• Title/Summary/Keyword: Dong Hae

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The Production of Functional Peptide from Whey Using Immobilized Trypsin (유청으로부터 고정화 트립신을 이용한 기능성 펩타이드의 생산)

  • Park, Yun-Joo;Yun, Yeo-Pyo;Lee, Hyung-Joo;Jang, Hae-Dong
    • Korean Journal of Food Science and Technology
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    • v.28 no.1
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    • pp.99-104
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    • 1996
  • Carbohydrate-free caseinomacropeptide (CMP) was isolated from the sweet whey powder by a precipitation method using 12% trichloroacetic acid. The yield of carbohydrate-free CMP was 2.7 g from 100 g sweet whey powder. The electrophoretic pattern and the amino acid analysis of CMP showed that isolated CMP was quite pure, indicating the precipitation with 12% trichloroacetic acid was very effective for isolating carbohydrate-free CMP from the sweet whey powder. Trypsin, covalently immobilized on pore glass beads by carbodiimide (EDC) method, was 20mg per 1g glass beads. CMP was almost completely hydrolyzed by soluble trypsin in 24hr, but not by immobilized trypsin. The tryptic hydrolysates were fractionated on a Bio-Gel P 4 column $(1.5{\times}120\;cm)$and separated peptides were tested for their capacities to inhibit platelet aggregation using a aggregometer. The hydrolysate obtained from CMP after 24hr digestion by immobilized trypsin showed the highest activity.

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Properties of Wet Noodle Changed by the Addition of Whey Powder (유청분말 첨가가 제면특성에 미치는 영향)

  • Lee, Kyoung-Hae;Kim, Kyung-Tack
    • Korean Journal of Food Science and Technology
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    • v.32 no.5
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    • pp.1073-1078
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    • 2000
  • Wet noodles were prepared with all purposed flour and whey powder, and effects of added whey powder on dough rheology and noodle quality were examined using texture profile analysis, sensory evaluation and colorimeter. The initial pasting temperature in amylograph and the maximum resistance in extensograph increased with the addition of whey powder, while the water absorption and the dough development time in farinograph and the extensibility in extensograph decreased. The weight and volume of cooked noodles decreased and turbidity of soup increased with the addition of whey powder. Sensory evaluation revealed that the texture, taste and overall acceptabillity of cooked noodle from 5% whey powder were significantly different from the others. Texture profile analysis of cooked noodles showed decrease of hardness, cohesiveness, chewiness and springiness with the increase of whey powder. L and a values of wet noodles decreased with the addition of whey powder and b value increased.

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Version Management Method for Consistency in the Grid Database (그리드 데이터베이스에서 일관성 유지를 위한 버전 관리 기법)

  • Shin, Soong-Sun;Jang, Yong-Il;Chung, Weon-Il;Lee, Dong-Wook;Eo, Sang-Hun;Bae, Hae-Young
    • Journal of Korea Multimedia Society
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    • v.11 no.7
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    • pp.928-939
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    • 2008
  • The grid database management system is used for large data processing, high availability and data integration by grid environment. It has a replica for processing performance and high availability in each node. The grid database has a problem of inconsistency, when the update is occurred with a coincidently frequent. To solve this problem, in this paper proposed a version management method for consistency in the grid database. Proposed version manager manages a version of each replica. The version manager keeps a consistency of update operation when is occurred at each node by using a pending queue and waiting queue. Also the node keeps a consistency using a priority queue. So, proposed method has stable and fast update propagation. The proposed method shows stable and faster update propagation than traditional method by performance evaluation.

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Load Balancing Method for Query Processing Based on Cache Management in the Grid Database (그리드 데이터베이스에서 질의 처리를 위한 캐쉬 관리 기반의 부하분산 기법)

  • Shin, Soong-Sun;Back, Sung-Ha;Eo, Sang-Hun;Lee, Dong-Wook;Kim, Gyoung-Bae;Chung, Weon-Il;Bae, Hae-Young
    • Journal of Korea Multimedia Society
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    • v.11 no.7
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    • pp.914-927
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    • 2008
  • Grid database management systems are used for large data processing, high availability and data integration in grid computing. Furthermore the grid database management systems are in the use of manipulating the queries that are sent to distributed nodes for efficient query processing. However, when the query processing is concentrated in a random node, it will be occurred with imbalance workload and decreased query processing. In this paper we propose a load balancing method for query processing based on cache Management in grid databases. This proposed method focuses on managing a cache in nodes by cache manager. The cache manager connects a node to area group and then the cache manager maintains a cached meta information in node. A node is used for caching the efficient meta information which is propagated to other node using cache manager. The workload of node is distributed by using caching meta information of node. This paper shows that there is an obvious improvement compared with existing methods, through adopting the proposed algorithm.

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A Study on the Fault Detection of ASIC using Dynamic Pattern Method (Dynamic Pattern 기법을 이용한 주문형 반도체 결함 검출에 관한 연구)

  • Shim, Woo-Che;Jung, Hae-Sung;Kang, Chang-Hun;Jie, Min-Seok;Hong, Gyo-Young;Ahn, Dong-Man;Hong, Seung-Beom
    • Journal of Advanced Navigation Technology
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    • v.17 no.5
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    • pp.560-567
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    • 2013
  • In this paper, it is proposed the fault detection method of the ASIC, without the Test Requirement Document(TRD), extracting internal logic circuit and analyzed the function of the ASIC using the multipurpose development program and simulation. If there don't have the TRD, it is impossible to analyze the operation of the circuit and find out the fault detection in any chip. Therefore, we make the TRD based on the analyzed logic data of the ASIC, and diagnose of the ASIC circuit at the gate level through the signal control of I/O pins using the Dynamic Pattern signal. According to the experimental results of the proposed method, we is confirmed the good performance of the fault detection capabilities which applied to the non-memory circuit.

Effect of Node Size on the Performance of the B+-tree on Flash Memory (플래시 메모리 상에서 B+-트리 노드 크기 증가에 따른 성능 평가)

  • Park, Dong-Joo;Choi, Hae-Gi
    • The KIPS Transactions:PartA
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    • v.15A no.6
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    • pp.325-334
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    • 2008
  • Flash memory is widely used as a storage medium for mobile devices such as cell phones, MP3 players, PDA's due to its tiny size, low power consumption and shock resistant characteristics. Additionally, some computer manufacturers try to replace hard-disk drives used in Laptops or personal computers with flash memory. More recently, there are some literatures on developing a flash memory-aware $B^+$-tree index for an efficient key-based search in the flash memory storage system. They focus on minimizing the number of "overwrites" resulting from inserting or deleting a sequence of key values to/from the $B^+$-tree. However, in addition to this factor, the size of a physical page allocated to a node can affect the maintenance cost of the $B^+$-tree. In this paper, with diverse experiments, we compare and analyze the costs of construction and search of the $B^+$-tree and the space requirement on flash memory as the node size increases. We also provide sorting-based or non-sorting-based algorithms to be used when inserting a key value into the node and suggest an header structure of the index node for searching a given key inside it efficiently.

Video-based Intelligent Unmanned Fire Surveillance System (영상기반 지능형 무인 화재감시 시스템)

  • Jeon, Hyoung-Seok;Yeom, Dong-Hae;Joo, Young-Hoon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.20 no.4
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    • pp.516-521
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    • 2010
  • In this paper, we propose a video-based intelligent unmanned fire surveillance system using fuzzy color models. In general, to detect heat or smoke, a separate device is required for a fire surveillance system, this system, however, can be implemented by using widely used CCTV, which does not need separate devices and extra cost. The systems called video-based fire surveillance systems use mainly a method extracting smoke or flame from an input image only. The smoke is difficult to extract at night because of its gray-scale color, and the flame color depends on the temperature, the inflammable, the size of flame, etc, which makes it hard to extract the flame region from the input image. This paper deals with a intelligent fire surveillance system which is robust against the variation of the flame color, especially at night. The proposed system extracts the moving object from the input image, makes a decision whether the object is the flame or not by means of the color obtained by fuzzy color model and the shape obtained by histogram, and issues a fire alarm when the flame is spread. Finally, we verify the efficiency of the proposed system through the experiment of the controlled real fire.

The Effects of $Y_3Al_5O_{12}$ on the Mechanical Properties of Silicon Nitride ($Y_3Al_5O_{12}$ 첨가가 질화규소 세라믹스의 제조 및 그 기계적 특성에 미치는 영향)

  • Noh, Sang-Hoon;Moon, Chang-Kwon;Jeong, Hae-Yong;Seo, Won-Chan;Yoon, Han-Ki;Kim, Bu-Ahn
    • Journal of Ocean Engineering and Technology
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    • v.21 no.6
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    • pp.95-100
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    • 2007
  • In the present work, silicon nitride was fabricated with $Y_3Al_5O_{12}$ as a sintering additive and its mechanical properties were investigated. Silicon nitride with 3, 5, and 7wt% of $Y_3Al_5O_{12}$ was prepared and sintered by a Hot Pressing (HP) technique at 1750 and $1800^{\circ}C$ for 2 h. The process was performed under different process pressures of 30 and 45 MPa. Mechanical properties (density, strength, hardness, and fracture toughness) were investigated as a function of the $Y_3Al_5O_{12}$ content in $Si_3N_4$. $Si_3N_4\;-Y_3Al_5O_{12}$ ceramics showing similar mechanical properties compared with $Si_3N_4-Y_2O_3-Al_2O_3$ ceramics. But its high temperature strength was considerably higher than that of $Si_3N_4-Y_2O_3-Al_2O_3$ ceramics.

Treatment Response and Symptomatic Changes after Eye Movement Desensitization and Reprocessing in Psychiatric Disorders Other than Posttraumatic Stress Disorder (외상후 스트레스 장애 이외의 정신 장애에 대한 EMDR 전후의 치료 반응 및 증상 변화)

  • Lee, Hae-Won;Kim, Dae-Ho;Bae, Hwal-Lip;Choi, Joon-Ho;Oh, Dong-Hoon;Park, Yong-Chon
    • Anxiety and mood
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    • v.4 no.1
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    • pp.55-61
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    • 2008
  • Objective : Eye movement desensitization and reprocessing (EMDR) has been established as an effective treatment for patients with posttraumatic stress disorder (PTSD). However, the literature is unclear as to whether EMDR is effective in the treatment of other psychiatric disorders. The purpose of this study was to evaluate the potential use of EMDR in the treatment of psychiatric disorders other than PTSD by using a clinician's impression of patient response and a subjective symptom evaluation. Methods : Seventeen diagnostically heterogenous patients without PTSD underwent an average of 4.3 sessions of EMDR. Symptom severity was assessed by the Clinical Global Impression-Change Scale (CGIC), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and Symptom Checklist-90- Revised (SCL-90-R) before and after EMDR. Those whose CGI-C scores were 'very much improved' and 'much improved' after EMDR were classified as 'responders.' The patients' before and after treatment scores of symptom severity and group differences were compared. Results : Twelve of the 17 participants (12/17, 71%) were classified as 'responders.' The patients' scores on all of the scales, with the exception of the trait anxiety scale and obsession-compulsion scale of the SCL- 90-R, significantly decreased after treatment. There was no difference in sociodemographic and clinical variables between the responders and non-responders. Conclusion : The results of our study suggest that EMDR can be a promising candidate for the treatment of patients with psychiatric disorders other than PTSD, and thus further controlled studies are needed to determine whether EMDR can be applied to various psychiatric populations.

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Immunohistochemical Expression of Receptor Tyrosine Kinase (RTK) in Canine Brain Tumors

  • Jung, Hae-Won;Song, Joong-Hyun;Yu, Do-Hyeon;An, Su-Jin;Sur, Jung-Hyang;Kim, Young Joo;Han, Donghyun;Jung, Dong-In
    • Journal of Veterinary Clinics
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    • v.36 no.6
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    • pp.319-324
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    • 2019
  • Receptor tyrosine kinases (RTK) are major promising targets in anticancer therapy in human and veterinary medicine. Using immunohistochemistry method, we evaluated the expressionof five types RTK (PDGFR-α, PDGFR-β, VEGFR 2, c-Kit and Abl) in the six canine brain tumor samples (2 meningioma, 2 astrocytoma, 1 ependymoma and 1 choroid plexus papilloma). A total of five samples expressed PDGFR-β (5/6), one sample, the choroid plexus papilloma, expressed c-Kit (1/6), and a total of two samples expressed Abl (2/6). None of the samples showed expression of PDGFR-α and VEGFR 2. We demonstrate that a significant portion of canine brain tumors express tyrosine receptors for growth factors and show that these receptors generally localize to tumor cell membranes and the cytoplasm. Evaluation of immunohistochemical expression for the RTKs PDGFR-β, c-Kit, and Alb in canine brain samples reveals an interesting potential for molecular targeting by TKIs in therapeutic studies of canine brain tumors, and more studies will be needed to assess the interactions and efficacy of these RTKs and TKIs. Based on these results, we have some evidence for novel chemotherapeutic trials using TKIs for canine nervous tumors.