• 치위생과학회지
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• 제21권1호
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• pp.70-78
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• 2021

Background: The aim of this study was to analyze the public demand for information about the job of dental hygienists by mining text data collected from the online Q & A section on an Internet portal site. Methods: Text data were collected from inquiries that were posted on the Naver Q & A section from January 2003 to July 2020 using "dental hygienist job recognition," "role recognition," "medical assistance," and "scaling" as search keywords. Text mining techniques were used to identify significant Korean words and their frequency of occurrence. In addition, the association between words was analyzed. Results: A total of 10,753 Korean words related to the job of dental hygienists were extracted from the text data. "Chi-lyo (treatment)," "chigwa (dental clinic)," "ske-illing (scaling)," "itmom (gum)," and "chia (tooth)" were the five most frequently used words. The words were classified into the following areas of job of the dental hygienist: periodontal disease treatment and prevention, medical assistance, patient care and consultation, and others. Among these areas, the number of words related to medical assistance was the largest, with sixty-six association rules found between the words, and "chi-lyo," "chigwa," and "ske-illing" as core words. Conclusion: The public demand for information about the job of dental hygienists was mainly related to "chi-lyo," "chigwa," and "ske-illing" as core words, demonstrating that scaling is recognized by the public as the job of a dental hygienist. However, the high demand for information related to treatment and medical assistance in the context of dental hygienists indicates that the job of dental hygienists is recognized by the public as being more focused on medical assistance than preventive dental care that are provided with job autonomy.

• 디지털융복합연구
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• 제19권3호
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• pp.313-318
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• 2021

질병의 치료를 위해서는 약을 정시에 정량 복용해야 할 필요가 있으나 다수의 사람들이 약의 복용 시간을 어기거나 잊어버리는 경우가 빈번하게 발생한다. 이러한 문제점을 정보기술을 이용하여 해결하기 위한 앱이 등장하고 있다. 그러나 기존의 앱의 경우, 복용 알림 기능만 제공하거나 사용자 인터페이스가 불평하고, 복용 약의 사진 등록 등이 불가능하여 사용하기 어렵다. 이러한 문제점을 해결하기 위하여 본 연구에서는 복용 알림뿐만 아니라 복용 루틴 설정, 복용여부 확인, 병원 및 약국 검색, 사용자가 복용하고 있는 약의 이미지 첨부가 가능한 스마트 약물 복용 관리 앱을 개발하였다. 본 앱을 통하여 복용 시간을 잊어버리는 빈도를 낮추고, 실제 이미지를 통한 복용 약의 확인을 통한 정확한 투약이 가능하다. 또한 복용 주기가 다른 여러 개의 약을 복용할 경우, 이를 지원하기 위한 복용 루틴 설정도 지원하고 있다. 그리고 현재 위치에서 가까운 병원 및 약국에 대한 정보를 제공하여 병원, 약국에 대한 접근성을 높일 수 있다.

• 한국콘텐츠학회논문지
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• 제21권8호
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• pp.662-674
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• 2021

대사증후군은 심혈관질환과 밀접한 연관성을 가지며, 최근 대사증후군의 예측을 통한 예방에 관심이 증가하고 있다. 본 연구의 목적은 최근 한국인을 대상으로 한 대사증후군의 발병을 예측하는 논문을 수집, 분석, 종합하여 체계적 문헌고찰을 위한 것이다. 체계적 문헌고찰을 위해 자료검색은 Pubmed, WOS의 해외DB와 DBPia, KISS의 국내DB에서 검색하였으며, 'Metabolic Syndrome', 'predict', 'Korea' 세개의 키워드를 AND 조건으로 2011~2020년에 게재된 논문을 대상으로 검색하였다. 총 560편의 논문이 검색되었고 자료선정기준에 따라 최종 22편의 논문이 선별되었다. 대사증후군 예측에 가장 활용도가 높은 변수는 WHtR(AUC=0.897)이고, 가장 많이 사용된 분석방법은 로지스틱 회귀분석(63.6%), 가장 높은 정확도를 보이는 분석방법은 XGBOOST(AUC=0.879)였다. 또한 한의학적 체질 분류를 적용하는 경우 예측 정확도가 약간 향상되었다. 본 연구 결과를 토대로 한국인의 최적의 대사증후군 예측과 관리를 위한 대규모의 지속적 연구가 수반되어야 할 것으로 생각된다.

• Fisheries and Aquatic Sciences
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• 제24권10호
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• pp.319-329
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• 2021

In the search for antibiotic alternatives from safe and effective medicinal plants against fish pathogenic bacteria, we found that a combined extract (CE) of 1:1 (w/w) ratio of Angelica gigas Nakai roots and aerial parts of Artemisia iwayomogi Kitamura showed antibacterial activity against the fish pathogenic bacteria. By antibacterial activity-guided fractionations and isolations, five compounds were isolated and identified as decursinol angelate (1), decursin (2), xanthotoxin (3), demethylsuberosin (4), and 2,4-dihydroxy-6-methoxyacetophenone (5) through spectroscopic analyses, such as nuclear magnetic resonance (NMR) and mass spectrometry (MS). Among the compounds, 1 and 2 showed the highest antibacterial activities against Streptococcus iniae and Vibrio anguillarum, showing minimum inhibitory concentrations (MICs) of 62.5-250 ㎍/mL. Compounds 3, 4, and 5 were also found to be active, with MICs of 31.25-1,000 ㎍/mL for those strains. Furthermore, active compounds, 1 and 2 in CE were simultaneously quantified using high-performance liquid chromatography-tandem MS (HPLC-MS/MS). The average contents of 1 and 2 in CE was 3.68% and 6.14%, respectively. The established method showed reliable linearity (r² > 0.99), good precision, accuracy, and specificity with intra- and inter-day variations of < 2 % and recoveries of 90.13%-108.57%. These results may be helpful for establishing the chemical profile of CE for its commercialization as an antibiotic alternative in aquaculture.

• 대한치과의료관리학회지
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• 제9권1호
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• pp.38-43
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• 2021

Based on data from the Korean Academy for Dental Administration, which has been conducting the Dental Quality Improvement (QI) Contest since 2010, we aimed to provide basic data for the development of dental quality improvement indicators by analyzing the trends of dental quality improvement activities. A total of 54 articles in the dental QI contest from 2015 to 2021 were used to search for frequently used words and to classify the quality of dental care. The criteria for the quality dimension of dental care were first classified into structure, process, and outcome, and secondary classification was performed into patient safety, timeliness, patient-centeredness, equity, efficiency, effectiveness, and accessibility. The frequently used key terms were satisfaction (five times), efficiency (four times), system (three times), and implant (three times). The activities for process evaluation were high at 62.26%, structural evaluation activities at 35.85%, and outcome evaluation activities at 1.89%. According to the components of dental care quality improvement, the activity performed under efficiency was the highest (33.96%), followed by patient-centeredness (18.87%), effectiveness (16.98%), patient safety (15.09%), accessibility (5.66%), timeliness (1.89%), and the equity (1.89%). QI activities in dental hospitals were mainly activities on improvement in structure and process, as well as activities on efficiency, patient-centeredness, effectiveness, and patient safety.

• 융합정보논문지
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• 제12권4호
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• pp.212-218
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• 2022

본 연구는 의료소비자의 만성질환 유무에 따른 정보탐색행태를 파악하고자 수행되었다. 이를 위해 2016년 2월 9일에서 2월 11일까지 서울 소재 대학병원에 방문한 환자들을 대상으로 설문조사를 실시하였으며, SPSS 26.0 통계 패키지를 활용하여, 총 240명의 자료를 분석하였다. 주요 분석 결과는 다음과 같다. 첫째, 만성질환자들은 만성질환이 없는 사람들보다, 전문가 정보원과 경험적 정보원을 많이 이용한 것으로 나타났다. 둘째, 질환과 관련해서는 영양관리, 운동 관리 및 동일 질환자들의 사례를 많이 탐색하는 것으로 나타났다. 마지막으로 병원과 관련해서 만성질환자들은 대기시간과 진료비를 많이 알아본 것으로 나타났다. 본 연구는 만성질환자들의 수요를 반영한 효율적인 정보제공과 마케팅전략 수립의 기초자료를 제공한 의의가 있다.

• Genomics & Informatics
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• 제20권3호
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• pp.35.1-35.9
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• 2022

Microsatellites or simple sequence repeats are motifs of 1 to 6 nucleotides in length present in both coding and non-coding regions of DNA. These are found widely distributed in the whole genome of prokaryotes, eukaryotes, bacteria, and viruses and are used as molecular markers in studying DNA variations, gene regulation, genetic diversity and evolutionary studies, etc. However, in vitro microsatellite identification proves to be time-consuming and expensive. Therefore, the present research has been focused on using an in-house built java pipeline to identify, analyse, design primers and find related statistics of perfect and compound microsatellites in the seven complete genome sequences of coronavirus, including the genome of coronavirus disease 2019, where the host is Homo sapiens. Based on search criteria among seven genomic sequences, it was revealed that the total number of perfect simple sequence repeats (SSRs) found to be in the range of 76 to 118 and compound SSRs from 01 to10, thus reflecting the low conversion of perfect simple sequence to compound repeats. Furthermore, the incidence of SSRs was insignificant but positively correlated with genome size (R² = 0.45, p > 0.05), with simple sequence repeats relative abundance (R² = 0.18, p > 0.05) and relative density (R² = 0.23, p > 0.05). Dinucleotide repeats were the most abundant in the coding region of the genome, followed by tri, mono, and tetra. This comparative study would help us understand the evolutionary relationship, genetic diversity, and hypervariability in minimal time and cost.

• 동의신경정신과학회지
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• 제33권4호
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• pp.401-424
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• 2022

Objectives: As effective treatments for dementia are lacking in Western medicine, complementary and alternative medicine (CAM) is considered a useful option. While the quality of life (QoL) is a vital outcome for patients with dementia, the QoL of patients receiving CAM for dementia remains ambiguous. This study aimed to determine the effect of CAM on QoL outcomes in dementia patients. Methods: A search was performed using the keywords "dementia," "Alzheimer's," "cognitive impairment," "Chinese," "Korean," "oriental," "herbal," "acupuncture," and "quality of life". All quantitative data were synthesized using R version 4.1.1. Results: Twenty-five randomized controlled trials (RCTs), 16 pre-post trials, and two cohort studies were selected for the systematic review. QoL in Alzheimer's disease (QOL-AD) (n=11, 25.6%) and geriatric QoL in dementia (GQOL-D, n=9, 20.9%) were the most utilized QoL instruments. Significant benefits in QoL were observed after receiving mind, body, combined mind and body, nursing, oriental medicine, and acupuncture therapies. In the meta-analysis, the combined effect was shown to significantly increase QOL-AD compared to before CAM interventions (standardized mean difference, SMD: 0.507; 95% confidence interval (CI), 0.191~0.824; p<0.01). The overall synthesized estimates in the GQOL-D showed a significantly improved QoL (SMD: 0.537, 95% CI: 0.238~0.837 p<0.01; one group; SMD: 1.465, 95% CI: 0.934~1.996, p<0.01). The seven studies assessing the cost-effectiveness of CAM reported uncertain outcomes. Conclusions: This study showed that CAM interventions benefited patients with dementia by improving their QoL. While additional standardized research is required, CAMs are suggested as effective clinical management for patients with dementia. They are also suggested as complementing therapies for these patients.

• Human Ecology Research
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• 제60권1호
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• pp.1-20
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• 2022

This paper presents a social network analysis of changes in Home Economics education content loaded on YouTube before and after the outbreak of COVID-19. From January 1, 2008 to June 30, 2021, a basic analysis was conducted of 761 Home Economics education videos loaded on YouTube, using NetMiner 4.3 to analyze important keywords and the centrality of video titles and full texts. Before COVID-19, there were 164 Home Economics education videos posted on YouTube, increasing significantly to 597 following the emergence of the pandemic. In both periods, there was more middle school content than high school content. The content in the child-family field was the most, and the main keywords were youth and family. Before COVID-19, a performance evaluation indicated that the proportion of student content was high, whereas after the outbreak of the disease, teacher content increased significantly due to the effect of distance learning. However, compared with video use, the self-expression and participation of users were lower in both periods. The centrality analysis indicated that in the title, 'family' exhibited a high degree of both centrality and eigenvector centrality over the entire period. Degree centrality of the video title was found to be high in the order of class, online, family, management, etc. after the outbreak of COVID-19, and the connection of keywords was strong overall. Eigenvector centrality indicated that career, search, life, and design were influential keywords before COVID-19, while class, youth, online, and development were influential keywords after COVID-19.

• Journal of Gastric Cancer
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• 제22권2호
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• pp.83-93
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• 2022

Background: To analyze the short- and long-term clinical outcomes of 2 reconstruction methods after distal gastrectomy for gastric cancer. Methods: Three keywords, "gastric neoplasm," "distal gastrectomy," and "reconstruction," were used to search PubMed. We selected only randomized controlled trial that compared the anastomosis methods. A total of 11 papers and 8 studies were included in this meta-analysis. All statistical analyses were performed using the R software. Results: Among short-term clinical outcomes, a shorter operation time, reduced morbidity, and shorter hospital stay were found for Billroth type I (B-I) than for Roux-en-Y (RNY) reconstruction in the meta-analysis (P<0.001, P=0.048, P<0.001, respectively). When comparing Billroth type II (B-II) to RNY, the operation time was shorter for B-II than for RNY (P<0.019), but there were no differences in morbidity or length of hospital stay (P=0.500, P=0.259, respectively).Regarding long-term clinical outcomes related to reflux, there were significantly fewer incidents of reflux esophagitis, reflux gastritis, and bile reflux (P=0.035, P<0.001, P=0.019, respectively) for RNY than for B-I in the meta-analysis, but there was no difference between the 2 methods in residual food (P=0.545). When comparing B-II to RNY, there were significantly fewer incidents of reflux gastritis (P<0.001) for RNY than for B-II, but the amount of residual food and patient weight gain showed no difference. Conclusion: B-I had the most favorable short-term outcomes, but RNY was more advantageous for long-term outcomes than for other methods. Surgeons should be aware of the advantages and disadvantages of each type of anastomosis and select the appropriate method.