• 한국초지조사료학회지
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• 제14권4호
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• pp.316-323
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• 1994

In order to reduce the problems from the presence of rye crop residues in maize establishment and yield, and also to improve the growth, productivity and nutritive value of rye(Seca1e cereal L.). an experiment was canied out to determine the variety effect of rye on the forage production system and the eft'ect of seeding and harvesting dates on the production and quality of rye. 'This experiment was conducted at the forage testing field of S.N.U., Suweon, from September 1986 to May 1989. Heading date of an early maturing rye variety, Wintermore. was earlier 10 days than that of a late maturing rye variety, Kodiak. A 15-days delay in the seeding dates of early and late maturing varieties of rye tended to delay the heading dates of the rye varieties for 3 and 4 days, respectively. Dry matter and in vitro digestible dry matter yields were markedly increased with earlier seeding date. Before 20 April, the DM and IVDDM yeilds of an early maturing rye variety, Winterrnore. were higher than those of a late maturing rye variety, Kodiak. However, no such a trend was found between the early and late maturing varieties of rye after 27 April. Less than 35% of ADF was recorded until the harvesting dates of 13 and 27 p r i l for early and late maturing rye varieties, respectively, but less than 46% of NDF was maintained until the harvesting drtte of 13 April for botg varieties. Based on the results obtained from this experiment. it may be concluded that the most desirable forage production from corn-rye double cropping system is to advance the seeding time of rye toward the first 10 days of September as well as harvesting time toward the first heading stage with an early maturing rye variety.

• Journal of Gastric Cancer
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• 제15권2호
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• pp.77-86
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• 2015

Laparoscopic proximal gastrectomy (LPG) is theoretically a superior choice of minimally-invasive surgery and function-preserving surgery for the treatment of proximal early gastric cancer (EGC) over procedures such as laparoscopic total gastrectomy (LTG), open total gastrectomy (OTG) and open proximal gastrectomy (OPG). However, LPG and OPG are not popular surgical options due to three main concerns: the first, oncological safety; the second, functional benefits; and the third, anastomosis-related late complications (reflux symptoms and anastomotic stricture). Numerous recent studies have concluded that OPG and LPG present similar oncological safety profiles and improved functional benefits when compared with OTG and LTG. While OPG with modified esophagogastrostomy does not provide satisfactory results, OPG with modified esophagojejunostomy showed similar rates of anastomosis-related late complications when compared to OTG. At this stage, no standard reconstruction method post-LPG exists in the clinical setting. We recently showed that LPG with double tract reconstruction (DTR) is a superior choice over LTG for proximal EGC in terms of maintaining body weight and preventing anemia. However, as there is no definitive evidence in favor of LPG with DTR, a randomized clinical trial comparing LPG with DTR to LTG was recommended. This trial, the Korean Laparoscopic Gastrointestinal Surgery Study-05 (NCT01433861), is expected to assist surgeons in choice of surgical approach and strategy for patients with proximal EGC.

• Molecules and Cells
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• 제26권1호
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• pp.81-86
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• 2008

RNA interference (RNAi) was performed on several essential genes in the pinewood nematode Bursaphelenchus xylophilus, which causes pine wilt disease. Double-stranded RNA (dsRNA) was delivered to larvae or adult worms by soaking, electroporation, or microinjection. Soaking and electroporation of L2-L3 stage worms in solutions containing dsRNA for essential genes induced over 25% lethality after 5 days, and gene-specific phenotypes were observed. This lethality agreed with significant reductions of the targeted transcripts, as assayed by reverse-transcription coupled with real time PCR. Microinjection was the most efficient route as measured by the hatching rate of F1 embryos, which was reduced by 46%. When adult worms were soaked in dsRNA, lethality was induced in the F1 larvae, revealing the persistence of knockdown phenotypes. The penetrance of the RNAi phenotypes for essential genes was relatively low but consistent, indicating that RNAi should be useful for studying the in vivo functions of B. xylophilus gene products.

• 한국전자파학회논문지
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• 제11권1호
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• pp.84-92
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• 2000

2.4 GHz 대역 WLL 단말기용 GaAs MESFET MMIC 송신기를 설계하고 제작하였다. 설계된 송신기는 이중 평형 능동형 혼합기와 전압 부궤환 구조를 갖는 2단 구동증폭기로 구성하였다. 특히, 한 쌍의 소스 접지-게이트 접지(Common-Source. Common -Gate: CSCG) 구조를 사용하여 IF 입력 선호의 비대칭성으로 인한 동작영역 감소를 보상하였다. 또한 MESFET의 단자간 위상 특성을 이용하여 국부 발진기(La) 신호의 누설 전력을 억제 하였다. 제작된 칩의 크기는 $0.75\times1.75 mm^2$이었고 측정 결과 2.7 V. 55.2 mA에서 386 dB의 변환이득. 11.6 dBm 의 출력$P_{idB}$ 구동증폭기의 RF 출력 -5dBm에서 - 31.5 dBc의 IMD3의 특성을 얻었다. 따라서 제작된 송신기는 WLL 단말기에 적용 가능하다.

• Journal of Gastric Cancer
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• 제11권4호
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• pp.219-224
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• 2011

Purpose: The Roux en Y method has rarely been performed due to longer operation time and high risk of complication, despite several merits including prevention of bile reflux. We conducted a retrospective review of the result of Roux en Y reconstruction using two circular staplers after subtotal gastrectomy. Materials and Methods: From December 2008 to May 2009, a total of 26 patients underwent Roux en Y reconstruction using two circular staplers after subtotal gastrectomy, and seventy-two patients underwent Billroth-I reconstruction. Roux en Y anastomosis was performed using two circular staplers without hand sewing anastomosis. We compared clinicopathologic features and surgical outcomes between the two groups. All patients underwent gastrofiberscopy between six and twelve months after surgery to compare the bile reflux. Results: No significant differences in clinicopathologic findings were observed between the two groups, except for the rate of minimal invasive surgery (P=0.004) and cancer stage (P=0.002). No differences in the rate of morbidity (P=0.353) and admission duration (P=0.391) were observed between the two groups. Gastrofiberscopic findings showed a significant reduction of bile reflux in the remnant stomach in the Roux en Y group (P=0.019). Conclusions: When compared with Billroth-I reconstruction, Roux en Y reconstruction using the double stapler technique was found to reduce bile reflux in the remnant stomach without increasing postoperative morbidity. Based on these results, we planned to begin a randomized controlled clinical trial for comparison of Roux en Y reconstruction using this method with Billroth-I anastomosis.

• Structural Engineering and Mechanics
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• 제56권5호
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• pp.813-833
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• 2015

Spherical reticulated shells are widely applied in structural engineering due to their good bearing capability and attractive appearance. Parametric modeling of spherical reticulated shells is the basis of internal analysis and optimization design. In the present study, generation methods of nodes and the corresponding connection methods of rod elements are proposed. Modeling programs are compiled by adopting the ANSYS Parametric Design Language (APDL). A shape optimization method based on the two-stage algorithm is presented, and the corresponding optimization program is compiled in FORTRAN environment. Shape optimization is carried out based on the objective function of the minimum total steel consumption and the restriction condition of strength, stiffness, slenderness ratio, stability. The shape optimization of four typical Schwedler spherical reticulated shells is calculated with the span of 30 m~80 m and rise to span ratio of 1/7~1/2. Compared with the shape optimization results, the variation rules of total steel consumption along with the span and rise to span ratio are discussed. The results show that: (1) The left and right rod-Schwedler spherical reticulated shell is the most optimized and should be preferentially adopted in structural engineering. (2) The left diagonal rod-Schwedler spherical reticulated shell is second only to left and right rod regarding the mechanical behavior and optimized results. It can be applied to medium and small-span structures. (3) Double slash rod-Schwedler spherical reticulated shell is advantageous in mechanical behavior but with the largest total weight. Thus, this type can be used in large-span structures as far as possible. (4) The mechanical performance of no latitudinal rod-Schwedler spherical reticulated shell is the worst and with the second largest weight. Thus, this spherical reticulated shell should not be adopted generally in engineering.

• 대한전자공학회논문지SD
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• 제38권1호
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• pp.69-78
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• 2001

본 논문은 휴대용 고속 페이징 시스템을 위한 FLEXTM 프로토콜 신호 처리기의 설계 및 FPGA 구현에 관한 것이다. 본 논문에서는 A/D 변환기의 입력 단에서 수신된 interleaved 4-level 비트 심볼 데이터의 동기를 위한 심볼 동기 알고리듬과 (31,21)BCH 부호에 대해 실시간 2중 오류정정이 가능한 개선된 복호 알고리듬을 제안한다. 설계된 프로토콜 신호처리기는 6개의 기능 모듈로 구성되어 있으며, 각 모듈은 VHDL(VHSIC Hardware Description Language)로 모델링을 행하였다. 제안된 프로토콜 신호기는 Axil-320 워크스테이션 상에서 Synopsys/sup TM/툴을 이용하여 기능 시뮬레이션 및 논리합성(Altera 10K 라이브러리 이용)을 수행하였다. 논리합성 결과 전체 셀의 수는 약 2,631이었다 또한, 설계된 FPGA 칩의 설계검증을 위하여 Altera MAX+ PLUS Ⅱ 상에서 타이밍 시뮬레이션을 수행하였다. PCB 상에서 testbed를 구축한 후, Logic Analyzer를 이용하여 제작된 FPGA 칩의 동작상태를 확인하였고, 실험을 통하여 제작된 칩이 정확히 동작함을 확인하였다.

• Clinical and Experimental Reproductive Medicine
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• 제30권4호
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• pp.299-307
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• 2003

Objectives: The present study was conducted to evaluate the mobile transposon-like element, clone MTi7 (MTi7) expression in the mouse ovary and to determine its role(s) in the mouse oocytes by RNA interference (RNAi). Methods: MTi7 mRNA expression was localized by in situ hybridization in day5 and adult ovaries. Double stranded RNA (dsRNA) was prepared for c-mos, a gene with known function as control, and the MTi7. Each dsRNA was microinjected into the germinal vesicle (GV) stage oocytes then oocyte maturation and intracellular changes were evaluated. Results: In situ hybridization analysis revealed that MTi7 mRNA localized to the oocyte cytoplasm from primordial to preovulatory follicles. After dsRNA injection, we found 43-54% GV arrest of microinjected GV oocytes with 68%-90% decrease in targeted c-mos or MTi7 mRNA. Conclusions: This is the first report of the oocyte-specific expression of the MTi7 mRNA. From results of RNAi for MTi7, we concluded that the MTi7 is involved in the germinal vesicle breakdown in GV oocytes, and MTi7 may be implicated with c-mos for its function. We report here that RNAi provides an outstanding approach to study the function of a gene with unknown functions.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권3호
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• pp.151-159
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• 2018

Background: The pain involved in orthodontic treatments may involve inflammatory processes. This study evaluated the effect of using a naproxen patch for pain reduction in the separating stage of fixed orthodontic treatment. Methods: In this double-blind, randomized, controlled clinical trial of 35 orthodontic patients (age: 14-19 years) who had pain during separator placement, each patient randomly placed naproxen and placebo patches in the first permanent molar region, in opposite quadrants of the same jaw. Patches were replaced every 8 hours until 3 days after separator placement. Patients recorded their pain perception at 2, 6, and 24 hours, and on days 2 (6 PM), 3 (10 AM and 6 PM), and 7 (10 AM and 6 PM), using a visual analog scale. Mean pain scores were compared for the two patches, and effects of sex and age thereon determined. Results: Data from 29 patients (21 girls, eight boys) were analyzed. Mean pain values decreased over time for both patches (P < 0.001). Recorded pain did not differ significantly between the sexes (P = 0.059) or between those aged <16 and those ${\geq}16years$ (P = 0.106). Mean pain recorded with naproxen patches was statistically significantly less than that with placebo patches at all time points (P = 0.004). Conclusion: The naproxen patch was more efficient than the placebo patch for reducing pain at all time points. The highest pain score was recorded at 6 hours, and the least pain was recorded at the $7^{th}$ day after separator placement.

• 한국연소학회지
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• 제19권1호
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• pp.17-28
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• 2014

In this study, the laminar burning velocity of syngas fuel($H_2/CO$) and flame structure with various hydrogen contents were studied using both experimental measurements and detailed kinetic analysis. The laminar burning velocities were measured by the angle method of Bunsen flame configuration and the numerical calculations including chemical kinetic analysis were made using CHEMKIN Package with USC-Mech II. A wide range of syngas mixture compositions such as $H_2$ : CO = 10 : 90, 25 : 75, 50 : 50, 75:25 and equivalence ratios from lean condition of 0.5 to rich condition of 5.0 have been considered. The experimental results of burning velocity were in good agreement with previous other research data and numerical simulation. Also, it was shown that the experimental measurements of laminar burning velocity linearly increased with the increment of $H_2$ content although the burning velocity of hydrogen is faster than the carbon monoxide above 10 times. This phenomenon is attributed to the rapid production of hydrogen related radicals such as H radical at the early stage of combustion, which is confirmed the linear increase of radical concentrations on kinetic analysis. Particular concerns in this study are the characteristics of burning velocity and flame structure different from lean condition for rich condition. The decrease of OH radicals and double peaks are observed with $H_2$ content in rich condition once $H_2$ fraction exceeds over threshold.