• 대한수의학회지
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• 제7권2호
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• pp.51-55
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• 1967

The mammary excretion of suphamethomidine after intravenous and/or oral administration was investigated in cow. The results show that sulphamethomidine is bound to plasma proteins to a great extent (80~90%). Ay a dosage of 60 mg./kg. maximal concenration in plasma of this sulphonamide was reached 7-10 hours after oral dosing. The sulphonamide concentration in plasma slowly declined after both oral and intravenous administration (fig. 1, 2, and 3) The concentration of sulphonamide in milk was very low and the excretion was completed in 7 days after a single oral dose and 5 days after intravenous injection while in the case of blood plasma it was 11 and 7 days, respectively. In addition, the renal excretion of sulphamethomidine was investigated while under continuous intravenous intravenous infusion. The excretion ratios varies according to self depression (table. 1). Blockade of the tubular secretion with diodone lowered the excretion of sulphamethomidine. It is concluded that the renal excretion of sulphamethomidine in cows occurs by filtration by slight tubular secretion and also by a high rate of back diffusion.

• 상하수도학회지
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• 제18권2호
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• pp.247-253
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• 2004

Major species of Lake Deganuma has varied depending on the season. Namely, there are Micractinium pusillum, chlorella., Scenedesmus sp. shown up in spring season, Microcystis aeruginosa, Microcystis wesenbergii, Anabena spiroides in summer and autumn season and Cyclostephanos invisitatus, Diatoma in winter season in the Lake. As the number of plankton increased, the zeta potential on their surface of them decreased. For this reason, they were dispersed in the lake though the population increased. Zeta potential of M. aeruginosa showed -20mV when their outer size got smaller. As for coagulant dosing in DAF, large amount of coagulant was effective to get lots of sludge during water treatment.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.274-274
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• 2013

We fabricate encapsulation-layer of OLED panel from organic-inorganic hybrid thin film by atomic layer deposition (ALD) molecular layer deposition (MLD) using Al2O3 as ALD process and Adipoyl Chloride (AC) and 1,4-Butanediamine as MLD process. Ellipsometry was employed to verify self-limiting reaction of MLD. Linear relationship between number of cycle and thickness was obtained. By such investigation, we found that desirable organic thin film fabrication is possible by MLD surface reaction in monolayer scale. Purging was carried out after dosing of each precursor to eliminate physically adsorbed precursor with surface. We also confirmed roughness of the organic thin film by atomic force microscopy (AFM). We deposit AC and 1,4-Butanediamine at $70^{\circ}C$ and investigated surface roughness as a function of increasing thickness of organic thin film. We confirmed precursor's functional group by IR spectrum. We calculated WVTR of organic-inorganic hybrid super-lattice epitaxial layer using Ca test. WVTR indicates super-lattice film can be possibly use as encapsulation in flexible devices.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.226.3-227
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• 2002

• 한국식품영양과학회지
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• 제27권2호
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• pp.326-332
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• 1998

The effect of mushroom extracts from Pleurotus ostreatus and Lentinus edodes on carbon tetrachloride(CCl4)-induced hepatotoxicity was investigated. Rats were administered orally each mushroom extract at the dose of 150mg/kg, foolwed by treatment with CCl4. Liver damage was produced in male Sprague-Dawley rats, after 21hrs from dosing with CCl4(0.25ml/kg) which were given intraperitoneally. Liver damage without renal injury was confirmed by measuring plasma enzyme, creatinine and blood analysis and liver analysis. Plasma aminotransferase activity, and levels of cholesterol and triglyceride were analyzed. Plasma alanine aminotransferase and aspartate aminotransferase activities were decreased by 34% and 61.5% in pretreatment group of Lentinus edodes compared with CCl4 treated group, respectively. The adminstration of all mushroom extracts led the plasma cholesterol and triglyceride levels decrease more than the CCl4-treated rats. These results suggest that Lentinus edodes extract protect liver from damage induced by CCl4.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2018년도 추계 학술논문 발표대회
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• pp.4-5
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• 2018

The water proofing sheet of synthetic polymer applies to the purification plant, the wastewater treatment center, the low waterway, the dosing tanks, etc, and when we construct these, we apply the dual waterproof by means of hot air staking welder or extruder. However, the experts skilled in the hot air welding or extruder does not use them, it can be a quality problem. Therefore, in this study, it is the purpose to verify whether the semi-automatic hot air staking welder and automatic extruder that can construct the waterproof sheet is possible in field even if it is not a professional specialist.

• 약학회지
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• 제48권1호
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• pp.55-59
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• 2004

A PVA-soft hydrogel, which is a semi-solid form in container, whereas after applying on the skin, it formed a thin layer within a few minutes. In this study, we prepared a novel type PVA-soft hydrogel containing 6-methyluracil as active drug, and the therapeutic value was characterized. To evaluate the therapeutic value of the PVA-soft hydrogel containing drug, various animal models, thermal burn model, incision & excision wound rat model were used. We also measured the wound size and breaking strength to calculate the wound healing extent after single or multiple administration. The wound size of soft hydrogel treated group decreased rapidly than that of control group after multiple dosing in excision wound model. And, the breaking strength of the soft hydrogel treated group was greater than that of control group in incision wound model.

• Membrane and Water Treatment
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• 제2권4호
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• pp.225-237
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• 2011

In this study, response of reversibility of membrane flux during chemically enhanced backwash (CEB) to changes in filtration time, filtration flux and coagulant concentration dosing during ultrafiltration (UF) process was investigated using a regression model. The model was developed via empirical modelling approach using response surface methodology. In developing the model, statistically designed UF experiments were conducted and the results compared with the model output. The results showed that the performance of CEB, evaluated in terms of the reversibility of the membrane flux, depends strongly on the changes in coagulant concentration dosage and the filtration flux. Also the response of the reversibility of membrane flux during CEB is independent of the filtration time. The variance ratio, VR << $F_{value}$ and $R^2$ = 0.98 obtained from the cross-validation experiments indicate perfect agreement of the model output with experimental results and also testify to the validity and suitability of the model to predict reversibility of the membrane flux during CEB in UF operation.

• Archives of Pharmacal Research
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• 제29권6호
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• pp.431-458
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• 2006

As we approach the completion of the first 25 years of the human immunodeficiency virus(HIV) epidemic, there have been dramatic improvements in the care of patients with HIV infection. These have prolonged life and decreased morbidity. There are twenty currently available antiretrovirals approved in the United States for the treatment of this infection. The medications, including their pharmacokinetic properties, side effects, and dosing are reviewed. In addition, the current approach to the use of these medicines is discussed. We have included a section addressing common comorbid conditions including hepatitis B and C along with tuberculosis.

• Tuberculosis and Respiratory Diseases
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• 제77권3호
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• pp.105-110
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• 2014

Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, is an important cause of morbidity and mortality. The aim of this review is to summarize the findings from clinically important publications over the last year in the area of VTE. In this review, we discuss 11 randomized controlled trials published from March 2013 to April 2014. The COAG and the EU-PACT trials indicate that pharmacogenetic testing has either no usefulness in the initial dosing of vitamin K antagonists or marginal usefulness in the Caucasian population. Recent clinical trials with novel oral anticoagulants (NOACs) have demonstrated that the efficacy and safety of rivaroxaban, apixaban, edoxaban, and dabigatran are not inferior to those of conventional anticoagulants for the treatment of VTE. The PEITHO and ULTIMA trials suggested that rescue thrombolysis or catheter-directed thrombolysis may maximize the clinical benefits and minimize the bleeding risk. Lastly, riociguat has a proven efficacy in treating chronic thromboembolic pulmonary hypertension. In the future, NOACs, riociguat, and catheter-directed thrombolysis have the potential to revolutionize the management of patients with VTE.