• Title/Summary/Keyword: Dot Product

Search Result 49, Processing Time 0.023 seconds

Expression of Human Lactoferricin in HC11 Cells (HC11 세포에서 인체 락토페리신의 발현)

  • Nam, Myoung-Soo
    • Korean Journal of Agricultural Science
    • /
    • v.28 no.2
    • /
    • pp.92-98
    • /
    • 2001
  • Lactofenicin is an antibacterial peptide fragment (about 5 kD) derived from lactoferrin (80 kD) that displays the various biological functions. The production of a human lactoferricin (Lactoferricin H) in mouse HC11 mammary epithelial cells was achieved by placing its cDNA under the control of the bovine ${\beta}$-casein gene. To express lactoferricin H in this cell culture system, constructed a hybride-splice signal consisting of bovine ${\beta}$-casein intron I and rabbit ${\beta}$-globin intron II, and a DNA fragment spanning intron 8 of the bovine ${\beta}$-casein gene. Expression of lactofenicin H from this expression vector was identified by RT-PCR, northern and dot blot analysis. RT-PCR using total RNA of HC11 cells transfected with pBL1-cin expression vector yielded a product identified as having a size of the 150bp. Northern blot analysis was identified about 2.3 kb. In dot blot analysis, recombinant lactofenicin H was recognized with anti-human lactofrrnin polyclonal antibody.

  • PDF

Identification Performance of Low-Molecular Compounds by Searching Tandem Mass Spectral Libraries with Simple Peak Matching

  • Milman, Boris L.;Zhurkovich, Inna K.
    • Mass Spectrometry Letters
    • /
    • v.9 no.3
    • /
    • pp.73-76
    • /
    • 2018
  • The number of matched peaks (NMP) is estimated as the spectral similarity measure in tandem mass spectral library searches of small molecules. In the high resolution mode, NMP provides the same reliable identification as in the case of a common dot-product function. Corresponding true positive rates are ($94{\pm}3$) % and ($96{\pm}3$) %, respectively.

Analysis of the Time-dependent Optical Properties of the Entire LCD Panel

  • Lee, Do-Young;Yoo, Ki-Taek;Park, Cheol-Woo;Lee, Kyung-Ho
    • Journal of Information Display
    • /
    • v.10 no.2
    • /
    • pp.62-67
    • /
    • 2009
  • To understand panel driving more accurately, the optical properties and their distributions in the LCD panel itself, excluding the backlight, were investigated by measuring the transmittance of a one-dot pixel as a function of time. First, the behavior of time-dependent transmittance was analyzed, and it was found that the off-state TFT was not in a steady state but in a transient state during the holding period. Second, the time average, max, min, and range values of the transmittance curves were examined by varying the common voltage level and gray scale. Third, the analysis of such properties was expanded to cover those of the entire panel in all the gray scales. Lastly, the relationship between their properties and distributions was also investigated along with the contour plots.

User Bias Drift Social Recommendation Algorithm based on Metric Learning

  • Zhao, Jianli;Li, Tingting;Yang, Shangcheng;Li, Hao;Chai, Baobao
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.16 no.12
    • /
    • pp.3798-3814
    • /
    • 2022
  • Social recommendation algorithm can alleviate data sparsity and cold start problems in recommendation system by integrated social information. Among them, matrix-based decomposition algorithms are the most widely used and studied. Such algorithms use dot product operations to calculate the similarity between users and items, which ignores user's potential preferences, reduces algorithms' recommendation accuracy. This deficiency can be avoided by a metric learning-based social recommendation algorithm, which learns the distance between user embedding vectors and item embedding vectors instead of vector dot-product operations. However, previous works provide no theoretical explanation for its plausibility. Moreover, most works focus on the indirect impact of social friends on user's preferences, ignoring the direct impact on user's rating preferences, which is the influence of user rating preferences. To solve these problems, this study proposes a user bias drift social recommendation algorithm based on metric learning (BDML). The main work of this paper is as follows: (1) the process of introducing metric learning in the social recommendation scenario is introduced in the form of equations, and explained the reason why metric learning can replace the click operation; (2) a new user bias is constructed to simultaneously model the impact of social relationships on user's ratings preferences and user's preferences; Experimental results on two datasets show that the BDML algorithm proposed in this study has better recommendation accuracy compared with other comparison algorithms, and will be able to guarantee the recommendation effect in a more sparse dataset.

Creativity evaluation of design concepts using AHP (AHP를 활용한 디자인 콘셉트의 창의성 평가에 관한 연구)

  • Seo, ChangWon;Park, Young T.
    • Journal of Korean Society for Quality Management
    • /
    • v.44 no.4
    • /
    • pp.855-867
    • /
    • 2016
  • Purpose: Evaluation of the creativity level of design concepts. Methods: 14 winners of design concepts area of the 2015 Red dot Award are used to evaluate the creativity level of design concepts. Among the 14 winners, one is the highest award (; luminary) winner, 4 are the second highest award(; best of the best) winners, and the remaining 9 are winners. AHP model was developed to evaluate the creativity levels of design concepts, and applied to the 14 winners of the reddot award. Results: Originality and practicality have been used to evaluate creativity level of new product ideas in the previous study. In this study, it is identified that originality is composed of innovativeness and topicality, and practicality is composed of utility and realizability. The design concepts which won higher level awards have higher level of originality. Among the two dimensions of originality, topicality has more significant relationship than innovativeness. Conclusion: The design concepts with higher level of originality, especially higher level of topicality, have a fair chance to be recognized as creative. It is notable that higher level of originality does not guarantee higher profit. According to the previous studies on the commercial success of new products, practicality is more important than originality.

ESTIMATE FOR BILINEAR CALDERÓN-ZYGMUND OPERATOR AND ITS COMMUTATOR ON PRODUCT OF VARIABLE EXPONENT SPACES

  • Guanghui, Lu;Shuangping, Tao
    • Bulletin of the Korean Mathematical Society
    • /
    • v.59 no.6
    • /
    • pp.1471-1493
    • /
    • 2022
  • The goal of this paper is to establish the boundedness of bilinear Calderón-Zygmund operator BT and its commutator [b1, b2, BT] which is generated by b1, b2 ∈ BMO(ℝn) (or ${\dot{\Lambda}}_{\alpha}$(ℝn)) and the BT on generalized variable exponent Morrey spaces 𝓛p(·),𝜑(ℝn). Under assumption that the functions 𝜑1 and 𝜑2 satisfy certain conditions, the authors proved that the BT is bounded from product of spaces 𝓛p1(·),𝜑1(ℝn)×𝓛p2(·),𝜑2(ℝn) into space 𝓛p(·),𝜑(ℝn). Furthermore, the boundedness of commutator [b1, b2, BT] on spaces Lp(·)(ℝn) and on spaces 𝓛p(·),𝜑(ℝn) is also established.

Application of Vector Scalar Product to Solve the Kinematic Equations in the Earth's Gravitational Field (지구 중력장 내에서 성립하는 운동 상태 방정식의 해를 구하기 위한 벡터의 스칼라 프로덕트 응용)

  • Um, Kee-Hong
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.17 no.6
    • /
    • pp.217-222
    • /
    • 2017
  • Any object located in the earth's gravitational field experiences a force in the direction of the center of the earth. In order to describe the motion of objects in the field, the solutions to a system of simultaneous vector kinematic equations need to be obtained. In the analysis of freely-falling objects, the reference direction +y is usually defined to be the downward direction. In the analysis of the motion of objects thrown upward, the reference direction +y is usually defined to be the upward direction. In the analysis of the motion of objects thrown downward, the reference direction +y is usually defined to be the downward direction. In this paper, we show that the choice of reference axis in either upward or direction gives the same results by adopting a scalar product of two vectors in solving the vector kinematic equations. It is rare to find other examples of using a scalar product of two vectors in solving vector kinematic equations describing the motion of objects. An application of this study is that we can arbitrarily choose the reference direction for objects moving in a horizontal direction, including projectile motions.

Transfer of Foreign Gene into Mud Loach, Misgurnus mizolepis I . Availability of the lacZ as a reporter gene for producing transgenic mud loach (미꾸라지, Misgurnus mizozepis에 외래 유전자 이식 I. lacZ의 reporter 유전자로서의 유용성 검토)

  • KIM Dong Soo;NAM Yoon Kwon
    • Journal of Aquaculture
    • /
    • v.7 no.1
    • /
    • pp.41-54
    • /
    • 1994
  • In order to evaluate the availability of lacZ as a reporter gene for producing transgenic mud loach, foreign DNA, bacterial \beta-galactosidase$ gene (lacZ) was microinjected into mud loach eggs and its insertion and expression were examined. X-gal based histochemical assay, fluorimetric analysis of \beta-galactosidase$ with 4-methylumbelliferyl-$\beta$-D-galactoside (MUG) and molecular biological examination using polymerase chain reaction (PCR), dot blot, southern blot and sequence analysis of PCR products were carried out to analyze both microinjected group and non-injected controls. The results are disccussed in this paper.

  • PDF

Global and Local Views of the Hilbert Space Associated to Gaussian Kernel

  • Huh, Myung-Hoe
    • Communications for Statistical Applications and Methods
    • /
    • v.21 no.4
    • /
    • pp.317-325
    • /
    • 2014
  • Consider a nonlinear transform ${\Phi}(x)$ of x in $\mathbb{R}^p$ to Hilbert space H and assume that the dot product between ${\Phi}(x)$ and ${\Phi}(x^{\prime})$ in H is given by < ${\Phi}(x)$, ${\Phi}(x^{\prime})$ >= K(x, x'). The aim of this paper is to propose a mathematical technique to take screen shots of the multivariate dataset mapped to Hilbert space H, particularly suited to Gaussian kernel $K({\cdot},{\cdot})$, which is defined by $K(x,x^{\prime})={\exp}(-{\sigma}{\parallel}x-x^{\prime}{\parallel}^2)$, ${\sigma}$ > 0. Several numerical examples are given.

Analysis on LGP with Multi-Side-Lamp (다변 광원 도광판에 대한 연구)

  • Park Jong-Ryul;Sah Jong-Youb
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.29 no.3 s.234
    • /
    • pp.361-368
    • /
    • 2005
  • LGP(Light-Guide Panel) of LCD backlight is one of the major componets which affect on the product quality of LCD. The LGP with multi-side lamp has been analized for pattern design with the uniform distribution of brightness. When given the uniform distribution of brightness as target, the distribution of dot pattern has been designed for superposed distributions of brightness for each lamp. Multi-side lamp has been tested for various types such as ㄴ-, ㄷ-, and ㅁ -shapes. The present study enhances the possibility of LGP with multi-side lamp by showing the pricise control of brightness distribution.