• 제목/요약/키워드: Dynamic light scattering

검색결과 185건 처리시간 0.028초

경량 동적 코드 변환 기법을 이용한 동적 인스트루멘테이션 기법 설계 및 구현 (Design and Implementation of a Dynamic Instrumentation Framework based on Light-weight Dynamic Binary Translation)

  • 김지홍;이동우;김인혁;엄영익
    • 정보과학회 논문지
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    • 제41권11호
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    • pp.892-899
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    • 2014
  • 동적 인스트루멘테이션 기법은 동적 코드 변환 기법을 사용하여 프로그램의 수행 흐름을 흐트러뜨리지 않으면서 분석 코드를 삽입하는 구현 기법으로 사용되고 있다. 기존의 동적 코드 변환 기법은 머신 코드 스트림을 중간 코드 형태로 파싱하고, 이를 일반적인 컴파일러 기법에 적용함으로써 코드를 변환한다. 이러한 방식의 코드 변환 과정에서 수반되는 높은 변환 오버헤드는 응답성이 높은 사용자 프로그램에 적용을 어렵게 한다. 본 논문에서는 변환 과정의 경량화를 통해 변환 오버헤드를 줄임으로써, 높은 동적 코드 변환 성능을 가지는 경량 동적 코드 변환 기법을 제안하고, 이를 기반으로 하는 동적 인스트루멘테이션 프레임워크를 제안한다. 제안 기법은 테이블 기반의 새로운 동적 주소 변환 기법으로 코드를 변환하고, 더불어 자주 실행되는 라이브러리 함수에 대해 변환 과정에 대해서는 주소 변환만을 함으로써 변환 오버헤드를 줄이는 변환 우회 기법을 이용한다. 기존 동적 코드 변환 기법과의 비교를 통해 2%~65%의 성능 향상을 확인하였다.

Spontaneous Nanoparticle Formation From a Fluorescent Nucleoside Analogue

  • Bang, Eun-Kyoung;Moon, Do-Hyun;Kim, Byeang-Hyean
    • Bulletin of the Korean Chemical Society
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    • 제32권spc8호
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    • pp.2906-2910
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    • 2011
  • A fluorescent nucleoside analogue, $^AC$, featuring two non-complementary nucleobases linked through an ethynyl group, was synthesized. The extended ${\pi}$-conjugation imparts $^AC$ with red-shifted absorbance (relative to adenine and cytosine) and pale-blue fluorescence. It spontaneously forms nanoparticles, which exhibit considerably enhanced fluorescence, without the help of any additional stabilizing agent. The DMSO/water ratio was an important factor influencing the construction of the NPs. X-ray crystallography confirmed the structure of $^AC$; dynamic light scattering and scanning electron microscopy confirmed the existence of the nanoparticles.

Characterization of Linear Polymer-Dendrimer Block Copolymer/Plasmid DNA Complexes: Formation of Core-shell Type Nanoparticles with DNA and Application to Gene Delivery in Vitro

  • Choi, Joon-Sig;Choi, Young-Hun;Park, Jong-Sang
    • Bulletin of the Korean Chemical Society
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    • 제25권7호
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    • pp.1025-1030
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    • 2004
  • A hybrid linear polymer-dendrimer block copolymer, poly(ethylene glycol)-block-poly(L-lysine) dendrimer, was synthesized and introduced to form polyionic complexes with DNA. The copolymer formed core-shell type nanoparticles with plasmid DNA. From dynamic light scattering experiments, the mean diameter of the polyplexes was observed to be 154.4 nm. The complex showed much increased water solubility compared to poly(L-lysine). The plasmid DNA in polyplexes was efficiently protected from the enzymatic digestion of DNase I. The cytotoxicity and transfection efficiency for 293 cells was measured in comparison with poly(Llysine).

Microbial Production and Characterization of Superparamagnetic Magnetite Nanoparticles by Shewanella sp. HN-41

  • Lee, Ji-Hoon;Roh, Yul;Hur, Hor-Gil
    • Journal of Microbiology and Biotechnology
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    • 제18권9호
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    • pp.1572-1577
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    • 2008
  • A facultative dissimilatory metal-reducing bacterium, Shewanella sp. strain HN-41, was used to produce magnetite nanoparticles from a precursor, poorly crystalline iron-oxyhydroxide akaganeite ($\beta$-FeOOH), by reducing Fe(III). The diameter of the biogenic magnetite nanoparticles ranged from 26 nm to 38 nm, characterized by dynamic light scattering spectrophotometry. The magnetite nanoparticles consisted of mostly uniformly shaped spheres, which were identified by electron microscopy. The magnetometry revealed the superparamagnetic property of the magnetic nanoparticles. The atomic structure of the biogenic magnetite, which was determined by extended X-ray absorption fine structure spectroscopic analysis, showed similar atomic structural parameters, such as atomic distances and coordinations, to typical magnetite mineral.

Three-Dimensional Self-Assembly of Gold Nanoparticles Using a Virus Scaffold

  • Kang, Aeyeon;Lee, Young-Mi;Kang, Hyo Jin;Chung, Sang Jeon;Yun, Wan Soo
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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    • pp.651-651
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    • 2013
  • Templated strategy is a very powerful tool for creating multi-dimensional self assembly of nanomaterials. Since viral protein cages have a uniform size with a well-defined structure, they can serve as an excellent template for the formation of a three-dimensional self-assembly of synthetic nanoparticles. In this study, we have examined the feasibility of the 3D self-assembly of gold nanoparticles of various sizes using a brome mosaic virus (BMV) capsid with cysteine groups expressed on its surface as a scaffold for the assembly. It was found that the three-dimensional clusters of gold nanoparticles with a designed structure were attainable by this approach, which was verified by transmission electron microscope (TEM) and dynamic light scattering (DLS) analysis.

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Thermodynamics of the binding of Substance P to lipid membranes

  • Lee, Woong Hyoung;Kim, Chul
    • 분석과학
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    • 제30권2호
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    • pp.89-95
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    • 2017
  • The thermodynamic functions for the binding of the peptide Substance P (SP) on the surface of lipid vesicles made of various types of lipids were obtained by using isothermal titration calorimetry. The reaction enthalpies measured from the experiments were -0.11 to $-4.5kcal\;mol^{-1}$. The sizes of the lipid vesicles were measured with dynamic light scattering instrument in order to get the correlation between the reaction enthalpies and the vesicle sizes. The bindings of SP on the lipid vesicles with diameter of 37 to 108 nm were classified into the enthalpy-driven reaction or the entropy-driven reaction according to the size of the lipid vesicles. For the enthalpy-driven binding reaction, the significance of the electrostatic interactions between SP and lipid molecules was affirmed from the experimental results of the DMPC/DMPG/DMPH and DMPC/DMPS/DMPH vesicles as well as the importance of the hydrophobic interactions between hydrophobic groups of SP and lipid molecules.

Chemical synthesis of processable conducting polyaniline derivative with free amine functional groups

  • Kar, Pradip
    • Advances in materials Research
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    • 제3권2호
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    • pp.117-128
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    • 2014
  • Processable conducting polyaniline derivative with free amine functional groups was successfully synthesized from the monomer o-phenylenediamine in aqueous hydrochloric acid medium using ammonium persulfate as an oxidative initiator. The synthesized poly(o-phenylenediamine) (PoPD) in critical condition was found to be completely soluble in common organic solvents like dimethyl sulfoxide, N,N-dimethyl formamide etc. From the intrinsic viscosity measurement, the optimum condition for the polymerization was established. The polymer was characterized by ultraviolet visible spectroscopy, Fourier transform infrared spectroscopy, proton magnetic resonance spectroscopy ($^1HNMR$) and thermogravimetric (TGA) analyses. The weight average molecular weights of the synthesized polymers were determined by the dynamic light scattering (DLS) method. From the spectroscopic analysis the structure was found to resemble that of polyaniline derivative with free amine functional groups attached to ortho/meta position in the phenyl ring. However, very little ladder unit was also present with in the polymer chain. The moderate thermal stability of the synthesized polymer could be found from the TGA analysis. The average DC conductivity of $2.8{\times}10^{-4}S/cm$ was observed for the synthesized polymer pellet after doping with hydrochloric acid.

Synthesis of gold nanoparticles using Coffea Arabica fruit extract

  • Bogireddy, Naveen Kumar Reddy;Gomez, L. Martinez;Osorio-Roman, I.;Agarwal, V.
    • Advances in nano research
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    • 제5권3호
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    • pp.253-260
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    • 2017
  • We report a simple eco-friendly process for the synthesis of gold nanoparticles (AuNPs) using aqueous extract from Coffea Arabica fruit. The formation of AuNPs was confirmed using absorption spectroscopy and scanning electron microscopy images. FT-IR analysis demonstrates the major functional groups present in Coffee Arabica fruit extract before and after synthesizing AuNPs. The Face Center Cubic (FCC) polycrystalline nature of these particles was identified by X-Ray diffraction (XRD) analysis. Taking into account the contribution of the biomass surrounding the AuNPs, dynamic light scattering (DLS) results revealed an average particle size of ~59 nm.

Synthesis and Thermo-mechanical Property of Multi-walled Carbon Nanotubes/Poly(methyl methacrylate-co-butyl acrylate) Nanocomposites Prepared Using Emulsion Polymerizations in the Presence of Amphiphilic Random Terpolymer

  • Chang, Woo-Hyuck;Ki, Ho-Seong;Cheong, In-Woo
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.289-289
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    • 2006
  • The carboxylated MWNTs were successfully prepared by conventional acid treatment, and their structures were confirmed by FT-IR, Raman and TEM analysis. The water-dispersibility of the surface modified WNTs were good. The COOH-MWNT will show better stability during the emulsion polymerization as compared with Pristine MWNT. In-situ emulsion polymerizations of methyl methacrylate N(MMA) and n-butyl acrylate (BA) were carried out. Aggregate size and dispersion stability of the CNTs in water phase were measured using dynamic light scattering, turbidity, UV-visible spectrophotometer, and electron microscope. In addition, thermo-mechanical properties of MWNT/polymer nanocomposites were investigated.

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Fabrication of nanoaggregates of triple hydrophilic block copolymers by binding of ionic surfactants

  • Khanal, Anil;Yusa, Shin-Ichi;Nakashima, Kenichi
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.302-302
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    • 2006
  • Nanoaggregates of triple hydrophilic block copolymers comprised of poly(ethylene oxide), poly(sodium 2-acrylamido)-2-methylpropanesulfonate), and poly(methacrylic acid) (PEO-PAMPS-PMAA) and the cationic surfactant, dodecyltrimethylammonium chloride (DTAC) have been fabricated. The formation of $^{\circ}^{\circ}$the nanoaggregates is based on electrostatic interaction of sulfonate and carboxylate groups of PAMPS and PMAA blocks with the cationic surfactant, which results in insolubilization of these blocks. The formation of micelle is observed by dynamic light scattering measurements. Binding of DTAC to the anionic blocks of PEO-PAMPS-PMAA is confirmed by electrophoresis measurements.

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