• Title/Summary/Keyword: Diffusion-weighted

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Evaluation of Treatment Response Using Diffusion-Weighted MAI in Metastatic Spines (척추 전이암에서 확산강조 자기공명 영상을 이용한 치료반응의 평가)

  • Lee, Jang-Jin;Shin, Sei-One
    • Journal of Yeungnam Medical Science
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    • v.18 no.1
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    • pp.30-38
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    • 2001
  • Background: The purpose of this study was to evaluate the usefulness of diffusion-weighted magnetic resonance imaging for monitoring the response to radiation therapy in metastatic bone marrow of the spines. Materials and Methods: Twenty-one patients with metastatic bone marrow of the spines were examined with MRI. Diffusion-weighted and spin-echo MRI were performed in 10 patients before and after radiation therapy with or without systemic chemotherapy, and performed in 11 patients after radiation therapy alone. Follow up spin-echo and diffusion-weighted MRI were obtained at 1 to 6 months after radiation therapy according to patients' condition. The diffusion-weighted imaging sequence was based on reversed fast imaging with steady-state precession (PSIF). Signal intensity changes of the metastatic bone marrows before and after radiation therapy on conventional spin-echo sequence MRI and diffusion-weighted MRI were evaluated. Bone marrow contrast ratios and signal-to-noise ratios before and after radiation therapy of diffusion- weighted MRI were analyzed. Results: All metastatic bone marrow of the spinal bodies were hyperintense to normal bone marrow of the spinal bodies on pretreatment diffusion-weighted MRI and positive bone marrow contrast ratios(p<0.001), and hypointense to normal spinal bodies on posttreatment diffusion-weighted MRI and negative bone marrow contrast ratios(p<0.001). The signal to noise ratios after treatment decreased comparing with those of pretreatment. Decreased signal intensity of the metastatic bone marrows on diffusion-weighted MRI began to be observed at average more than one month after the initiation of the radiation therapy. Conclusion: These results suggest that diffusion-weighted MRI would be an excellent method for monitoring the response to therapy of metastatic bone marrow of the spinal bodies, however, must be investigated in a larger series of patients with longer follow up period.

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Changes in SNR and ADC According to the Increase in b Value in Liver Diffusion-Weighted Images

  • Cho, Jae-Hwan;Kim, Ham-Gyum
    • Journal of Magnetics
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    • v.17 no.3
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    • pp.219-224
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    • 2012
  • In the present study, changes in signal-to-noise ratio (SNR) and apparent diffusion coefficient (ADC) of the diffusion-weighted images in the normal livers were investigated using changes in b values in 1.5 T MR (magnetic resonance) instruments. Respective diffusion-weighted images and ADC map images were obtained from 20 healthy individuals by increasing b values from 50 to 400 and 800 $s/mm^2$ using 1.5T MR scanner between January 2011 and November 2011. At each ADC map image obtained at each b value, ADCs in the right hepatic lobe, spleen and kidney were measured. As a result, ADCs of the right hepatic lobe, spleen and kidney have gradually decreased in the diffusion-weighted images in accordance with the reduced b value. This outcome may be used as preliminary data for applications to various abdominal diseases.

Diffusion-Weighted MR Imaging in Biopsy-Proven Creutzfeldt-Jakob Disease

  • Hyo-Cheol Kim;Kee-Hyun Chang;In Chan Song;Sang Hyun Lee;Bae Ju Kwon;Moon Hee Han;Sang-Yun Kim
    • Korean Journal of Radiology
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    • v.2 no.4
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    • pp.192-196
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    • 2001
  • Objective: To compare conventional and diffusion-weighted MR imaging in terms of their depiction of the abnormalities occurring in Creutzfeldt-Jakob disease. Materials and Methods: We retrospectively analyzed the findings of conventional (T2-weighted and fluid-attenuated inversion recovery) and diffusion-weighted MR imaging in four patients with biopsy-proven Creutzfeldt-Jakob disease. The signal intensity of the lesion was classified by visual assessment as markedly high, slightly high, or isointense, relative to normal brain parenchyma. Results: Both conventional and diffusion-weighted MR images demonstrated bilateral high signal intensity in the basal ganglia in all four patients. Cortical lesions were observed on diffusion-weighted MR images in all four, and on fluid-attenuated inversion recovery MR images in one, but in no patient on T2-weighted images. Conventional MR images showed slightly high signal intensity in all lesions, while diffusion-weighted images showed markedly high signal intensity in most. Conclusion: Diffusion-weighted MR imaging is more sensitive than its conventional counterpart in the depiction of Creutzfeldt-Jakob disease, and permits better detection of the lesion in both the cerebral cortices and basal ganglia.

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Weighted error diffusion in PDP (PDP에서 가중치 오차확산 보정)

  • Jung, Han-Yung;Lee, Dong-Ho
    • Proceedings of the KIEE Conference
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    • 2005.05a
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    • pp.179-181
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    • 2005
  • There is asymmetric in horizontal and vertical side of PDP cell. Every vertical line has BM(Black Mask) to improve luminance contrast. When error diffusion is processed in PDP system, these problems make an error bigger. In 4 inch PDP system, every red, green, blue color of test pattern is presented and each luminance is measured. That is called horizontal(H), diagonal right(R), diagonal left(L) and vertical(V). In red channel, high luminance descending order is V-H-R-L. In green channel, V-H-L-R. In blue channel, V-M-R=L. After average luminance of each direction is calculated. new weighted error diffusion(Weighted ED) is proposed. In digital image signal processing, the error in weighted ED is differ from ED's. The image of weighted ED is more less error compare to conventional ED and close to original image. As the gray level linearity and big size panel is adopted, weighted ED could produce good image.

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PERELMAN TYPE ENTROPY FORMULAE AND DIFFERENTIAL HARNACK ESTIMATES FOR WEIGHTED DOUBLY NONLINEAR DIFFUSION EQUATIONS UNDER CURVATURE DIMENSION CONDITION

  • Wang, Yu-Zhao
    • Bulletin of the Korean Mathematical Society
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    • v.58 no.6
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    • pp.1539-1561
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    • 2021
  • We prove Perelman type 𝒲-entropy formulae and differential Harnack estimates for positive solutions to weighed doubly nonlinear diffusion equation on weighted Riemannian manifolds with CD(-K, m) condition for some K ≥ 0 and m ≥ n, which are also new for the non-weighted case. As applications, we derive some Harnack inequalities.

Evaluation of the Usefulness of PROPELLER (periodically rotated overlapping parallel lines with enhanced reconstruction) Technique to Reduce the Magnetic susceptibility artifact (Magnetic susceptibility artifact를 줄이기 위한 PROPELLER 확산강조영상기법의 유용성에 대한 평가)

  • Cho, Jae-Hwan
    • Journal of Digital Contents Society
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    • v.11 no.1
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    • pp.73-78
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    • 2010
  • This study attempted to examine whether the propeller diffusion weighted image method may remove magnetic susceptibility artifacts caused by metallic materials. A comparison of occurrence rates of magnetic susceptibility artifacts in the four regions, both temporal lobes, pons, and orbit, between b = 0 and b = 1,000 s/mm2 images was made after obtaining echo-planar diffusion weighted image, propeller diffusion weighted image, and ADC map images, respectively, from a total of 20 patients who had MRI shots taken of their brain and were found to be with retained metallic foreign bodies within their teeth using a 3.0T MR scanner. In the case of echo-planar diffusion weighted image technique, the presence of metallic materials may bring in some limits on accurate diagnosis due to magnetic susceptibility artifacts, while the propeller diffusion weighted image technique where magnetic susceptibility artifacts decrease is expected to be more useful in ensuring accurate diagnosis in the clinical context.

Serial Magnetic Resonance Images of a Right Middle Cerebral Artery Infarction : Persistent Hyperintensity on Diffusion-Weighted MRI Over 8 Months

  • Son, Seung-Nam;Choi, Dae-Seob;Choi, Nack-Cheon;Lim, Byeong-Hoon
    • Journal of Korean Neurosurgical Society
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    • v.50 no.4
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    • pp.388-391
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    • 2011
  • A lesion that is hyperintense on diffusion-weighted imaging (DWI) and hypointense on the apparent diffusion coefficient (ADC) map is a characteristic magnetic resonance imaging (MRI) finding in acute ischemic infarction. In some cases, however, these findings can persist for a few months after infarct onset. It is thought that these finding reflect the different evolution speeds of the infarcted tissue. We report a patient with a right middle cerebral artery territory infarction with persistent hyperintensity on DWI and hypointensity on the ADC map for over 8 months. To our knowledge, this is the most persistent case of hyperintensity lesion on DWI and the serial MRI images of this patient provide important information on the evolution of infarcted tissue.

Magnetic Resonance Imaging Evaluation of the Prostate in Normal Dogs

  • Cho, Yu-Gyeong;Choi, Ho-jung;Lee, Ki-ja;Lee, Youngwon
    • Journal of Veterinary Clinics
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    • v.37 no.6
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    • pp.317-323
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    • 2020
  • The aims of this study were to describe the appearance and size of the normal canine prostate using magnetic resonance (MR) imaging and to calculate the apparent diffusion coefficient (ADC) values. MR images were obtained from seven intact male beagle dogs using a 1.5 T MR unit. The sequences included pre- and post-contrast T1- and T2-weighted imaging with and without fat saturation. The signal intensity of the prostate was compared with the adjacent musculature, fat, and urine in the urinary bladder. We recorded the mean prostatic length, width, and height and the length of the sixth lumbar vertebral body (L6). In addition, the prostatic length (rL), width (rW), and height (rH) ratios to L6 were calculated. Diffusion-weighted images of the prostate were obtained and ADC values were calculated. The prostate was bilobed and oval-shaped, homogenous on T1-weighted images, and heterogeneous with radiating lines on T2-weighted images. Post-contrast T1-weighted sequences showed contrast enhancement of the central and radiating striations. The prostatic capsule was clearly identified on post-contrast T1-weighted images with fat saturation. The ADC values were 1.72-2.04 × 10-3mm2/sec (mean, 1.88 × 10-3mm2/sec). Knowledge of the normal appearance of the prostate on MR images is essential to assess prostatic diseases in dogs.

The quantitative analysis of Diffusion Weighted Imaging in Breast MRI (유방 MRI 검사에서 확산강조영상의 정량적 분석)

  • Cho, Jae-Hwan;Kim, Hyeon-Ju;Hong, Yin-Sik;Lee, Hae-Kag
    • Journal of the Korean Society of Radiology
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    • v.5 no.3
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    • pp.149-154
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    • 2011
  • The purpose of this study was to examine the usefulness of diffusion weighted images in breast MRI by performing a quantitative comparative analysis in patients diagnosed with DCIS. On a 3.0T MR scanner, diffusion weighted images and ADC map images were obtained from 20 patients histologically diagnosed with ductal carcinoma in situ (DCIS). The findings from the quantitative image analysis are the following: The diffusion weighted images showed higher SNR and CNR at the lesion area. In addition, the ADC values were lower at the lesion area.

Electron Microscopy and MR Imaging Findings in Embolic Effects

  • Park Byung-Rae;Koo Bong-Oh
    • Biomedical Science Letters
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    • v.10 no.4
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    • pp.367-373
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    • 2004
  • Evaluated the hyperacute embolic effects of triolein and oleic acid in cat brains by using MR image and electron microscopy. In fat embolism, free fatty acid is more toxic than neutral fat in terms of tissue damage. T2-Weighted imaging, diffusion-weighted imaging, and contrast-enhanced T1-weighted imaging were performed in cat brains after the injection of triolein (group 1, n=8) or oleic acid (group 2, n=10) into the internal carotid artery. MR image were quantitatively assessed by comparing the lesions with their counterparts on T2-weighted images, apparent diffusion coefficient (ADC) maps, and contrast-enhanced T1-weighted images. Electron microscopic findings in group 1 were compared with those in group 2. Qualitatively, MR images revealed two types of lesions. Type 1 lesions were hyperintense on diffusion-weighted images and hypointense of ADC maps. Type 2 lesions were isointense or mildly hyperintense on diffusion-weighted images and isointense on ADC maps. Quantitatively, the signal intensity rations of type 1 lesions in group 2 specimens were significantly higher on T2-weighted images (P=.013)/(P=.027) and lower on ADC maps compared with those of group 1. Electron microscopy of type 1 lesions in both groups revealed more prominent widening of the perivascular space and swelling of the neural cells in groups 1. MR and electron microscopic data on cerebral fat embolism induced by either triolein or oleic acid revealed characteristics suggestive of both vasogenic and cytotoxic edema in the hyperacute stage. Tissue damage appeared more severe in the oleic acid group than in the triolein group.

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