IBFC, and the relevant controller is designed through the achieved small-signal model. Simulation and experimental results show excellent agreement with the theoretical expectations.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.7
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• pp.1007-1013
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• 2012

Modeling of photovoltaic power systems is significant to analytically predict its dynamics in practical applications. This paper presents a novel modeling algorithm of such system by using probability and statistic theories. We first establish a linear model basically composed of Fourier parameter sets for mapping the input/output variable of photovoltaic systems. The proposed model includes solar irradiation and ambient temperature of photovoltaic modules as an input vector and the inverter power output is estimated sequentially. We deal with these measurements as random variables and derive a parameter learning algorithm of the model in terms of statistics. Our learning algorithm requires computation of an expectation and joint expectation against solar irradiation and ambient temperature, which are analytically solved from the integral calculus. For testing the proposed modeling algorithm, we utilize realistic measurement data sets obtained from the Seokwang Solar power plant in Youngcheon, Korea. We demonstrate reliability and superiority of the proposed photovoltaic system model by observing error signals between a practical system output and its estimation.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.10a
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• pp.557-561
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• 2014

In this work, Altair Engineering's vibroacoustic modeling approach is used to simulate the acoustic signature of a simplified automobile in a wind tunnel. The modeling approach relies on a two step procedure involving simulation and extraction of acoustic sources using a high fidelity Computational Fluid Dynamics (CFD) simulation followed by propagation of the acoustic energy within the structure and passenger compartment using a structural dynamics solver. The tools necessary to complete this process are contained within Altair's HyperWorks CAE software suite. The CFD simulations are performed using AcuSolve and the structural simulations are performed using OptiStruct. This vibroacoustics simulation methodology relies on calculation of the acoustic sources from the flow solution computed by AcuSolve. The sources are based on Lighthill's analogy and are sampled directly on the acoustic mesh. Once the acoustic sources have been computed, they are transformed into the frequency domain using a Fast Fourier Transform (FFT) with advanced sampling and are subsequently used in the structural acoustics model. Although this approach does require the CFD solver to have knowledge of the acoustic simulation domain a priori, it avoids modeling errors introduced by evaluation of the acoustic source terms using dissimilar meshes and numerical methods. The aforementioned modeling approach is demonstrated on the Hyundai Simplified Model (HSM) geometry in this work. This geometry contains flow features that are representative of the dominant noise sources in a typical automobile design; namely vortex shedding from the passenger compartment A-pillar and bluff body shedding from the side view mirrors. The geometry also contains a thick poroelastic material on the interior that acts to reduce the acoustic noise. This material is modeled using a Biot material formulation during the structural acoustic simulation. Successful prediction of the acoustic noise within the HSM geometry serves to validate the vibroacoustic modeling approach for automotive applications.

• Journal of the Korea Society for Simulation
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• v.17 no.1
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• pp.33-42
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• 2008

In general, simulation is to predict or evaluate some systems that are hard to be executed in real world, and so usually the target systems to be modeled are large and complex. Trying to observe the dynamics of the systems results in similar level of animation complexity, the model and animation has the same complexity as the system. Trying to display all the graphic objects representing the dynamics of the models being simulated, however, causes the distraction of focus, which results in solving the above listed problems difficult. The redundant graphic objects also increase the computer computation overhead. To solve the problem, a research about a hierarchical animation environment has been proposed a few years ago. In the research, the users can have better focus on the dynamics of system components by selectively choosing the hierarchical level and components within a level of the hierarchically structured model. However, the research has not a modeling methodology for modelers to describe systematically animation part corresponding to dynamics of simulation in a model. This research has defined the modeling methodology of DESHA and defined DESHA-C++, improving the previous research output, as an execution environment of DESHA models. In addition, to use hierarchical animation environment in various problems, this research proposed and developed the distributed simulation modeling environment that connects DESHA environment and HLA.