• Title/Summary/Keyword: Dynamic Range

Search Result 2,971, Processing Time 0.03 seconds

Electrochemical Study on Transfer Reaction of Ionizable Cefotiam across a Water/1,2-dichloroethane Interface and Drug Sensing Applications (물/1,2-Dichloroethane 계면에서 Cefotiam 약물 이온의 전이 반응 연구 및 약물 센서에 응용)

  • Liu, XiaoYun;Jeshycka, Shinta;Lee, Hye Jin
    • Applied Chemistry for Engineering
    • /
    • v.29 no.5
    • /
    • pp.581-588
    • /
    • 2018
  • In this article, electrochemical investigation of the transfer reaction of ionizable cefotiam (CTM), an antibiotic molecule across a polarized water/1,2-dichloroethane (water/1,2-DCE) interface was studied. Ion partition diagram providing the preferred charged form of CTM in either water or 1,2-DCE phase was established via the voltammetric evaluation of the transfer process of differently charged CTM species depending upon the pH variation of aqueous solutions. Thermodynamic information including the formal transfer potential and formal Gibbs transfer energy values in addition to important pharmacokinetics including partition coefficients of ionizable CTM were also evaluated. In particular, the current associated with the transfer of CTM present at pH 3.0 aqueous solution proportionally increased with respect to the CTM concentration which was further used for developing CTM sensitive ion sensor. In order to improve the portability and convenient usage, a single microhole interface fabricated in a supportive polyethylene terephthalate film was used of which hole was filled with a polyvinylchloride-2-nitrophenyloctylether (PVC-NPOE) gel replacing 1,2-DCE, a toxic organic solvent. A dynamic range of $1-10{\mu}M$ CTM was obtained.

The use of SMA wire dampers to enhance the seismic performance of two historical Islamic minarets

  • El-Attar, Adel;Saleh, Ahmed;El-Habbal, Islam;Zaghw, Abdel Hamid;Osman, Ashraf
    • Smart Structures and Systems
    • /
    • v.4 no.2
    • /
    • pp.221-232
    • /
    • 2008
  • This paper represents the final results of a research program sponsored by the European Commission through project WIND-CHIME ($\underline{W}$ide Range Non-$\underline{IN}$trusive $\underline{D}$evices toward $\underline{C}$onservation of $\underline{HI}$storical Monuments in the $\underline{ME}$diterranean Area), in which the possibility of using advanced seismic protection technologies to preserve historical monuments in the Mediterranean area is investigated. In the current research, the dynamic characteristics of two outstanding Mamluk-Style minarets, which similar minarets were reported to experience extensive damage during Dahshur 1992 earthquake, are investigated. The first minaret is the Qusun minaret (1337 A.D, 736 Hijri Date (H.D)) located in El-Suyuti cemetery on the southern side of the Salah El-Din citadel. The minaret is currently separated from the surrounding building and is directly resting on the ground (no vaults underneath). The total height of the minaret is 40.28 meters with a base rectangular shaft of about 5.42 ${\times}$ 5.20 m. The second minaret is the southern minaret of Al-Sultaniya (1340 A.D, 739 H.D). It is located about 30.0 meters from Qusun minaret, and it is now standing alone but it seems that it used to be attached to a huge unidentified structure. The style of the minaret and its size attribute it to the first half of the fourteenth century. The minaret total height is 36.69 meters and has a 4.48 ${\times}$ 4.48 m rectangular base. Field investigations were conducted to obtain: (a) geometrical description of the minarets, (b) material properties of the minarets' stones, and (c) soil conditions at the minarets' location. Ambient vibration tests were performed to determine the modal parameters of the minarets such as natural frequencies and mode shapes. A $1/16^{th}$ scale model of Qusun minaret was constructed at Cairo University Concrete Research Laboratory and tested under free vibration with and without SMA wire dampers. The contribution of SMA wire dampers to the structural damping coefficient was evaluated under different vertical loads and vibration amplitudes. Experimental results were used along with the field investigation data to develop a realistic 3-D finite element model that can be used for seismic risk evaluation of the minarets. Examining the updated finite element models under different seismic excitations indicated the vulnerability of such structures to earthquakes with medium to high a/v ratio. The use of SMA wire dampers was found feasible for reducing the seismic risk for this type of structures.

A Study on the Evaluation of Track Support Stiffness on the Various Track Type in Urban Transit (도시철도 궤도구조별 궤도지지강성 평가를 위한 실험적 연구)

  • Lee, Dong-Wook;Park, Yong-Gul;Choi, Jung-Youl
    • Journal of the Korean Society for Railway
    • /
    • v.14 no.3
    • /
    • pp.262-270
    • /
    • 2011
  • Track support stiffness which affected track maintenance and riding comfort had a big effect on the track and train. Also, track support stiffness of the track design which was based on theory differs from track support stiffness of the track generated on the field. Track support stiffness was generated by several factors such as dynamic wheel loads, vertical displacement of track, and stress at rail bottom on the field test. With the results of the field test was compared with theoretical value. This paper analyzed that track support stiffness of ballast depended on condition of ballast, and support stiffness of concrete track also depended on the characteristic of track structures such as, normal elastic fastening system, rail floating system and sleeper floating system. However, on the ballast and concrete track, the designed track support stiffness was underestimated less than the measured track support stiffness. When the track condition was estimated on service line, it would not consider the track condition on the field. Therefore, this study proposed the various track type and the range of track support stiffness based on the experimental test.

Estimation of the relationship between below-ground root and above-ground canopy development by measuring dynamic change of soil ammonium-N concentration in rice

  • Fushimi, Erina;Yoshida, Hiroe;Tokida, Takeshi;Nakagawa, Hiroshi
    • Proceedings of the Korean Society of Crop Science Conference
    • /
    • 2017.06a
    • /
    • pp.183-183
    • /
    • 2017
  • In the early part of rice growth, root volume primarily limits the amount of plant-accessible nitrogen (N). Therefore, knowledge of the root development is important for modeling N uptake of rice. The timing when the volume of rhizosphere cover the whole soil is also important to carry out timely top dressing. However, information about initial root expansion and associated N uptake is limited due to intrinsic technical difficulties in assessing below-ground processes. Some studies, however, showed a close relationship between below-ground root and above-ground leaf development, suggesting a possibility that above-ground attributes could serve as surrogates for the root processes. In this study, we investigated the relationship between below-ground and above-ground development of rice. Field experiments were conducted where we cultivated Koshihikari (a leading cultivar in Japan) for four different cropping schedules in 2012. In 2016, Gimbozu (HEG4) and three flowering time mutant lines of Gimbozu (X61 (se13), HS276 (ef7), DMG9 (se13, ef7)) were examined for a single season. Experiments were performed with three replications in a completely randomized design. We monitored ammonium-N concentration ([NH4+-N]) in soil solution by repeatedly taking samples from a porous tubing (10-cm long) vertically inserted at the most distant point from surrounding rice hills. Samples were taken in triplicate (= triplicate tubes) and every three days from transplanting in each experimental unit. For above-ground attributes, leaf area index (LAI) was measured in 2012, whereas soil coverage ratio was estimated by image processing in 2016. Results showed that [NH4+-N] increased gradually after transplanting and then rapidly decreased from a certain day. This distinct drop in [NH4+-N] informed us the timing at which the rice root system reached the point of porous tubing and thus essentially covered the whole soil volume. The LAI at the dropping point was about 0.43 regardless of the cropping schedules in 2012 experiment. In 2016, the coverage ratio at the N dropping point was within the range of 0.12 to 0.19 for four genotypes having different growth durations. In addition, the coverage ratios at seven weeks after the transplanting showed a good correspondence to LAI across the four genotypes. We therefore conclude that both LAI and coverage ratio may serve as robust indicators for root development and might be useful to estimate the timing when the root system fully cover the soil volume. Results obtained here will also contribute to develop models that can predict not only above-ground canopy development but also associated below-ground processes.

  • PDF

Circulation Dynamics of Keum River Estuary II. Fluid Dynamic Characteristics (錦江 河口의 海水循環力學 弟2報 流體力學的 諸特性)

  • Chung, Jong Yul;Bhang, In Kweon
    • 한국해양학회지
    • /
    • v.19 no.2
    • /
    • pp.141-152
    • /
    • 1984
  • In order to investigate the circulation dynamics of the Keum River estuary, 300velocity fields obtained at six sites over two tidal cycles by using instantaneous profiling technique were analyzed in detail. In this investigation, the variability of shear velocity, bottom shear stress, drag coefficient, and roughness length scale were confirmed. The measured values of the bottom boundary drag coefficient show wide range of variations, i.e., C$\_$100/=6.78${\times}$10$\^$-5/∼1.15${\times}$10$\^$-1/, and the mean of 300 measurements is 1.6${\times}$10$\^$-2/. The relationship between U* and C$\_$100/ also show the scatter in values. However, overall mean values over two tidal cycles at 6 stations show that if U* 1cm/s, C$\_$100/ is unpredictable, if U* 1cm/s, C$\_$100/ increase with U*. The values of Re$\_$100/ and C$\_$100/ have scatter. But the overall mean values over two tidal cycles show that if Re$\_$100/ 3.6${\times}$10$\^$5/, C$\_$100/ is unpredictable, if Re$\_$100/ 3.6${\times}$10$\^$5/, C$\_$100/=1.4${\times}$10$\^$-2/. Finally the flow regime of the Keum River estuary was classified as "subcritical fully turbulent" flow.

  • PDF

Effects of Skill Level and Feet Width on Kinematic and Kinetic Variables during Jump Rope Single Under

  • Jang, Kyeong Hui;Son, Min Ji;Kim, Dae Young;Lee, Myeoung Gon;Kim, You Kyung;Kim, Jin Hee;Youm, Chang Hong
    • Korean Journal of Applied Biomechanics
    • /
    • v.27 no.2
    • /
    • pp.99-108
    • /
    • 2017
  • Objective: The purpose of this study was to analyze the effects of skill level and width between feet on kinematic and kinetic variables during jump rope single under with both feet. Method: Fifteen subjects in the skilled group (age: $10.85{\pm}0.40yrs$, height: $142.13{\pm}5.41cm$, weight: $36.97{\pm}6.65kg$) and 15 subjects in the unskilled group (age: $10.85{\pm}0.40yrs$, height: $143.31{\pm}5.54cm$, weight: $40.81{\pm}10.39kg$) participated in this study. Results: Participants in the skilled group minimized the anteroposterior displacement of their center of mass by modifying the width between their feet and decreased the range of motion (ROM) of their trunk in the sagittal plane. The preferred width during the jump rope decreased by 5.61~6.11 cm (32~37%) in comparison to width during static standing. The induced width was increased by 16.44~16.67 cm (82~85%), regardless of skill level. The kinematic variables of the left and right legs of members of the unskilled group were significantly different from those of members in the skilled group regarding the ROM of the hip, knee, and ankle joint. Otherwise, the members of the skilled group were consistent in terms of the kinematic variables of the right and left legs. Conclusion: The preferred width between feet during the jump rope was found to be beneficial for maintaining dynamic stability. The unskilled group exhibited asymmetry in left and right motion within the ranges of motion of the ankle, knee, and hip joints, regardless of the width. Therefore, long-term accurate jump rope motions will contribute to an improvement in the left and right imbalances of the entire body.

Design of a Fourth-Order Sigma-Delta Modulator Using Direct Feedback Method (직접 궤환 방식의 모델링을 이용한 4차 시그마-델타 변환기의 설계)

  • Lee, Bum-Ha;Choi, Pyung;Choi, Jun-Rim
    • Journal of the Korean Institute of Telematics and Electronics C
    • /
    • v.35C no.6
    • /
    • pp.39-47
    • /
    • 1998
  • A fourth-order $\Sigma$-$\Delta$ modulator is designed and implemented in 0.6 $\mu\textrm{m}$ CMOS technology. The modulator is verified by introducing nonlinear factors such as DC gain and slew rate in system model that determines the transfer function in S-domain and in time-domain. Dynamic range is more than 110 dB and the peak SM is 102.6 dB at a clock rate of 2.8224 MHz for voiceband signal. The structure of a ∑-$\Delta$ modulator is a modified fourth-order ∑-$\Delta$ modulator using direct feedback loop method, which improves performance and consumes less power. The transmission zero for noise is located in the first-second integrator loop, which reduces entire size of capacitors, reduces the active area of the chip, improves the performance, and reduces power dissipation. The system is stable because the output variation with respect to unit time is small compared with that of the third integrator. It is easy to implement because the size of the capacitor in the first integrator, and the size of the third integrator is small because we use the noise reduction technique. This paper represents a new design method by modeling that conceptually decides transfer function in S-domain and in Z-domain, determines the cutoff frequency of signal, maximizes signal power in each integrator, and decides optimal transmission-zero frequency for noise. The active area of the prototype chip is 5.25$\textrm{mm}^2$, and it dissipates 10 mW of power from a 5V supply.

  • PDF

MR Technology to 4T

  • Vaughan, Thomas
    • Proceedings of the KSMRM Conference
    • /
    • 2003.10a
    • /
    • pp.103-105
    • /
    • 2003
  • After fifteen years of development, Magnetic Resonance (MR) technology for human imaging and spectroscopy is reaching a refined state with FDA approved 3T clinical products from Siemens, GE, and Philips. Broker has cleared CE approval with a 4T system. Varian supports a 4T system platform as well. Shielded magnets are standard at 3T from GE, Oxford, Magnex, and IGC. A shielded 4T whole body magnet is available from Oxford. Stronger switched gradients and dynamic shim coils, desired at any field, areespecially useful at higher static magnetic fields B0. In addition to the higher currents required for higher resolution slice or volume selection afforded by higher SNR, whole body gradient coils will be driven at increasing slew rates to meet the needs of new cardiac applications and other requirements. For example 3T and 4T systems are now being equipped with 2kV, 500A gradient coils and amplifiers capable of generating 4G/cm in 200msec, over a 67+/-cm bore diameter. High field EPI applications require oscillation rates at 1 kHz and higher. To achieve a benchmark 0.2 ppm shim over a 30cm sphere in a high field magnet, at least four stages of shimming need to be considered. 1) A good high field magnet will be built to a homogeneity spec. falling in the range of 100 to 150 ppm over this 30cm spherical "sweet spot" 2) Most modern high field magnets will also have superconducting shim coils capable of finding 1.5 ppm by their adjustment during system installation. 3) Passive ferro-magnetic shimming combined with 4) active, high order room temperature shim coils (as many as five orders are now being recommended) will accomplish 0.2 ppm over the 30cm sphere, and 0.1 ppm over a human brain in even the highest field magnets for human studies. Safety concerns for strong, fast gradients at any B0 field include acoustic noise and peripheral nerve stimulation. One or more of the mechanical decoupling methods may lead to quieter gradients. Patient positioning relative to asymmetric or short gradient coils may limit peripheral nerve stimulation at higher slew rates. Gradient designs combining a short coil for local speed and strength with a longer coil for coverage are being developed for 3T systems. Local gradients give another approach to maximizing performance over a limited region while keeping within the physiologically imposed dB0/dt performance limits.

  • PDF

Evaluation of Dual-channel Compound Method for EBT3 Film Dosimetry

  • Kang, Sang-Won;Chung, Jin-Beom;Kim, Kyeong-Hyeon;Eom, Keun-Yong;Song, Changhoon;Lee, Jeong-Woo;Cho, Woong;Suh, Tae Suk
    • Progress in Medical Physics
    • /
    • v.28 no.1
    • /
    • pp.16-21
    • /
    • 2017
  • This study assessed the feasibility of a dual-channel (DC) compound method for film dosimetry. The red channel (RC) is usually used to ensure dosimetric quality using a conventional fraction dose because the RC is more accurate at low doses within 3 Gy than is the green channel (GC). However, the RC is prone to rapid degradation of sensitivity at high doses, while degradation of the GC is slow. In this study, the DC compound method combining the RC and GC was explored as a means of providing accurate film dosimetry for high doses. The DC compound method was evaluated at various dose distributions using EBT3 film inserted in a solid-water phantom. Measurements with $10{\times}20cm^2$ radiation field and $60^{\circ}$ dynamic-wedge were done. Dose distributions acquired using the RC and GC were analyzed with root-mean-squares-error (RMSE) and gamma analyses. The DC compound method was used based on the RC after correcting the GC for high doses in the gamma analysis. The RC and GC produced comparatively more accurate RMSE values for low and high doses, respectively. Gamma passing rates with an acceptance criterion of 3%/3 mm revealed that the RC provided rapid reduction in the high dose region, while the GC displayed a gradual decrease. In the whole dose range, the DC compound method had the highest agreement (93%) compared with single channel method using either the RC (80%) or GC (85%). The findings indicate that the use of DC compound method is more appropriate in dosimetric quality assurance for radiotherapy using high doses.

A Power Control-Based MF-TDMA Resource Allocation Scheme for Next Generation Military Satellite Communication Systems (차기 군 위성통신망 체계에서 이기종 단말 운용을 고려한 전력제어 기반 MF-TDMA 자원할당 기법)

  • Woo, Soon;Park, Hyung-Won;Lee, Ho-Sub;Yoo, Youn-Sang;Jung, Byung-Gi
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.37C no.11
    • /
    • pp.1138-1147
    • /
    • 2012
  • In this paper, an efficient power control based MF-TDMA resource allocation scheme is proposed for next generation military satellite communication systems. The proposed scheme has the flexibility is used to support heterogeneous terminals with differ in transmission capabilities. The method can be divided into two parts : burst size calculation and burst structure determination. At first, we estimate the link budget taken into account a dynamic satellite link state variation. Then, applicable ACM level and burst size is chosen. In burst structure determination phase, we reorganize the burst structure in time-frequency domain by controlling limited power, bandwidth, time resources. In particular, we compensate the power spectral density among different terminals to integrate them in same transponder, Furthermore, we increase the packing efficiency by controlling the ACM level of the burst in applicable power spectral density range. Simulation results show that the method increase the spectral efficiency and burst packing efficiency. In addition, slot allocation rejection ratio is successfully reduced.