• Title/Summary/Keyword: Drying Technology

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Preparation of Prolonged Release Clarithromycin Microparticles for Oral Use and Their In Vitro Evaluation

  • Genc, Lutfi;Demirel, Muzeyyen;Yazan, Yasemin
    • Archives of Pharmacal Research
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    • v.29 no.10
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    • pp.921-927
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    • 2006
  • Prolonged release micro particles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, particle size distribution, X-ray diffraction, thermal behavior, active agent content and in vitro dissolution from the microparticles were performed. HPLC was used for the assay of clarithromycin and the assay method was validated. All the formulations obtained showed prolonged release when compared to pure clarithromycin. Microparticles prepared by spray-drying method had a slower release compared to those of casting drying method. Spray-drying method seems to be a more suitable method to prepare microparticles for prolongation in release.

Development of drying apparatus using 2-way condensation for marine products (2방식 응축을 이용한 수산물 건조 장치 개발)

  • Hwang, Jea-Ho
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.42 no.4
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    • pp.259-266
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    • 2006
  • In this study, the 2-way condensation system was designed applying air-to-air heat pump to dry a marine product such as squid in the winter. And to be made the drying apparatuses by this system, there are two kinds of type, A type, was set a compressor outside of the drying apparatus, B type, was set a compressor in the drying room. And then the variations of temperature in drying room were measured to compare the heating performance of the drying apparatuses between A type and B type at $-6.5^{\circ}C$, outdoor temperature. The temperature of the drying room for B type was increased to $36^{\circ}C$ but the temperature of the drying room for A type was not increased to $36^{\circ}C$, to be increased to $20^{\circ}C$.

A Study on the automation of external collector type solar-dehumidification drying of wood using a personal computer (개인용(個人用)컴퓨터를 이용(利用)한 외부집열판형(外部集熱板型) 제습태양열(除濕太陽熱) 목재건조(木材乾燥)의 자동화(自動化)에 관한 연구(硏究))

  • Lee, Hyoung-Woo
    • Journal of the Korean Wood Science and Technology
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    • v.20 no.2
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    • pp.23-30
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    • 1992
  • An experimental external external collector type, solar dehumidification dryer was retrofitted with a simple computer-based control system. Solar, solar-dehumidification, and air-drying of 3cm-thick douglas-fir were carried out to investigate the drying-conditions and characteristics of this system, and to analyze the energy efficiencies of each drying met hods in summer. The drying rate of solar-dehumidification was 12%/day, which was about 2 times and 3 times faster than that of solar-and air-drying, respectively. The amount of diurnal temperature fluctuation inside the solar-dryer was greatly reduced and the energy efficiency was enhanced from 25% to 60% by the dehumidifier.

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Far Infrared Rays Drying Characteristics of Tissue Cultured Mountain Ginseng Roots (산삼배양근의 원적외선 건조특성)

  • Li, H.;Kwang, T.H.;Ning, X.F.;Cho, S.C.;Han, C.S.
    • Journal of Biosystems Engineering
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    • v.34 no.3
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    • pp.175-182
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    • 2009
  • This study was conducted to investigate the drying characteristics of tissue cultured mountain ginseng roots. The far infrared rays dryer of a double blast system used for this experiment can control the drying parameters such as far infrared heater temperature and air velocity. The far infrared rays drying tests of tissue cultured mountain ginseng roots were performed at air velocity of 0.4, 0.6, 0.8 m/s, under drying air temperature of 50, 60, and $70^{circ}C$, respectively. The results were compared with one obtained by the heated air drying method. The drying characteristics such as drying rate, color, energy consumption, saponin components and antioxidant activities were analyzed. The results showed that the drying rate of far infrared rays drying was faster than that of heated air drying and due to high temperature of drying air and fast air velocity, the far infrared rays drying of double blast type was superior to the heated air drying. The value of the color difference for heated air drying was 10.11${\sim}$12.99 and that of far infrared rays drying was in the range of 7.05${\sim}$7.54, which was in the same drying condition, also energy consumption of far infrared rays drying was in the range of 3575${\sim}$6898 kJ/kg-water. At the same time, the antioxidant activities using far infrared rays drying were higher than those using heated air drying.

Quality Characteristics of Dried Squid (Todarodes Pacificus) by Cold Air Drying Process (냉풍건조공정을 이용한 마른오징어의 품질특성)

  • Hong, Joo-Heon;Bae, Dong-Ho;Lee, Won-Young
    • Korean Journal of Food Science and Technology
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    • v.38 no.5
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    • pp.635-641
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    • 2006
  • In an attempt to find ways of improving the quality and sanitary state of dried squid, this study compared artificial drying methods i.e. hot air drying and cold air drying with natural drying method. The drying rates of squid were in the order of hot air, cold air and natural drying. However, cold-air drying was slower than natural drying at $7^{\circ}C$. The drying rates increased with increasing drying temperature. When drying temperature was close to the dew point on a dehumidifier surface, which was the case with cold air drying at $7^{\circ}C$, the driving force for dehumidification was lower than under other drying conditions, which resulted in a lower drying rate. There were little color differences between the drying methods and temperature. Squid dried by cold air-drying had better mechanical texture and sensory qualities than with other drying methods. In addition, the cold air drying method maintained superior quality in terms of the contents of amino acids, taurine, EPA, DHA, other fatty acids and a low TBA value than the other drying methods.

Study on Kiln-Schedule Modification for Douglas Fir (미송(美松)의 열기건조(熱氣乾燥)스케쥴 개선(改善)에 관(關)한 연구(硏究))

  • Jung, Hee-Suk;Kozlik, Charles J.;Resch, Helmuth
    • Journal of the Korean Wood Science and Technology
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    • v.12 no.1
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    • pp.31-37
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    • 1984
  • For the modification of kiln drying schedule, relations between resistance to drying Rd and the moisture content or drying times were found for 4/4, 6/4 and 8/4 green Douglas fir heartwood by the mild drying schedule and the severe drying schedule until the average moisture content was about 10 percent. The results of this study were as follows. 1. Resistance to drying of thicker lumber was higher than that of thinner lumber and resistance to drying of three different thicknesses were negligible between the mild-and the severe drying schedule. The relationships between resistance to drying and two schedules or three thicknesses of lumber were $Rd_1=1.830{\times}10^5\;M^{-2.24}$ for 4/4 lumber by the mild drying schedule, $Rd_2=1.822{\times}10^5\;M^{-2.25}$ for 4/4 lumber by the severe drying schedule, $Rd_3=2.352{\times}10^5\;M^{-2.14}$ for 6/4 lumber by the mild drying schedule, $Rd_4=3.457{\times}10^5\;M^{-2.27}$ for 6/4 lumber by the severe drying schedule, $Rd_5=1.317{\times}10^6\;M^{-2.56}$ for 8/4 lumber by the mild drying schedule, $Rd_6=8.267{\times}10^5\;M^{-2.40}$ for 8/4 lumber by the severe drying schedule. 2. Thinner lumber exhibited lower level of moisture content and shorter drying time required at intersection point between the moisture content and resistance to drying as a function of drying time than those of thicker lumber. Drying time of mild drying was longer than that of severe drying and similar to the level of moisture content at intersection point.

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Effects of Drying Temperature on Internal Temperature, Drying Rate and Drying Defects for Japanese Larch in High-Temperature Drying (일본잎갈나무 정각재(正角材)의 고온건조(高溫乾燥) 온도(溫度)가 내부온도(內部溫度), 건조속도(乾燥速度) 및 건조결함(乾燥缺陷)에 미치는 영향(影響))

  • Lee, June-Ho;Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
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    • v.25 no.4
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    • pp.99-107
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    • 1997
  • This study was executed to test the possibility of replacement for domestic Japanese larch(Larix leptolepis) for hardwoods and to acquire the information about the effects of drying temperature on internal temperature, moisture content and drying defects. In high-temperature drying, internal temperature increased rapidly to boiling point, immediately after that point the internal temperature rising rate was reduced. In the case of drying at temperature of $125^{\circ}C$, internal temperature could reach at boiling point in a very short time. Moisture content in high-temperature drying showed constant drying rate period and first period of falling rate drying together in 4 hours since experiment begun. There was no strong correlation between initial moisture content and final moisture content. Average drying rate at $115^{\circ}C$, $120^{\circ}C$ and $125^{\circ}C$ was 1.42%/hr, 1.88%/hr and 2.02%/hr, respectively; the case of drying temperature of $125^{\circ}C$ showed most rapid drying rate. Drying rate of $125^{\circ}C$ was so rapid that it showed more severe shrinkage, bow, collapse, end check, and internal check development than in other drying conditions. The result of this study showed the strong possibility of high-temperature drying for Japanese larch, and to dry Japanese larch optimally, dry bulb temperature should not exceed $120^{\circ}C$.

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Study on Air-drying Characteristics of Taun Lumber and Air-dring Calendar(I) (타운 재목(材木)의 천연건조(天然乾燥) 특성(特性) 및 캘린더에 관한 연구(硏究)(I))

  • Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
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    • v.13 no.3
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    • pp.27-33
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    • 1985
  • Air-drying tests were carried out on green taun (Pometia pinnata f glabra) for 25-mm and 50-mm thickness to elucidate drying characteristics on air-drying rate, time and defects in spring and air-drying calendar. The results of this study were as follows: 1. The air-dried lumber for 25-mm thickness from an initial average moisture content (MC) of $58.3{\pm}3.5$ percent reached 30 percent MC in 17 days, 25 percent MC in 24 days, 20 percent MC in 38 days and 15 percent MC in 84 days. 2. The air-dried lumber for 50-mm thickness from an initial average MC of $59.6{\pm}5.0$ percent reached 30 percent MC in 39 days, 25 percent MC in 55 days and 20 percent MC in 84 days. 3. Air-drying calendar that could be useful in estimating drying times for each month developed by the use of climatological data for Suwon. Total number of effective air-drying days during a year were 243.5 days and the major determinant of the effect air-drying days was temperature. 4. The air-drying rates for 25-mm and 50-mm coated lumber were slight1y slower than those of uncoated lumber. The number and total length of both end checks and surface checks for end coated lumber were less severe than those of uncoated lumber.

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Drying Rate of Natural Paint Made by Rosin Using HORUS (HORUS를 이용한 천연페인트의 건조속도)

  • Choi, Jae-Hoon;Hwang, Hyeon-Deuk;Moon, Je-Ik;Kim, Hyun-Joong;Lee, Sun-Sang;Lee, Gwan-Hyung
    • Journal of the Korean Wood Science and Technology
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    • v.35 no.4
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    • pp.45-51
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    • 2007
  • To investigate the drying behaviors of the water-based natural coating made by rosin during drying, the mass transfer and optical change from speckle image and speckle rate were measured and the relationship between two analysis methods were investigated. At a linear scale, the speckle rate measured by HORUS related with the mass transfer of coating during drying, and the speckle rate at a log scale was included not only drying time, but also drying mechanism of coating during drying. Therefore, the HORUS was an available method to investigate the drying time and drying mechanism of coating during drying.

Effects of the Knife-Incising and Longitudinal Kerfing Treatment on High-Temperature Drying Characteristics of Red Pine Square Timber (배할 및 자상-인사이징 처리가 소나무 정각재의 고온건조 특성에 미치는 영향)

  • Lee, Chang-Jin;Lee, Nam-Ho;Oh, Seung-Won
    • Journal of the Korean Wood Science and Technology
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    • v.44 no.5
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    • pp.677-684
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    • 2016
  • This study was carried out to confirm the effects of the knife-incising and longitudinal kerfing treatment on high-temperature drying characteristics of red pine square timber with dimensions of thickness 15 cm. The range of final moisture content was investigated 5.6% to 7.5% after drying. The differences did not exist in the moisture content and distribution according to the pretreatment condition. In the case of longitudinal kerfing treatment, the surface check occurrence was reduced than the control. In addition, the twist had a tendency to decrease due to the longitudinal kerfing treatment. The knife-incising and longitudinal kerfing treatment were investigated to be ineffective on internal checks and drying shrinkage.