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Antiretroviral Therapy 2006: Pharmacology, Applications, and Special Situations  

Samuel, Rafik (Section of Infectious Diseases, Temple University School of Medicine)
Bettiker, Robert (Section of Infectious Diseases, Temple University School of Medicine)
Suh, Byung-Se (Section of Infectious Diseases, Temple University School of Medicine)
Publication Information
Archives of Pharmacal Research / v.29, no.6, 2006 , pp. 431-458 More about this Journal
Abstract
As we approach the completion of the first 25 years of the human immunodeficiency virus(HIV) epidemic, there have been dramatic improvements in the care of patients with HIV infection. These have prolonged life and decreased morbidity. There are twenty currently available antiretrovirals approved in the United States for the treatment of this infection. The medications, including their pharmacokinetic properties, side effects, and dosing are reviewed. In addition, the current approach to the use of these medicines is discussed. We have included a section addressing common comorbid conditions including hepatitis B and C along with tuberculosis.
Keywords
HIV; Antiretroviral therapy; Viral load; CD4 count; Nucleoside reverse transcriptase inhibitors; Non nucleoside reverse transcriptase inhibitors; Protease inhibitors;
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