• 동의생리병리학회지
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• 제17권6호
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• pp.1533-1537
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• 2003

This double-blind randomized clinical trial was performed to evaluate the anti-anxiety, anti-stress effect of a modified formula WS-01 consisted with several herbs(Jujubae Fructus. Longanae Arillus. Poria Cocos) and germinated rice. The extract of the formula was administered (p.o) to 24 students and placebo was to 23 students for 4 weeks. STAI-KYZ(Hahn. Hakjisa), ABR2000(Meridian, Korea), CBC, LFT, U/A were checked before and after the administration period. There was no difference between the STAI score of WS-01 and that of placebo group in first test. But the STAI state anxiety score was 5.33±7.33 reduced in WS-01 group and it was 0.52±6.42 increased in placebo group in second test. this result was significant stastically. 10 students in WS-01 group showed improving result, but only 1 student in placebo group showed improving result of ABR2000 test. The result of ABR2000 was analyzed with curve 2, Regulation 2, and graph 1,2,3, because those reflect central nerve system and stressful condition of the body. There was no significant result in first and second CBC, LFT, Urine test. The results of this clinical study suggest that WS-01 has anti-anxiety, anti-stress effect, and it could be applied to various conditions or disorders related with anxiety and stress.

• The Plant Pathology Journal
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• 제22권1호
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• pp.68-74
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• 2006

A new virus with a dsRNA genome was isolated and characterized from the Suhan-:neutari strain (ASI 2504) of Pleurotus ostreatus, which was characterized as long and slightly bent with small caps on the stipe of fruit body. Thirty nm isometric viruses with three dsRNA segments (approximately 2.0, 1.84 and 1.82 kb in sizes) were isolated by ultracentrifugation in sucrose gradients. Western analysis of protein extracted purified viruses with anti-virus polyclonal antibody confirmed that viruses have two specific proteins (36 and 68 kDa). Computer analysis of 2.0 kb segment shows that high. sequence identity with RNA-dependent RNA polymerase (RdRp) of partitiviruses, respectively. When compared to other dsRNA mycoviruses in a phylogenetic analysis, OMDV was most related to Pleurotus ostreatus virus 1.

• 환경위생공학
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• 제20권1호
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• pp.55-63
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• 2005

Ground water samples of 275 were collected from Gapyeong county which it contained six-eup and myeon and analyzed for 12 mineral inorganics extending from March to October in 2004. Among the inorganics, Calcium, Magnesium, Sodium, Potassium, Copper and Zinc had more than $70\%$ of detection frequencies, which coincided with essential inorganics required by the human body. The average values of inorganic contents by sampling sites were insignificant. Fluorine contents of 8 samples, $2.9\%$ of 275 samples, exceeded KDWR, and it was considered to be affected by a base rock being made up granite and gneiss because there were not polluting sources around. It is necessary to find out relation between geological characteristics and mineral inorganics in ground water through the further investigation. Compared to noted concentrations of bottled water, inorganic minerals including Calcium, magnesium, Sodium and Potassium related to taste were fluent double in target samples and those average concentrations were 14.80, 3.80, 7.60, and $2.31\cal{mg/L}$ respectively.

• 한국산학기술학회논문지
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• 제11권9호
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• pp.3119-3124
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• 2010

본 논문은 엔진 베어링에서 크랭크샤프트의 경사도를 고려했을 때와 고려하지 않았을 때 유막 동적거동을 컴퓨터 시뮬레이션을 이용하여 해석하였다. 본 해석은 탄성유체윤활 이론을 바탕으로 하여 최소유막의 동적특성을 수치적으로 해석하였다. 유막설계에 매우 중요한 인자인 크랭크샤프트 경사도를 고려하기 위하여 크랭크샤프트와 엔진베어링을 탄성체로 모델링 하였다. 유막거동해석을 위한 경계조건으로는 엔진 베어링에서 발생하는 비선형 구속력과 굽힘 모멘트를 고려하였고 이에 따른 크랭크샤프트의 경사도 영향을 고려함으로써 좀 더 실제 현상과 유사한 모델링을 수행하였다. 해석결과 엔진 베어링의 성능에 가장 큰 영향을 미치는 최소유막두께가 크랭크샤프트의 경사도를 고려하지 않았을 때보다 고려하였을 때 16%에서 24%정도 감소하는 것을 알 수 있었다. 또한, 해석결과에서와 같이 크랭크샤프트 경사도 증가는 최소유막두께의 감소를 유발하고 이에 따른 베어링 파손을 예측할 수 있었다. 따라서 본 논문의 해석결과가 자동차 엔진 베어링 설계 시 매우 유용한 자료로 사용될 것으로 사료된다.

• 전력전자학회논문지
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• 제7권6호
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• pp.524-530
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• 2002

일상 생활에서 반사적인 자세 조절은 정전기관, 시각, 고유수용체 등의 감수체에 의한 구심성 신호가 정전 신경핵에 전달되어 안구운동이나 골격근의 수축을 유발하여 이루어진다. 자세조절기능의 부조화는 오심, 구토, 현기증 등을 초래하여 삶의 의욕을 상실하게 만든다. 본 연구의 목적은 정전기관의 반규관과 이석기관을 선별적으로 자극하기 위한 탈수직축 회전자극 시스템과 수평, 수직, 3D 환경에서 시각자극을 할 수 있는 시운동자극시스템을 개발하여 인간의 자세조절 기능을 평가 하는데 있다. 탈수직축 회전자극 시스템은 편안한 의자와 DC 서보모터로 구동되는 기울임 테이블로 구성되고 PMSM에 의해 제어된다. 그리고 속도 궤환 루프와 위치 궤환 루프를 포함하는 이중 피드백 루프가 서보 제어되는 회전자극시스템에 적용된다. HMD를 이용하여 수평, 수직, 3D 시각자극패턴을 구현 하였고 OKN 자극을 위한 무선시스템과 전기안진 기록계를 이용하여 안구운동을 기록하였다. 이득, 위상, 대칭성은 정전 자극과 시각 자극에 의해 유발되는 안구운동의 분석으로부터 얻어진다.

• 한국의류산업학회지
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• 제19권5호
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• pp.635-645
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• 2017

The industry of character toys is increasing and new characters are constantly being developed. However, the development of 2D cover patterns for toys is time-consuming due to frequent pattern modifications made through trial and error. Studies are now underway to obtain 2D clothing patterns from 3D body data, however, little research has been done on 2D pattern of character toys. This study suggests efficient guidelines to develop 2D cover patterns with a reasonable accuracy and processing time. Two 3D models of a dog and rabbit were used to develop 2D cover patterns. Independent variables of this study are set as 3 levels of triangle area (small, medium, and large) that influence the efficacy of 3D and 2D pattern development. The determination of the appropriate triangular area was based on the area and shape change of the 2D pattern. A medium or large triangle area was shown to be suitable for a character dog with a smooth curved surface. However, the appropriate triangle area was small if the characteristics of the curved surface are complicated as in the case of rabbit. The head of a dog (a double-curved surface) and the curved forepaw of a rabbit (a triangular area) should be small when the characteristics of the curved surface (such as the hind leg of a rabbit having a large convex surface and a small surface area) are complicated. Grouping by 3D surface characteristics could be a suitable guideline for the triangle area selection.

• Parasites, Hosts and Diseases
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• 제22권1호
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• pp.127-134
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• 1984

As a series of studies to clarify clonorchicidal substances in body surface mucus of some freshwater fishes, the substance in the epidermal mucus of Cyprinus carpio was isolated by silica gel column and thin layer chromatography and analysed for its chemical nature. Wormicidal trial was done in vitro, and the results obtained are summarized as follows: The mucus was extracted by ethyl ether and separated into 4 fractions by column chromatography using benzene as solvent. The second fraction with yellowish red colour among them showed the strongest clonorchicidal effect. The yellowish red fraction obtained by column chromatography was then fractionated into 6 spots by thin layer chromatography with petrol/ etherjchloroform (30/70, v/v), and the Rf. 0.714 spot among the 6 spots showed the strongest effect. The Rf. 0.714 spot was further fractionated into 6 spots by thin layer chromatography with benzene/acetone (90/10, vlv), and the Rf. 0.800 spot among the later 6 spots revealed the strongest effect. The Rf. 0.800 spot was chromatographed on column with benzene and 2 fractions were obtained. The second fraction of light brown colour represented the final purified fraction. By these Purification Procedures, clonorchicidal substance was Purified 15-fold with 0.035 yield from the mucus of C. carpio, and 10mg of the final fraction killed the cercaria in 26 min, the metacercaria in 115 min, and the adult in 443 min. Infra red and nuclear magnetic resonance spectrometric analysis of the purified substance revealed that the substance belongs to an ethyl ester of unsaturated fatty acid with 2 double bonds, 15 methylene groups and 1 methyl group.

• Annals of Clinical Neurophysiology
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• 제19권2호
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• pp.118-124
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• 2017

Electroencephalography (EEG) is frequently used to assist the diagnosis of brain death. However, to date there have been no guidelines in terms of EEG criteria for determining brain death in Korea, despite EEG being mandatory. The purpose of this review is to provide an update on the evidence and controversies with regarding to the utilization of EEG for determining brain death and to serve as a cornerstone for the development of future guidelines. To determine brain death, electrocerebral inactivity (ECI) should be demonstrated on EEG at a sensitivity of $2{\mu}V/mm$ using double-distance electrodes spaced 10 centimeters or more apart from each other for at least 30 minutes, with intense somatosensory or audiovisual stimuli. ECI should be also verified by checking the integrity of the system. Additional monitoring is needed if extracerebral potentials cannot be eliminated. Interpreting EEG at high sensitivities, which is required for the diagnosis of brain death, can pose a diagnostic challenge. Furthermore, EEG is affected by physiologic variables and drugs. However, no consensus exists as to the minimal requirements for blood pressure, oxygen saturation, and body temperature during the EEG recording itself, the minimal time for observation after the brain injury or rewarming from hypothermia, and how to determine brain death when the findings of ECI is equivocal. Therefore, there is a strong need to establish detailed guidelines for performing EEG to determine brain death.

• 한국수산과학회지
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• 제16권4호
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• pp.395-400
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• 1983

1982년 11월 18일 부터 25일 사이에 해운대 동백섬에 위치한 부산수산대학 해양과학연구소 앞 연안에서 주낚으로 채집된 성숙한 노래미를 이용하여 실험실내에서 인공수정에 의한 난발생과정과 부화자어에 관하여 관찰한 결과를 요약하면 다음과 같다. 난은 구형이며 침성점착난으로 난경은 $1.92{\sim}2.14mm$로 짙은 황색의 유구가 무수히 존재한다. 실내수온 $11.8{\sim}17.9^{\circ}C$(평균 $14.2^{\circ}C$)에서 수정후 463시간만에 부화하였다. 부화직후의 자어는 전장 $6.55{\sim}8.2mm$이며 근절수 12+36=48. 난황의 전단에 큰 유구가 하나 있다. 부화후 3일째의 전장 7.8mm의 자어는 꼬리부분의 $13{\sim}19$번째의 근절부분에 $4{\sim}5$개의 흑색소포 나타난다.

• Nutrition Research and Practice
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• 제10권4호
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• pp.418-423
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• 2016

BACKGROUND/OBJECTIVES: Spirulina, a blue-green alga, is widely produced and commercialized as a dietary supplement with bio- and immune-modulatory functions. We have previously shown that spirulina had favorable effects on lipid profiles, immune functions, and antioxidant capacity in healthy Korean elderly. Despite favorable effect of spirulina supplementation, some sub-populations have shown a poor response to supplementation. Obesity is a factor related to poor-response. Therefore, the purpose of this study was to determine the immuno-modulation, antioxidant capacity, and lipid-lowering effect of spirulina in obese and non-obese Korean elderly. SUBJECTS/METHODS: The subjects were 78 elderly aged 60-87 years. In a randomized double blind, placebo-controlled study, subjects were fed either placebo or spirulina daily, at 8 g for 12 weeks. Subjects were divided into the non-obese group and the obese group based on body mass index (BMI) criteria for Asians suggested by the International Obesity Task Force: $BMI<25kg/m^2$ (non-obese) and $BMI{\geq}25kg/m^2$ (obese). RESULTS: In the non-obese group, spirulina supplementation showed a significant lowering effect on plasma concentration of total cholesterol and LDL-cholesterol, a significant increase in interleukin (IL)-2 concentration (P < 0.01) and a significant increment (P < 0.05) in IL-2/IL-6 ratio, and a significant increase in total antioxidant status level and a significant decrease in thiobarbituric acid reactive substances level. However, these effects were not observed in the obese group. CONCLUSION: These results demonstrated that blood lipid lowering and immune and antioxidant improving response for spirulina supplement was affected by obesity in Korean elderly.