• Title/Summary/Keyword: Disable

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Molecular cloning and characterization of novel human JNK2 (MAPK9) transcript variants that show different stimulation activities on AP-1

  • Wang, Pingzhang;Xiong, Ying;Ma, Chuan;Shi, Taiping;Ma, Dalong
    • BMB Reports
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    • v.43 no.11
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    • pp.738-743
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    • 2010
  • The c-Jun $NH_2$-terminal kinase (JNK) signaling pathway participates in many physiological functions. In the current study we reported the cloning and characterization of five novel JNK2 transcript variants, which were designated as $JNK2\alpha3$, $JNK2\alpha4$, $JNK2\beta3$, $JNK2\gamma1$ and $JNK2\gamma2$, respectively. Among them, $JNK2\alpha4$ and $JNK2\gamma2$ are potential non-coding RNA because they contain pre-mature stop codons. Both $JNK2\alpha3$ and $JNK2\beta3$ contain an intact kinase domain, and both encode a protein product of 46 kDa, the same as those of $JNK2\alpha1$ and $JNK2\beta1$. $JNK2\gamma1$ contains a disrupted kinase domain and it showed a disable function. When over-expressed in mammalian cells, $JNK2\alpha3$ showed higher activity on AP-1 than that of $JNK2\beta3$ and $JNK2\gamma1$. Furthermore, $JNK2\alpha3$ and $JNK2\beta3$ showed different levels of substrate phosphorylation, although they both could promote the proliferation of 293T cells. Our results further demonstrate that JNK2 isoforms preferentially target different substrates and may regulate the expression of various target genes.

Gifted Education in China in a non-coginitive factors centered (중국의 영재교육 -비지적 요인을 중심으로 한 북경팔중의 사례-)

  • 고효단;심재영;김언주
    • Proceedings of the Korean Society for the Gifted Conference
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    • 2003.11a
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    • pp.133-163
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    • 2003
  • The purpose of the present study is (1) to examine chinese gifted education type, growth factors of the gifted children, and non-coginitive factors, (2) to analysis gifted education strategy of Peking eighth middle school, (3) to investigate gifted education method of Peking eighth middle school, (4) to study practical effects of gifted education method of Peking eighth middle school, (5) to study of the application for the gifted education in Korea. The results of the present study were as follows: (1) The types of the gifted education in China are advanced placement, skipping the coursework, extracurriculawork, individual guidence, and gifted education for the disable gifted. (2) Gifted education strategy of Peking eighth middle school was analysed. It is forming a Trinity of science research, education, and teacher. A teacher is generally observing and students are mainly one's own man of education. (3) Gifted education method of Peking eighth middle school was investigated. There are eight non-cognitive education principles: a personal character, emotion, supporting of family education, physical education, and encouragement. (4) Practical effects of gifted education method of Peking eighth middle school was studied. The school had a good reputation evaluation. (5) The application for the gifted education in Korea was studied. The eight non-cognitive education principles is able to apply for the gifted education in Korea.

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A Study for Pressure Difference and Critical Velocity by Pressurization of Elevator Shaft at High Rise Apartment (고층 공동주택의 승강로가압을 이용한 차압 및 방연풍속에 관한 연구)

  • Park, Kyung-Hwan;Yoon, Myong-O
    • Fire Science and Engineering
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    • v.25 no.4
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    • pp.89-93
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    • 2011
  • It is not recommended that elevator use for egress at (super) high rise buildings because elevator shaft main roles to spread of fire smoke. But in North America used to protect this area by elevator shaft pressurization. These tests are performed at high rise apartment to verify that elevator shaft pressurization can protect to spread of fire smoke or not. and verify to used for egress at fire. Pressurization at elevator shaft make pressure difference of 50 Pa all floor at 150 CMM because this method have low friction loss from air flow. Also when dwelling door and elevator door are opened that critical velocity is performed to protect of back-layering from fire room for escape routs by 180 CMM. Therefore through out these pressurization tests by elevator shaft are estimated to have less overpressure because supply air difference are low between to satisfy critical velocity at one door opened and maintain to pressure difference all doors closed. Finally we verified that disable or residual people can use elevator for egress at fire by elevator shaft pressurization.

Blindness Experience of Family of Persons with Unilateral Acquired Blindness (일측 중도시각장애인과 가족의 체험연구)

  • Kim, Kyung Ran
    • Korean Parent-Child Health Journal
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    • v.18 no.2
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    • pp.47-57
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    • 2015
  • Purpose: The purpose of this study is to discover the nature from the life experience of a person with unilateral acquired blindness and his/her family after losing the eyesight and adapting in the environment and to find the meaning of life and how to solve the problem in psychosocial aspect. Methods: This study uses one of the qualitative research methods which explains how families with the unilateral acquired blind perceive blindness after experiencing it and observes how they signify it. starts with interest in lifestyles of individuals and their families and tries to understand the subjective existences of participants in accessible ways and draw the experiences after becoming one-side blind. It cyclically uses deductive verification process through inductive method and establishing hypothesis using materials. Results: According to the results of this study, unilateral acquired blindness studies, due to shattered life, they did not know what to do. Also, discomfort from struggling in a big tunnel and even will to live were found. trying to go out to the world, seeing the new world, and trying to encourage myself, strong attachment to life was shown to by saying, appeared. Each includes sub-topics such as feeling abandoned after confirmed the blindness, feeling disappointed to doctors, family, and friends, trying to live with hope, struggling in a tunnel with thinking how to live, closing the mind from the world, seeing outside the world in the midst of struggling, trying to forget the past with the will of life, having hope to live with care of family, and trying to keep the rest vision. Conclusion: Firstly, in nursing aspect for their adaptation, programs for disable people and nursing intervention focused on their families should be developed. Secondly, since it can be economic and psychological burden for their families and acquaintances, it is necessary to support the blind so that they can find fitted rehabilitation programs and come back to society. Thirdly, active participation of health care providers may influence social interest the improvement of national welfare policy for the unilateral acquired blind.

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End-to-End Performance of Packet Aggregation Transmission on MANET under DDoS Attacks (DDoS 공격이 있는 MANET에서 패킷취합전송의 종단간 성능)

  • Kim, Young-Dong
    • The Journal of the Korea institute of electronic communication sciences
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    • v.9 no.6
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    • pp.689-694
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    • 2014
  • DDoS attacks on MANET makes disable any node which support network function, cause critical results as a stopping of entire network service or separation to some parts. Packet aggregation, which gather some pieces of short length into a certain length of data, improves transmission performances on MANETs. In this paper, some effects on transmission performance of packet aggregation transmission be caused by DDoS Attacks are measured and analyzed in point of end-to-end level. MANET simulator, based on NS-2, is used for measurement end-to-end performances. MOS, connection rate, delay and packet loss rate is used as performance parameters. VoIP traffic is used for object service measurement. Finally, it is suggested that number of packet aggregation is more then 4 for keeping the transmission quality over MANETs under DDoS attacks.

Access Control using Secured Container-based Virtualization (보안 컨테이너 가상화 기반 접근 제어)

  • Jeong, Dong-hwa;Lee, Sunggyu;Shin, Youngsang;Park, Hyuncheol
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.10a
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    • pp.330-334
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    • 2017
  • Container-based virtualization reduces performance overhead compared with other virtualization technologies and guarantees an isolation of each virtual execution environment. So, it is being studied to block access to host resources or container resources for sandboxing in restricted system resource like embedded devices. However, because security threats which are caused by security vulnerabilities of the host OS or the security issues of the host environment exist, the needs of the technology to prevent an illegal accesses and unauthorized behaviors by malware has to be increased. In this paper, we define additional access permissions to access a virtual execution environment newly and control them in kernel space to protect attacks from illegal access and unauthorized behaviors by malware and suggest the Container Access Control to control them. Also, we suggest a way to block a loading of unauthenticated kernel driver to disable the Container Access Control running in host OS by malware. We implement and verify proposed technologies on Linux Kernel.

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The Modified Block Matching Algorithm for a Hand Tracking of an HCI system (HCI 시스템의 손 추적을 위한 수정 블록 정합 알고리즘)

  • Kim Jin-Ok
    • Journal of Internet Computing and Services
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    • v.4 no.4
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    • pp.9-14
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    • 2003
  • A GUI (graphical user interface) has been a dominant platform for HCI (human computer interaction). A GUI - based interaction has made computers simpler and easier to use. The GUI - based interaction, however, does not easily support the range of interaction necessary to meet users' needs that are natural. intuitive, and adaptive. In this paper, the modified BMA (block matching algorithm) is proposed to track a hand in a sequence of an image and to recognize it in each video frame in order to replace a mouse with a pointing device for a virtual reality. The HCI system with 30 frames per second is realized in this paper. The modified BMA is proposed to estimate a position of the hand and segmentation with an orientation of motion and a color distribution of the hand region for real - time processing. The experimental result shows that the modified BMA with the YCbCr (luminance Y, component blue, component red) color coordinate guarantees the real - time processing and the recognition rate. The hand tracking by the modified BMA can be applied to a virtual reclity or a game or an HCI system for the disable.

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Analysis of Complications of Ambulatory General Anesthesia after Discharge in Patients Who are Taking Anticonvulsant (항경련제를 복용하고 있는 지적장애 환자의 외래전신마취 하 치과치료 후 합병증 발생 조사 연구)

  • Cha, Min-Joo;Seo, Kwang-Suk;Kim, Mi-Seon;Kim, Hyun-Jeong
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.14 no.2
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    • pp.95-100
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    • 2014
  • Background: About 60% of patients with epilepsy showed a variety of complications after returning home. The purpose of this study is to get further information and to help in the anesthetic management of the disable patients with epilepsy. Methods: After searching the outpatient anesthesia list of Seoul National University Dental Hospital clinic of the disabled from September 2010 to March 2012, we found total 83 patient cases who were taking antiepileptic drugs. A nurse of anethesiology department called to the patient's home after general anesthesia and got surveys with questionnaires form filled with complications at home. We enrolled total of 51 patients who agreed to participate this survey. And we also reviewed pre-anesthesia evaluation sheet, anesthesia record, and recovery and discharge record. Results: 11 of 51 (21.6%) patients had seizure convulsion at home within 1 weeks. 33.4% of patients who had at least once seizure attack per week had a seizure attack within 3 days. And 50% of once a month frequency patients had a seizure attack within 1 week. 33% of 1 - 3 seizure attacks per year patient group had a convulsion within 1 week. But there was no seizure attack within 1 week in whom had no seizure attack history during more than 1 year. Conclusions: After dental treatment, patient taking anticonvulsant have so many complications-especially seizure, more than we respected. We need more research about handle these problems.

Development of Personal Mobility Safety Driving Assistance System Using CNN-Based Object Detection and Boarding Detection Sensor (합성곱 신경망 기반 물체 인식과 탑승 감지 센서를 이용한 개인형 이동수단 주행 안전 보조 시스템 개발)

  • Son, Kwon Joong;Bae, Sung Hoon;Lee, Hyun June
    • Journal of the Korea Convergence Society
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    • v.12 no.10
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    • pp.211-218
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    • 2021
  • A recent spread of personal mobility devices such as electric kickboards has brought about a rapid increase in accident cases. Such vehicles are susceptible to falling accidents due to their low dynamic stability and lack of outer protection chassis. This paper presents the development of an automatic emergency braking system and a safe starting system as driving assistance devices for electric kickboards. The braking system employed artificial intelligence to detect nearby threaening objects. The starting system was developed to disable powder to the motor until when the driver's boarding is confirmed. This study is meaningful in that it proposes the convergence technology of advanced driver assistance systems specialized for personal mobility devices.

An Analysis of Factors Impact of Disabled's Disability Acceptance on Job Satisfaction (장애인의 장애수용이 일 만족도에 미치는 영향 요인의 융합적 분석)

  • Suk, Mal-Sook;Cho, Ouk-Sun
    • Journal of Convergence for Information Technology
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    • v.8 no.6
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    • pp.317-326
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    • 2018
  • The study was design to examine the degree of disability and the moderating effect of discrimination experiences on the job satisfaction of the disabled workers' disability acceptance. The 8th year data from the Panel Survey of Employment for the Disabled was used to extracting 2270 disable wage-workers who met the study purpose as a sample. The moderate effect was verified by using regression analysis. As a result, first, the disability acceptance of disabled wage workers presented a positive effect on job satisfaction. Second, the effect of disability acceptance on job satisfaction differed by the degree of disability. Third, the effect of disability acceptance on job satisfaction differed by the discrimination experiences. Which refers that the study identify the cushion of degree of disability and the discrimination experiences, which play an important role in the job satisfaction of the disabled wage workers. Therefore, this study suggests that it can be used as a practical implication and basic data for the program developments improving the job satisfaction of disabled wage workers.